Nectin-4: a new prognostic biomarker for efficient therapeutic targeting of primary and metastatic triple-negative breast cancer von M-Rabet, M., Cabaud, O., Josselin, E., Finetti, P., Castellano, R., Farina, A., Agavnian-Couquiaud, E., Saviane, G., Collette, Y., Viens, P., Gonçalves, A., Ginestier, C., Charafe-Jauffret, E., Birnbaum, D., Olive, D., Bertucci, F., Lopez, M.

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Gene expression profiling of breast cell lines identifies potential new basal markers von CHARAFE-JAUFFRET, E, GINESTIER, C, BERTUCCI, F, MONVILLE, F, FINETTI, P, ADELAÏDE, J, CERVERA, N, FEKAIRI, S, XERRI, L, JACQUEMIER, J, BIRNBAUM, D

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Junctional recruitment of mammalian Scribble relies on E-cadherin engagement von NAVARRO, Christel, NOLA, Sebastien, BIRNBAUM, Daniel, BORG, Jean-Paul, AUDEBERT, Stéphane, SANTONI, Marie-Josée, ARSANTO, Jean-Pierre, GINESTIER, Christophe, MARCHETTO, Sylvie, JACQUEMIER, Jocelyne, ISNARDON, Daniel, LE BIVIC, André

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ERBB2 phosphorylation and trastuzumab sensitivity of breast cancer cell lines von GINESTIER, C, ADELAÏDE, J, JACQUEMIER, J, VIENS, P, BIRNBAUM, D, GONCALVES, A, REPELLINI, L, SIRCOULOMB, F, LETESSIER, A, FINETTI, P, GENEIX, J, CHARAFE -JAUFFRET, E, BERTUCCI, F

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Correlated break at PARK2/FRA6E and loss of AF-6/Afadin protein expression are associated with poor outcome in breast cancer von LETESSIER, A, GARRIDO-URBANI, S, VIENS, P, CHARAFE -JAUFFRET, E, JACQUEMIER, J, BIRNBAUM, D, LOPEZ, M, CHAFFANET, M, GINESTIER, C, FOURNIER, G, ESTERNI, B, MONVILLE, F, ADELAÏDE, J, GENEIX, J, XERRI, L, DUBREUIL, P

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CXCR1 blockade selectively targets human breast cancer stem cells in vitro and in xenografts von Ginestier, Christophe, Liu, Suling, Diebel, Mark E, Korkaya, Hasan, Luo, Ming, Brown, Marty, Wicinski, Julien, Cabaud, Olivier, Charafe-Jauffret, Emmanuelle, Birnbaum, Daniel, Guan, Jun-Lin, Dontu, Gabriela, Wicha, Max S

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Gene expression profiling of colon cancer by DNA microarrays and correlation with histoclinical parameters von BERTUCCI, Francois, SALAS, Sébastien, VICTORERO, Geneviève, VIRET, Frédéric, OLLENDORFF, Vincent, FERT, Vincent, GIOVANINNI, Marc, DELPERO, Jean-Robert, NGUYEN, Catherine, VIENS, Patrice, MONGES, Geneviève, BIRNBAUM, Daniel, EYSTERIES, Séverine, HOULGATTE, Rémi, NASSER, Valéry, FINETTI, Pascal, GINESTIER, Christophe, CHARAFE-JAUFFRET, Emmanuelle, LORIOD, Béatrice, BACHELART, Loic, MONTFORT, Jérome

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Abstract P2-10-02: AVASTEM – Stem cells inhibition by bevacizumab in combination with neoadjuvant chemotherapy for locally advanced breast cancers: A prospective proof of concept r... von Sabatier, R, Charafe-Jauffret, E, Pierga, J-Y, Curé, H, Lambaudie, E, Houvenaeghel, G, Ginestier, C, Sfumato, P, Extra, J-M, Gonçalves, A

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S17 Breast cancer stem cells: Getting to treat the core von Wicha, M.S, Ginestier, C, Dontu, G, Liu, S, Clouthier, S, Charaafe-Jauffret, E

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Protein expression profiling identifies subclasses of breast cancer and predicts prognosis von JACQUEMIER, Jocelyne, GINESTIER, Christophe, MARANINCHI, Dominique, VIENS, Patrice, BIRNBAUM, Daniel, BERTUCCI, Francois, ROUGEMONT, Jacques, BARDOU, Valérie-Jeanne, CHARAFE-JAUFFRET, Emmanuelle, GENEIX, Jeannine, ADELAÏDE, José, KOKI, Alane, HOUVENAEGHEL, Gilles, HASSOUN, Jacques

