Breast cancers utilize hypoxic glycogen stores via PYGB, the brain isoform of glycogen phosphorylase, to promote metastatic phenotypes von Altemus, Megan A, Goo, Laura E, Little, Andrew C, Yates, Joel A, Cheriyan, Hannah G, Wu, Zhi Fen, Merajver, Sofia D

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IL-4/IL-13 Stimulated Macrophages Enhance Breast Cancer Invasion Via Rho-GTPase Regulation of Synergistic VEGF/CCL-18 Signaling von Little, Andrew C, Pathanjeli, Pragathi, Wu, Zhifen, Bao, Liwei, Goo, Laura E, Yates, Joel A, Oliver, C Ryan, Soellner, Matthew B, Merajver, Sofia D

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Abstract 1444: RhoC regulation of inflammatory breast cancer metabolism von Goo, Laura E., Yates, Joel A., Bao, Liwei, Wu, Zhifen, Merajver, Sofia D.

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Abstract 4363: Effects of the small GTPase RhoC on inflammatory breast cancer metabolism von Goo, Laura E., Yates, Joel A., Little, Andrew C., Kremer, Daniel, Kovalenko, Ilya, Oliver, Christopher R., Westerhof, Trisha, Wu, Zhifen, Vandecan, Nathalie, Bao, Liwei, Ulintz, Peter J., Lyssiotis, Costas A., Merajver, Sofia D.

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Analysis of 6,515 exomes reveals the recent origin of most human protein-coding variants von Fu, Wenqing, O’Connor, Timothy D., Jun, Goo, Kang, Hyun Min, Abecasis, Goncalo, Leal, Suzanne M., Gabriel, Stacey, Rieder, Mark J., Altshuler, David, Shendure, Jay, Nickerson, Deborah A., Bamshad, Michael J., NHLBI Exome Sequencing Project, Akey, Joshua M.

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Defining the impact of flavivirus envelope protein glycosylation site mutations on sensitivity to broadly neutralizing antibodies von Contreras, Maya, Stuart, Jackson B, Levoir, Lisa M, Belmont, Laura, Goo, Leslie

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An integrated map of structural variation in 2,504 human genomes von Sudmant, Peter H., Rausch, Tobias, Gardner, Eugene J., Handsaker, Robert E., Abyzov, Alexej, Huddleston, John, Zhang, Yan, Ye, Kai, Jun, Goo, Hsi-Yang Fritz, Markus, Konkel, Miriam K., Malhotra, Ankit, Stütz, Adrian M., Shi, Xinghua, Paolo Casale, Francesco, Chen, Jieming, Hormozdiari, Fereydoun, Dayama, Gargi, Chen, Ken, Malig, Maika, Chaisson, Mark J. P., Walter, Klaudia, Meiers, Sascha, Kashin, Seva, Garrison, Erik, Auton, Adam, Lam, Hugo Y. K., Jasmine Mu, Xinmeng, Alkan, Can, Antaki, Danny, Bae, Taejeong, Cerveira, Eliza, Chines, Peter, Chong, Zechen, Clarke, Laura, Dal, Elif, Ding, Li, Emery, Sarah, Fan, Xian, Gujral, Madhusudan, Kahveci, Fatma, Kidd, Jeffrey M., Kong, Yu, Lameijer, Eric-Wubbo, McCarthy, Shane, Flicek, Paul, Gibbs, Richard A., Marth, Gabor, Mason, Christopher E., Menelaou, Androniki, Muzny, Donna M., Nelson, Bradley J., Noor, Amina, Parrish, Nicholas F., Pendleton, Matthew, Quitadamo, Andrew, Raeder, Benjamin, Schadt, Eric E., Romanovitch, Mallory, Schlattl, Andreas, Sebra, Robert, Shabalin, Andrey A., Untergasser, Andreas, Walker, Jerilyn A., Wang, Min, Yu, Fuli, Zhang, Chengsheng, Zhang, Jing, Zheng-Bradley, Xiangqun, Zhou, Wanding, Zichner, Thomas, Sebat, Jonathan, Batzer, Mark A., McCarroll, Steven A., Mills, Ryan E., Gerstein, Mark B., Bashir, Ali, Stegle, Oliver, Devine, Scott E., Lee, Charles, Eichler, Evan E., Korbel, Jan O.

