ecDNA hubs drive cooperative intermolecular oncogene expression von Hung, King L., Yost, Kathryn E., Xie, Liangqi, Shi, Quanming, Helmsauer, Konstantin, Luebeck, Jens, Schöpflin, Robert, Lange, Joshua T., Chamorro González, Rocío, Weiser, Natasha E., Chen, Celine, Valieva, Maria E., Wong, Ivy Tsz-Lo, Wu, Sihan, Dehkordi, Siavash R., Duffy, Connor V., Kraft, Katerina, Tang, Jun, Belk, Julia A., Rose, John C., Corces, M. Ryan, Granja, Jeffrey M., Li, Rui, Rajkumar, Utkrisht, Friedlein, Jordan, Bagchi, Anindya, Satpathy, Ansuman T., Tjian, Robert, Mundlos, Stefan, Bafna, Vineet, Henssen, Anton G., Mischel, Paul S., Liu, Zhe, Chang, Howard Y.

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Partner independent fusion gene detection by multiplexed CRISPR-Cas9 enrichment and long read nanopore sequencing von Stangl, Christina, de Blank, Sam, Renkens, Ivo, Westera, Liset, Verbeek, Tamara, Valle-Inclan, Jose Espejo, González, Rocio Chamorro, Henssen, Anton G., van Roosmalen, Markus J., Stam, Ronald W., Voest, Emile E., Kloosterman, Wigard P., van Haaften, Gijs, Monroe, Glen R.

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Extrachromosomal DNA amplifications in cancer von Yi, Eunhee, Chamorro González, Rocío, Henssen, Anton G., Verhaak, Roel G. W.

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Disentangling extrachromosomal circular DNA heterogeneity in single cells with scEC&T-seq

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Parallel sequencing of extrachromosomal circular DNAs and transcriptomes in single cancer cells von Chamorro González, Rocío, Conrad, Thomas, Stöber, Maja C., Xu, Robin, Giurgiu, Mădălina, Rodriguez-Fos, Elias, Kasack, Katharina, Brückner, Lotte, van Leen, Eric, Helmsauer, Konstantin, Dorado Garcia, Heathcliff, Stefanova, Maria E., Hung, King L., Bei, Yi, Schmelz, Karin, Lodrini, Marco, Mundlos, Stefan, Chang, Howard Y., Deubzer, Hedwig E., Sauer, Sascha, Eggert, Angelika, Schulte, Johannes H., Schwarz, Roland F., Haase, Kerstin, Koche, Richard P., Henssen, Anton G.

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Coordinated inheritance of extrachromosomal DNAs in cancer cells von Hung, King L., Jones, Matthew G., Wong, Ivy Tsz-Lo, Curtis, Ellis J., Lange, Joshua T., He, Britney Jiayu, Luebeck, Jens, Schmargon, Rachel, Scanu, Elisa, Brückner, Lotte, Yan, Xiaowei, Li, Rui, Gnanasekar, Aditi, Chamorro González, Rocío, Belk, Julia A., Liu, Zhonglin, Melillo, Bruno, Bafna, Vineet, Dörr, Jan R., Werner, Benjamin, Huang, Weini, Cravatt, Benjamin F., Henssen, Anton G., Mischel, Paul S., Chang, Howard Y.

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Intercellular extrachromosomal DNA copy-number heterogeneity drives neuroblastoma cell state diversity von Stöber, Maja C., Chamorro González, Rocío, Brückner, Lotte, Conrad, Thomas, Wittstruck, Nadine, Szymansky, Annabell, Eggert, Angelika, Schulte, Johannes H., Koche, Richard P., Henssen, Anton G., Schwarz, Roland F., Haase, Kerstin

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Targeted profiling of human extrachromosomal DNA by CRISPR-CATCH von Hung, King L., Luebeck, Jens, Dehkordi, Siavash R., Colón, Caterina I., Li, Rui, Wong, Ivy Tsz-Lo, Coruh, Ceyda, Dharanipragada, Prashanthi, Lomeli, Shirley H., Weiser, Natasha E., Moriceau, Gatien, Zhang, Xiao, Bailey, Chris, Houlahan, Kathleen E., Yang, Wenting, González, Rocío Chamorro, Swanton, Charles, Curtis, Christina, Jamal-Hanjani, Mariam, Henssen, Anton G., Law, Julie A., Greenleaf, William J., Lo, Roger S., Mischel, Paul S., Bafna, Vineet, Chang, Howard Y.

