First-line doublet immunotherapy: Game changer or hype for patients with mesothelioma? von Douma, L.H., Baas, P., de Gooijer, C.J.

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Improved Brain Penetration and Antitumor Efficacy of Temozolomide by Inhibition of ABCB1 and ABCG2 von de Gooijer, Mark C., de Vries, Nienke A., Buckle, Tessa, Buil, Levi C.M., Beijnen, Jos H., Boogerd, Willem, van Tellingen, Olaf

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The impact of P‐glycoprotein and breast cancer resistance protein on the brain pharmacokinetics and pharmacodynamics of a panel of MEK inhibitors von de Gooijer, Mark C., Zhang, Ping, Weijer, Ruud, Buil, Levi C.M., Beijnen, Jos H., van Tellingen, Olaf

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PI3K-mTOR Pathway Inhibition Exhibits Efficacy Against High-grade Glioma in Clinically Relevant Mouse Models von Lin, Fan, de Gooijer, Mark C, Hanekamp, Diana, Chandrasekaran, Gayathri, Buil, Levi C M, Thota, Nishita, Sparidans, Rolf W, Beijnen, Jos H, Würdinger, Tom, van Tellingen, Olaf

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ABCB1, ABCG2, and PTEN Determine the Response of Glioblastoma to Temozolomide and ABT-888 Therapy von FAN LIN, DE GOOIJER, Mark C, ROIG, Eloy Moreno, BUIL, Levi C. M, CHRISTNER, Susan M, BEUMER, Jan H, WÜRDINGER, Thomas, BEIJNEN, Jos H, VAN TELLINGEN, Olaf

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Buparlisib is a brain penetrable pan-PI3K inhibitor von de Gooijer, Mark C., Zhang, Ping, Buil, Levi C. M., Çitirikkaya, Ceren H., Thota, Nishita, Beijnen, Jos H., van Tellingen, Olaf

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Overcoming the blood–brain tumor barrier for effective glioblastoma treatment von van Tellingen, O, Yetkin-Arik, B, de Gooijer, M.C, Wesseling, P, Wurdinger, T, de Vries, H.E

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Nivolumab and ipilimumab in the real-world setting in patients with mesothelioma von Dumoulin, D W, Douma, L H, Hofman, M M, van der Noort, V, Cornelissen, R, de Gooijer, C J, Burgers, J A, Aerts, J G J V

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Identification of a Druggable Pathway Controlling Glioblastoma Invasiveness von Pencheva, Nora, de Gooijer, Mark C., Vis, Daniel J., Wessels, Lodewyk F.A., Würdinger, Tom, van Tellingen, Olaf, Bernards, René

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P-glycoprotein and breast cancer resistance protein restrict the brain penetration of the CDK4/6 inhibitor palbociclib von de Gooijer, Mark C., Zhang, Ping, Thota, Nishita, Mayayo-Peralta, Isabel, Buil, Levi C. M., Beijnen, Jos H., van Tellingen, Olaf

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ATP-binding cassette transporters restrict drug delivery and efficacy against brain tumors even when blood-brain barrier integrity is lost von de Gooijer, Mark C., Kemper, E. Marleen, Buil, Levi C.M., Çitirikkaya, Ceren H., Buckle, Tessa, Beijnen, Jos H., van Tellingen, Olaf

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ATP-binding cassette transporter inhibitor potency and substrate drug affinity are critical determinants of successful drug delivery enhancement to the brain von Lentzas, Aristeidis, de Gooijer, Mark C, Zuidema, Stefanie, Meurs, Amber, Çitirikkaya, Ceren H, Venekamp, Nikkie, Beijnen, Jos H, van Tellingen, Olaf

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Glycosylated extracellular vesicles released by glioblastoma cells are decorated by CCL18 allowing for cellular uptake via chemokine receptor CCR8 von Berenguer, Jordi, Lagerweij, Tonny, Zhao, Xi Wen, Dusoswa, Sophie, van der Stoop, Petra, Westerman, Bart, Gooijer, Mark C. de, Zoetemelk, Marloes, Zomer, Anoek, Crommentuijn, Matheus H. W., Wedekind, Laurine E., López-López, Àlan, Giovanazzi, Alberta, Bruch-Oms, Marina, Meulen-Muileman, Ida H. van der, Reijmers, Rogier M., van Kuppevelt, Toin H., García-Vallejo, Juan-Jesús, van Kooyk, Yvette, Tannous, Bakhos A., Wesseling, Pieter, Koppers-Lalic, Danijela, Vandertop, W. Peter, Noske, David P., van Beusechem, Victor W., van Rheenen, Jacco, Pegtel, D. Michiel, Tellingen, Olaf van, Wurdinger, Thomas

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The G2 checkpoint—a node‐based molecular switch von Gooijer, Mark C., Top, Arnout, Bockaj, Irena, Beijnen, Jos H., Würdinger, Thomas, Tellingen, Olaf

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Recycling drug screen repurposes hydroxyurea as a sensitizer of glioblastomas to temozolomide targeting de novo DNA synthesis, irrespective of molecular subtype von Teng, Jian, Hejazi, Seyedali, Hiddingh, Lotte, Carvalho, Litia, de Gooijer, Mark C, Wakimoto, Hiroaki, Barazas, Marco, Tannous, Marie, Chi, Andrew S, Noske, David P, Wesseling, Pieter, Wurdinger, Thomas, Batchelor, Tracy T, Tannous, Bakhos A

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An Experimenter’s Guide to Glioblastoma Invasion Pathways von de Gooijer, Mark C., Guillén Navarro, Miriam, Bernards, Rene, Wurdinger, Thomas, van Tellingen, Olaf

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ATP-binding cassette transporters limit the brain penetration of Wee1 inhibitors von de Gooijer, Mark C., Buil, Levi C. M., Beijnen, Jos H., van Tellingen, Olaf

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Trastuzumab-Emtansine and Osimertinib Combination Therapy to Target HER2 Bypass Track Resistance in EGFR Mutation-Positive NSCLC von Jebbink, M., de Langen, A.J., Monkhorst, K., Boelens, M.C., van den Broek, D., van der Noort, V., de Gooijer, C.J., Mahn, M., van der Wekken, A.J., Hendriks, L., Hashemi, S.M.S., Paats, M.S., Dingemans, A.C., Smit, E.F.

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Tryptophan depletion results in tryptophan-to-phenylalanine substitutants von Pataskar, Abhijeet, Champagne, Julien, Nagel, Remco, Kenski, Juliana, Laos, Maarja, Michaux, Justine, Pak, Hui Song, Bleijerveld, Onno B., Mordente, Kelly, Navarro, Jasmine Montenegro, Blommaert, Naomi, Nielsen, Morten M., Lovecchio, Domenica, Stone, Everett, Georgiou, George, de Gooijer, Mark C., van Tellingen, Olaf, Altelaar, Maarten, Joosten, Robbie P., Perrakis, Anastassis, Olweus, Johanna, Bassani-Sternberg, Michal, Peeper, Daniel S., Agami, Reuven

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Protocol for live-cell imaging during Tumor Treating Fields treatment with Inovitro Live von Slangen, Paul L.G., Porat, Yaara, Mertz, Marjolijn, van den Broek, Bram, Jalink, Kees, de Gooijer, Mark C., van Tellingen, Olaf, Borst, Gerben R.

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