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Exome sequencing identifies rare LDLR and APOA5 alleles conferring risk for myocardial infarction von Do, Ron, Stitziel, Nathan O., Won, Hong-Hee, Jørgensen, Anders Berg, Duga, Stefano, Angelica Merlini, Pier, Kiezun, Adam, Farrall, Martin, Goel, Anuj, Zuk, Or, Guella, Illaria, Asselta, Rosanna, Lange, Leslie A., Peloso, Gina M., Auer, Paul L., Girelli, Domenico, Martinelli, Nicola, Farlow, Deborah N., DePristo, Mark A., Roberts, Robert, Stewart, Alexander F. R., Saleheen, Danish, Danesh, John, Epstein, Stephen E., Sivapalaratnam, Suthesh, Kees Hovingh, G., Kastelein, John J., Samani, Nilesh J., Schunkert, Heribert, Erdmann, Jeanette, Shah, Svati H., Kraus, William E., Davies, Robert, Nikpay, Majid, Johansen, Christopher T., Wang, Jian, Hegele, Robert A., Hechter, Eliana, Marz, Winfried, Kleber, Marcus E., Huang, Jie, Johnson, Andrew D., Li, Mingyao, Burke, Greg L., Gross, Myron, Liu, Yongmei, Assimes, Themistocles L., Heiss, Gerardo, Lange, Ethan M., Folsom, Aaron R., Taylor, Herman A., Olivieri, Oliviero, Hamsten, Anders, Clarke, Robert, Reilly, Dermot F., Yin, Wu, Rivas, Manuel A., Donnelly, Peter, Rossouw, Jacques E., Psaty, Bruce M., Herrington, David M., Wilson, James G., Rich, Stephen S., Bamshad, Michael J., Tracy, Russell P., Adrienne Cupples, L., Rader, Daniel J., Reilly, Muredach P., Spertus, John A., Cresci, Sharon, Hartiala, Jaana, Wilson Tang, W. H., Hazen, Stanley L., Allayee, Hooman, Reiner, Alex P., Carlson, Christopher S., Kooperberg, Charles, Jackson, Rebecca D., Boerwinkle, Eric, Lander, Eric S., Schwartz, Stephen M., Siscovick, David S., McPherson, Ruth, Tybjaerg-Hansen, Anne, Abecasis, Goncalo R., Watkins, Hugh, Nickerson, Deborah A., Ardissino, Diego, Sunyaev, Shamil R., O'Donnell, Christopher J., Altshuler, David, Gabriel, Stacey, Kathiresan, Sekar

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Multi-platform discovery of haplotype-resolved structural variation in human genomes von Chaisson, Mark J. P., Sanders, Ashley D., Zhao, Xuefang, Malhotra, Ankit, Porubsky, David, Rausch, Tobias, Gardner, Eugene J., Rodriguez, Oscar L., Guo, Li, Collins, Ryan L., Fan, Xian, Wen, Jia, Handsaker, Robert E., Fairley, Susan, Kronenberg, Zev N., Kong, Xiangmeng, Hormozdiari, Fereydoun, Lee, Dillon, Wenger, Aaron M., Hastie, Alex R., Antaki, Danny, Anantharaman, Thomas, Audano, Peter A., Brand, Harrison, Cantsilieris, Stuart, Cao, Han, Cerveira, Eliza, Chen, Chong, Chen, Xintong, Chin, Chen-Shan, Chong, Zechen, Chuang, Nelson T., Lambert, Christine C., Church, Deanna M., Clarke, Laura, Farrell, Andrew, Flores, Joey, Galeev, Timur, Gorkin, David U., Gujral, Madhusudan, Guryev, Victor, Heaton, William Haynes, Korlach, Jonas, Kumar, Sushant, Kwon, Jee Young, Lam, Ernest T., Lee, Jong Eun, Lee, Joyce, Lee, Wan-Ping, Lee, Sau Peng, Li, Shantao, Marks, Patrick, Viaud-Martinez, Karine, Meiers, Sascha, Munson, Katherine M., Navarro, Fabio C. P., Nelson, Bradley J., Nodzak, Conor, Noor, Amina, Kyriazopoulou-Panagiotopoulou, Sofia, Pang, Andy W. C., Qiu, Yunjiang, Rosanio, Gabriel, Ryan, Mallory, Stütz, Adrian, Spierings, Diana C. J., Ward, Alistair, Welch, AnneMarie E., Xiao, Ming, Xu, Wei, Zhang, Chengsheng, Zhu, Qihui, Zheng-Bradley, Xiangqun, Lowy, Ernesto, Yakneen, Sergei, McCarroll, Steven, Jun, Goo, Ding, Li, Koh, Chong Lek, Ren, Bing, Flicek, Paul, Chen, Ken, Gerstein, Mark B., Kwok, Pui-Yan, Lansdorp, Peter M., Marth, Gabor T., Sebat, Jonathan, Shi, Xinghua, Bashir, Ali, Ye, Kai, Devine, Scott E., Talkowski, Michael E., Mills, Ryan E., Marschall, Tobias, Korbel, Jan O., Eichler, Evan E., Lee, Charles

