Cannabidiol increases gramicidin current in human embryonic kidney cells: An observational study von Ghovanloo, Mohammad-Reza, Goodchild, Samuel J, Ruben, Peter C

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Conformational photo-trapping in NaV1.5: Inferring local motions at the “inactivation gate” von Goodchild, Samuel J., Ahern, Christopher A.

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Inhibitory effects of cannabidiol on voltage-dependent sodium currents von Ghovanloo, Mohammad-Reza, Shuart, Noah Gregory, Mezeyova, Janette, Dean, Richard A., Ruben, Peter C., Goodchild, Samuel J.

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Sequence of Gating Charge Movement and Pore Gating in hERG Activation and Deactivation Pathways von Goodchild, Samuel J., Macdonald, Logan C., Fedida, David

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Cannabidiol inhibits the skeletal muscle Nav1.4 by blocking its pore and by altering membrane elasticity von Ghovanloo, Mohammad-Reza, Choudhury, Koushik, Bandaru, Tagore S, Fouda, Mohamed A, Rayani, Kaveh, Rusinova, Radda, Phaterpekar, Tejas, Nelkenbrecher, Karen, Watkins, Abeline R, Poburko, Damon, Thewalt, Jenifer, Andersen, Olaf S, Delemotte, Lucie, Goodchild, Samuel J, Ruben, Peter C

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Selective NaV1.7 Antagonists with Long Residence Time Show Improved Efficacy against Inflammatory and Neuropathic Pain von Bankar, Girish, Goodchild, Samuel J., Howard, Sarah, Nelkenbrecher, Karen, Waldbrook, Matthew, Dourado, Michelle, Shuart, Noah G., Lin, Sophia, Young, Clint, Xie, Zhiwei, Khakh, Kuldip, Chang, Elaine, Sojo, Luis E., Lindgren, Andrea, Chowdhury, Sultan, Decker, Shannon, Grimwood, Michael, Andrez, Jean-Christophe, Dehnhardt, Christoph M., Pang, Jodie, Chang, Jae H., Safina, Brian S., Sutherlin, Daniel P., Johnson, James P., Hackos, David H., Robinette, C. Lee, Cohen, Charles J.

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Local anesthetic inhibition of a bacterial sodium channel von Lee, Sora, Goodchild, Samuel J, Ahern, Christopher A

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Non-psychotropic phytocannabinoid interactions with voltage-gated sodium channels: An update on cannabidiol and cannabigerol von Ghovanloo, Mohammad-Reza, Dib-Hajj, Sulayman D, Goodchild, Samuel J, Ruben, Peter C, Waxman, Stephen G

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Pharmacological determination of the fractional block of Nav channels required to impair neuronal excitability and ex vivo seizures von Thouta, Samrat, Waldbrook, Matthew G, Lin, Sophia, Mahadevan, Arjun, Mezeyova, Janette, Soriano, Maegan, Versi, Pareesa, Goodchild, Samuel J, Parrish, R Ryley

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The contribution of Na V 1.6 to the efficacy of voltage-gated sodium channel inhibitors in wild type and Na V 1.6 gain-of-function (GOF) mouse seizure control von Johnson, Jr, James P, Focken, Thilo, Karimi Tari, Parisa, Dube, Celine, Goodchild, Samuel J, Andrez, Jean-Christophe, Bankar, Girish, Burford, Kristen, Chang, Elaine, Chowdhury, Sultan, Christabel, Jessica, Dean, Richard, de Boer, Gina, Dehnhardt, Christoph, Gong, Wei, Grimwood, Michael, Hussainkhel, Angela, Jia, Qi, Khakh, Kuldip, Lee, Stephanie, Li, Jenny, Lin, Sophia, Lindgren, Andrea, Lofstrand, Verner, Mezeyova, Janette, Nelkenbrecher, Karen, Shuart, Noah Gregory, Sojo, Luis, Sun, Shaoyi, Waldbrook, Matthew, Wesolowski, Steven, Wilson, Michael, Xie, Zhiwei, Zenova, Alla, Zhang, Wei, Scott, Fiona L, Cutts, Alison J, Sherrington, Robin P, Winquist, Raymond, Cohen, Charles J, Empfield, James R

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Expanding the genotype-phenotype spectrum in SCN8A-related disorders von Hebbar, Malavika, Al-Taweel, Nawaf, Gill, Inderpal, Boelman, Cyrus, Dean, Richard A, Goodchild, Samuel J, Mezeyova, Janette, Shuart, Noah Gregory, Johnson, Jr, J P, Lee, James, Michoulas, Aspasia, Huh, Linda L, Armstrong, Linlea, Connolly, Mary B, Demos, Michelle K

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Allosteric Block of KCa2 Channels by Apamin von Lamy, Cédric, Goodchild, Samuel J., Weatherall, Kate L., Jane, David E., Liégeois, Jean-François, Seutin, Vincent, Marrion, Neil V.

