Glioblastoma stem cells: lessons from the tumor hierarchy in a lethal cancer von Gimple, Ryan C, Bhargava, Shruti, Dixit, Deobrat, Rich, Jeremy N

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RAS: Striking at the Core of the Oncogenic Circuitry von Gimple, Ryan C., Wang, Xiuxing

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Three-dimensional bioprinted glioblastoma microenvironments model cellular dependencies and immune interactions von Tang, Min, Xie, Qi, Gimple, Ryan C., Zhong, Zheng, Tam, Trevor, Tian, Jing, Kidwell, Reilly L., Wu, Qiulian, Prager, Briana C., Qiu, Zhixin, Yu, Aaron, Zhu, Zhe, Mesci, Pinar, Jing, Hui, Schimelman, Jacob, Wang, Pengrui, Lee, Derrick, Lorenzini, Michael H., Dixit, Deobrat, Zhao, Linjie, Bhargava, Shruti, Miller, Tyler E., Wan, Xueyi, Tang, Jing, Sun, Bingjie, Cravatt, Benjamin F., Muotri, Alysson R., Chen, Shaochen, Rich, Jeremy N.

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Brain cancer stem cells: resilience through adaptive plasticity and hierarchical heterogeneity von Gimple, Ryan C., Yang, Kailin, Halbert, Matthew E., Agnihotri, Sameer, Rich, Jeremy N.

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Functional Enhancers Shape Extrachromosomal Oncogene Amplifications von Morton, Andrew R., Dogan-Artun, Nergiz, Faber, Zachary J., MacLeod, Graham, Bartels, Cynthia F., Piazza, Megan S., Allan, Kevin C., Mack, Stephen C., Wang, Xiuxing, Gimple, Ryan C., Wu, Qiulian, Rubin, Brian P., Shetty, Shashirekha, Angers, Stephane, Dirks, Peter B., Sallari, Richard C., Lupien, Mathieu, Rich, Jeremy N., Scacheri, Peter C.

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Epitranscriptomic editing of the RNA N6-methyladenosine modification by dCasRx conjugated methyltransferase and demethylase von Xia, Zhen, Tang, Min, Ma, Jiayan, Zhang, Hongyan, Gimple, Ryan C, Prager, Briana C, Tang, Hongzhen, Sun, Chongran, Liu, Fuyi, Lin, Peng, Mei, Yutang, Du, Ruoxin, Rich, Jeremy N, Xie, Qi

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MYC-Regulated Mevalonate Metabolism Maintains Brain Tumor-Initiating Cells von Wang, Xiuxing, Huang, Zhi, Wu, Qiulian, Prager, Briana C, Mack, Stephen C, Yang, Kailin, Kim, Leo J Y, Gimple, Ryan C, Shi, Yu, Lai, Sisi, Xie, Qi, Miller, Tyler E, Hubert, Christopher G, Song, Anne, Dong, Zhen, Zhou, Wenchao, Fang, Xiaoguang, Zhu, Zhe, Mahadev, Vaidehi, Bao, Shideng, Rich, Jeremy N

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FBXO44 promotes DNA replication-coupled repetitive element silencing in cancer cells von Shen, Jia Z., Qiu, Zhixin, Wu, Qiulian, Finlay, Darren, Garcia, Guillermina, Sun, Dahui, Rantala, Juha, Barshop, William, Hope, Jennifer L., Gimple, Ryan C., Sangfelt, Olle, Bradley, Linda M., Wohlschlegel, James, Rich, Jeremy N., Spruck, Charles

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Targeting Glioblastoma Stem Cells through Disruption of the Circadian Clock von Dong, Zhen, Zhang, Guoxin, Qu, Meng, Gimple, Ryan C, Wu, Qiulian, Qiu, Zhixin, Prager, Briana C, Wang, Xiuxing, Kim, Leo J Y, Morton, Andrew R, Dixit, Deobrat, Zhou, Wenchao, Huang, Haidong, Li, Bin, Zhu, Zhe, Bao, Shideng, Mack, Stephen C, Chavez, Lukas, Kay, Steve A, Rich, Jeremy N

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Adipocytes promote breast tumorigenesis through TAZ-dependent secretion of Resistin von Gao, Yuhao, Chen, Xiaosong, He, Qing, Gimple, Ryan C., Liao, Yajin, Wang, Liang, Wu, Rong, Xie, Qi, Rich, Jeremy N., Shen, Kunwei, Yuan, Zengqiang

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Reciprocal Signaling between Glioblastoma Stem Cells and Differentiated Tumor Cells Promotes Malignant Progression von Wang, Xiuxing, Prager, Briana C., Wu, Qiulian, Kim, Leo J.Y., Gimple, Ryan C., Shi, Yu, Yang, Kailin, Morton, Andrew R., Zhou, Wenchao, Zhu, Zhe, Obara, Elisabeth Anne Adanma, Miller, Tyler E., Song, Anne, Lai, Sisi, Hubert, Christopher G., Jin, Xun, Huang, Zhi, Fang, Xiaoguang, Dixit, Deobrat, Tao, Weiwei, Zhai, Kui, Chen, Cong, Dong, Zhen, Zhang, Guoxin, Dombrowski, Stephen M., Hamerlik, Petra, Mack, Stephen C., Bao, Shideng, Rich, Jeremy N.

