Lentiviral protein delivery of meganucleases in human cells mediates gene targeting and alleviates toxicity von He, C, Gouble, A, Bourdel, A, Manchev, V, Poirot, L, Paques, F, Duchateau, P, Edelman, A, Danos, O

Volltext

P1420: PRE‐CLINICAL PROOF OF CONCEPT DEMONSTRATES ROBUST ACTIVITY OF UCART20X22 DUAL CAR T‐CELLS FOR THE TREATMENT OF B‐CELL MALIGNANCIES von Aranda Orgilles, B., Chion‐Sotinel, I., Grudman, S., Mumford, B., Dixon, C., Duchateau, P., Galetto, R., Gouble, A., Poirot, L.

Volltext

Variable correction of Artemis deficiency by I-Sce1-meganuclease-assisted homologous recombination in murine hematopoietic stem cells von Rivière, J, Hauer, J, Poirot, L, Brochet, J, Souque, P, Mollier, K, Gouble, A, Charneau, P, Fischer, A, Pâques, F, de Villartay, J-P, Cavazzana, M

Volltext

Synchronous and regulated expression of two AU-binding proteins, AUF1 and HuR, throughout murine development von GOUBLE, Agnès, MORELLO, Dominique

Volltext

1233 - Gene Editing/Gene Therapies: NON-VIRAL DNA DELIVERY ASSOCIATED TO TALEN® GENE EDITING LEADS TO HIGHLY EFFICIENT CORRECTION OF SICKLE CELL MUTATION IN LONG-TERM REPOPULATING... von Moiani, A., Letort, G., Lizot, S., Hong, P., Temburni-Black, S., Felix, T., Chalumeau, A., Miccio, A., Gouble, A., Juillerat, A., Duclert, A., Duchateau, P., Valton, J.

Volltext

Gene Editing/Gene Therapies: NON-VIRAL DNA DELIVERY ASSOCIATED TO TALEN® GENE EDITING LEADS TO HIGHLY EFFICIENT CORRECTION OF SICKLE CELL MUTATION IN LONG-TERM REPOPULATING HEMATOP... von Moiani, A., Letort, G., Lizot, S., Hong, P., Temburni-Black, S., Felix, T., Chalumeau, A., Miccio, A., Gouble, A., Juillerat, A., Duclert, A., Duchateau, P., Valton, J.

Volltext

Engineered I-CreI Derivatives Cleaving Sequences from the Human XPC Gene can Induce Highly Efficient Gene Correction in Mammalian Cells von Arnould, Sylvain, Perez, Christophe, Cabaniols, Jean-Pierre, Smith, Julianne, Gouble, Agnès, Grizot, Sylvestre, Epinat, Jean-Charles, Duclert, Aymeric, Duchateau, Philippe, Pâques, Frédéric

Volltext

A new player in oncogenesis: AUF1/hnRNPD overexpression leads to tumorigenesis in transgenic mice von Gouble, Agnàs, Grazide, Solàne, Meggetto, Fabienne, Mercier, Pascale, Delsol, Georges, Morello, Dominique

Volltext

Meganucleases for gene therapy von Paques, F, Smith, J, Gouble, A, Galetto, R, Arnould, S, Duchateau, P, Desseaux, C

Volltext

Meganucleases and Gene Therapy: Different Strategies von Paques, F, Galetto, R, Poirot, L, Grosse, S, Arnould, S, Gouble, A, Duchateau, P, Desseaux, C, Smith, J

Volltext

Meganucleases for Genome Surgery von Paques, F, Galetto, R, Poirot, L, Grosse, S, Arnould, S, Gouble, A, Duchateau, P, Desseaux, C, Smith, J

Volltext

Factors affecting double-strand break-induced homologous recombination in mammalian cells von Perez, Christophe, Guyot, Valérie, Cabaniols, Jean-Pierre, Gouble, Agnès, Micheaux, Beatrice, Smith, Julie, Leduc, Sophie, Pâques, Frédéric, Duchateau, Philippe

Volltext

Meganucleases: novel anti-viral approach and therapeutic strategies von Arnould, S, Poirot, L, Smith, J, Gailledrat, M, Gouble, A, Galetto, R, Duchateau, P, Paques, F, Desseaux, C

Volltext

Activation of constitutive 5-hydroxytryptamine(1B) receptor by a series of mutations in the BBXXB motif: positioning of the third intracellular loop distal junction and its G(o)alp... von Pauwels, P J, Gouble, A, Wurch, T

Volltext

Impaired gametogenesis in mice that overexpress the RNA-binding protein HuR von Levadoux-Martin, Marilyne, Gouble, Agnès, Jégou, Bernard, Vallet-Erdtmann, Virginie, Auriol, Jacques, Mercier, Pascale, Morello, Dominique

Volltext

Meganucleases for gene therapy von Paques, Frederic, Duchateau, Philippe, Smith, Julianne, Gouble, Agnes, Perez, Christophe, Cabaniols, Jean-Pierre, Grizot, Sylvestre, Galetto, Roman, Daboussi, Fayza, Delacote, Fabien, Cedrone, Frederic, Epinat, Jean-Charles, Arnould, Sylvain, Duclert, Aymeric

Volltext

Gene editing of PKLR gene in human hematopoietic progenitors through 5' and 3' UTR modified TALEN mRNA von Quintana-Bustamante, Oscar, Fañanas-Baquero, S, Orman, I, Torres, Raul, Duchateau, P, Poirot, L, Gouble, A, Bueren, Juan, Segovia, J. C, Universitat Autònoma de Barcelona

Volltext bestellen

Gene editing of PKLR gene in human hematopoietic progenitors through 5' and 3' UTR modified TALEN mRNA von Quintana-Bustamante, O, Fañanas-Baquero, S, Orman, I, Torres, Raul, Duchateau, P, Poirot, L, Gouble, A, Bueren, Juan, Segovia, J. C, Universitat Autònoma de Barcelona

Volltext bestellen

Allogeneic TCRαβ deficient CAR T-cells targeting CD123 in acute myeloid leukemia von Sugita, Mayumi, Galetto, Roman, Zong, Hongliang, Ewing-Crystal, Nathan, Trujillo-Alonso, Vicenta, Mencia-Trinchant, Nuria, Yip, Winnie, Filipe, Stephanie, Lebuhotel, Celine, Gouble, Agnès, Hassane, Duane C., Smith, Julianne, Roboz, Gail J., Guzman, Monica L.

Volltext

Targeting CD123 in blastic plasmacytoid dendritic cell neoplasm using allogeneic anti-CD123 CAR T cells von Cai, Tianyu, Gouble, Agnès, Black, Kathryn L., Skwarska, Anna, Naqvi, Ammar S., Taylor, Deanne, Zhao, Ming, Yuan, Qi, Sugita, Mayumi, Zhang, Qi, Galetto, Roman, Filipe, Stéphanie, Cavazos, Antonio, Han, Lina, Kuruvilla, Vinitha, Ma, Helen, Weng, Connie, Liu, Chang-Gong, Liu, Xiuping, Konoplev, Sergej, Gu, Jun, Tang, Guilin, Su, Xiaoping, Al-Atrash, Gheath, Ciurea, Stefan, Neelapu, Sattva S., Lane, Andrew A., Kantarjian, Hagop, Guzman, Monica L., Pemmaraju, Naveen, Smith, Julianne, Thomas-Tikhonenko, Andrei, Konopleva, Marina

Volltext