A Practical Stereoselective Synthesis and Novel Cocrystallizations of an Amphiphatic SGLT-2 Inhibitor von Deshpande, Prashant P, Singh, Janak, Pullockaran, Annie, Kissick, Thomas, Ellsworth, Bruce A, Gougoutas, Jack Z, Dimarco, John, Fakes, Michael, Reyes, Mayra, Lai, Chiajen, Lobinger, Hidegard, Denzel, Theo, Ermann, Peter, Crispino, Gerard, Randazzo, Michael, Gao, Zenrong, Randazzo, Renee, Lindrud, Mark, Rosso, Victor, Buono, Frederic, Doubleday, Wendel W, Leung, Simon, Richberg, Pricilla, Hughes, David, Washburn, William N, Meng, Wei, Volk, Kevin J, Mueller, Richard H

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Novel Synthesis of the Hexahydroimidazo[1,5b]isoquinoline Scaffold: Application to the Synthesis of Glucocorticoid Receptor Modulators von Xiao, Hai-Yun, Wu, Dauh-Rurng, Malley, Mary F, Gougoutas, Jack Z, Habte, Sium F, Cunningham, Mark D, Somerville, John E, Dodd, John H, Barrish, Joel C, Nadler, Steven G, Dhar, T. G. Murali

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Discovery of potent and selective nonsteroidal indazolyl amide glucocorticoid receptor agonists von Sheppeck, James E., Gilmore, John L., Xiao, Hai-Yun, Dhar, T.G. Murali, Nirschl, David, Doweyko, Arthur M., Sack, Jack S., Corbett, Martin J., Malley, Mary F., Gougoutas, Jack Z., Mckay, Lorraine, Cunningham, Mark D., Habte, Sium F., Dodd, John H., Nadler, Steven G., Somerville, John E., Barrish, Joel C.

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Discovery of Potent and Muscle Selective Androgen Receptor Modulators through Scaffold Modifications von Li, James J, Sutton, James C, Nirschl, Alexandra, Zou, Yan, Wang, Haixia, Sun, Chongqing, Pi, Zulan, Johnson, Rebecca, Krystek, Stanley R, Seethala, Ramakrishna, Golla, Rajasree, Sleph, Paul G, Beehler, Blake C, Grover, Gary J, Fura, Aberra, Vyas, Viral P, Li, Cindy Y, Gougoutas, Jack Z, Galella, Michael A, Zahler, Robert, Ostrowski, Jacek, Hamann, Lawrence G

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Synthesis of Novel Potent Dipeptidyl Peptidase IV Inhibitors with Enhanced Chemical Stability:  Interplay between the N-Terminal Amino Acid Alkyl Side Chain and the Cyclopropyl Gro... von Magnin, David R, Robl, Jeffrey A, Sulsky, Richard B, Augeri, David J, Huang, Yanting, Simpkins, Ligaya M, Taunk, Prakash C, Betebenner, David A, Robertson, James G, Abboa-Offei, Benoni E, Wang, Aiying, Cap, Michael, Xin, Li, Tao, Li, Sitkoff, Doree F, Malley, Mary F, Gougoutas, Jack Z, Khanna, Ashish, Huang, Qi, Han, Song-Ping, Parker, Rex A, Hamann, Lawrence G

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A Novel Application of a Pd(0)-Catalyzed Nucleophilic Substitution Reaction to the Regio- and Stereoselective Synthesis of Lactam Analogues of the Epothilone Natural Products von Borzilleri, Robert M, Zheng, Xiaoping, Schmidt, Robert J, Johnson, James A, Kim, Soong-Hoon, DiMarco, John D, Fairchild, Craig R, Gougoutas, Jack Z, Lee, Francis Y. F, Long, Byron H, Vite, Gregory D

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Calcium Entry Blockers and Activators: Conformational and Structural Determinants of Dihydropyrimidine Calcium Channel Modulators von Rovnyak, George C, Kimball, S. David, Beyer, Barbara, Cucinotta, Gabriella, DiMarco, John D, Gougoutas, Jack, Hedberg, Anders, Malley, Mary, McCarthy, James P

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N-Aryl-oxazolidin-2-imine Muscle Selective Androgen Receptor Modulators Enhance Potency through Pharmacophore Reorientation von Nirschl, Alexandra A, Zou, Yan, Krystek, Stanley R, Sutton, James C, Simpkins, Ligaya M, Lupisella, John A, Kuhns, Joyce E, Seethala, Ramakrishna, Golla, Rajasree, Sleph, Paul G, Beehler, Blake C, Grover, Gary J, Egan, Donald, Fura, Aberra, Vyas, Viral P, Li, Yi-Xin, Sack, John S, Kish, Kevin F, An, Yongmi, Bryson, James A, Gougoutas, Jack Z, DiMarco, John, Zahler, Robert, Ostrowski, Jacek, Hamann, Lawrence G

