Mithramycin induces promoter reprogramming and differentiation of rhabdoid tumor von Chasse, Maggie H, Johnson, Benjamin K, Boguslawski, Elissa A, Sorensen, Katie M, Rosien, Jessica E, Kang, Min H, Reynolds, C Patrick, Heo, Lyong, Madaj, Zachary B, Beddows, Ian, Foxa, Gabrielle E, Kitchen‐Goosen, Susan M, Williams, Bart O, Triche, Timothy J, Grohar, Patrick J

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Trabectedin Inhibits EWS-FLI1 and Evicts SWI/SNF from Chromatin in a Schedule-dependent Manner von Harlow, Matt L, Chasse, Maggie H, Boguslawski, Elissa A, Sorensen, Katie M, Gedminas, Jenna M, Kitchen-Goosen, Susan M, Rothbart, Scott B, Taslim, Cenny, Lessnick, Stephen L, Peck, Anderson S, Madaj, Zachary B, Bowman, Megan J, Grohar, Patrick J

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Carbon source availability drives nutrient utilization in CD8+ T cells von Kaymak, Irem, Luda, Katarzyna M., Duimstra, Lauren R., Ma, Eric H., Longo, Joseph, Dahabieh, Michael S., Faubert, Brandon, Oswald, Brandon M., Watson, McLane J., Kitchen-Goosen, Susan M., DeCamp, Lisa M., Compton, Shelby E., Fu, Zhen, DeBerardinis, Ralph J., Williams, Kelsey S., Sheldon, Ryan D., Jones, Russell G.

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Innate control of actin nucleation determines two distinct migration behaviours in dendritic cells von Vargas, Pablo, Maiuri, Paolo, Bretou, Marine, Sáez, Pablo J., Pierobon, Paolo, Maurin, Mathieu, Chabaud, Mélanie, Lankar, Danielle, Obino, Dorian, Terriac, Emmanuel, Raab, Matthew, Thiam, Hawa-Racine, Brocker, Thomas, Kitchen-Goosen, Susan M., Alberts, Arthur S., Sunareni, Praveen, Xia, Sheng, Li, Rong, Voituriez, Raphael, Piel, Matthieu, Lennon-Duménil, Ana-Maria

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Ketolysis drives CD8+ T cell effector function through effects on histone acetylation von Luda, Katarzyna M., Longo, Joseph, Kitchen-Goosen, Susan M., Duimstra, Lauren R., Ma, Eric H., Watson, McLane J., Oswald, Brandon M., Fu, Zhen, Madaj, Zachary, Kupai, Ariana, Dickson, Bradley M., DeCamp, Lisa M., Dahabieh, Michael S., Compton, Shelby E., Teis, Robert, Kaymak, Irem, Lau, Kin H., Kelly, Daniel P., Puchalska, Patrycja, Williams, Kelsey S., Krawczyk, Connie M., Lévesque, Dominique, Boisvert, François-Michel, Sheldon, Ryan D., Rothbart, Scott B., Crawford, Peter A., Jones, Russell G.

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Small-Molecule Intramimics of Formin Autoinhibition: A New Strategy to Target the Cytoskeletal Remodeling Machinery in Cancer Cells von LASH, L. Leanne, WALLAR, Bradley J, TURNER, Julie D, VROEGOP, Steven M, KILKUSKIE, Robert E, KITCHEN-GOOSEN, Susan M, XU, H. Eric, ALBERTS, Arthur S

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Repression of LKB1 by miR-17∼92 Sensitizes MYC-Dependent Lymphoma to Biguanide Treatment von Izreig, Said, Gariepy, Alexandra, Kaymak, Irem, Bridges, Hannah R., Donayo, Ariel O., Bridon, Gaëlle, DeCamp, Lisa M., Kitchen-Goosen, Susan M., Avizonis, Daina, Sheldon, Ryan D., Laister, Rob C., Minden, Mark D., Johnson, Nathalie A., Duchaine, Thomas F., Rudoltz, Marc S., Yoo, Sanghee, Pollak, Michael N., Williams, Kelsey S., Jones, Russell G.

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LKB1 controls inflammatory potential through CRTC2-dependent histone acetylation von Compton, Shelby E., Kitchen-Goosen, Susan M., DeCamp, Lisa M., Lau, Kin H., Mabvakure, Batsirai, Vos, Matthew, Williams, Kelsey S., Wong, Kwok-Kin, Shi, Xiaobing, Rothbart, Scott B., Krawczyk, Connie M., Jones, Russell G.

