Effects of an Anti-TSLP Antibody on Allergen-Induced Asthmatic Responses von Gauvreau, Gail M, O'Byrne, Paul M, Boulet, Louis-Philippe, Wang, Ying, Cockcroft, Donald, Bigler, Jeannette, FitzGerald, J. Mark, Boedigheimer, Michael, Davis, Beth E, Dias, Clapton, Gorski, Kevin S, Smith, Lynn, Bautista, Edgar, Comeau, Michael R, Leigh, Richard, Parnes, Jane R

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Talimogene Laherparepvec in Combination With Ipilimumab in Previously Untreated, Unresectable Stage IIIB-IV Melanoma von Puzanov, Igor, Milhem, Mohammed M, Minor, David, Hamid, Omid, Li, Ai, Chen, Lisa, Chastain, Michael, Gorski, Kevin S, Anderson, Abraham, Chou, Jeffrey, Kaufman, Howard L, Andtbacka, Robert H I

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Oncolytic Virotherapy Promotes Intratumoral T Cell Infiltration and Improves Anti-PD-1 Immunotherapy von Ribas, Antoni, Dummer, Reinhard, Puzanov, Igor, VanderWalde, Ari, Andtbacka, Robert H.I., Michielin, Olivier, Olszanski, Anthony J., Malvehy, Josep, Cebon, Jonathan, Fernandez, Eugenio, Kirkwood, John M., Gajewski, Thomas F., Chen, Lisa, Gorski, Kevin S., Anderson, Abraham A., Diede, Scott J., Lassman, Michael E., Gansert, Jennifer, Hodi, F. Stephen, Long, Georgina V.

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Phase I, Pharmacokinetic, and Pharmacodynamic Study of AMG 479, a Fully Human Monoclonal Antibody to Insulin-Like Growth Factor Receptor 1 von TOLCHER, Anthony W, SARANTOPOULOS, John, KAISER, Brianne, MIN ZHU, HONGJIE DENG, FRIBERG, Greg, PUZANOV, Igor, PATNAIK, Amita, PAPADOPOULOS, Kyriakos, LIN, Chia-Chi, RODON, Jordi, MURPHY, Barbara, ROTH, Bruce, MCCAFFERY, Ian, GORSKI, Kevin S

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Oncolytic Virotherapy Promotes Intratumoral T Cell Infiltration and Improves Anti-PD-1 Immunotherapy von Ribas, Antoni, Dummer, Reinhard, Puzanov, Igor, VanderWalde, Ari, Andtbacka, Robert H.I., Michielin, Olivier, Olszanski, Anthony J., Malvehy, Josep, Cebon, Jonathan, Fernandez, Eugenio, Kirkwood, John M., Gajewski, Thomas F., Chen, Lisa, Gorski, Kevin S., Anderson, Abraham A., Diede, Scott J., Lassman, Michael E., Gansert, Jennifer, Hodi, F. Stephen, Long, Georgina V.

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Synthetic TLR Agonists Reveal Functional Differences between Human TLR7 and TLR8 von Gorden, Keith B, Gorski, Kevin S, Gibson, Sheila J, Kedl, Ross M, Kieper, William C, Qiu, Xiaohong, Tomai, Mark A, Alkan, Sefik S, Vasilakos, John P

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Talimogene laherparepvec upregulates immune-cell populations in non-injected lesions: findings from a phase II, multicenter, open-label study in patients with stage IIIB–IVM1c mela... von Malvehy, Josep, Samoylenko, Igor, Schadendorf, Dirk, Gutzmer, Ralf, Grob, Jean-Jacques, Sacco, Joseph J, Gorski, Kevin S, Anderson, Abraham, Pickett, Cheryl A, Liu, Kate, Gogas, Helen

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First in Human Phase I Trial of 852A, a Novel Systemic Toll-like Receptor 7 Agonist, to Activate Innate Immune Responses in Patients with Advanced Cancer von Dudek, Arkadiusz Z, Yunis, Carla, Harrison, Lester I, Kumar, Sandeep, Hawkinson, Ronald, Cooley, Sarah, Vasilakos, John P, Gorski, Kevin S, Miller, Jeffrey S

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Distinct indirect pathways govern human NK-cell activation by TLR-7 and TLR-8 agonists von Gorski, Kevin S., Waller, Emily L., Bjornton-Severson, Jacqueline, Hanten, John A., Riter, Christie L., Kieper, William C., Gorden, Keith B., Miller, Jeffrey S., Vasilakos, John P., Tomai, Mark A., Alkan, Sefik S.

