Genetic variation in metabolic phenotypes: study designs and applications von Suhre, Karsten, Gieger, Christian

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Tobacco smoking leads to extensive genome-wide changes in DNA methylation von Zeilinger, Sonja, Kühnel, Brigitte, Klopp, Norman, Baurecht, Hansjörg, Kleinschmidt, Anja, Gieger, Christian, Weidinger, Stephan, Lattka, Eva, Adamski, Jerzy, Peters, Annette, Strauch, Konstantin, Waldenberger, Melanie, Illig, Thomas

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Connecting genetic risk to disease end points through the human blood plasma proteome von Suhre, Karsten, Arnold, Matthias, Bhagwat, Aditya Mukund, Cotton, Richard J., Engelke, Rudolf, Raffler, Johannes, Sarwath, Hina, Thareja, Gaurav, Wahl, Annika, DeLisle, Robert Kirk, Gold, Larry, Pezer, Marija, Lauc, Gordan, El-Din Selim, Mohammed A., Mook-Kanamori, Dennis O., Al-Dous, Eman K., Mohamoud, Yasmin A., Malek, Joel, Strauch, Konstantin, Grallert, Harald, Peters, Annette, Kastenmüller, Gabi, Gieger, Christian, Graumann, Johannes

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Genome‐wide mapping of plasma protein QTLs identifies putatively causal genes and pathways for cardiovascular disease von Yao, Chen, Chen, George, Song, Ci, Keefe, Joshua, Mendelson, Michael, Huan, Tianxiao, Sun, Benjamin B., Laser, Annika, Maranville, Joseph C., Wu, Hongsheng, Ho, Jennifer E., Courchesne, Paul, Lyass, Asya, Larson, Martin G., Gieger, Christian, Graumann, Johannes, Johnson, Andrew D., Danesh, John, Runz, Heiko, Hwang, Shih-Jen, Liu, Chunyu, Butterworth, Adam S., Suhre, Karsten, Levy, Daniel

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DNA methylation and body-mass index: a genome-wide analysis von Dick, Katherine J, PhD, Nelson, Christopher P, PhD, Tsaprouni, Loukia, PhD, Sandling, Johanna K, PhD, Aïssi, Dylan, MSc, Wahl, Simone, MSc, Meduri, Eshwar, PhD, Morange, Pierre-Emmanuel, Prof, Gagnon, France, PhD, Grallert, Harald, PhD, Waldenberger, Melanie, PhD, Peters, Annette, Prof, Erdmann, Jeanette, Prof, Hengstenberg, Christian, Prof, Cambien, Francois, Prof, Goodall, Alison H, Prof, Ouwehand, Willem H, Prof, Schunkert, Heribert, Prof, Thompson, John R, Prof, Spector, Tim D, FRCP, Gieger, Christian, PhD, Trégouët, David-Alexandre, PhD, Deloukas, Panos, Prof, Samani, Nilesh J, Prof

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Serum metabolic signatures of coronary and carotid atherosclerosis and subsequent cardiovascular disease von Tzoulaki, Ioanna, Castagné, Raphaële, Boulangé, Claire L, Karaman, Ibrahim, Chekmeneva, Elena, Evangelou, Evangelos, Ebbels, Timothy M D, Kaluarachchi, Manuja R, Chadeau-Hyam, Marc, Mosen, David, Dehghan, Abbas, Moayyeri, Alireza, Ferreira, Diana L Santos, Guo, Xiuqing, Rotter, Jerome I, Taylor, Kent D, Kavousi, Maryam, de Vries, Paul S, Lehne, Benjamin, Loh, Marie, Hofman, Albert, Nicholson, Jeremy K, Chambers, John, Gieger, Christian, Holmes, Elaine, Tracy, Russell, Kooner, Jaspal, Greenland, Philip, Franco, Oscar H, Herrington, David, Lindon, John C, Elliott, Paul

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Characterization of missing values in untargeted MS-based metabolomics data and evaluation of missing data handling strategies von Do, Kieu Trinh, Wahl, Simone, Raffler, Johannes, Molnos, Sophie, Laimighofer, Michael, Adamski, Jerzy, Suhre, Karsten, Strauch, Konstantin, Peters, Annette, Gieger, Christian, Langenberg, Claudia, Stewart, Isobel D., Theis, Fabian J., Grallert, Harald, Kastenmüller, Gabi, Krumsiek, Jan

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Revealing the role of the human blood plasma proteome in obesity using genetic drivers von Zaghlool, Shaza B., Sharma, Sapna, Molnar, Megan, Matías-García, Pamela R., Elhadad, Mohamed A., Waldenberger, Melanie, Peters, Annette, Rathmann, Wolfgang, Graumann, Johannes, Gieger, Christian, Grallert, Harald, Suhre, Karsten

