Somatic Mutations of the Immunoglobulin Framework Are Generally Required for Broad and Potent HIV-1 Neutralization von Klein, Florian, Diskin, Ron, Scheid, Johannes F., Gaebler, Christian, Mouquet, Hugo, Georgiev, Ivelin S., Pancera, Marie, Zhou, Tongqing, Incesu, Reha-Baris, Fu, Brooks Zhongzheng, Gnanapragasam, Priyanthi N.P., Oliveira, Thiago Y., Seaman, Michael S., Kwong, Peter D., Bjorkman, Pamela J., Nussenzweig, Michel C.

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Antibody 8ANC195 Reveals a Site of Broad Vulnerability on the HIV-1 Envelope Spike von Scharf, Louise, Scheid, Johannes F., Lee, Jeong Hyun, West, Anthony P., Chen, Courtney, Gao, Han, Gnanapragasam, Priyanthi N.P., Mares, René, Seaman, Michael S., Ward, Andrew B., Nussenzweig, Michel C., Bjorkman, Pamela J.

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Broad cross-reactivity across sarbecoviruses exhibited by a subset of COVID-19 donor-derived neutralizing antibodies von Jette, Claudia A., Cohen, Alexander A., Gnanapragasam, Priyanthi N.P., Muecksch, Frauke, Lee, Yu E., Huey-Tubman, Kathryn E., Schmidt, Fabian, Hatziioannou, Theodora, Bieniasz, Paul D., Nussenzweig, Michel C., West, Anthony P., Keeffe, Jennifer R., Bjorkman, Pamela J., Barnes, Christopher O.

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Examination of the contributions of size and avidity to the neutralization mechanisms of the anti-HIV antibodies b12 and 4E10 von Klein, Joshua S, Gnanapragasam, Priyanthi N.P, Galimidi, Rachel P, Foglesong, Christopher P, West, Anthony P. Jr, Bjorkman, Pamela J

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Rapid identification of neutralizing antibodies against SARS-CoV-2 variants by mRNA display von Tanaka, Shiho, Olson, C. Anders, Barnes, Christopher O., Higashide, Wendy, Gonzalez, Marcos, Taft, Justin, Richardson, Ashley, Martin-Fernandez, Marta, Bogunovic, Dusan, Gnanapragasam, Priyanthi N.P., Bjorkman, Pamela J., Spilman, Patricia, Niazi, Kayvan, Rabizadeh, Shahrooz, Soon-Shiong, Patrick

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Broad cross-reactivity across sarbecoviruses exhibited by a subset of COVID-19 donor-derived neutralizing antibodies von Jette, Claudia A., Cohen, Alexander A., Gnanapragasam, Priyanthi N.P., Muecksch, Frauke, Lee, Yu E., Huey-Tubman, Kathryn E., Schmidt, Fabian, Hatziioannou, Theodora, Bieniasz, Paul D., Nussenzweig, Michel C., West, Anthony P., Keeffe, Jennifer R., Bjorkman, Pamela J., Barnes, Christopher O.

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Mosaic nanoparticles elicit cross-reactive immune responses to zoonotic coronaviruses in mice von Cohen, Alexander A, Gnanapragasam, Priyanthi N P, Lee, Yu E, Hoffman, Pauline R, Ou, Susan, Kakutani, Leesa M, Keeffe, Jennifer R, Wu, Hung-Jen, Howarth, Mark, West, Anthony P, Barnes, Christopher O, Nussenzweig, Michel C, Bjorkman, Pamela J

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Mosaic RBD nanoparticles protect against challenge by diverse sarbecoviruses in animal models von Cohen, Alexander A, van Doremalen, Neeltje, Greaney, Allison J, Andersen, Hanne, Sharma, Ankur, Starr, Tyler N, Keeffe, Jennifer R, Fan, Chengcheng, Schulz, Jonathan E, Gnanapragasam, Priyanthi N P, Kakutani, Leesa M, West, Jr, Anthony P, Saturday, Greg, Lee, Yu E, Gao, Han, Jette, Claudia A, Lewis, Mark G, Tan, Tiong K, Townsend, Alain R, Bloom, Jesse D, Munster, Vincent J, Bjorkman, Pamela J

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Construction, characterization, and immunization of nanoparticles that display a diverse array of influenza HA trimers von Cohen, Alexander A, Yang, Zhi, Gnanapragasam, Priyanthi N P, Ou, Susan, Dam, Kim-Marie A, Wang, Haoqing, Bjorkman, Pamela J

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Complex-type N-glycan recognition by potent broadly neutralizing HIV antibodies von Mouquet, Hugo, Scharf, Louise, Euler, Zelda, Liu, Yan, Eden, Caroline, Scheid, Johannes F., Halper-Stromberg, Ariel, Gnanapragasam, Priyanthi N. P., Spencer, Daniel I. R., Seaman, Michael S., Schuitemaker, Hanneke, Feizi, Ten, Nussenzweig, Michel C., Bjorkman, Pamela J.

