Two Phase 3 Trials of Dupilumab versus Placebo in Atopic Dermatitis von Simpson, Eric L, Bieber, Thomas, Guttman-Yassky, Emma, Beck, Lisa A, Blauvelt, Andrew, Cork, Michael J, Silverberg, Jonathan I, Deleuran, Mette, Kataoka, Yoko, Lacour, Jean-Philippe, Kingo, Külli, Worm, Margitta, Poulin, Yves, Wollenberg, Andreas, Soo, Yuhwen, Graham, Neil M.H, Pirozzi, Gianluca, Akinlade, Bolanle, Staudinger, Heribert, Mastey, Vera, Eckert, Laurent, Gadkari, Abhijit, Stahl, Neil, Yancopoulos, George D, Ardeleanu, Marius

Volltext

Patient burden of moderate to severe atopic dermatitis (AD): Insights from a phase 2b clinical trial of dupilumab in adults von Simpson, Eric L., MD, MCR, Bieber, Thomas, MD, Eckert, Laurent, PhD, Wu, Richard, PhD, Ardeleanu, Marius, MD, Graham, Neil M.H., MD, Pirozzi, Gianluca, MD, PhD, Mastey, Vera, MSc

Volltext

Dupilumab in Persistent Asthma with Elevated Eosinophil Levels von Wenzel, Sally, Ford, Linda, Pearlman, David, Spector, Sheldon, Sher, Lawrence, Skobieranda, Franck, Wang, Lin, Kirkesseli, Stephane, Rocklin, Ross, Bock, Brian, Hamilton, Jennifer, Ming, Jeffrey E, Radin, Allen, Stahl, Neil, Yancopoulos, George D, Graham, Neil, Pirozzi, Gianluca

Volltext

Efficacy and Safety of Dupilumab in Glucocorticoid-Dependent Severe Asthma von Rabe, Klaus F, Nair, Parameswaran, Brusselle, Guy, Maspero, Jorge F, Castro, Mario, Sher, Lawrence, Zhu, Hongjie, Hamilton, Jennifer D, Swanson, Brian N, Khan, Asif, Chao, Jingdong, Staudinger, Heribert, Pirozzi, Gianluca, Antoni, Christian, Amin, Nikhil, Ruddy, Marcella, Akinlade, Bolanle, Graham, Neil M.H, Stahl, Neil, Yancopoulos, George D, Teper, Ariel

Volltext

Dupilumab Treatment in Adults with Moderate-to-Severe Atopic Dermatitis von Beck, Lisa A, Thaçi, Diamant, Hamilton, Jennifer D, Graham, Neil M, Bieber, Thomas, Rocklin, Ross, Ming, Jeffrey E, Ren, Haobo, Kao, Richard, Simpson, Eric, Ardeleanu, Marius, Weinstein, Steven P, Pirozzi, Gianluca, Guttman-Yassky, Emma, Suárez-Fariñas, Mayte, Hager, Melissa D, Stahl, Neil, Yancopoulos, George D, Radin, Allen R

Volltext

Dupilumab efficacy and safety in adults with uncontrolled persistent asthma despite use of medium-to-high-dose inhaled corticosteroids plus a long-acting β2 agonist: a randomised d... von Wenzel, Sally, Prof, Castro, Mario, MD, Corren, Jonathan, MD, Maspero, Jorge, MD, Wang, Lin, PhD, Zhang, Bingzhi, PhD, Pirozzi, Gianluca, MD, Sutherland, E Rand, MD, Evans, Robert R, PharmD, Joish, Vijay N, PhD, Eckert, Laurent, PhD, Graham, Neil M H, MD, Stahl, Neil, PhD, Yancopoulos, George D, MD, Louis-Tisserand, Mariana, MD, Teper, Ariel, MD

Volltext

Efficacy and safety of dupilumab monotherapy in adults with moderate-to-severe atopic dermatitis: a pooled analysis of two phase 3 randomized trials (LIBERTY AD SOLO 1 and LIBERTY... von Thaçi, Diamant, L. Simpson, Eric, Deleuran, Mette, Kataoka, Yoko, Chen, Zhen, Gadkari, Abhijit, Eckert, Laurent, Akinlade, Bolanle, Graham, Neil M.H., Pirozzi, Gianluca, Ardeleanu, Marius

Volltext

Dupilumab suppresses type 2 inflammatory biomarkers across multiple atopic, allergic diseases von Hamilton, Jennifer D., Harel, Sivan, Swanson, Brian N., Brian, William, Chen, Zhen, Rice, Megan S., Amin, Nikhil, Ardeleanu, Marius, Radin, Allen, Shumel, Brad, Ruddy, Marcella, Patel, Naimish, Pirozzi, Gianluca, Mannent, Leda, Graham, Neil M. H.

Volltext

Efficacy and safety of dupilumab in adults with moderate-to-severe atopic dermatitis inadequately controlled by topical treatments: a randomised, placebo-controlled, dose-ranging p... von Thaçi, Diamant, Prof, Simpson, Eric L, MD, Beck, Lisa A, Prof, Bieber, Thomas, Prof, Blauvelt, Andrew, MD, Papp, Kim, MD, Soong, Weily, MD, Worm, Margitta, Univ-Prof, Szepietowski, Jacek C, Prof, Sofen, Howard, MD, Kawashima, Makoto, Prof, Wu, Richard, PhD, Weinstein, Steven P, MD, Graham, Neil M H, MD, Pirozzi, Gianluca, MD, Teper, Ariel, MD, Sutherland, E Rand, MD, Mastey, Vera, MS, Stahl, Neil, PhD, Yancopoulos, George D, MD, Ardeleanu, Marius, MD

