Pathogen blockade of TAK1 triggers caspase-8-dependent cleavage of gasdermin D and cell death von Orning, Pontus, Weng, Dan, Starheim, Kristian, Ratner, Dmitry, Best, Zachary, Lee, Bettina, Brooks, Alexandria, Xia, Shiyu, Wu, Hao, Kelliher, Michelle A, Berger, Scott B, Gough, Peter J, Bertin, John, Proulx, Megan M, Goguen, Jon D, Kayagaki, Nobuhiko, Fitzgerald, Katherine A, Lien, Egil

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The NLRP12 Inflammasome Recognizes Yersinia pestis von Vladimer, Gregory I., Weng, Dan, Paquette, Sara W. Montminy, Vanaja, Sivapriya Kailasan, Rathinam, Vijay A.K., Aune, Marie Hjelmseth, Conlon, Joseph E., Burbage, Joseph J., Proulx, Megan K., Liu, Qin, Reed, George, Mecsas, Joan C., Iwakura, Yoichiro, Bertin, John, Goguen, Jon D., Fitzgerald, Katherine A., Lien, Egil

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The Yersinia pestis Effector YopM Inhibits Pyrin Inflammasome Activation von Ratner, Dmitry, Orning, M Pontus A, Proulx, Megan K, Wang, Donghai, Gavrilin, Mikhail A, Wewers, Mark D, Alnemri, Emad S, Johnson, Peter F, Lee, Bettina, Mecsas, Joan, Kayagaki, Nobuhiko, Goguen, Jon D, Lien, Egil

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Caspase-8 and RIP kinases regulate bacteria-induced innate immune responses and cell death von Weng, Dan, Marty-Roix, Robyn, Ganesan, Sandhya, Proulx, Megan K., Vladimer, Gregory I., Kaiser, William J., Mocarski, Edward S., Pouliot, Kimberly, Chan, Francis Ka-Ming, Kelliher, Michelle A., Harris, Phillip A., Bertin, John, Gough, Peter J., Shayakhmetov, Dmitry M., Goguen, Jon D., Fitzgerald, Katherine A., Silverman, Neal, Lien, Egil

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Nitric oxide prevents a pathogen-permissive granulocytic inflammation during tuberculosis von Mishra, Bibhuti B., Lovewell, Rustin R., Olive, Andrew J., Zhang, Guoliang, Wang, Wenfei, Eugenin, Eliseo, Smith, Clare M., Phuah, Jia Yao, Long, Jarukit E., Dubuke, Michelle L., Palace, Samantha G., Goguen, Jon D., Baker, Richard E., Nambi, Subhalaxmi, Mishra, Rabinarayan, Booty, Matthew G., Baer, Christina E., Shaffer, Scott A., Dartois, Veronique, McCormick, Beth A., Chen, Xinchun, Sassetti, Christopher M.

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Virulence factors of Yersinia pestis are overcome by a strong lipopolysaccharide response von Lien, Egil, Montminy, Sara W, Khan, Naseema, McGrath, Sara, Walkowicz, Mitchell J, Sharp, Fiona, Conlon, Joseph E, Fukase, Koichi, Kusumoto, Shoichi, Sweet, Charles, Miyake, Kensuke, Akira, Shizuo, Cotter, Robert J, Goguen, Jon D

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Genome-wide mutant fitness profiling identifies nutritional requirements for optimal growth of Yersinia pestis in deep tissue von Palace, Samantha G, Proulx, Megan K, Lu, Shan, Baker, Richard E, Goguen, Jon D

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Targeting Type III Secretion in Yersinia pestis von PAN, Ning J, BRADY, Michael J, LEONG, John M, GOGUEN, Jon D

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Yersinia pestis escapes entrapment in thrombi by targeting platelet function von Palace, Samantha G., Vitseva, Olga, Proulx, Megan K., Freedman, Jane E., Goguen, Jon D., Koupenova, Milka

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The NLRP12 Inflammasome Recognizes Yersinia pestis von Vladimer, Gregory I., Weng, Dan, Paquette, Sara W. Montminy, Vanaja, Sivapriya Kailasan, Rathinam, Vijay A.K., Aune, Marie Hjelmseth, Conlon, Joseph E., Burbage, Joseph J., Proulx, Megan K., Liu, Qin, Reed, George, Mecsas, Joan C., Iwakura, Yoichiro, Bertin, John, Goguen, Jon D., Fitzgerald, Katherine A., Lien, Egil

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Evaluation of the Role of LcrV-Toll-Like Receptor 2-Mediated Immunomodulation in the Virulence of Yersinia pestis von Pouliot, Kimberly, Pan, Ning, Wang, Shixia, Lu, Shan, Lien, Egil, Goguen, Jon D

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Gain-of-Function Analysis Reveals Important Virulence Roles for the Yersinia pestis Type III Secretion System Effectors YopJ, YopT, and YpkA von Palace, Samantha G, Proulx, Megan K, Szabady, Rose L, Goguen, Jon D

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Manipulation of Interleukin-1β and Interleukin-18 Production by Yersinia pestis Effectors YopJ and YopM and Redundant Impact on Virulence von Ratner, Dmitry, Orning, M. Pontus A., Starheim, Kristian K., Marty-Roix, Robyn, Proulx, Megan K., Goguen, Jon D., Lien, Egil

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Reversion From Methicillin Susceptibility to Methicillin Resistance in Staphylococcus aureus During Treatment of Bacteremia von Proulx, Megan K., Palace, Samantha G., Gandra, Sumanth, Torres, Brenda, Weir, Susan, Stiles, Tracy, Ellison, Richard T., Goguen, Jon D.

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Reply to Gelfand and Cleveland von Proulx, Megan K., Ellison, Richard T., Goguen, Jon D.

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Manipulation of interleukin-1β and interleukin-18 production by Yersinia pestis effectors YopJ and YopM and redundant impact on virulence von Ratner, Dmitry, Orning, M. Pontus A., Starheim, Kristian K., Marty-Roix, Robyn, Proulx, Megan K., Goguen, Jon D., Lien, Egil

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Involvement of CD8+ T cell-mediated immune responses in LcrV DNA vaccine induced protection against lethal Yersinia pestis challenge von Wang, Shixia, Goguen, Jon D, Li, Fusheng, Lu, Shan

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Antigen engineering can play a critical role in the protective immunity elicited by Yersinia pestis DNA vaccines von Wang, Shixia, Mboudjeka, Innocent, Goguen, Jon D, Lu, Shan

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Relative immunogenicity and protection potential of candidate Yersinia Pestis antigens against lethal mucosal plague challenge in Balb/C mice von Wang, Shixia, Joshi, Swati, Mboudjeka, Innocent, Liu, Fangjun, Ling, Tzufan, Goguen, Jon D, Lu, Shan

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RNA expression patterns change dramatically in human neutrophils exposed to bacteria von Subrahmanyam, Yerramilli V. B.K., Yamaga, Shigeru, Prashar, Yatindra, Lee, Helen H., Hoe, Nancy P., Kluger, Yuval, Gerstein, Mark, Goguen, Jon D., Newburger, Peter E., Weissman, Sherman M.

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