Preclinical evaluation of AT-527, a novel guanosine nucleotide prodrug with potent, pan-genotypic activity against hepatitis C virus von Good, Steven S., Moussa, Adel, Zhou, Xiao-Jian, Pietropaolo, Keith, Sommadossi, Jean-Pierre

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AT-752, a double prodrug of a guanosine nucleotide analog, inhibits yellow fever virus in a hamster model von Lin, Kai, Good, Steven S, Julander, Justin G, Weight, Abbie E, Moussa, Adel, Sommadossi, Jean-Pierre

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A dual mechanism of action of AT-527 against SARS-CoV-2 polymerase von Shannon, Ashleigh, Fattorini, Véronique, Sama, Bhawna, Selisko, Barbara, Feracci, Mikael, Falcou, Camille, Gauffre, Pierre, El Kazzi, Priscila, Delpal, Adrien, Decroly, Etienne, Alvarez, Karine, Eydoux, Cécilia, Guillemot, Jean-Claude, Moussa, Adel, Good, Steven S., La Colla, Paolo, Lin, Kai, Sommadossi, Jean-Pierre, Zhu, Yingxiao, Yan, Xiaodong, Shi, Hui, Ferron, François, Canard, Bruno

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AT-527, a Double Prodrug of a Guanosine Nucleotide Analog, Is a Potent Inhibitor of SARS-CoV-2 In Vitro and a Promising Oral Antiviral for Treatment of COVID-19 von Good, Steven S., Westover, Jonna, Jung, Kie Hoon, Zhou, Xiao-Jian, Moussa, Adel, La Colla, Paolo, Collu, Gabriella, Canard, Bruno, Sommadossi, Jean-Pierre

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Potent and Selective Inhibition of Human Cytomegalovirus Replication by 1263W94, a Benzimidazole l-Riboside with a Unique Mode of Action von BIRON, Karen K, HARVEY, Robert J, STANAT, Sylvia C, DRACH, John C, TOWNSEND, Leroy B, KOSZALKA, George W, CHAMBERLAIN, Stanley C, GOOD, Steven S, SMITH, Albert A, DAVIS, Michelle G, TALARICO, Christine L, MILLER, Wayne H, FERRIS, Robert, DORNSIFE, Ronna E

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Evaluation of AT-752, a Double Prodrug of a Guanosine Nucleotide Analog with In Vitro and In Vivo Activity against Dengue and Other Flaviviruses von Good, Steven S., Shannon, Ashleigh, Lin, Kai, Moussa, Adel, Julander, Justin G., La Colla, Paolo, Collu, Gabriella, Canard, Bruno, Sommadossi, Jean-Pierre

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Safety, Pharmacokinetics, and Antiviral Activity of AT-527, a Novel Purine Nucleotide Prodrug, in Hepatitis C Virus-Infected Subjects with or without Cirrhosis von Berliba, Elina, Bogus, Maxim, Vanhoutte, Frédéric, Berghmans, Pieter-Jan, Good, Steven S, Moussa, Adel, Pietropaolo, Keith, Murphy, Robert L, Zhou, Xiao-Jian, Sommadossi, Jean-Pierre

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Estimation of Human Drug Clearance Using Multiexponential Techniques von Goteti, Kosalaram, Brassil, Patrick J., Good, Steven S., Garner, C. Edwin

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Preclinical and Toxicology Studies of 1263W94, a Potent and Selective Inhibitor of Human Cytomegalovirus Replication von KOSZALKA, George W, JOHNSON, Nelson W, GOOD, Steven S, BOYD, Leslie, CHAMBERLAIN, Stanley C, TOWNSEND, Leroy B, DRACH, John C, BIRON, Karen K

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Pharmacokinetics of IDX184, a liver-targeted oral prodrug of 2′-methylguanosine-5′-monophosphate, in the monkey and formulation optimization for human exposure von Pan-Zhou, Xin-Ru, Mayes, Benjamin A., Rashidzadeh, Hassan, Gasparac, Rahela, Smith, Steven, Bhadresa, Sanjeev, Gupta, Kusum, Cohen, Marita Larsson, Bu, Charlie, Good, Steven S., Moussa, Adel, Rush, Roger

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Metabolism of 5-Fluorocytosine to 5-Fluorouracil in Human Colorectal Tumor Cells Transduced with the Cytosine Deaminase Gene: Significant Antitumor Effects when Only a Small Percen... von Huber, Brian E., Austin, Elizabeth A., Richards, Cynthia A., Davis, Stephen T., Good, Steven S.

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In vivo antitumor activity of 5-fluorocytosine on human colorectal carcinoma cells genetically modified to express cytosine deaminase von HUBER, B. E, AUSTIN, E. A, GOOD, S. S, KNICK, V. C, TIBBELS, S, RICHARDS, D. A

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1265. AT-527, an Oral Purine Nucleotide Prodrug Exhibiting Potent In Vitro Antiviral Activity Against Human Coronaviruses, Including SARS-CoV-2 von Good, Steven S, Moussa, Adel, Zhou, Xiao-Jian, Pietropaolo, Keith, Sommadossi, Jean-Pierre

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169. AT-752, an Oral Guanosine Nucleotide Prodrug, Exhibits Potent in Vitro Activity Against Flaviviruses and Prevents Disease Progression in a Dengue Mouse Model von Good, Steven S, Moussa, Adel, Zhou, Xiao-Jian, Sommadossi, Jean-Pierre, Pietropaolo, Keith

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Safety, pharmacokinetics and antiviral activity of AT-527, a novel purine nucleotide prodrug, in HCV-infected subjects with and without cirrhosis von Berliba, Elina, Bogus, Maxim, Vanhoutte, Frédéric, Berghmans, Pieter-Jan, Good, Steven S, Moussa, Adel, Pietropaolo, Keith, Murphy, Robert L, Zhou, Xiao-Jian, Sommadossi, Jean-Pierre

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1592U89, a novel carbocyclic nucleoside analog with potent, selective anti-human immunodeficiency virus activity von DALUGE, S. M, GOOD, S. S, AVERETT, D. R, KRENITSKY, T. A, FALETTO, M. B, MILLER, W. H, CLAIR, M. H. S, BOONE, L. R, TISDALE, M, PARRY, N. R, REARDON, J. E, DORNSIFE, R. E

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Unique intracellular activation of the potent anti-human immunodeficiency virus agent 1592U89 von FALETTO, M. B, MILLER, W. H, GARVEY, E. P, CLAIR, M. H. S, DALUGE, S. M, GOOD, S. S

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Simultaneous quantification of zidovudine and its glucuronide in serum by high-performance liquid chromatography von Good, Steven S., Reynolds, David J., De Miranda, Paulo

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A novel, orally-active inidbitor of ICAM-1 and eselectin is efficacious in the treatment of colitis in rhesus macaques von Jurgensen, Cynthia H., Daluge, Susan M., Selph, Jeffrey L., Good, Steven S., Marr, Harry, Iannone, Marie A., Huber, Brian E., Mangel, Allen W., Lerche, Nicholas W., Washington, Kay, Wolberg, Gerald

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Synthesis and biological evaluation of dinucleoside methylphosphonates of 3′-azido-3′-deoxythymidine and 2′, 3′-dideoxycytidine von Puech, Frédéric, Gosselin, Gilles, Balzarini, Jan, Good, Steven S., Rideout, Janet L., De Clercq, Erik, Imbach, Jean-Louis

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