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Mapping and characterization of structural variation in 17,795 human genomes von Abel, Haley J., Larson, David E., Regier, Allison A., Chiang, Colby, Das, Indraniel, Kanchi, Krishna L., Layer, Ryan M., Neale, Benjamin M., Salerno, William J., Reeves, Catherine, Buyske, Steven, Matise, Tara C., Muzny, Donna M., Zody, Michael C., Lander, Eric S., Dutcher, Susan K., Stitziel, Nathan O., Hall, Ira M.

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X‐linked genetic associations in sporadic thoracic aortic dissection von Musfee, Fadi I., Jun, Goo, Mitchell, Laura E., Chen, Han, Guo, Dongchuan, Prakash, Siddharth K., Adkar, Shaunak Sanjay, Grove, Megan L., Choi, Ryan Bohyun, Klarin, Derek, Boerwinkle, Eric, Milewicz, Dianna M.

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Single B cell transcriptomics identifies multiple isotypes of broadly neutralizing antibodies against flaviviruses von Lubow, Jay, Levoir, Lisa M, Ralph, Duncan K, Belmont, Laura, Contreras, Maya, Cartwright-Acar, Catiana H, Kikawa, Caroline, Kannan, Shruthi, Davidson, Edgar, Duran, Veronica, Rebellon-Sanchez, David E, Sanz, Ana M, Rosso, Fernando, Doranz, Benjamin J, Einav, Shirit, Matsen Iv, Frederick A, Goo, Leslie

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Abstract 10884: X-Linked Genetic Associations in Sporadic Thoracic Aortic Aneurysm and Dissection von Musfee, Fadi I, Jun, Goo, Mitchell, Laura E, Chen, Han, Guo, Dongchuan, Grove, Megan L, Boerwinkle, Eric, Milewicz, Dianna M

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Integrating sequence and array data to create an improved 1000 Genomes Project haplotype reference panel von Delaneau, Olivier, Marchini, Jonathan

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Flares in IIMs and the timeline following COVID-19 vaccination: a combined analysis of the COVAD-1 and -2 surveys von R, Naveen, Sen, Parikshit, Griger, Zoltán, Day, Jessica, Joshi, Mrudula, Nune, Arvind, Nikiphorou, Elena, Saha, Sreoshy, Tan, Ai Lyn, Shinjo, Samuel Katsuyuki, Ziade, Nelly, Velikova, Tsvetelina, Milchert, Marcin, Jagtap, Kshitij, Parodis, Ioannis, Gracia-Ramos, Abraham Edgar, Cavagna, Lorenzo, Kuwana, Masataka, Knitza, Johannes, Chen, Yi Ming, Makol, Ashima, Agarwal, Vishwesh, Patel, Aarat, Pauling, John D, Wincup, Chris, Barman, Bhupen, Zamora Tehozol, Erick Adrian, Rojas Serrano, Jorge, García-De La Torre, Ignacio, Colunga-Pedraza, Iris J, Merayo-Chalico, Javier, Chibuzo, Okwara Celestine, Katchamart, Wanruchada, Akarawatcharangura Goo, Phonpen, Shumnalieva, Russka, Hoff, Leonardo Santos, El Kibbi, Lina, Halabi, Hussein, Vaidya, Binit, Shaharir, Syahrul Sazliyana, Hasan, A T M Tanveer, Dey, Dzifa, Toro Gutiérrez, Carlos Enrique, Caballero-Uribe, Carlo V, Lilleker, James B, Salim, Babur, Gheita, Tamer, Chatterjee, Tulika, Distler, Oliver, Saavedra, Miguel A, Chinoy, Hector, Agarwal, Vikas, Aggarwal, Rohit, Gupta, Latika

