Endogenous Nmnat2 is an essential survival factor for maintenance of healthy axons von Gilley, Jonathan, Coleman, Michael P

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Absence of SARM1 Rescues Development and Survival of NMNAT2-Deficient Axons von Gilley, Jonathan, Orsomando, Giuseppe, Nascimento-Ferreira, Isabel, Coleman, Michael P.

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Low levels of NMNAT2 compromise axon development and survival von Gilley, Jonathan, Mayer, Paul R, Yu, Gang, Coleman, Michael P

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NAD + cleavage activity by animal and plant TIR domains in cell death pathways von Horsefield, Shane, Burdett, Hayden, Zhang, Xiaoxiao, Manik, Mohammad K, Shi, Yun, Chen, Jian, Qi, Tiancong, Gilley, Jonathan, Lai, Jhih-Siang, Rank, Maxwell X, Casey, Lachlan W, Gu, Weixi, Ericsson, Daniel J, Foley, Gabriel, Hughes, Robert O, Bosanac, Todd, von Itzstein, Mark, Rathjen, John P, Nanson, Jeffrey D, Boden, Mikael, Dry, Ian B, Williams, Simon J, Staskawicz, Brian J, Coleman, Michael P, Ve, Thomas, Dodds, Peter N, Kobe, Bostjan

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Mitochondrial impairment activates the Wallerian pathway through depletion of NMNAT2 leading to SARM1-dependent axon degeneration von Loreto, Andrea, Hill, Ciaran S., Hewitt, Victoria L., Orsomando, Giuseppe, Angeletti, Carlo, Gilley, Jonathan, Lucci, Cristiano, Sanchez-Martinez, Alvaro, Whitworth, Alexander J., Conforti, Laura, Dajas-Bailador, Federico, Coleman, Michael P.

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Rescue of peripheral and CNS axon defects in mice lacking NMNAT2 von Gilley, Jonathan, Adalbert, Robert, Yu, Gang, Coleman, Michael P

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Subcellular localization determines the stability and axon protective capacity of axon survival factor Nmnat2 von Milde, Stefan, Gilley, Jonathan, Coleman, Michael P

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FOXO Transcription Factors Directly Activate bim Gene Expression and Promote Apoptosis in Sympathetic Neurons von Gilley, Jonathan, Coffer, Paul J., Ham, Jonathan

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Adaptation of a Commercial NAD + Quantification Kit to Assay the Base-Exchange Activity and Substrate Preferences of SARM1 von Cirilli, Ilenia, Amici, Adolfo, Gilley, Jonathan, Coleman, Michael P, Orsomando, Giuseppe

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Sarm1 haploinsufficiency or low expression levels after antisense oligonucleotides delay programmed axon degeneration von Gould, Stacey Anne, Gilley, Jonathan, Ling, Karen, Jafar-Nejad, Paymaan, Rigo, Frank, Coleman, Michael

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Natural variants of human SARM1 cause both intrinsic and dominant loss-of-function influencing axon survival von Ademi, Mirlinda, Yang, Xiuna, Coleman, Michael P., Gilley, Jonathan

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NMNAT2 is a druggable target to drive neuronal NAD production von Tribble, James R., Jöe, Melissa, Varricchio, Carmine, Otmani, Amin, Canovai, Alessio, Habchi, Baninia, Daskalakis, Evangelia, Chaleckis, Romanas, Loreto, Andrea, Gilley, Jonathan, Wheelock, Craig E., Jóhannesson, Gauti, Wong, Raymond C. B., Coleman, Michael P., Brancale, Andrea, Williams, Pete A.

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SARM1 is a multi-functional NAD(P)ase with prominent base exchange activity, all regulated bymultiple physiologically relevant NAD metabolites von Angeletti, Carlo, Amici, Adolfo, Gilley, Jonathan, Loreto, Andrea, Trapanotto, Antonio G., Antoniou, Christina, Merlini, Elisa, Coleman, Michael P., Orsomando, Giuseppe

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Author Correction: NMNAT2 is a druggable target to drive neuronal NAD production von Tribble, James R., Jöe, Melissa, Varricchio, Carmine, Otmani, Amin, Canovai, Alessio, Habchi, Baninia, Daskalakis, Evangelia, Chaleckis, Romanas, Loreto, Andrea, Gilley, Jonathan, Wheelock, Craig E., Jóhannesson, Gauti, Wong, Raymond C. B., Coleman, Michael P., Brancale, Andrea, Williams, Pete A.

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Enrichment of SARM1 alleles encoding variants with constitutively hyperactive NADase in patients with ALS and other motor nerve disorders von Gilley, Jonathan, Jackson, Oscar, Pipis, Menelaos, Estiar, Mehrdad A, Al-Chalabi, Ammar, Danzi, Matt C, van Eijk, Kristel R, Goutman, Stephen A, Harms, Matthew B, Houlden, Henry, Iacoangeli, Alfredo, Kaye, Julia, Lima, Leandro, Ravits, John, Rouleau, Guy A, Schüle, Rebecca, Xu, Jishu, Züchner, Stephan, Cooper-Knock, Johnathan, Gan-Or, Ziv, Reilly, Mary M, Coleman, Michael P

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Neurotoxin-mediated potent activation of the axon degeneration regulator SARM1 von Loreto, Andrea, Angeletti, Carlo, Gu, Weixi, Osborne, Andrew, Nieuwenhuis, Bart, Gilley, Jonathan, Merlini, Elisa, Arthur-Farraj, Peter, Amici, Adolfo, Luo, Zhenyao, Hartley-Tassell, Lauren, Ve, Thomas, Desrochers, Laura M, Wang, Qi, Kobe, Bostjan, Orsomando, Giuseppe, Coleman, Michael P

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Reduced number of axonal mitochondria and tau hypophosphorylation in mouse P301L tau knockin neurons von Rodríguez-Martín, Teresa, Pooler, Amy M, Lau, Dawn H.W, Mórotz, Gábor M, De Vos, Kurt J, Gilley, Jonathan, Coleman, Michael P, Hanger, Diane P

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Difference Tracker: ImageJ plugins for fully automated analysis of multiple axonal transport parameters von Andrews, Simon, Gilley, Jonathan, Coleman, Michael P.

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NMNAT2 supports vesicular glycolysis via NAD homeostasis to fuel fast axonal transport von Yang, Sen, Niou, Zhen-Xian, Enriquez, Andrea, LaMar, Jacob, Huang, Jui-Yen, Ling, Karen, Jafar-Nejad, Paymaan, Gilley, Jonathan, Coleman, Michael P, Tennessen, Jason M, Rangaraju, Vidhya, Lu, Hui-Chen

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The NAD + precursor NMN activates dSarm to trigger axon degeneration in Drosophila von Llobet Rosell, Arnau, Paglione, Maria, Gilley, Jonathan, Kocia, Magdalena, Perillo, Giulia, Gasparrini, Massimiliano, Cialabrini, Lucia, Raffaelli, Nadia, Angeletti, Carlo, Orsomando, Giuseppe, Wu, Pei-Hsuan, Coleman, Michael P, Loreto, Andrea, Neukomm, Lukas Jakob

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