Predictive Genomic Biomarkers of Hormonal Therapy Versus Chemotherapy Benefit in Metastatic Castration-resistant Prostate Cancer von Graf, Ryon P., Fisher, Virginia, Mateo, Joaquin, Gjoerup, Ole V., Madison, Russell W., Raskina, Kira, Tukachinsky, Hanna, Creeden, James, Cunningham, Rachel, Huang, Richard S.P., Mata, Douglas A., Ross, Jeffrey S., Oxnard, Geoffrey R., Venstrom, Jeffrey M., Zurita, Amado J.

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Genomic Analysis of Circulating Tumor DNA in 3,334 Patients with Advanced Prostate Cancer Identifies Targetable BRCA Alterations and AR Resistance Mechanisms von Tukachinsky, Hanna, Madison, Russell W., Chung, Jon H., Gjoerup, Ole V., Severson, Eric A., Dennis, Lucas, Fendler, Bernard J., Morley, Samantha, Zhong, Lei, Graf, Ryon P., Ross, Jeffrey S., Alexander, Brian M., Abida, Wassim, Chowdhury, Simon, Ryan, Charles J., Fizazi, Karim, Golsorkhi, Tony, Watkins, Simon P., Simmons, Andrew, Loehr, Andrea, Venstrom, Jeffrey M., Oxnard, Geoffrey R.

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Clinical and analytical validation of FoundationOne®CDx, a comprehensive genomic profiling assay for solid tumors von Milbury, Coren A, Creeden, James, Yip, Wai-Ki, Smith, David L, Pattani, Varun, Maxwell, Kristi, Sawchyn, Bethany, Gjoerup, Ole, Meng, Wei, Skoletsky, Joel, Concepcion, Alvin D, Tang, Yanhua, Bai, Xiaobo, Dewal, Ninad, Ma, Pei, Bailey, Shannon T, Thornton, James, Pavlick, Dean C, Frampton, Garrett M, Lieber, Daniel, White, Jared, Burns, Christine, Vietz, Christine

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Functional connection between Rad51 and PML in homology-directed repair von Boichuk, Sergei, Hu, Liang, Makielski, Kathleen, Pandolfi, Pier Paolo, Gjoerup, Ole V

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STRIPAK directs PP2A activity toward MAP4K4 to promote oncogenic transformation of human cells von Kim, Jong Wook, Berrios, Christian, Kim, Miju, Schade, Amy E., Adelmant, Guillaume, Yeerna, Huwate, Damato, Emily, Iniguez, Amanda Balboni, Florens, Laurence, Washburn, Michael P., Stegmaier, Kim, Gray, Nathanael S., Tamayo, Pablo, Gjoerup, Ole, Marto, Jarrod A., DeCaprio, James, Hahn, William C.

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T antigen mutations are a human tumor-specific signature for Merkel cell polyomavirus von Shuda, Masahiro, Feng, Huichen, Kwun, Hyun Jin, Rosen, Steven T, Gjoerup, Ole, Moore, Patrick S, Chang, Yuan

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Multiple DNA Damage Signaling and Repair Pathways Deregulated by Simian Virus 40 Large T Antigen von Boichuk, Sergei, Hu, Liang, Hein, Jennifer, Gjoerup, Ole V

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The Pan-Tumor Landscape of Targetable Kinase Fusions in Circulating Tumor DNA von Lee, Jessica K, Hazar-Rethinam, Mehlika, Decker, Brennan, Gjoerup, Ole, Madison, Russell W, Lieber, Daniel S, Chung, Jon H, Schrock, Alexa B, Creeden, James, Venstrom, Jeffrey, Alexander, Brian, Oxnard, Geoffrey R

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Tissue and liquid biopsy profiling reveal convergent tumor evolution and therapy evasion in breast cancer von Sivakumar, Smruthy, Jin, Dexter X., Tukachinsky, Hanna, Murugesan, Karthikeyan, McGregor, Kimberly, Danziger, Natalie, Pavlick, Dean, Gjoerup, Ole, Ross, Jeffrey S., Harmon, Robert, Chung, Jon, Decker, Brennan, Dennis, Lucas, Frampton, Garrett M., Molinero, Luciana, Oesterreich, Steffi, Venstrom, Jeffrey M., Oxnard, Geoffrey R., Hegde, Priti S., Sokol, Ethan S.

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Comparative Genomic Analysis of Intrahepatic Cholangiocarcinoma: Biopsy Type, Ancestry, and Testing Patterns von Israel, Mason A., Danziger, Natalie, McGregor, Kimberly A., Murugesan, Karthikeyan, Gjoerup, Ole, Sokol, Ethan S., Tukachinsky, Hanna, Kurzrock, Razelle, Kato, Shumei, Sicklick, Jason K., Nimeiri, Halla S., Oxnard, Geoffrey R., Ross, Jeffrey S.