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Impact of long-term storage and freeze-thawing on eight circulating microRNAs in plasma samples von Matias-Garcia, Pamela R., Wilson, Rory, Mussack, Veronika, Reischl, Eva, Waldenberger, Melanie, Gieger, Christian, Anton, Gabriele, Peters, Annette, Kuehn-Steven, Andrea

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A Metabolome-Wide Association Study of Kidney Function and Disease in the General Population von Sekula, Peggy, Goek, Oemer-Necmi, Quaye, Lydia, Barrios, Clara, Levey, Andrew S, Römisch-Margl, Werner, Menni, Cristina, Yet, Idil, Gieger, Christian, Inker, Lesley A, Adamski, Jerzy, Gronwald, Wolfram, Illig, Thomas, Dettmer, Katja, Krumsiek, Jan, Oefner, Peter J, Valdes, Ana M, Meisinger, Christa, Coresh, Josef, Spector, Tim D, Mohney, Robert P, Suhre, Karsten, Kastenmüller, Gabi, Köttgen, Anna

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Epigenome-wide association of DNA methylation markers in peripheral blood from Indian Asians and Europeans with incident type 2 diabetes: a nested case-control study von Chambers, John C, Dr, Loh, Marie, PhD, Lehne, Benjamin, PhD, Drong, Alexander, PhD, Kriebel, Jennifer, PhD, Motta, Valeria, PhD, Wahl, Simone, MSc, Elliott, Hannah R, Dip Biol, Rota, Federica, PhD, Scott, William R, MRCP, Zhang, Weihua, PhD, Tan, Sian-Tsung, MRCP, Campanella, Gianluca, MSc, Chadeau-Hyam, Marc, PhD, Yengo, Loic, PhD, Richmond, Rebecca C, BA, Adamowicz-Brice, Martyna, PhD, Afzal, Uzma, MRCP, Bozaoglu, Kiymet, PhD, Mok, Zuan Yu, BSc, Ng, Hong Kiat, BSc, Pattou, François, Prof, Prokisch, Holger, PhD, Rozario, Michelle Ann, BSc, Tarantini, Letizia, PhD, Abbott, James, PhD, Ala-Korpela, Mika, Prof, Albetti, Benedetta, PhD, Ammerpohl, Ole, Prof, Bertazzi, Pier Alberto, Prof, Blancher, Christine, PhD, Caiazzo, Robert, PhD, Danesh, John, Prof, Gaunt, Tom R, FRCP, de Lusignan, Simon, Prof, Gieger, Christian, PhD, Illig, Thomas, Prof, Jha, Sujeet, MRCP, Jones, Simon, Prof, Jowett, Jeremy, PhD, Kangas, Antti J, MSc, Kasturiratne, Anuradhani, MD, Kato, Norihiro, PhD, Kotea, Navaratnam, PhD, Kowlessur, Sudhir, Dip Pub Health Admin, Pitkäniemi, Janne, PhD, Punjabi, Prakash, FRCS, Saleheen, Danish, PhD, Schafmayer, Clemens, Prof, Soininen, Pasi, PhD, Tai, E-Shyong, PhD, Thorand, Barbara, PhD, Tuomilehto, Jaakko, Prof, Wickremasinghe, Ananda Rajitha, Prof, Kyrtopoulos, Soterios A, Prof, Aitman, Timothy J, Prof, Herder, Christian, PhD, Hampe, Jochen, Prof, Cauchi, Stéphane, PhD, Relton, Caroline L, Prof, Froguel, Philippe, Prof, Soong, Richie, PhD, Vineis, Paolo, Prof, Jarvelin, Marjo-Riitta, Prof, Scott, James, Prof, Grallert, Harald, PhD, Bollati, Valentina, PhD, Elliott, Paul, Prof, McCarthy, Mark I, Prof, Kooner, Jaspal S, Prof

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Biomarkers for Type 2 Diabetes and Impaired Fasting Glucose Using a Nontargeted Metabolomics Approach von MENNI, Cristina, FAUMAN, Eric, WEI YUAN, MILBURN, Mike, PALMER, Colin N. A, FRAYLING, Timothy M, TRIMMER, Jeff, BELL, Jordana T, GIEGER, Christian, MOHNEY, Rob P, BROSNAN, Mary Julia, SUHRE, Karsten, ERTE, Idil, SORANZO, Nicole, SPECTOR, Tim D, PERRY, John R. B, KASTENMÜLLER, Gabi, SHIN, So-Youn, PETERSEN, Ann-Kristin, HYDE, Craig, PSATHA, Maria, WARD, Kirsten J

