Molecular Pathways: Targeting Cellular Energy Metabolism in Cancer via Inhibition of SLC2A1 and LDHA von Ooi, Aik T, Gomperts, Brigitte N

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SARS-CoV-2 infection rewires host cell metabolism and is potentially susceptible to mTORC1 inhibition von Mullen, Peter J., Garcia, Gustavo, Purkayastha, Arunima, Matulionis, Nedas, Schmid, Ernst W., Momcilovic, Milica, Sen, Chandani, Langerman, Justin, Ramaiah, Arunachalam, Shackelford, David B., Damoiseaux, Robert, French, Samuel W., Plath, Kathrin, Gomperts, Brigitte N., Arumugaswami, Vaithilingaraja, Christofk, Heather R.

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Dynamic Changes in Intracellular ROS Levels Regulate Airway Basal Stem Cell Homeostasis through Nrf2-Dependent Notch Signaling von Paul, Manash K., Bisht, Bharti, Darmawan, Daphne O., Chiou, Richard, Ha, Vi L., Wallace, William D., Chon, Andrew T., Hegab, Ahmed E., Grogan, Tristan, Elashoff, David A., Alva-Ornelas, Jackelyn A., Gomperts, Brigitte N.

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Wnt signaling in lung development, regeneration, and disease progression von Aros, Cody J., Pantoja, Carla J., Gomperts, Brigitte N.

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Pan-cancer Convergence to a Small-Cell Neuroendocrine Phenotype that Shares Susceptibilities with Hematological Malignancies von Balanis, Nikolas G., Sheu, Katherine M., Esedebe, Favour N., Patel, Saahil J., Smith, Bryan A., Park, Jung Wook, Alhani, Salwan, Gomperts, Brigitte N., Huang, Jiaoti, Witte, Owen N., Graeber, Thomas G.

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Induction of multiciliated cells from induced pluripotent stem cells von Gomperts, Brigitte N.

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SARS-CoV-2 infection of primary human lung epithelium for COVID-19 modeling and drug discovery von Mulay, Apoorva, Konda, Bindu, Garcia, Gustavo, Yao, Changfu, Beil, Stephen, Villalba, Jaquelyn M., Koziol, Colin, Sen, Chandani, Purkayastha, Arunima, Kolls, Jay. K., Pociask, Derek A., Pessina, Patrizia, de Aja, Julio Sainz, Garcia-de-Alba, Carolina, Kim, Carla F., Gomperts, Brigitte, Arumugaswami, Vaithilingaraja, Stripp, Barry R.

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Targeting PEA3 transcription factors to mitigate small cell lung cancer progression von Shia, David W., Choi, WooSuk, Vijayaraj, Preethi, Vuong, Valarie, Sandlin, Jenna M., Lu, Michelle M., Aziz, Adam, Marin, Caliope, Aros, Cody J., Sen, Chandani, Durra, Abdo, Lund, Andrew J., Purkayastha, Arunima, Rickabaugh, Tammy M., Graeber, Thomas G., Gomperts, Brigitte N.

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The role of CXC chemokines in pulmonary fibrosis von Strieter, Robert M, Gomperts, Brigitte N, Keane, Michael P

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Fibrocytes in lung disease von Gomperts, Brigitte N., Strieter, Robert M.

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Hippo signaling pathway activation during SARS-CoV-2 infection contributes to host antiviral response von Garcia, Jr, Gustavo, Jeyachandran, Arjit Vijey, Wang, Yijie, Irudayam, Joseph Ignatius, Cario, Sebastian Castillo, Sen, Chandani, Li, Shen, Li, Yunfeng, Kumar, Ashok, Nielsen-Saines, Karin, French, Samuel W, Shah, Priya S, Morizono, Kouki, Gomperts, Brigitte N, Deb, Arjun, Ramaiah, Arunachalam, Arumugaswami, Vaithilingaraja

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Direct Exposure to SARS-CoV-2 and Cigarette Smoke Increases Infection Severity and Alters the Stem Cell-Derived Airway Repair Response von Purkayastha, Arunima, Sen, Chandani, Garcia, Gustavo, Langerman, Justin, Shia, David W., Meneses, Luisa K., Vijayaraj, Preethi, Durra, Abdo, Koloff, Caroline R., Freund, Delilah R., Chi, Justin, Rickabaugh, Tammy M., Mulay, Apoorva, Konda, Bindu, Sim, Myung S., Stripp, Barry R., Plath, Kathrin, Arumugaswami, Vaithilingaraja, Gomperts, Brigitte N.