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Discovery and Development of 5-[(5S,9R)-9- (4-Cyanophenyl)-3-(3,5-dichlorophenyl)-1- methyl-2,4-dioxo-1,3,7-triazaspiro[4.4]non- 7-yl-methyl]-3-thiophenecarboxylic Acid (BMS-587101... von Potin, Dominique, Launay, Michele, Monatlik, Francoise, Malabre, Patrice, Fabreguettes, Maud, Fouquet, Andre, Maillet, Magali, Nicolai, Eric, Dorgeret, Loïc, Chevallier, François, Besse, Dominique, Dufort, Monique, Caussade, François, Ahmad, Syed Z, Stetsko, Dawn K, Skala, Stacey, Davis, Patricia M, Balimane, Praveen, Patel, Karishma, Yang, Zheng, Marathe, Punit, Postelneck, Jennifer, Townsend, Robert M, Goldfarb, Valentina, Sheriff, Steven, Einspahr, Howard, Kish, Kevin, Malley, Mary F, DiMarco, John D, Gougoutas, Jack Z, Kadiyala, Pathanjali, Cheney, Daniel L, Tejwani, Ravindra W, Murphy, Denette K, Mcintyre, Kim W, Yang, Xiaoxia, Chao, Sam, Leith, Leslie, Xiao, Zili, Mathur, Arvind, Chen, Bang-Chi, Wu, Daugh-Rurng, Traeger, Sarah C, McKinnon, Murray, Barrish, Joel C, Robl, Jeffrey A, Iwanowicz, Edwin J, Suchard, Suzanne J, Dhar, T. G. Murali

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Synthesis, characterization, and crystal structures of M(DO3A) (M = iron, gadolinium) and Na[M(DOTA)] (M = Fe, yttrium, Gd) von Chang, C. Allen, Francesconi, Lynn C, Malley, Mary F, Kumar, Krishan, Gougoutas, Jack Z, Tweedle, Michael F, Lee, Daniel W, Wilson, Lon J

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Cannabinoid CB1 receptor ligand binding and function examined through mutagenesis studies of F200 and S383 von Sitkoff, Doree F., Lee, Ning, Ellsworth, Bruce A., Huang, Qi, Kang, Liya, Baska, RoseAnn, Huang, Yanting, Sun, Chongqing, Pendri, Annapurna, Malley, Mary F., Scaringe, Raymond P., Gougoutas, Jack Z., Reggio, Patricia H., Ewing, William R., Pelleymounter, Mary Ann, Carlson, Kenneth E.

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Urea based CCR3 antagonists employing a tetrahydro-1,3-oxazin-2-one spacer von Dhar, T.G. Murali, Yang, Guchen, Davies, Paul, Malley, Mary F., Gougoutas, Jack Z., Wu, Dauh-Rurng, Barrish, Joel C., Carter, Percy H.

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Novel 1,4-Homofragmentation via an α-Lactone von Godfrey, Jollie D, Fox, Rita T, Buono, Frederic G, Gougoutas, Jack Z, Malley, Mary F

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Synthesis, Structure Proof, and Biological Activity of Epothilone Cyclopropanes von Johnson, James, Kim, Soong-Hoon, Bifano, Marc, DiMarco, John, Fairchild, Craig, Gougoutas, Jack, Lee, Francis, Long, Byron, Tokarski, John, Vite, Gregory

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Efficient Asymmetric Synthesis of the Vasopeptidase Inhibitor BMS-189921 von Singh, Janak, Kronenthal, David R, Schwinden, Mark, Godfrey, Jollie D, Fox, Rita, Vawter, Edward J, Zhang, Bo, Kissick, Thomas P, Patel, Bharat, Mneimne, Omar, Humora, Michael, Papaioannou, Chris G, Szymanski, Walter, Wong, Michael K. Y, Chen, Chien K, Heikes, James E, DiMarco, John D, Qiu, Jun, Deshpande, Rajendra P, Gougoutas, Jack Z, Mueller, Richard H

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SAR and pH Stability of Cyano-Substituted Epothilones von Regueiro-Ren, Alicia, Leavitt, Kenneth, Kim, Soong-Hoon, Höfle, Gerhard, Kiffe, Michael, Gougoutas, Jack Z, DiMarco, John D, Lee, Francis Y. F, Fairchild, Craig R, Long, Byron H, Vite, Gregory D

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Arylcyclopropanecarboxyl Guanidines as Novel, Potent, and Selective Inhibitors of the Sodium Hydrogen Exchanger Isoform-1 von Ahmad, Saleem, Doweyko, Lidia M, Dugar, Sundeep, Grazier, Nyeemah, Ngu, Khehyong, Wu, Shung C, Yost, Kenneth J, Chen, Bang-Chi, Gougoutas, Jack Z, DiMarco, John D, Lan, Shih-Jung, Gavin, Brian J, Chen, Alice Y, Dorso, Charles R, Serafino, Randy, Kirby, Mark, Atwal, Karnail S

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Dihydropyrimidine calcium channel blockers: 2-heterosubstituted 4-aryl-1,4-dihydro-6-methyl-5-pyrimidinecarboxylic acid esters as potent mimics of dihydropyridines von Atwal, Karnail S, Rovnyak, George C, Schwartz, Joseph, Moreland, Suzanne, Hedberg, Anders, Gougoutas, Jack Z, Malley, Mary F, Floyd, David M

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Conformational Switching and the Synthesis of Spiro[2H-indol]-3(1H)-ones by Radical Cyclization von Sulsky, Richard, Gougoutas, Jack Z, DiMarco, John, Biller, Scott A

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An Alternate Route to 2-Amino-3-nitro-5-bromo-4-picoline: Regioselective Pyridine Synthesis via 2-Nitramino-picoline Intermediate von Bhattacharya, Apurba, Purohit, Vikram C, Deshpande, Prashant, Pullockaran, Annie, Grosso, John A, DiMarco, John D, Gougoutas, Jack Z

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