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Enhancer hijacking determines extrachromosomal circular MYCN amplicon architecture in neuroblastoma von Helmsauer, Konstantin, Valieva, Maria E., Ali, Salaheddine, Chamorro González, Rocío, Schöpflin, Robert, Röefzaad, Claudia, Bei, Yi, Dorado Garcia, Heathcliff, Rodriguez-Fos, Elias, Puiggròs, Montserrat, Kasack, Katharina, Haase, Kerstin, Keskeny, Csilla, Chen, Celine Y., Kuschel, Luis P., Euskirchen, Philipp, Heinrich, Verena, Robson, Michael I., Rosswog, Carolina, Toedling, Joern, Szymansky, Annabell, Hertwig, Falk, Fischer, Matthias, Torrents, David, Eggert, Angelika, Schulte, Johannes H., Mundlos, Stefan, Henssen, Anton G., Koche, Richard P.

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Abstract 1693: Dissecting intercellular extrachromosomal circular DNA heterogeneity in single cancer cells with scEC&T-seq von Gonzalez, Rocio Chamorro, Conrad, Thomas, Xu, Robin, Giurgiu, Madalina, Cwikla, Maja, Kasack, Katharina, Brückner, Lotte, van Leen, Eric, Rodriguez-Fos, Elias, Helmsauer, Konstantin, Garcia, Heathcliff Dorado, Bei, Yi, Schmelz, Karin, Sauer, Sascha, Eggert, Angelika, Schulte, Johannes H., Schwarz, Roland F., Haase, Kerstin, Koche, Richard P., Henssen, Anton G.

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Detection and Validation of Circular DNA Fragments Using Nanopore Sequencing von Tüns, Alicia Isabell, Hartmann, Till, Magin, Simon, González, Rocío Chamorro, Henssen, Anton George, Rahmann, Sven, Schramm, Alexander, Köster, Johannes

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Dissecting extrachromosomal circular DNA heterogeneity in single cells with scEC&T-seq von Chamorro Gonzalez, Maria del Rocio

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Elimusertib has anti-tumor activity in preclinical patient-derived pediatric solid tumor models von Pusch, Fabian F, Dorado Garcia, Heathcliff, Xu, Robin, Gürgen, Dennis, Bei, Yi, Brückner, Lotte, Röefzaad, Claudia, von Stebut, Jennifer, Bardinet, Victor, Chamorro Gonzalez, Rocío, Eggert, Angelika, Schulte, Johannes H, Hundsdörfer, Patrick, Seifert, Georg, Haase, Kerstin, Schäfer, Beat W, Wachtel, Marco, Kühl, Anja A, Ortiz, Michael V, Wengner, Antje M, Scheer, Monika, Henssen, Anton G

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Disentangling extrachromosomal circular DNA heterogeneity in single cells with scEC&T-seq von González, Rocío Chamorro, Henssen, Anton G

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Decoil: Reconstructing Extrachromosomal DNA Structural Heterogeneity from Long-Read Sequencing Data von Giurgiu, Mădălina, Wittstruck, Nadine, Rodriguez-Fos, Elias, González, Rocío Chamorro, Brückner, Lotte, Krienelke-Szymansky, Annabell, Helmsauer, Konstantin, Hartebrodt, Anne, Euskirchen, Philipp, Koche, Richard P., Haase, Kerstin, Reinert, Knut, Henssen, Anton G.