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Genome-wide association analysis of dementia and its clinical endophenotypes reveal novel loci associated with Alzheimer's disease and three causality networks: The GR@ACE project von de Rojas, Itziar, Hernández, Isabel, Alegret, Montserrat, Hernández-Olasagarre, Begoña, Madrid, Laura, Maroñas, Olalla, Rosende-Roca, Maitée, Mauleón, Ana, Lafuente, Asunción, Rodríguez-Gómez, Octavio, Pérez-Cordón, Alba, Preckler, Silvia, Ruiz, Susana, Aguilera, Nuria, Sotolongo-Grau, Oscar, Abdelnour, C., Aguilera, N., Buendia, M., Cañabate, P., Carracedo, A., Diego, S., Espinosa, A., Gailhajenet, A., González Pérez, A., Hernández, I., Ibarria, M., Macias, J., Martín, E., Montrreal, L., Moreno-Grau, S., Orellana, A., Pelejà, E., Preckler, S., Quintela, I., Rodríguez-Gómez, O., Rosende-Roca, M., Ruiz, S., Serrano-Rios, M., Sotolongo-Grau, O., Valero, S., Alarcón-Martín, E., Álvarez, V., Antequera, M., Antúnez, C., Baquero, M., Blesa, R., Boada, M., Buiza-Rueda, D., Bullido, M.J., Burguera, J.A., Calero, M., Carrillo, F., Carrión-Claro, M., Casajeros, M.J., Cruz-Gamero, J.M., de Pancorbo, M.M., Diez-Fairen, M., Fortea, J., Frank-García, A., García-Alberca, J.M., Garcia Madrona, S., Jesús, S., Lage, C., López de Munáin, A., López-García, S., Macias, D., Marín, M., Marín-Muñoz, J., Marquié, M., Martín Montes, A., Medina, M., Mendioroz Iriarte, M., Menéndez-González, M., Molinuevo, J.L., Monté-Rubio, G., Montrreal, L., Moreno-Grau, S., Piñol Ripoll, G., Rábano, A., Real de Asúa, D., Rodrigo, S., A, Ruiz, Sanchez del Valle Díaz, R., Sánchez-Juan, P., Tárraga, L., Marquié, Marta, Monté-Rubio, Gemma, Clarimón, Jordi, Pástor, Pau, Álvarez, Victoria, Franco, Emilio, Mir, Pablo, Calero, Miguel, Medina, Miguel, Rábano, Alberto, Antúnez, Carmen, Real, Luis Miguel, Orellana, Adelina, Sáez, María Eugenia, Boada, Mercè

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Prosaposin is a regulator of progranulin levels and oligomerization von Nicholson, Alexandra M., Finch, NiCole A., Almeida, Marcio, Perkerson, Ralph B., van Blitterswijk, Marka, Wojtas, Aleksandra, Cenik, Basar, Rotondo, Sergio, Inskeep, Venette, Almasy, Laura, Dyer, Thomas, Peralta, Juan, Jun, Goo, Wood, Andrew R., Frayling, Timothy M., Fuchsberger, Christian, Fowler, Sharon, Teslovich, Tanya M., Manning, Alisa K., Kumar, Satish, Curran, Joanne, Lehman, Donna, Abecasis, Goncalo, Duggirala, Ravindranath, Pottier, Cyril, Zahir, Haaris A., Crook, Julia E., Karydas, Anna, Mitic, Laura, Sun, Ying, Dickson, Dennis W., Bu, Guojun, Herz, Joachim, Yu, Gang, Miller, Bruce L., Ferguson, Shawn, Petersen, Ronald C., Graff-Radford, Neill, Blangero, John, Rademakers, Rosa

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TOP-LD: A tool to explore linkage disequilibrium with TOPMed whole-genome sequence data von Huang, Le, Rosen, Jonathan D., Sun, Quan, Chen, Jiawen, Wheeler, Marsha M., Zhou, Ying, Min, Yuan-I, Kooperberg, Charles, Conomos, Matthew P., Stilp, Adrienne M., Rich, Stephen S., Rotter, Jerome I., Manichaikul, Ani, Loos, Ruth J.F., Kenny, Eimear E., Blackwell, Thomas W., Smith, Albert V., Jun, Goo, Sedlazeck, Fritz J., Metcalf, Ginger, Boerwinkle, Eric, Raffield, Laura M., Reiner, Alex P., Auer, Paul L., Li, Yun

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Gene expression down-regulation in CD90+ prostate tumor-associated stromal cells involves potential organ-specific genes von Pascal, Laura E, Goo, Young Ah, Vêncio, Ricardo Zn, Page, Laura S, Chambers, Amber A, Liebeskind, Emily S, Takayama, Thomas K, True, Lawrence D, Liu, Alvin Y

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Human-specific tandem repeat expansion and differential gene expression during primate evolution von Sulovari, Arvis, Li, Ruiyang, Audano, Peter A., Porubsky, David, Vollger, Mitchell R., Logsdon, Glennis A., Warren, Wesley C., Pollen, Alex A., Chaisson, Mark J. P., Eichler, Evan E.

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