Volltext

Efficacy and safety of dupilumab in perennial allergic rhinitis and comorbid asthma von Weinstein, Steven F., Katial, Rohit, Jayawardena, Shyamalie, Pirozzi, Gianluca, Staudinger, Heribert, Eckert, Laurent, Joish, Vijay N., Amin, Nikhil, Maroni, Jaman, Rowe, Paul, Graham, Neil M.H., Teper, Ariel

Volltext

Dupilumab improves the molecular signature in skin of patients with moderate-to-severe atopic dermatitis von Hamilton, Jennifer D., PhD, Suárez-Fariñas, Mayte, PhD, Dhingra, Nikhil, BS, Cardinale, Irma, MSc, Li, Xuan, PhD, Kostic, Ana, PhD, Ming, Jeffrey E., MD, PhD, Radin, Allen R., MD, Krueger, James G., MD, Graham, Neil, MD, Yancopoulos, George D., MD, PhD, Pirozzi, Gianluca, MD, PhD, Guttman-Yassky, Emma, MD, PhD

Volltext

Infections in Dupilumab Clinical Trials in Atopic Dermatitis: A Comprehensive Pooled Analysis von Eichenfield, Lawrence F., Bieber, Thomas, Beck, Lisa A., Simpson, Eric L., Thaçi, Diamant, de Bruin-Weller, Marjolein, Deleuran, Mette, Silverberg, Jonathan I., Ferrandiz, Carlos, Fölster-Holst, Regina, Chen, Zhen, Graham, Neil M. H., Pirozzi, Gianluca, Akinlade, Bolanle, Yancopoulos, George D., Ardeleanu, Marius

Volltext

Dupilumab therapy provides clinically meaningful improvement in patient-reported outcomes (PROs): A phase IIb, randomized, placebo-controlled, clinical trial in adult patients with... von Simpson, Eric L., MD, MCR, Gadkari, Abhijit, PhD, Worm, Margitta, MD, Soong, Weily, MD, Blauvelt, Andrew, MD, MBA, Eckert, Laurent, PhD, Wu, Richard, PhD, Ardeleanu, Marius, MD, Graham, Neil M.H., MD, PhD, Pirozzi, Gianluca, MD, PhD, Sutherland, E. Rand, MD, MPH, Mastey, Vera, BPharm, MS

Volltext

Dupilumab Versus Cyclosporine for the Treatment of Moderate-to-Severe Atopic Dermatitis in Adults: Indirect Comparison Using the Eczema Area and Severity Index von Ariëns, Lieneke F M, Gadkari, Abhijit, van Os-Medendorp, Harmieke, Ayyagari, Rajeev, Terasawa, Emi, Kuznik, Andreas, Chen, Zhen, Bégo-Le Bagousse, Gaëlle, Lu, Yufang, Rizova, Elena, Graham, Neil M H, Pirozzi, Gianluca, De Bruin-Weller, Marjolein, Eckert, Laurent

Volltext

Dupilumab improves lung function in patients with uncontrolled, moderate-to-severe asthma von Castro, Mario, Rabe, Klaus F, Corren, Jonathan, Pavord, Ian D, Katelaris, Constance H, Tohda, Yuji, Zhang, Bingzhi, Rice, Megan S, Maroni, Jaman, Rowe, Paul, Pirozzi, Gianluca, Amin, Nikhil, Ruddy, Marcella, Akinlade, Bolanle, Graham, Neil M H, Teper, Ariel

Volltext

The Importance of Controlling Terminal Complement Activity and Intravascular Hemolysis in Paroxysmal Nocturnal Hemoglobinuria (PNH) von Hill, Anita, Hotermans, Christophe, Pirozzi, Gianluca

Volltext

Long-Term Safety and Efficacy of Open-Label Dupilumab in Patients with Moderate-to-Severe Atopic Dermatitis von Deleuran, Mette, Prof, Thaçi, Diamant, Prof, Beck, Lisa A., Prof, Forman, Seth, Dr, Soong, Weily, Dr, Hussain, Iftikhar, Dr, Bissonnette, Robert, Dr, Bouaziz, Jean-David, Dr, Gelfand, Joel, Prof, Sher, Lawrence, Dr, Chen, Zhen, Dr, Akinlade, Bolanle, Dr, Gadkari, Abhijit, Dr, Eckert, Laurent, Dr, Graham, Neil M.H., Dr, Pirozzi, Gianluca, Dr, Ardeleanu, Marius, Dr

Volltext

Dupilumab Suppresses Fractional Exhaled Nitric Oxide (FeNO) and Biomarkers of Type 2 Inflammation in Adult Patients with Persistent Uncontrolled Asthma Despite Use of Medium-to-Hig... von Swanson, Brian N., PhD, Teper, Ariel, MD, Hamilton, Jennifer D., PhD, Zhang, Bingzhi, PhD, Staudinger, Heribert, MD, Tian, Nian, Wang, Ying, PhD, Ming, Jeffrey E., MD, PhD, Graham, Neil M.H., MD, Pirozzi, Gianluca, MD, PhD

Volltext

Safety and Efficacy Of Dupilumab Versus Placebo For Moderate-To-Severe Atopic Dermatitis In Patients Using Topical Corticosteroids (TCS): Greater Efficacy Observed With Concomitant... von Thaci, Diamant, Dr, Worm, Margitta, Dr, Ren, Haobo, Dr, Weinstein, Steven, Dr, Graham, Neil, Dr, Pirozzi, Gianluca, Dr, Brooks, Warren, PhD, Ardeleanu, Marius, Dr

Volltext

The CD85j+ NK cell subset potently controls HIV-1 replication in autologous dendritic cells von Scott-Algara, Daniel, Arnold, Vincent, Didier, Céline, Kattan, Tarek, Pirozzi, Gianluca, Barré-Sinoussi, Françoise, Pancino, Gianfranco

Volltext