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Increasing the Potency and Breadth of an HIV Antibody by Using Structure-Based Rational Design von Diskin, Ron, Scheid, Johannes F., Marcovecchio, Paola M., West, Anthony P., Klein, Florian, Gao, Han, Gnanapragasam, Priyanthi N. P., Abadir, Alexander, Seaman, Michael S., Nussenzweig, Michel C., Bjorkman, Pamela J.

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Detection and characterization of the SARS-CoV-2 lineage B.1.526 in New York von West, Anthony P., Wertheim, Joel O., Wang, Jade C., Vasylyeva, Tetyana I., Havens, Jennifer L., Chowdhury, Moinuddin A., Gonzalez, Edimarlyn, Fang, Courtney E., Di Lonardo, Steve S., Hughes, Scott, Rakeman, Jennifer L., Lee, Henry H., Barnes, Christopher O., Gnanapragasam, Priyanthi N. P., Yang, Zhi, Gaebler, Christian, Caskey, Marina, Nussenzweig, Michel C., Keeffe, Jennifer R., Bjorkman, Pamela J.

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B cell genomics behind cross-neutralization of SARS-CoV-2 variants and SARS-CoV von Scheid, Johannes F., Barnes, Christopher O., Eraslan, Basak, Hudak, Andrew, Keeffe, Jennifer R., Cosimi, Lisa A., Brown, Eric M., Muecksch, Frauke, Weisblum, Yiska, Zhang, Shuting, Delorey, Toni, Woolley, Ann E., Ghantous, Fadi, Park, Sung-Moo, Phillips, Devan, Tusi, Betsabeh, Huey-Tubman, Kathryn E., Cohen, Alexander A., Gnanapragasam, Priyanthi N.P., Rzasa, Kara, Hatziioanno, Theodora, Durney, Michael A., Gu, Xiebin, Tada, Takuya, Landau, Nathaniel R., West, Anthony P., Rozenblatt-Rosen, Orit, Seaman, Michael S., Baden, Lindsey R., Graham, Daniel B., Deguine, Jacques, Bieniasz, Paul D., Regev, Aviv, Hung, Deborah, Bjorkman, Pamela J., Xavier, Ramnik J.

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Electron tomography visualization of HIV-1 fusion with target cells using fusion inhibitors to trap the pre-hairpin intermediate von Ladinsky, Mark S, Gnanapragasam, Priyanthi Np, Yang, Zhi, West, Anthony P, Kay, Michael S, Bjorkman, Pamela J

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Neutralizing monoclonal antibodies elicited by mosaic RBD nanoparticles bind conserved sarbecovirus epitopes von Fan, Chengcheng, Cohen, Alexander A., Park, Miso, Hung, Alfur Fu-Hsin, Keeffe, Jennifer R., Gnanapragasam, Priyanthi N.P., Lee, Yu E., Gao, Han, Kakutani, Leesa M., Wu, Ziyan, Kleanthous, Harry, Malecek, Kathryn E., Williams, John C., Bjorkman, Pamela J.

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HIV-1 CD4-binding site germline antibody–Env structures inform vaccine design von Dam, Kim-Marie A., Barnes, Christopher O., Gristick, Harry B., Schoofs, Till, Gnanapragasam, Priyanthi N. P., Nussenzweig, Michel C., Bjorkman, Pamela J.

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ESCRT recruitment to SARS-CoV-2 spike induces virus-like particles that improve mRNA vaccines von Hoffmann, Magnus A.G., Yang, Zhi, Huey-Tubman, Kathryn E., Cohen, Alexander A., Gnanapragasam, Priyanthi N.P., Nakatomi, Leesa M., Storm, Kaya N., Moon, Woohyun J., Lin, Paulo J.C., West, Anthony P., Bjorkman, Pamela J.

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Proactive vaccination using multiviral Quartet Nanocages to elicit broad anti-coronavirus responses von Hills, Rory A., Tan, Tiong Kit, Cohen, Alexander A., Keeffe, Jennifer R., Keeble, Anthony H., Gnanapragasam, Priyanthi N. P., Storm, Kaya N., Rorick, Annie V., West, Anthony P., Hill, Michelle L., Liu, Sai, Gilbert-Jaramillo, Javier, Afzal, Madeeha, Napier, Amy, Admans, Gabrielle, James, William S., Bjorkman, Pamela J., Townsend, Alain R., Howarth, Mark R.

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Nanoparticles presenting clusters of CD4 expose a universal vulnerability of HIV-1 by mimicking target cells von Hoffmann, Magnus A. G., Bar-On, Yotam, Yang, Zhi, Gristick, Harry B., Gnanapragasam, Priyanthi N. P., Vielmetter, Jost, Nussenzweig, Michel C., Bjorkman, Pamela J.

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Inhibitory effect of HIV-specific neutralizing IgA on mucosal transmission of HIV in humanized mice von Hur, Eun Mi, Patel, Sonal N., Shimizu, Saki, Rao, Dinesh S., Gnanapragasam, Priyanthi N.P., An, Dong Sung, Yang, Lili, Baltimore, David

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