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An alternative splicing switch in FLNB promotes the mesenchymal cell state in human breast cancer von Li, Ji, Choi, Peter S, Chaffer, Christine L, Labella, Katherine, Hwang, Justin H, Giacomelli, Andrew O, Kim, Jong Wook, Ilic, Nina, Doench, John G, Ly, Seav Huong, Dai, Chao, Hagel, Kimberly, Hong, Andrew L, Gjoerup, Ole, Goel, Shom, Ge, Jennifer Y, Root, David E, Zhao, Jean J, Brooks, Angela N, Weinberg, Robert A, Hahn, William C

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SIK1 couples LKB1 to p53-dependent anoikis and suppresses metastasis von Cheng, Hailing, Liu, Pixu, Wang, Zhigang C, Zou, Lihua, Santiago, Stephanie, Garbitt, Victoria, Gjoerup, Ole V, Iglehart, J Dirk, Miron, Alexander, Richardson, Andrea L, Hahn, William C, Zhao, Jean J

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Renal medullary carcinomas depend upon SMARCB1 loss and are sensitive to proteasome inhibition von Hong, Andrew L, Tseng, Yuen-Yi, Wala, Jeremiah A, Kim, Won-Jun, Kynnap, Bryan D, Doshi, Mihir B, Kugener, Guillaume, Sandoval, Gabriel J, Howard, Thomas P, Li, Ji, Yang, Xiaoping, Tillgren, Michelle, Ghandi, Mahmhoud, Sayeed, Abeer, Deasy, Rebecca, Ward, Abigail, McSteen, Brian, Labella, Katherine M, Keskula, Paula, Tracy, Adam, Connor, Cora, Clinton, Catherine M, Church, Alanna J, Crompton, Brian D, Janeway, Katherine A, Van Hare, Barbara, Sandak, David, Gjoerup, Ole, Bandopadhayay, Pratiti, Clemons, Paul A, Schreiber, Stuart L, Root, David E, Gokhale, Prafulla C, Chi, Susan N, Mullen, Elizabeth A, Roberts, Charles Wm, Kadoch, Cigall, Beroukhim, Rameen, Ligon, Keith L, Boehm, Jesse S, Hahn, William C

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Simian Virus 40 Large T Antigen Disrupts Genome Integrity and Activates a DNA Damage Response via Bub1 Binding von Hein, Jennifer, Boichuk, Sergei, Wu, Jiaping, Cheng, Yuan, Freire, Raimundo, Jat, Parmjit S, Roberts, Thomas M, Gjoerup, Ole V

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Molecular residual disease detection in resected, muscle-invasive urothelial cancer with a tissue-based comprehensive genomic profiling–informed personalized monitoring assay von Powles, Thomas, Young, Amanda, Nimeiri, Halla, Madison, Russell W., Fine, Alexander, Zollinger, Daniel R., Huang, Yanmei, Xu, Chang, Gjoerup, Ole V., Aushev, Vasily N., Wu, Hsin-Ta, Aleshin, Alexey, Carter, Corey, Davarpanah, Nicole, Degaonkar, Viraj, Gupta, Pratyush, Mariathasan, Sanjeev, Schleifman, Erica, Assaf, Zoe June, Oxnard, Geoffrey, Hegde, Priti S.

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Protein phosphatase 2A regulates life and death decisions via Akt in a context-dependent manner von Andrabi, Shaida, Gjoerup, Ole V, Kean, Jennifer A, Roberts, Thomas M, Schaffhausen, Brian

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Comprehensive Genomic Profiling (CGP)-Informed Personalized Molecular Residual Disease (MRD) Detection: An Exploratory Analysis from the PREDATOR Study of Metastatic Colorectal Can... von Lonardi, Sara, Nimeiri, Halla, Xu, Chang, Zollinger, Daniel R, Madison, Russell W, Fine, Alexander D, Gjoerup, Ole, Rasola, Cosimo, Angerilli, Valentina, Sharma, Shruti, Wu, Hsin-Ta, Palsuledesai, Charuta C, Malhotra, Meenakshi, Aleshin, Alexey, Loupakis, Fotios, Renkonen, Elise, Hegde, Priti, Fassan, Matteo

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Prevalence of inferred clonal hematopoiesis (CH) detected on comprehensive genomic profiling (CGP) of solid tumor tissue or circulating tumor DNA (ctDNA) von Antonarakis, Emmanuel S., Kuang, Zheng, Tukachinsky, Hanna, Parachoniak, Christine, Kelly, Andrew David, Gjoerup, Ole, Aiyer, Aparna, Severson, Eric Allan, Pavlick, Dean C., Frampton, Garrett M., Venstrom, Jeffrey Michael, Oxnard, Geoffrey R.

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Cellular and viral factors regulating Merkel cell polyomavirus replication von Feng, Huichen, Kwun, Hyun Jin, Liu, Xi, Gjoerup, Ole, Stolz, Donna B, Chang, Yuan, Moore, Patrick S

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SMAD4 represses FOSL1 expression and pancreatic cancer metastatic colonization von Dai, Chao, Rennhack, Jonathan P., Arnoff, Taylor E., Thaker, Maneesha, Younger, Scott T., Doench, John G., Huang, August Yue, Yang, Annan, Aguirre, Andrew J., Wang, Belinda, Mun, Evan, O’Connell, Joyce T., Huang, Ying, Labella, Katherine, Talamas, Jessica A., Li, Ji, Ilic, Nina, Hwang, Justin, Hong, Andrew L., Giacomelli, Andrew O., Gjoerup, Ole, Root, David E., Hahn, William C.

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