Pathobiology of Candida auris infection analyzed by multiplexed imaging and single cell analysis von Chadwick, Chrystal, De Jesus, Magdia, Ginty, Fiona, Martinez, Jessica S

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Highly multiplexed single-cell analysis of formalin-fixed, paraffin-embedded cancer tissue von Gerdes, Michael J., Sevinsky, Christopher J., Sood, Anup, Adak, Sudeshna, Bello, Musodiq O., Bordwell, Alexander, Can, Ali, Corwin, Alex, Dinn, Sean, Filkins, Robert J., Hollman, Denise, Kamath, Vidya, Kaanumalle, Sireesha, Kenny, Kevin, Larsen, Melinda, Lazare, Michael, Li, Qing, Lowes, Christina, McCulloch, Colin C., McDonough, Elizabeth, Montalto, Michael C., Pang, Zhengyu, Rittscher, Jens, Santamaria-Pang, Alberto, Sarachan, Brion D., Seel, Maximilian L., Seppo, Antti, Shaikh, Kashan, Sui, Yunxia, Zhang, Jingyu, Ginty, Fiona

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Accelerating cutaneous healing in a rodent model of type II diabetes utilizing non-invasive focused ultrasound targeted at the spleen von Morton, Christine, Cotero, Victoria, Ashe, Jeffrey, Ginty, Fiona, Puleo, Christopher

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Understanding heterogeneous tumor microenvironment in metastatic melanoma von Yan, Yiyi, Leontovich, Alexey A, Gerdes, Michael J, Desai, Keyur, Dong, Jinhong, Sood, Anup, Santamaria-Pang, Alberto, Mansfield, Aaron S, Chadwick, Chrystal, Zhang, Rong, Nevala, Wendy K, Flotte, Thomas J, Ginty, Fiona, Markovic, Svetomir N

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Spatial domain analysis predicts risk of colorectal cancer recurrence and infers associated tumor microenvironment networks von Uttam, Shikhar, Stern, Andrew M., Sevinsky, Christopher J., Furman, Samantha, Pullara, Filippo, Spagnolo, Daniel, Nguyen, Luong, Gough, Albert, Ginty, Fiona, Lansing Taylor, D., Chakra Chennubhotla, S.

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Efficacy and tolerability of anti-programmed death-ligand 1 (PD-L1) antibody (Avelumab) treatment in advanced thymoma von Rajan, Arun, Heery, Christopher R., Thomas, Anish, Mammen, Andrew L., Perry, Susan, O’Sullivan Coyne, Geraldine, Guha, Udayan, Berman, Arlene, Szabo, Eva, Madan, Ravi A., Ballester, Leomar Y., Pittaluga, Stefania, Donahue, Renee N., Tsai, Yo-Ting, Lepone, Lauren M., Chin, Kevin, Ginty, Fiona, Sood, Anup, Hewitt, Stephen M., Schlom, Jeffrey, Hassan, Raffit, Gulley, James L.

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AZGP1 deficiency promotes angiogenesis in prostate cancer von Wen, Ru M, Qiu, Zhengyuan, Marti, G Edward W, Peterson, Eric E, Marques, Fernando Jose Garcia, Bermudez, Abel, Wei, Yi, Nolley, Rosalie, Lam, Nathan, Polasko, Alex LaPat, Chiu, Chun-Lung, Zhang, Dalin, Cho, Sanghee, Karageorgos, Grigorios Marios, McDonough, Elizabeth, Chadwick, Chrystal, Ginty, Fiona, Jung, Kyeong Joo, Machiraju, Raghu, Mallick, Parag, Crowley, Laura, Pollack, Jonathan R, Zhao, Hongjuan, Pitteri, Sharon J, Brooks, James D

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Epithelial TGFβ engages growth-factor signalling to circumvent apoptosis and drive intestinal tumourigenesis with aggressive features von Flanagan, Dustin J., Amirkhah, Raheleh, Vincent, David F., Gunduz, Nuray, Gentaz, Pauline, Cammareri, Patrizia, McCooey, Aoife J., McCorry, Amy M. B., Fisher, Natalie C., Davis, Hayley L., Ridgway, Rachel A., Lohuis, Jeroen, Leach, Joshua D. G., Jackstadt, Rene, Gilroy, Kathryn, Mariella, Elisa, Nixon, Colin, Clark, William, Hedley, Ann, Markert, Elke K., Strathdee, Douglas, Bartholin, Laurent, Redmond, Keara L., Kerr, Emma M., Longley, Daniel B., Ginty, Fiona, Cho, Sanghee, Coleman, Helen G., Loughrey, Maurice B., Bardelli, Alberto, Maughan, Timothy S., Campbell, Andrew D., Lawler, Mark, Leedham, Simon J., Barry, Simon T., Inman, Gareth J., van Rheenen, Jacco, Dunne, Philip D., Sansom, Owen J.