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The contribution of NaV1.6 to the efficacy of voltage‐gated sodium channel inhibitors in wild type and NaV1.6 gain‐of‐function (GOF) mouse seizure control von Johnson, James P., Focken, Thilo, Karimi Tari, Parisa, Dube, Celine, Goodchild, Samuel J., Andrez, Jean‐Christophe, Bankar, Girish, Burford, Kristen, Chang, Elaine, Chowdhury, Sultan, Christabel, Jessica, Dean, Richard, Boer, Gina, Dehnhardt, Christoph, Gong, Wei, Grimwood, Michael, Hussainkhel, Angela, Jia, Qi, Khakh, Kuldip, Lee, Stephanie, Li, Jenny, Lin, Sophia, Lindgren, Andrea, Lofstrand, Verner, Mezeyova, Janette, Nelkenbrecher, Karen, Shuart, Noah Gregory, Sojo, Luis, Sun, Shaoyi, Waldbrook, Matthew, Wesolowski, Steven, Wilson, Michael, Xie, Zhiwei, Zenova, Alla, Zhang, Wei, Scott, Fiona L., Cutts, Alison J., Sherrington, Robin P., Winquist, Raymond, Cohen, Charles J., Empfield, James R.

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Identification of CNS-Penetrant Aryl Sulfonamides as Isoform-Selective NaV1.6 Inhibitors with Efficacy in Mouse Models of Epilepsy von Focken, Thilo, Burford, Kristen, Grimwood, Michael E, Zenova, Alla, Andrez, Jean-Christophe, Gong, Wei, Wilson, Michael, Taron, Matt, Decker, Shannon, Lofstrand, Verner, Chowdhury, Sultan, Shuart, Noah, Lin, Sophia, Goodchild, Samuel J, Young, Clint, Soriano, Maegan, Tari, Parisa K, Waldbrook, Matthew, Nelkenbrecher, Karen, Kwan, Rainbow, Lindgren, Andrea, de Boer, Gina, Lee, Stephanie, Sojo, Luis, DeVita, Robert J, Cohen, Charles J, Wesolowski, Steven S, Johnson, J. P, Dehnhardt, Christoph M, Empfield, James R

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Molecular Pharmacology of Selective NaV1.6 and Dual NaV1.6/NaV1.2 Channel Inhibitors that Suppress Excitatory Neuronal Activity Ex Vivo von Goodchild, Samuel J., Shuart, Noah Gregory, Williams, Aaron D., Ye, Wenlei, Parrish, R. Ryley, Soriano, Maegan, Thouta, Samrat, Mezeyova, Janette, Waldbrook, Matthew, Dean, Richard, Focken, Thilo, Ghovanloo, Mohammad-Reza, Ruben, Peter C., Scott, Fiona, Cohen, Charles J., Empfield, James, Johnson, JP

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Small conductance calcium-activated potassium channels: from structure to function von Weatherall, Kate L, Goodchild, Samuel J, Jane, David E, Marrion, Neil V

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Identification of aryl sulfonamides as novel and potent inhibitors of NaV1.5 von Sun, Shaoyi, Jia, Qi, Zenova, Alla Y., Lin, Sophia, Hussainkhel, Angela, Mezeyova, Janette, Chang, Elaine, Goodchild, Samuel J., Xie, Zhiwei, Lindgren, Andrea, de Boer, Gina, Kwan, Rainbow, Khakh, Kuldip, Sojo, Luis, Bichler, Paul, Johnson, J.P., Empfield, James R., Cohen, Charles J., Dehnhardt, Christoph M., Dean, Richard

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Molecular Pharmacology of Selective Na V 1.6 and Dual Na V 1.6/Na V 1.2 Channel Inhibitors that Suppress Excitatory Neuronal Activity Ex Vivo von Goodchild, Samuel J, Shuart, Noah Gregory, Williams, Aaron D, Ye, Wenlei, Parrish, R Ryley, Soriano, Maegan, Thouta, Samrat, Mezeyova, Janette, Waldbrook, Matthew, Dean, Richard, Focken, Thilo, Ghovanloo, Mohammad-Reza, Ruben, Peter C, Scott, Fiona, Cohen, Charles J, Empfield, James, Johnson, J P

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Design of Conformationally Constrained Acyl Sulfonamide Isosteres: Identification of N-([1,2,4]Triazolo[4,3- a]pyridin-3-yl)methane-sulfonamides as Potent and Selective hNa V 1.7 I... von Focken, Thilo, Chowdhury, Sultan, Zenova, Alla, Grimwood, Michael E, Chabot, Christine, Sheng, Tao, Hemeon, Ivan, Decker, Shannon M, Wilson, Michael, Bichler, Paul, Jia, Qi, Sun, Shaoyi, Young, Clint, Lin, Sophia, Goodchild, Samuel J, Shuart, Noah G, Chang, Elaine, Xie, Zhiwei, Li, Bowen, Khakh, Kuldip, Bankar, Girish, Waldbrook, Matthew, Kwan, Rainbow, Nelkenbrecher, Karen, Karimi Tari, Parisa, Chahal, Navjot, Sojo, Luis, Robinette, C Lee, White, Andrew D, Chen, Chien-An, Zhang, Yi, Pang, Jodie, Chang, Jae H, Hackos, David H, Johnson, Jr, J P, Cohen, Charles J, Ortwine, Daniel F, Sutherlin, Daniel P, Dehnhardt, Christoph M, Safina, Brian S

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Components of gating charge movement and S4 voltage-sensor exposure during activation of hERG channels von Wang, Zhuren, Dou, Ying, Goodchild, Samuel J, Es-Salah-Lamoureux, Zeineb, Fedida, David

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