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Lurbinectedin Inhibits the EWS-WT1 Transcription Factor in Desmoplastic Small Round Cell Tumor von Gedminas, Jenna M, Kaufman, Rebecca, Boguslawski, Elissa A, Gross, Amy C, Adams, Marie, Beddows, Ian, Kitchen-Goosen, Susan M, Roberts, Ryan D, Grohar, Patrick J

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Endometrial hyperplasia with loss of APC in a novel population of Lyz2-expressing mouse endometrial epithelial cells von Kitchen-Goosen, Susan M, Schumacher, Heather, Good, Julie, Patterson, Amanda L, Boguslawski, Elissa A, West, Richard A, Williams, Bart O, Hostetter, Galen, Agnew, Dalen W, Teixeira, Jose M, Alberts, Arthur S

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Desmoplastic small round cell tumor is dependent on the EWS-WT1 transcription factor von Gedminas, Jenna M., Chasse, Maggie H., McBrairty, Mitchell, Beddows, Ian, Kitchen-Goosen, Susan M., Grohar, Patrick J.

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Lurbinectedin Inactivates the Ewing Sarcoma Oncoprotein EWS-FLI1 by Redistributing It within the Nucleus von Harlow, Matt L, Maloney, Nichole, Roland, Joseph, Guillen Navarro, Maria Jose, Easton, Matthew K, Kitchen-Goosen, Susan M, Boguslawski, Elissa A, Madaj, Zachary B, Johnson, Ben K, Bowman, Megan J, D'Incalci, Maurizio, Winn, Mary E, Turner, Lisa, Hostetter, Galen, Galmarini, Carlos María, Aviles, Pablo M, Grohar, Patrick J

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CDK9 Blockade Exploits Context-dependent Transcriptional Changes to Improve Activity and Limit Toxicity of Mithramycin for Ewing Sarcoma von Flores, Guillermo, Everett, Joel H., Boguslawski, Elissa A., Oswald, Brandon M., Madaj, Zachary B., Beddows, Ian, Dikalov, Sergey, Adams, Marie, Klumpp-Thomas, Carleen A., Kitchen-Goosen, Susan M., Martin, Scott E., Caplen, Natasha J., Helman, Lee J., Grohar, Patrick J.

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13C metabolite tracing reveals glutamine and acetate as critical in vivo fuels for CD8 T cells von Ma, Eric H, Dahabieh, Michael S, DeCamp, Lisa M, Kaymak, Irem, Kitchen-Goosen, Susan M, Oswald, Brandon M, Longo, Joseph, Roy, Dominic G, Verway, Mark J, Johnson, Radia M, Samborska, Bozena, Duimstra, Lauren R, Scullion, Catherine A, Steadman, Mya, Vos, Matthew, Roddy, Thomas P, Krawczyk, Connie M, Williams, Kelsey S, Sheldon, Ryan D, Jones, Russell G

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13 C metabolite tracing reveals glutamine and acetate as critical in vivo fuels for CD8 T cells von Ma, Eric H, Dahabieh, Michael S, DeCamp, Lisa M, Kaymak, Irem, Kitchen-Goosen, Susan M, Oswald, Brandon M, Longo, Joseph, Roy, Dominic G, Verway, Mark J, Johnson, Radia M, Samborska, Bozena, Duimstra, Lauren R, Scullion, Catherine A, Steadman, Mya, Vos, Matthew, Roddy, Thomas P, Krawczyk, Connie M, Williams, Kelsey S, Sheldon, Ryan D, Jones, Russell G

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Corrigendum: Innate control of actin nucleation determines two distinct migration behaviours in dendritic cells von Vargas, Pablo, Maiuri, Paolo, Bretou, Marine, Sáez, Pablo J, Pierobon, Paolo, Maurin, Mathieu, Chabaud, Mélanie, Lankar, Danielle, Obino, Dorian, Terriac, Emmanuel, Raab, Matthew, Thiam, Hawa-Racine, Brocker, Thomas, Kitchen-Goosen, Susan M, Alberts, Arthur S, Sunareni, Praveen, Xia, Sheng, Li, Rong, Voituriez, Raphael, Piel, Matthieu, Lennon-Duménil, Ana-Maria

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LKB1 controls inflammatory potential through CRTC2-dependent epigenetic remodeling von Compton, Shelby Elizabeth, DeCamp, Lisa M, Kitchen-Goosen, Susan M, Lau, Kin, Dahabieh, Michael S, Guak, Hannah, VanderArk, Alexandra, Vos, Matthew, Williams, Kelsey S, Shi, Xiaobing, Rothbart, Scott B, Krawczyk, Connie M, Jones, Russell G

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Abstract 3356: The EWS/FLI1 transcriptome is characterized by marked heterogeneity across Ewing sarcoma cell lines von Kitchen-Goosen, Susan M., Bowman, Megan J., Adams, Marie, Berger, Penny, Grohar, Patrick J.

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Abstract 2883: Mithramycin inhibits KDM6A (UTX) and SWI/SNF to induce apoptosis in malignant rhabdoid tumor von Chasse, Maggie H., Boguslawski, Elissa, Sorensen, Katie, Beddows, Ian, Rybski, Kristin, Madaj, Zachary, Kitchen-Goosen, Susan M., Grohar, Patrick J.

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Abstract A32: Therapeutically targeting PRC2 expression and dynamics in rhabdoid tumor von Chasse, Maggie H., Boguslawski, Elissa A., Sorensen, Katie M., Wernette, Courtney E., Goosen, Susan M., Grohar, Patrick J.

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