The p53 tumor suppressor protein is a critical regulator of hematopoietic stem cell behavior von Liu, Yan, Elf, Shannon E., Asai, Takashi, Miyata, Yasuhiko, Liu, Yuhui, Sashida, Goro, Huang, Gang, Di Giandomenico, Silvana, Koff, Andrew, Nimer, Stephen D.

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p53 Regulates Hematopoietic Stem Cell Quiescence von YAN LIU, ELF, Shannon E, ANTIPIN, Jack, REVA, Boris, KOFF, Andrew, NIMER, Stephen D, MIYATA, Yasuhiko, SASHIDA, Goro, YUHUI LIU, GANG HUANG, DI GIANDOMENICO, Silvana, LEE, Jennifer M, DEBLASIO, Anthony, MENENDEZ, Silvia

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Resistance to platinum-based chemotherapy is associated with epithelial to mesenchymal transition in epithelial ovarian cancer von Marchini, Sergio, Fruscio, Robert, Clivio, Luca, Beltrame, Luca, Porcu, Luca, Nerini, Ilaria Fuso, Cavalieri, Duccio, Chiorino, Giovanna, Cattoretti, Giorgio, Mangioni, Costantino, Milani, Rodolfo, Torri, Valter, Romualdi, Chiara, Zambelli, Alberto, Romano, Michela, Signorelli, Mauro, Giandomenico, Silvana di, D’Incalci, Maurizio

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Hepcidin Is Essential for Alveolar Macrophage Function and Is Disrupted by Smoke in a Murine Chronic Obstructive Pulmonary Disease Model von Perez, Elizabeth, Baker, Jonathan R, Di Giandomenico, Silvana, Kermani, Pouneh, Parker, Jacqueline, Kim, Kihwan, Yang, Jianjun, Barnes, Peter J, Vaulont, Sophie, Scandura, Joseph M, Donnelly, Louise E, Stout-Delgado, Heather, Cloonan, Suzanne M

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Combination of PI3K/mTOR Inhibitors: Antitumor Activity and Molecular Correlates von MAZZOLETTI, Marco, BORTOLIN, Francesca, BRUNELLI, Laura, PASTORELLI, Roberta, DI GIANDOMENICO, Silvana, ERBA, Eugenio, UBEZIO, Paolo, BROGGINI, Massimo

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Trabectedin efficacy in Ewing sarcoma is greatly increased by combination with anti-IGF signaling agents von Amaral, Ana Teresa, Garofalo, Cecilia, Frapolli, Roberta, Manara, Maria Cristina, Mancarella, Caterina, Uboldi, Sarah, Di Giandomenico, Silvana, Ordóñez, Jose Luis, Sevillano, Victoria, Malaguarnera, Roberta, Picci, Piero, Hassan, A Bass, De Alava, Enrique, D'Incalci, Maurizio, Scotlandi, Katia

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Necdin, a p53 target gene, regulates the quiescence and response to genotoxic stress of hematopoietic stem/progenitor cells von Asai, Takashi, Liu, Yan, Di Giandomenico, Silvana, Bae, Narae, Ndiaye-Lobry, Delphine, Deblasio, Anthony, Menendez, Silvia, Antipin, Yevgeniy, Reva, Boris, Wevrick, Rachel, Nimer, Stephen D.

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The Mef/Elf4 Transcription Factor Fine Tunes the DNA Damage Response von SASHIDA, Goro, BAE, Narae, NIMER, Stephen D, DI GIANDOMENICO, Silvana, ASAI, Takashi, GURVICH, Nadia, BAZZOLI, Elena, YAN LIU, GANG HUANG, XINYANG ZHAO, MENENDEZ, Silvia

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JAK2 V617F Impairs T Cell Differentiation in Polycythemia Vera von Choi, Daniel C, Abu-Zeinah, Ghaith, Di Giandomenico, Silvana, Erdos, Katie, Scandura, Joseph

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JAK2V617F Impairs T Cell Differentiation in Polycythemia Vera von Choi, Daniel C, