Discovery of ATR kinase inhibitor berzosertib (VX-970, M6620): Clinical candidate for cancer therapy von Gorecki, Lukas, Andrs, Martin, Rezacova, Martina, Korabecny, Jan

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SAR study to find optimal cholinesterase reactivator against organophosphorous nerve agents and pesticides von Gorecki, Lukas, Korabecny, Jan, Musilek, Kamil, Malinak, David, Nepovimova, Eugenie, Dolezal, Rafael, Jun, Daniel, Soukup, Ondrej, Kuca, Kamil

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Profiling donepezil template into multipotent hybrids with antioxidant properties von Mezeiova, Eva, Spilovska, Katarina, Nepovimova, Eugenie, Gorecki, Lukas, Soukup, Ondrej, Dolezal, Rafael, Malinak, David, Janockova, Jana, Jun, Daniel, Kuca, Kamil, Korabecny, Jan

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Effects of Novel Tacrine Derivatives on Mitochondrial Energy Metabolism and Monoamine Oxidase Activity—In Vitro Study von Hroudova, Jana, Novakova, Tereza, Korabecny, Jan, Malinak, David, Gorecki, Lukas, Fisar, Zdenek

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Development of versatile and potent monoquaternary reactivators of acetylcholinesterase von Gorecki, Lukas, Hepnarova, Vendula, Karasova, Jana Zdarova, Hrabinova, Martina, Courageux, Charlotte, Dias, José, Kucera, Tomas, Kobrlova, Tereza, Muckova, Lubica, Prchal, Lukas, Malinak, David, Jun, Daniel, Musilek, Kamil, Worek, Franz, Nachon, Florian, Soukup, Ondrej, Korabecny, Jan

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7-Methoxytacrine-p-Anisidine Hybrids as Novel Dual Binding Site Acetylcholinesterase Inhibitors for Alzheimer's Disease Treatment von Korabecny, Jan, Andrs, Martin, Nepovimova, Eugenie, Dolezal, Rafael, Babkova, Katerina, Horova, Anna, Malinak, David, Mezeiova, Eva, Gorecki, Lukas, Sepsova, Vendula, Hrabinova, Martina, Soukup, Ondrej, Jun, Daniel, Kuca, Kamil

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Synthesis, in vitro screening and molecular docking of isoquinolinium-5-carbaldoximes as acetylcholinesterase and butyrylcholinesterase reactivators von Malinak, David, Dolezal, Rafael, Hepnarova, Vendula, Hozova, Miroslava, Andrys, Rudolf, Bzonek, Petr, Racakova, Veronika, Korabecny, Jan, Gorecki, Lukas, Mezeiova, Eva, Psotka, Miroslav, Jun, Daniel, Kuca, Kamil, Musilek, Kamil

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Countermeasures in organophosphorus intoxication: pitfalls and prospects von Gorecki, Lukas, Soukup, Ondrej, Korabecny, Jan

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Clinical Candidates Targeting the ATR-CHK1-WEE1 Axis in Cancer von Gorecki, Lukas, Andrs, Martin, Korabecny, Jan

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Midazolam - A diazepam replacement for the management of nerve agent-induced seizures von Gorecki, Lukas, Pejchal, Jaroslav, Torruellas, Carilyn, Korabecny, Jan, Soukup, Ondrej

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Physicochemistry shapes bioactivity landscape of pan-ABC transporter modulators: Anchor point for innovative Alzheimer's disease therapeutics von Namasivayam, Vigneshwaran, Stefan, Katja, Gorecki, Lukas, Korabecny, Jan, Soukup, Ondrej, Jansson, Patric Jan, Pahnke, Jens, Stefan, Sven Marcel

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Rational design, synthesis, and evaluation of uncharged, “smart” bis-oxime antidotes of organophosphate-inhibited human acetylcholinesterase von Gorecki, Lukas, Gerlits, Oksana, Kong, Xiaotian, Cheng, Xiaolin, Blumenthal, Donald K., Taylor, Palmer, Ballatore, Carlo, Kovalevsky, Andrey, Radić, Zoran

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Oxime K203: a drug candidate for the treatment of tabun intoxication von Gorecki, Lukas, Soukup, Ondrej, Kucera, Tomas, Malinak, David, Jun, Daniel, Kuca, Kamil, Musilek, Kamil, Korabecny, Jan

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Uncharged mono- and bisoximes: In search of a zwitterion to countermeasure organophosphorus intoxication von Gorecki, Lukas, Markova, Aneta, Hepnarova, Vendula, Zivna, Natalie, Junova, Lucie, Hrabinova, Martina, Janousek, Jiri, Kobrlova, Tereza, Prchal, Lukas, Jun, Daniel, Soukup, Ondrej, Horn, Gabriele, Worek, Franz, Marek, Jan, Korabecny, Jan

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Corrigendum to Pro-cognitive effects of dual tacrine derivatives acting as cholinesterase inhibitors and NMDA receptor antagonists “Biomed. Pharmacother. 176 (2024) 116821” von Chvojkova, Marketa, Kolar, David, Kovacova, Katarina, Cejkova, Lada, Misiachna, Anna, Hakenova, Kristina, Gorecki, Lukas, Horak, Martin, Korabecny, Jan, Soukup, Ondrej, Vales, Karel

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Pro-cognitive effects of dual tacrine derivatives acting as cholinesterase inhibitors and NMDA receptor antagonists von Chvojkova, Marketa, Kolar, David, Kovacova, Katarina, Cejkova, Lada, Misiachna, Anna, Hakenova, Kristina, Gorecki, Lukas, Horak, Martin, Korabecny, Jan, Soukup, Ondrej, Vales, Karel

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7-Azaindole, 2,7-diazaindole, and 1H-pyrazole as core structures for novel anticancer agents with potential chemosensitizing properties von Gorecki, Lukas, Muthna, Darina, Merdita, Sara, Andrs, Martin, Kucera, Tomas, Havelek, Radim, Muckova, Lubica, Kobrlova, Tereza, Soukup, Jiri, Krupa, Petr, Prchal, Lukas, Soukup, Ondrej, Roh, Jaroslav, Rezacova, Martina, Korabecny, Jan

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Rational design, synthesis, and evaluation of uncharged, "smart" bis-oxime antidotes of organophosphate-inhibited human acetylcholinesterase (vol 295, pg 4079, 2020) von Gorecki, Lukas, Gerlits, Oksana, Kong, Xiaotian, Cheng, Xiaolin, Blumenthal, Donald K., Taylor, Palmer, Ballatore, Carlo, Kovalevsky, Andrey, Radic, Zoran

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Structure-activity relationships of dually-acting acetylcholinesterase inhibitors derived from tacrine on N-methyl-d-Aspartate receptors von Gorecki, Lukas, Misiachna, Anna, Damborsky, Jiri, Dolezal, Rafael, Korabecny, Jan, Cejkova, Lada, Hakenova, Kristina, Chvojkova, Marketa, Karasova, Jana Zdarova, Prchal, Lukas, Novak, Martin, Kolcheva, Marharyta, Kortus, Stepan, Vales, Karel, Horak, Martin, Soukup, Ondrej

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Reply to Comment on "Cysteine-Targeted Insecticides against A. gambiae Acetylcholinesterase Are Neither Selective nor Reversible Inhibitors" von Andrys, Rudolf, Gorecki, Lukas, Korabecny, Jan, Musilek, Kamil

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