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Therapeutic targeting of ATR in alveolar rhabdomyosarcoma von Dorado García, Heathcliff, Pusch, Fabian, Bei, Yi, von Stebut, Jennifer, Ibáñez, Glorymar, Guillan, Kristina, Imami, Koshi, Gürgen, Dennis, Rolff, Jana, Helmsauer, Konstantin, Meyer-Liesener, Stephanie, Timme, Natalie, Bardinet, Victor, Chamorro González, Rocío, MacArthur, Ian C., Chen, Celine Y., Schulz, Joachim, Wengner, Antje M., Furth, Christian, Lala, Birgit, Eggert, Angelika, Seifert, Georg, Hundsoerfer, Patrick, Kirchner, Marieluise, Mertins, Philipp, Selbach, Matthias, Lissat, Andrej, Dubois, Frank, Horst, David, Schulte, Johannes H., Spuler, Simone, You, Daoqi, Dela Cruz, Filemon, Kung, Andrew L., Haase, Kerstin, DiVirgilio, Michela, Scheer, Monika, Ortiz, Michael V., Henssen, Anton G.

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Abstract 1667: Elimusertib shows stronger antitumor activity than standard of care chemotherapy in pediatric solid tumor models von Pusch, Fabian Fadi, García, Heathcliff Dorado, Xu, Robin, Guergen, Dennis, Bei, Yi, Brueckner, Lotte, Roeefzaad, Claudia, von Stebut, Jennifer, Bardinet, Victor, Gonzalez, María del Rocío Chamorro, Eggert, Angelika, Schulte, Johannes H., Hundsdoerfer, Patrick, Seifert, Georg, Haase, Kerstin, Schaefer, Beat, Wachtel, Marco, Kühl, Anja A., Ortiz, Michael, Wengner, Antje M., Scheer, Monika, Henssen, Anton G.

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Parallel sequencing of extrachromosomal circular DNAs and transcriptomes in single cancer cells von Chamorro González, Rocío, Conrad, Thomas, Stöber, Maja C, Xu, Robin, Giurgiu, Mădălina, Rodriguez-Fos, Elias, Kasack, Katharina, Brückner, Lotte, Leen, Eric van, Helmsauer, Konstantin, Dorado Garcia, Heathcliff, Stefanova, Maria E, Hung, King L, Bei, Yi, Schmelz, Karin, Lodrini, Marco, Mundlos, Stefan, Chang, Howard Y, Deubzer, Hedwig E, Sauer, Sascha, Eggert, Angelika, Schulte, Johannes H, Schwarz, Roland F, Haase, Kerstin, Koche, Richard P, Henssen, Anton G

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Targeted profiling of human extrachromosomal DNA by CRISPR-CATCH von Hung, King L, Luebeck, Jens, Dehkordi, Siavash R, Colón, Caterina I, Li, Rui, Wong, Ivy Tsz-Lo, Coruh, Ceyda, Dharanipragada, Prashanthi, Lomeli, Shirley H, Weiser, Natasha E, Moriceau, Gatien, Zhang, Xiao, Bailey, Chris, Houlahan, Kathleen E, Yang, Wenting, González, Rocío Chamorro, Swanton, Charles, Curtis, Christina, Jamal-Hanjani, Mariam, Henssen, Anton G, Law, Julie A, Greenleaf, William J, Lo, Roger S, Mischel, Paul S, Bafna, Vineet, Chang, Howard Y

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Targeted profiling of human extrachromosomal DNA by CRISPR-CATCH von Hung, King L, Luebeck, Jens, Dehkordi, Siavash R, Colón, Caterina I, Li, Rui, Wong, Ivy Tsz-Lo, Coruh, Ceyda, Dharanipragada, Prashanthi, Lomeli, Shirley H, Weiser, Natasha E, Moriceau, Gatien, Zhang, Xiao, Bailey, Chris, Houlahan, Kathleen E, Yang, Wenting, González, Rocío Chamorro, Swanton, Charles, Curtis, Christina, Jamal-Hanjani, Mariam, Henssen, Anton G, Law, Julie A, Greenleaf, William J, Lo, Roger S, Mischel, Paul S, Bafna, Vineet, Chang, Howard Y

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