The leukemic stem cell niche: current concepts and therapeutic opportunities von Lane, Steven W., Scadden, David T., Gilliland, D. Gary

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Direct inhibition of the NOTCH transcription factor complex von Moellering, Raymond E., Cornejo, Melanie, Davis, Tina N., Bianco, Cristina Del, Aster, Jon C., Blacklow, Stephen C., Kung, Andrew L., Gilliland, D. Gary, Verdine, Gregory L., Bradner, James E.

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FoxO transcription factors and stem cell homeostasis: insights from the hematopoietic system von Tothova, Zuzana, Gilliland, D Gary

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Unifying mechanism for different fibrotic diseases von Wernig, Gerlinde, Chen, Shih-Yu, Cui, Lu, Van Neste, Camille, Tsai, Jonathan M., Kambham, Neeraja, Vogel, Hannes, Natkunam, Yaso, Gilliland, D. Gary, Nolan, Garry, Weissman, Irving L.

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Integrated genomic analysis illustrates the central role of JAK-STAT pathway activation in myeloproliferative neoplasm pathogenesis von Rampal, Raajit, Al-Shahrour, Fatima, Abdel-Wahab, Omar, Patel, Jay P., Brunel, Jean-Philippe, Mermel, Craig H., Bass, Adam J., Pretz, Jennifer, Ahn, Jihae, Hricik, Todd, Kilpivaara, Outi, Wadleigh, Martha, Busque, Lambert, Gilliland, D. Gary, Golub, Todd R., Ebert, Benjamin L., Levine, Ross L.

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Myeloproliferative disorders von Levine, Ross L., Gilliland, D. Gary

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Runx1 Deficiency Decreases Ribosome Biogenesis and Confers Stress Resistance to Hematopoietic Stem and Progenitor Cells von Cai, Xiongwei, Gao, Long, Teng, Li, Ge, Jingping, Oo, Zaw Min, Kumar, Ashish R., Gilliland, D. Gary, Mason, Philip J., Tan, Kai, Speck, Nancy A.

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Role of JAK2 in the pathogenesis and therapy of myeloproliferative disorders von Tefferi, Ayalew, Gilliland, D. Gary, Levine, Ross L, Pardanani, Animesh

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The roles of FLT3 in hematopoiesis and leukemia von Gilliland, D. Gary, Griffin, James D.

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The interferon-stimulated gene RIPK1 regulates cancer cell intrinsic and extrinsic resistance to immune checkpoint blockade von Cucolo, Lisa, Chen, Qingzhou, Qiu, Jingya, Yu, Yongjun, Klapholz, Max, Budinich, Krista A, Zhang, Zhaojun, Shao, Yue, Brodsky, Igor E, Jordan, Martha S, Gilliland, D Gary, Zhang, Nancy R, Shi, Junwei, Minn, Andy J

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Phase IIB Trial of Oral Midostaurin (PKC412), the FMS-Like Tyrosine Kinase 3 Receptor (FLT3) and Multi-Targeted Kinase Inhibitor, in Patients With Acute Myeloid Leukemia and High-R... von FISCHER, Thomas, STONE, Richard M, KLIMEK, Virginia M, NIMER, Stephen D, GILLILAND, D. Gary, DUTREIX, Catherine, HUNTSMAN-LABED, Alice, VIRKUS, Jodi, GILES, Francis J, DEANGELO, Daniel J, GALINSKY, Ilene, ESTEY, Elihu, LANZA, Carlo, FOX, Edward, EHNINGER, Gerhard, FELDMAN, Eric J, SCHILLER, Gary J

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Safety and Efficacy of TG101348, a Selective JAK2 Inhibitor, in Myelofibrosis von PARDANANI, Animesh, GOTLIB, Jason R, JAMIESON, Catriona, CORTES, Jorge E, TALPAZ, Moshe, STONE, Richard M, SILVERMAN, Michael H, GILLILAND, D. Gary, SHORR, Jolene, TEFFERI, Ayalew

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FoxOs Are Critical Mediators of Hematopoietic Stem Cell Resistance to Physiologic Oxidative Stress von Tothova, Zuzana, Kollipara, Ramya, Huntly, Brian J., Lee, Benjamin H., Castrillon, Diego H., Cullen, Dana E., McDowell, Elizabeth P., Lazo-Kallanian, Suzan, Williams, Ifor R., Sears, Christopher, Armstrong, Scott A., Passegué, Emmanuelle, DePinho, Ronald A., Gilliland, D. Gary

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Differential niche and Wnt requirements during acute myeloid leukemia progression von Lane, Steven W., Wang, Yingzi J., Lo Celso, Cristina, Ragu, Christine, Bullinger, Lars, Sykes, Stephen M., Ferraro, Francesca, Shterental, Sebastian, Lin, Charles P., Gilliland, D. Gary, Scadden, David T., Armstrong, Scott A., Williams, David A.

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Constitutively active AKT depletes hematopoietic stem cells and induces leukemia in mice von Kharas, Michael G., Okabe, Rachel, Ganis, Jared J., Gozo, Maricel, Khandan, Tulasi, Paktinat, Mahnaz, Gilliland, D. Gary, Gritsman, Kira

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Genetic characterization of TET1, TET2, and TET3 alterations in myeloid malignancies von Abdel-Wahab, Omar, Mullally, Ann, Hedvat, Cyrus, Garcia-Manero, Guillermo, Patel, Jay, Wadleigh, Martha, Malinge, Sebastien, Yao, JinJuan, Kilpivaara, Outi, Bhat, Rukhmi, Huberman, Kety, Thomas, Sabrena, Dolgalev, Igor, Heguy, Adriana, Paietta, Elisabeth, Le Beau, Michelle M., Beran, Miloslav, Tallman, Martin S., Ebert, Benjamin L., Kantarjian, Hagop M., Stone, Richard M., Gilliland, D. Gary, Crispino, John D., Levine, Ross L.

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Oncogenes in Myeloproliferative Disorders von Tefferi, Ayalew, Gilliland, D. Gary

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Drug therapy for acute myeloid leukemia von Tallman, Martin S., Gilliland, D. Gary, Rowe, Jacob M.

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Proposals and rationale for revision of the World Health Organization diagnostic criteria for polycythemia vera, essential thrombocythemia, and primary myelofibrosis: recommendatio... von Tefferi, Ayalew, Thiele, Juergen, Orazi, Attilio, Kvasnicka, Hans Michael, Barbui, Tiziano, Hanson, Curtis A., Barosi, Giovanni, Verstovsek, Srdan, Birgegard, Gunnar, Mesa, Ruben, Reilly, John T., Gisslinger, Heinz, Vannucchi, Alessandro M., Cervantes, Francisco, Finazzi, Guido, Hoffman, Ronald, Gilliland, D. Gary, Bloomfield, Clara D., Vardiman, James W.

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Preclinical evaluation of the WEE1 inhibitor MK-1775 as single-agent anticancer therapy von Guertin, Amy D, Li, Jing, Liu, Yaping, Hurd, Melissa S, Schuller, Alwin G, Long, Brian, Hirsch, Heather A, Feldman, Igor, Benita, Yair, Toniatti, Carlo, Zawel, Leigh, Fawell, Stephen E, Gilliland, D Gary, Shumway, Stuart D

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