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A genome-wide association meta-analysis on lipoprotein (a) concentrations adjusted for apolipoprotein (a) isoforms[S] von Mack, Salome, Coassin, Stefan, Rueedi, Rico, Yousri, Noha A., Seppälä, Ilkka, Gieger, Christian, Schönherr, Sebastian, Forer, Lukas, Erhart, Gertraud, Marques-Vidal, Pedro, Ried, Janina S., Waeber, Gerard, Bergmann, Sven, Dähnhardt, Doreen, Stöckl, Andrea, Raitakari, Olli T., Kähönen, Mika, Peters, Annette, Meitinger, Thomas, Strauch, Konstantin, Kedenko, Ludmilla, Paulweber, Bernhard, Lehtimäki, Terho, Hunt, Steven C., Vollenweider, Peter, Lamina, Claudia, Kronenberg, Florian

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A polygenic and family risk score are both independently associated with risk of type 2 diabetes in a population-based study von Duschek, Elena, Forer, Lukas, Schönherr, Sebastian, Gieger, Christian, Peters, Annette, Kronenberg, Florian, Grallert, Harald, Lamina, Claudia

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A genome-wide association study of plasma total IgE concentrations in the Framingham Heart Study von Granada, Mark, MD, Wilk, Jemma B., DSc, Tuzova, Marina, MD, PhD, Strachan, David P., MD, Weidinger, Stephan, MD, Albrecht, Eva, MSc, Gieger, Christian, PhD, Heinrich, Joachim, PhD, Himes, Blanca E., PhD, Hunninghake, Gary M., MD, MPH, Celedón, Juan C., MD, DrPH, Weiss, Scott T., MD, Cruikshank, William W., PhD, Farrer, Lindsay A., PhD, Center, David M., MD, O'Connor, George T., MD, MS

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Metabolic footprint of diabetes: a multiplatform metabolomics study in an epidemiological setting von Suhre, Karsten, Meisinger, Christa, Döring, Angela, Altmaier, Elisabeth, Belcredi, Petra, Gieger, Christian, Chang, David, Milburn, Michael V, Gall, Walter E, Weinberger, Klaus M, Mewes, Hans-Werner, Hrabé de Angelis, Martin, Wichmann, H-Erich, Kronenberg, Florian, Adamski, Jerzy, Illig, Thomas

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Atopic dermatitis is associated with an increased risk for rheumatoid arthritis and inflammatory bowel disease, and a decreased risk for type 1 diabetes von Schmitt, Jochen, MD, MPH, Schwarz, Kristin, MSc, Baurecht, Hansjörg, MSc, Hotze, Melanie, MSc, Fölster-Holst, Regina, MD, Rodríguez, Elke, PhD, Lee, Young A.E., MD, Franke, Andre, PhD, Degenhardt, Frauke, MSc, Lieb, Wolfgang, PhD, Gieger, Christian, PhD, Kabesch, Michael, MD, Nöthen, Markus M., MD, Irvine, Alan D., MD, McLean, W.H. Irwin, PhD, Deckert, Stefanie, MPH, Stephan, Victoria, Schwarz, Peter, MD, Aringer, Martin, MD, Novak, Natalija, MD, Weidinger, Stephan, MD, MaHM

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Human serum metabolic profiles are age dependent von Yu, Zhonghao, Zhai, Guangju, Singmann, Paula, He, Ying, Xu, Tao, Prehn, Cornelia, Römisch‐Margl, Werner, Lattka, Eva, Gieger, Christian, Soranzo, Nicole, Heinrich, Joachim, Standl, Marie, Thiering, Elisabeth, Mittelstraß, Kirstin, Wichmann, Heinz‐Erich, Peters, Annette, Suhre, Karsten, Li, Yixue, Adamski, Jerzy, Spector, Tim D., Illig, Thomas, Wang‐Sattler, Rui

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Discovery of sexual dimorphisms in metabolic and genetic biomarkers von Mittelstrass, Kirstin, Ried, Janina S, Yu, Zhonghao, Krumsiek, Jan, Gieger, Christian, Prehn, Cornelia, Roemisch-Margl, Werner, Polonikov, Alexey, Peters, Annette, Theis, Fabian J, Meitinger, Thomas, Kronenberg, Florian, Weidinger, Stephan, Wichmann, Heinz Erich, Suhre, Karsten, Wang-Sattler, Rui, Adamski, Jerzy, Illig, Thomas

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The dynamics of smoking-related disturbed methylation: a two time-point study of methylation change in smokers, non-smokers and former smokers von Wilson, Rory, Wahl, Simone, Pfeiffer, Liliane, Ward-Caviness, Cavin K, Kunze, Sonja, Kretschmer, Anja, Reischl, Eva, Peters, Annette, Gieger, Christian, Waldenberger, Melanie

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