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Precision of GE Lunar iDXA for the Measurement of Total and Regional Body Composition in Nonobese Adults von Rothney, Megan P, Martin, Francois-Pierre, Xia, Yi, Beaumont, Maurice, Davis, Cynthia, Ergun, David, Fay, Laurent, Ginty, Fiona, Kochhar, Sunil, Wacker, Wynn, Rezzi, Serge

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Deep learning-based automated pipeline for blood vessel detection and distribution analysis in multiplexed prostate cancer images von Karageorgos, Grigorios M, Cho, Sanghee, McDonough, Elizabeth, Chadwick, Chrystal, Ghose, Soumya, Owens, Jonathan, Jung, Kyeong Joo, Machiraju, Raghu, West, Robert, Brooks, James D, Mallick, Parag, Ginty, Fiona

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Integrated multiplex analysis of cell death regulators in stage II colorectal cancer suggests patients with ‘persister’ cell profiles fail to benefit from adjuvant chemotherapy von Cho, Sanghee, McDonough, Elizabeth, Graf, John, Shia, Jinru, Firat, Canan, Urganci, Nil, Surrette, Christine, Lindner, Andreas, Salvucci, Manuela, Matveeva, Anna, Kisakol, Batuhan, O’Grady, Anthony, Azimi, Mohammadreza, Burke, John P, McNamara, Deborah A, McDade, Simon, Longley, Daniel B, Prehn, Jochen HM, Ginty, Fiona

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3D reconstruction of skin and spatial mapping of immune cell density, vascular distance and effects of sun exposure and aging von Ghose, Soumya, Ju, Yingnan, McDonough, Elizabeth, Ho, Jonhan, Karunamurthy, Arivarasan, Chadwick, Chrystal, Cho, Sanghee, Rose, Rachel, Corwin, Alex, Surrette, Christine, Martinez, Jessica, Williams, Eric, Sood, Anup, Al-Kofahi, Yousef, Falo, Louis D., Börner, Katy, Ginty, Fiona

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Abstract LB-088: Exploratory multiplex tissue image analysis of the impact of heterogeneity in the microenvironment of primary colorectal cancer on apoptosis markers in patients von Lindner, Andreas Urlich, Salvucci, Manuela, Stachtea, Xanthi, Carberry, Steven, Dunne, Philip D., Sood, Anup, McDonough, Elizabeth, Cho, Sanghee, Laurent-Puig, Pierre, Schaeybroeck, Sandra Van, Salto-Tellez, Manuel, Graf, John F., Rehm, Markus, Lawler, Mark, Longley, Daniel B., Fiona, Fiona Ginty, Prehn, Jochen H.

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The Relative Distribution of Membranous and Cytoplasmic Met Is a Prognostic Indicator in Stage I and II Colon Cancer von GINTY, Fiona, ADAK, Sudeshna, CAN, Ali, GERDES, Michael, LARSEN, Melinda, CLINE, Harvey, FILKINS, Robert, ZHENGYU PANG, QING LI, MONTALTO, Michael C

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Prolyl 4-hydroxylase alpha 1 protein expression risk-stratifies early stage colorectal cancer von Tanaka, Atsushi, Zhou, Yihua, Shia, Jinru, Ginty, Fiona, Ogawa, Makiko, Klimstra, David S., Hendrickson, Ronald C., Wang, Julia Y., Roehrl, Michael H.

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Pointwise mutual information quantifies intratumor heterogeneity in tissue sections labeled with multiple fluorescent biomarkers von Spagnolo, Daniel M., Gyanchandani, Rekha, Al-Kofahi, Yousef, Stern, Andrew M., Lezon, Timothy R., Gough, Albert, Meyer, Dan E., Ginty, Fiona, Sarachan, Brion, Fine, Jeffrey, Lee, Adrian V., Taylor, D. Lansing, Chennubhotla, S. Chakra

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FLINO: a new method for immunofluorescence bioimage normalization von Graf, John, Cho, Sanghee, McDonough, Elizabeth, Corwin, Alex, Sood, Anup, Lindner, Andreas, Salvucci, Manuela, Stachtea, Xanthi, Van Schaeybroeck, Sandra, Dunne, Philip D, Laurent-Puig, Pierre, Longley, Daniel, Prehn, Jochen H M, Ginty, Fiona

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Abstract PO-084: Protein marker heterogeneity in breast cancer subtypes measured using immunofluorescence protein multiplexing and quantitative, single cell image analysis von Cheung, Alison M., Wang, Dan, Liu, Kela, Ginty, Fiona, Nofech-Mozes, Sharon, Bayani, Jane, Bartlett, John M.S., Martel, Anne, Yaffe, Martin J.

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An atlas of inter- and intra-tumor heterogeneity of apoptosis competency in colorectal cancer tissue at single-cell resolution von Lindner, Andreas Ulrich, Salvucci, Manuela, McDonough, Elizabeth, Cho, Sanghee, Stachtea, Xanthi, O’Connell, Emer P., Corwin, Alex D., Santamaria-Pang, Alberto, Carberry, Steven, Fichtner, Michael, Van Schaeybroeck, Sandra, Laurent-Puig, Pierre, Burke, John P., McNamara, Deborah A., Lawler, Mark, Sood, Anup, Graf, John F., Rehm, Markus, Dunne, Philip D., Longley, Daniel B., Ginty, Fiona, Prehn, Jochen H. M.

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Advances and Perspectives for the Human BioMolecular Atlas Program (HuBMAP) von Jain, Sanjay, Pei, Liming, Spraggins, Jeffrey M., Angelo, Michael, Carson, James P., Gehlenborg, Nils, Ginty, Fiona, Gonçalves, Joana P., Hagood, James S., Hickey, John W., Kelleher, Neil L., Laurent, Louise C., Lin, Shin, Lin, Yiing, Liu, Huiping, Naba, Alexandra, Nakayasu, Ernesto S., Qian, Wei-Jun, Radtke, Andrea, Robson, Paul, Stockwell, Brent R., Van de Plas, Raf, Vlachos, Ioannis S., Zhou, Mowei, Börner, Katy, Snyder, Michael P.

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