A human antibody directed to the factor VIII C1 domain inhibits factor VIII cofactor activity and binding to von Willebrand factor von JACQUEMIN, M, BENHIDA, A, GILLES, J.-G, VERMYLEN, J, SAINT-REMY, J.-M, PEERLINCK, K, DESQUEPER, B, ELST, L. V, LAVEND'HOMME, R, D'OIRON, R, SCHWAAB, R, BAKKUS, M, THIELEMANS, K

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Anti-heavy-chain monoclonal antibodies directed to the acidic regions of the factor VIII molecule inhibit the binding of factor VIII to phospholipids and von Willebrand factor von Raut, Sanjeev, Villard, Sylvie, Grailly, Sabrina, Gilles, Jean-Guy G., Granier, Claude, Saint-Remy, Jean-Marie R., Barrowcliffe, Trevor W.

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In vivo neutralization of a C2 domain–specific human anti–Factor VIII inhibitor by an anti-idiotypic antibody von Gilles, Jean Guy G., Grailly, Sabrina C., De Maeyer, Marc, Jacquemin, Marc G., VanderElst, Luc P., Saint-Remy, Jean-Marie R.

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Humanized Severe Combined Immunodeficient Mice as a Potential Model for the Study of Tolerance to Factor VIII von Vanzieleghem, Beatrijs, Gilles, Jean Guy, Desqueper, Benoît, Vermylen, Jos, Saint-Remy, Jean-Marie

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Mechanism and Kinetics of Factor VIII Inactivation: Study With an IgG4 Monoclonal Antibody Derived From a Hemophilia A Patient With Inhibitor von Jacquemin, Marc G., Desqueper, Benoı̂t G., Benhida, Abdellah, Vander Elst, Luc, Hoylaerts, Marc F., Bakkus, Marleen, Thielemans, Kris, Arnout, Jef, Peerlinck, Kathelijne, Gilles, Jean Guy G., Vermylen, Jos, Saint-Remy, Jean-Marie R.

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Mechanism and Kinetics of Factor VIII Inactivation: Study With an IgG4 Monoclonal Antibody Derived From a Hemophilia A Patient With Inhibitor von Jacquemin, Marc G., Desqueper, Benoı̂t G., Benhida, Abdellah, Vander Elst, Luc, Hoylaerts, Marc F., Bakkus, Marleen, Thielemans, Kris, Arnout, Jef, Peerlinck, Kathelijne, Gilles, Jean Guy G., Vermylen, Jos, Saint-Remy, Jean-Marie R.

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A novel cause of mild/moderate hemophilia A: mutations scattered in the factor VIII C1 domain reduce factor VIII binding to von Willebrand factor von Jacquemin, Marc, Lavend'homme, Renaud, Benhida, Abdellah, Vanzieleghem, Beatrijs, d'Oiron, Roseline, Lavergne, Jean-Maurice, Brackmann, Hans H., Schwaab, Rainer, VandenDriessche, Thierry, Chuah, Marinee K. L., Hoylaerts, Marc, Gilles, Jean Guy G., Peerlinck, Kathelijne, Vermylen, Jos, Saint-Remy, Jean-Marie R.

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A Limited Number of Anti-Idiotypic Antibodies Is Required To Maintain FVIII Function in Presence of Polyclonal Anti-FVIII Antibodies of Haemophilia A Patients with Inhibitors von Gilles, Jean Guy G., Grailly, Sabrina E., Jacquemin, Marc G., Saint-Remy, Jean Marie M.

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Healthy subjects produce both anti-factor VIII and specific anti-idiotypic antibodies von Gilles, J G, Saint-Remy, J M

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Antifactor VIII Antibody Inhibiting Allogeneic but not Autologous Factor VIII in Patients With Mild Hemophilia A von Peerlinck, Kathelijne, Jacquemin, Marc G., Arnout, Jef, Hoylaerts, Marc F., Gilles, Jean Guy G., Lavend’homme, Renaud, Johnson, Karen M., Freson, Kathleen, Scandella, Dorothea, Saint-Remy, Jean-Marie R., Vermylen, Jos

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Anti-Factor VIII Antibodies of Hemophiliac Patients Are Frequently Directed Towards Nonfunctional Determinants and Do Not Exhibit Isotypic Restriction von Gilles, Jean Guy G., Arnout, Jef, Vermylen, Jos, Saint-Remy, Jean-Marie R.

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Neutralizing antiidiotypic antibodies to factor VIII inhibitors after desensitization in patients with hemophilia A von Gilles, J G, Desqueper, B, Lenk, H, Vermylen, J, Saint-Remy, J M

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In vivo neutralization of a C2 domain-specific human anti-Factor VIII inhibitor by an anti-idiotypic antibody von Gilles, Jean Guy, Grailly, Sabrina, De Maeyer, Marc, Jacquemin, Marc, VanderElst, Luc P, Saint-Remy, Jean-Marie

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Natural Autoantibodies and Anti-Idiotypes von Gilles, Jean Guy G., Vanzieleghem, Beatrüs, Saint-Remy, Jean-Marie R.

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A novel cause of mild/moderate hemophilia A : mutations scattered in the factor VIII C1 domain reduce factor VIII binding to von Willebrand factor von JACQUEMIN, M, LAVEND'HOMME, R, HOYLAERTS, M, GILLES, J. G. G, PEERLINCK, K, VERMYLEN, J, SAINT-REMY, J.-M. R, BENHIDA, A, VANZIELEGHEM, B, D'OIRON, R, LAVERGNE, J.-M, BRACKMANN, H. H, SCHWAAB, R, VANDENDRIESSCHE, T, CHUAH, M. K. L

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Anti‐ldiotypic Antibodies: From Regulation to Therapy of Factor VIII Inhibitors von Saint‐Remy, Jean‐Marie R., Jacquemin, Marc G., Gilles, Jean Guy

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A human antibody directed to the factor VIII C1 domain inhibits factor VIII cofactor activity and binding to von Willebrand factor von Jacquemin, Marc, Benhida, Abdellah, Peerlinck, Kathelijne, Desqueper, Benoı̂t, Vander Elst, Luc, Lavend'homme, Renaud, d'Oiron, Roseline, Schwaab, Rainer, Bakkus, Marleen, Thielemans, Kris, Gilles, Jean-Guy, Vermylen, Jos, Saint-Remy, Jean-Marie

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Antifactor VIII Antibody Inhibiting Allogeneic but not Autologous Factor VIII in Patients With Mild Hemophilia A von Peerlinck, Kathelijne, Jacquemin, Marc G., Arnout, Jef, Hoylaerts, Marc F., Gilles, Jean Guy G., Lavend'homme, Renaud, Johnson, Karen M., Freson, Kathleen, Scandella, Dorothea, Saint-Remy, Jean-Marie R., Vermylen, Jos

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Anti–Idiotypic Antibodies: From Regulation to Therapy of Factor VIII Inhibitors von Saint-Remy, Jean-Marie R., Jacquemin, Marc G., Gilles, Jean Guy

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Animal models to explore mechanisms of tolerance induction to FVIII : SCID mice and SCID-FVIII-KO mice. Discussion von GILLES, Jean Guy, VANZIELEGHEM, Beatrijs, SAINT-REMY, Jean-Marie, HOYER, GILLES, KAZATCHKINE, EWENSTEIN, RYPERT

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