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Comprehensive Profiling of 8p11-12 Amplification in Breast Cancer von Gelsi-Boyer, Véronique, Orsetti, Béatrice, Cervera, Nathalie, Finetti, Pascal, Sircoulomb, Fabrice, Rougé, Carole, Lasorsa, Laurence, Letessier, Anne, Ginestier, Christophe, Monville, Florence, Esteyriès, Séverine, Adélaïde, José, Esterni, Benjamin, Henry, Catherine, Ethier, Stephen P, Bibeau, Frédéric, Mozziconacci, Marie-Joëlle, Charafe-Jauffret, Emmanuelle, Jacquemier, Jocelyne, Bertucci, François, Birnbaum, Daniel, Theillet, Charles, Chaffanet, Max

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Abstract P5-06-02: Ex vivo CSC assays for personalized testing of drug susceptibility in advanced breast cancer von Charafe-Jauffret, E, Wicinski, J, Cabaud, O, Lopez, M, Audebert, S, Adelaide, J, Chaffanet, M, Guille, A, Goncalves, A, Bertucci, F, Birnbaum, D, Ginestier, C

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Immunophenotypic analysis of inflammatory breast cancers: identification of an 'inflammatory signature' von Charafe-Jauffret, Emmanuelle, Tarpin, Carole, Bardou, Valérie-Jeanne, Bertucci, François, Ginestier, Christophe, Braud, Anne-Chantal, Puig, Brigitte, Geneix, Jeannine, Hassoun, Jacques, Birnbaum, Daniel, Jacquemier, Jocelyne, Viens, Patrice

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Reciprocal translocations in breast tumor cell lines: Cloning of a t(3;20) that targets the FHIT gene von Popovici, Cornel, Basset, Céline, Bertucci, François, Orsetti, Béatrice, Adélaide, José, Mozziconacci, Marie-Joëlle, Conte, Nathalie, Murati, Anne, Ginestier, Christophe, Charafe-Jauffret, Emmanuelle, Ethier, Stephen P., Lafage-Pochitaloff, Marina, Theillet, Charles, Birnbaum, Daniel, Chaffanet, Max

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Typical medullary breast carcinomas have a basal/myoepithelial phenotype von Jacquemier, Jocelyne, Padovani, Laetitia, Rabayrol, Laetitia, Lakhani, Sunil R, Penault-Llorca, Frédérique, Denoux, Yves, Fiche, Maryse, Figueiro, Paulo, Maisongrosse, Véronique, Ledoussal, Viviane, Martinez Penuela, Jose, Udvarhely, Nora, El Makdissi, George, Ginestier, Christophe, Geneix, Jeannine, Charafe-Jauffret, Emmanuelle, Xerri, Luc, Eisinger, François, Birnbaum, Daniel, Sobol, Hagay

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Identification and validation of an ERBB2 gene expression signature in breast cancers von BERTUCCI, Francois, BORIE, Nathalie, HERMITTE, Fabienne, HASSOUN, Jacques, DEBONO, Stéphane, VIENS, Patrice, FERT, Vincent, JACQUEMIER, Jocelyne, BIRNBAUM, Daniel, GINESTIER, Christophe, GROULET, Agnès, CHARAFE-JAUFFRET, Emmanuelle, ADELAÏDE, José, GENEIX, Jeannine, BACHELART, Loïc, FINETTI, Pascal, KOKI, Alane

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TACC1-chTOG-Aurora A protein complex in breast cancer von CONTE, Nathalie, DELAVAL, Bénédicte, GINESTIER, Christophe, FERRAND, Alexia, ISNARDON, Daniel, LARROQUE, Christian, PRIGENT, Claude, SERAPHIN, Bertrand, JACQUEMIER, Jocelyne, BIRNBAUM, Daniel

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27 INVITED ALDH1 is a marker of normal and cancer breast stem cells and a predictor of poor clinical outcome von Dontu, G, Ginestier, C, Wicha, M

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Distinct and Complementary Information Provided by Use of Tissue and DNA Microarrays in the Study of Breast Tumor Markers von Ginestier, Christophe, Charafe-Jauffret, Emmanuelle, Bertucci, François, Eisinger, François, Geneix, Jeannine, Bechlian, Didier, Conte, Nathalie, Adélaïde, José, Toiron, Yves, Nguyen, Catherine, Viens, Patrice, Mozziconacci, Marie-Joelle, Houlgatte, Rémi, Birnbaum, Daniel, Jacquemier, Jocelyne

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Abstract P4-13-23: Next-generation sequencing (NGS), array comparative genomic hybridization (aCGH) and patient-derived tumor xenograft (PDX) for precision medicine in advanced bre... von Gonçalves, A, Bertucci, F, Chaffanet, M, Guille, A, Garnier, S, Adelaide, J, Carbuccia, N, Brunelle, S, Piana, G, Cabaud, O, Thomassin-Piana, J, Paciencia-Gros, M, Chereau-Ewald, E, Lambaudie, E, Sabatier, R, Tarpin, C, Provansal, M, Jalaguier-Coudray, A, Extra, J-M, Sarran, A, Pakradouni, J, Viens, P, Lopez, M, Ginestier, C, Charafe-Jauffret, E, Birnbaum, D

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