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Glioma Stem Cell-Specific Superenhancer Promotes Polyunsaturated Fatty-Acid Synthesis to Support EGFR Signaling von Gimple, Ryan C, Kidwell, Reilly L, Kim, Leo J Y, Sun, Tengqian, Gromovsky, Anthony D, Wu, Qiulian, Wolf, Megan, Lv, Deguan, Bhargava, Shruti, Jiang, Li, Prager, Briana C, Wang, Xiuxing, Ye, Qing, Zhu, Zhe, Zhang, Guoxin, Dong, Zhen, Zhao, Linjie, Lee, Derrick, Bi, Junfeng, Sloan, Andrew E, Mischel, Paul S, Brown, J Mark, Cang, Hu, Huan, Tao, Mack, Stephen C, Xie, Qi, Rich, Jeremy N

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ADAR1-mediated RNA editing links ganglioside catabolism to glioblastoma stem cell maintenance von Jiang, Li, Hao, Yajing, Shao, Changwei, Wu, Qiulian, Prager, Briana C, Gimple, Ryan C, Sulli, Gabriele, Kim, Leo Jy, Zhang, Guoxin, Qiu, Zhixin, Zhu, Zhe, Fu, Xiang-Dong, Rich, Jeremy N

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Superenhancer activation of KLHDC8A drives glioma ciliation and hedgehog signaling von Lee, Derrick, Gimple, Ryan C, Wu, Xujia, Prager, Briana C, Qiu, Zhixin, Wu, Qiulian, Daggubati, Vikas, Mariappan, Aruljothi, Gopalakrishnan, Jay, Sarkisian, Matthew R, Raleigh, David R, Rich, Jeremy N

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Targeting glioblastoma signaling and metabolism with a re-purposed brain-penetrant drug von Bi, Junfeng, Khan, Atif, Tang, Jun, Armando, Aaron M., Wu, Sihan, Zhang, Wei, Gimple, Ryan C., Reed, Alex, Jing, Hui, Koga, Tomoyuki, Wong, Ivy Tsz-Lo, Gu, Yuchao, Miki, Shunichiro, Yang, Huijun, Prager, Briana, Curtis, Ellis J., Wainwright, Derek A., Furnari, Frank B., Rich, Jeremy N., Cloughesy, Timothy F., Kornblum, Harley I., Quehenberger, Oswald, Rzhetsky, Andrey, Cravatt, Benjamin F., Mischel, Paul S.

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LncRNA INHEG promotes glioma stem cell maintenance and tumorigenicity through regulating rRNA 2’-O-methylation von Liu, Lihui, Liu, Ziyang, Liu, Qinghua, Wu, Wei, Lin, Peng, Liu, Xing, Zhang, Yuechuan, Wang, Dongpeng, Prager, Briana C., Gimple, Ryan C., Yu, Jichuan, Zhao, Weixi, Wu, Qiulian, Zhang, Wei, Wu, Erzhong, Chen, Xiaomin, Luo, Jianjun, Rich, Jeremy N., Xie, Qi, Jiang, Tao, Chen, Runsheng

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Editorial: Epigenetic and metabolic regulation of primary and metastatic brain cancers von Gimple, Ryan C., Prager, Briana C., Xie, Qi

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THE PRESENT AND FUTURE OF THE MASS SPECTROMETRY‐BASED INVESTIGATION OF THE EXOSOME LANDSCAPE von Xu, Lian, Gimple, Ryan C., Lau, Wayne Bond, Lau, Bonnie, Fei, Fan, Shen, Qiuhong, Liao, Xiaolin, Li, Yichen, Wang, Wei, He, Ying, Feng, Min, Bu, Hong, Wang, Wei, Zhou, Shengtao

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The Meningioma Enhancer Landscape Delineates Novel Subgroups and Drives Druggable Dependencies von Prager, Briana C, Vasudevan, Harish N, Dixit, Deobrat, Bernatchez, Jean A, Wu, Qiulian, Wallace, Lisa C, Bhargava, Shruti, Lee, Derrick, King, Bradley H, Morton, Andrew R, Gimple, Ryan C, Pekmezci, Melike, Zhu, Zhe, Siqueira-Neto, Jair L, Wang, Xiuxing, Xie, Qi, Chen, Clark, Barnett, Gene H, Vogelbaum, Michael A, Mack, Stephen C, Chavez, Lukas, Perry, Arie, Raleigh, David R, Rich, Jeremy N

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Leveraging Allele-Specific Expression for Therapeutic Response Gene Discovery in Glioblastoma von Sen, Arko, Prager, Briana C, Zhong, Cuiqing, Park, Donglim, Zhu, Zhe, Gimple, Ryan C, Wu, Qiulian, Bernatchez, Jean A, Beck, Sungjun, Clark, Alex E, Siqueira-Neto, Jair L, Rich, Jeremy N, McVicker, Graham

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