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Transcriptional analysis of cystic fibrosis airways at single-cell resolution reveals altered epithelial cell states and composition von Carraro, Gianni, Langerman, Justin, Sabri, Shan, Lorenzana, Zareeb, Purkayastha, Arunima, Zhang, Guangzhu, Konda, Bindu, Aros, Cody J., Calvert, Ben A., Szymaniak, Aleks, Wilson, Emily, Mulligan, Michael, Bhatt, Priyanka, Lu, Junjie, Vijayaraj, Preethi, Yao, Changfu, Shia, David W., Lund, Andrew J., Israely, Edo, Rickabaugh, Tammy M., Ernst, Jason, Mense, Martin, Randell, Scott H., Vladar, Eszter K., Ryan, Amy L., Plath, Kathrin, Mahoney, John E., Stripp, Barry R., Gomperts, Brigitte N.

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The aCCR(2)ual of M2 Macrophages Provides Some Breathing Room von Vijayaraj, Preethi, Gomperts, Brigitte N.

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Light-field tomographic fluorescence lifetime imaging microscopy von Ma, Yayao, Park, Jongchan, Huang, Luzhe, Sen, Chandani, Burri, Samuel, Bruschini, Claudio, Yang, Xilin, Cui, Qi, Cameron, Robert B, Fishbein, Gregory A, Gomperts, Brigitte N, Ozcan, Aydogan, Charbon, Edoardo, Gao, Liang

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Development of a Three‐Dimensional Bioengineering Technology to Generate Lung Tissue for Personalized Disease Modeling von Wilkinson, Dan C., Alva‐Ornelas, Jackelyn A., Sucre, Jennifer M.S., Vijayaraj, Preethi, Durra, Abdo, Richardson, Wade, Jonas, Steven J., Paul, Manash K., Karumbayaram, Saravanan, Dunn, Bruce, Gomperts, Brigitte N.

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Antiviral drug screen identifies DNA-damage response inhibitor as potent blocker of SARS-CoV-2 replication von Garcia, Gustavo, Sharma, Arun, Ramaiah, Arunachalam, Sen, Chandani, Purkayastha, Arunima, Kohn, Donald B., Parcells, Mark S., Beck, Sebastian, Kim, Heeyoung, Bakowski, Malina A., Kirkpatrick, Melanie G., Riva, Laura, Wolff, Karen C., Han, Brandon, Yuen, Constance, Ulmert, David, Purbey, Prabhat K., Scumpia, Philip, Beutler, Nathan, Rogers, Thomas F., Chatterjee, Arnab K., Gabriel, Gülsah, Bartenschlager, Ralf, Gomperts, Brigitte, Svendsen, Clive N., Betz, Ulrich A.K., Damoiseaux, Robert D., Arumugaswami, Vaithilingaraja

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Distinct Spatiotemporally Dynamic Wnt-Secreting Niches Regulate Proximal Airway Regeneration and Aging von Aros, Cody J., Vijayaraj, Preethi, Pantoja, Carla J., Bisht, Bharti, Meneses, Luisa K., Sandlin, Jenna M., Tse, Jonathan A., Chen, Michelle W., Purkayastha, Arunima, Shia, David W., Sucre, Jennifer M.S., Rickabaugh, Tammy M., Vladar, Eszter K., Paul, Manash K., Gomperts, Brigitte N.

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Development of a small cell lung cancer organoid model to study cellular interactions and survival after chemotherapy von Sen, Chandani, Koloff, Caroline R., Kundu, Souvik, Wilkinson, Dan C., Yang, Juliette M., Shia, David W., Meneses, Luisa K., Rickabaugh, Tammy M., Gomperts, Brigitte N.

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A three-dimensional human model of the fibroblast activation that accompanies bronchopulmonary dysplasia identifies Notch-mediated pathophysiology von Sucre, Jennifer M S, Wilkinson, Dan, Vijayaraj, Preethi, Paul, Manash, Dunn, Bruce, Alva-Ornelas, Jackelyn A, Gomperts, Brigitte N

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