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Homeostasis of human NK cells is not IL-15 dependent von Lebrec, Herve, Horner, Michelle J, Gorski, Kevin S, Tsuji, Wayne, Xia, Dong, Pan, Wei-Jian, Means, Gary, Pietz, Greg, Li, Nianyu, Retter, Marc, Shaffer, Kathy, Patel, Neha, Narayanan, Padma K, Butz, Eric A

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Cutting Edge: Expression of Functional CD137 Receptor by Dendritic Cells von Wilcox, Ryan A, Chapoval, Andrei I, Gorski, Kevin S, Otsuji, Mizuto, Shin, Tahiro, Flies, Dallas B, Tamada, Koji, Mittler, Robert S, Tsuchiya, Haruo, Pardoll, Drew M, Chen, Lieping

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Inhibition of activation-induced death of dendritic cells and enhancement of vaccine efficacy via blockade of MINOR von Wang, Tianhong, Jiang, Qiong, Chan, Camie, Gorski, Kevin S., McCadden, Erin, Kardian, David, Pardoll, Drew, Whartenby, Katharine A.

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Tu1725 TARGETING IMPROVED TREG SELECTIVITY WITH THE IL-2 MUTEIN EFAVALEUKIN ALFA: RATIONALE FOR IL-2 THERAPY IN ULCERATIVE COLITIS von Firoozbakht, Farshid, Sarkar, Nandita, Gorski, Kevin, Tchao, Nadia

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Efficacy analysis of MASTERKEY-265 phase 1b study of talimogene laherparepvec (T-VEC) and pembrolizumab (pembro) for unresectable stage IIIB-IV melanoma von Long, Georgina V., Dummer, Reinhard, Ribas, Antoni, Puzanov, Igor, VanderWalde, Ari, Andtbacka, Robert Hans Ingemar, Michielin, Olivier, Olszanski, Anthony J., Malvehy, Josep, Cebon, Jonathan S., Fernandez, Eugenio, Kirkwood, John M., Gajewski, Thomas, Gause, Christine K., Chen, Lisa, Gorski, Kevin, Anderson, Abraham, Kaufman, David Ross, Chou, Jeffrey, Hodi, F. Stephen

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Sustained Improvement in UAS7 After 16-Week Treatment With Tezepelumab in Biologic-Naïve Adults with CSU: Results of the Phase 2b INCEPTION Study von Maurer, Marcus, McLaren, Julie, Chon, Yun, Gorski, Kevin, Bernstein, Jonathan, Hayama, Koremasa, Jain, Vipul, Sofen, Howard, Ponnarambil, Sandhia, Molfino, Nestor

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Tu1476: EFAVALEUKIN ALFA IS A NOVEL IL-2 MUTEIN THAT SELECTIVELY EXPANDS REGULATORY T CELLS: PHASE 1 RESULTS AND RATIONALE FOR CLINICAL INVESTIGATION IN ULCERATIVE COLITIS von Firoozbakht, Farshid, Tchao, Nadia, Sarkar, Nandita, Gorski, Kevin, Hu, Xuguang, Rauter, Ingrid, Rossi, Claudia Pena

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NK1.1+ cells mediate the antitumor effects of a dual Toll-like receptor 7/8 agonist in the disseminated B16-F10 melanoma model von Dumitru, Calin D., Antonysamy, Mary A., Gorski, Kevin S., Johnson, Dave D., Reddy, Laxma G., Lutterman, Jody L., Piri, Melissa M., Proksch, Joel, McGurran, Sean M., Egging, Elaine A., Cochran, Felicia R., Lipson, Kenneth E., Tomai, Mark A., Gullikson, Gary W.

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Amg 592 Is an Investigational IL-2 Mutein That Induces Highly Selective Expansion of Regulatory T Cells von Tchao, Nadia, Gorski, Kevin S, Yuraszeck, Theresa, Sohn, Sue J, Ishida, Katsuhiko, Wong, Hansen, Park, Kyong

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Transduction of donor hematopoietic stem-progenitor cells with Fas ligand enhanced short-term engraftment in a murine model of allogeneic bone marrow transplantation von Whartenby, Katharine A., Straley, Erin E., Kim, Heeje, Racke, Frederick, Tanavde, Vivek, Gorski, Kevin S., Cheng, Linzhao, Pardoll, Drew M., Civin, Curt I.

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847 The Fully Human Anti-IL-15 Antibody AMG 714, in Development for Celiac and Refractory Celiac Disease, Does Not Reduce Circulating Numbers of Human Natural Killer Cells or Precl... von Gorski, Kevin, Butz, Eric, Leon, Francisco, Lebrec, Herve, Tsuji, Wayne H

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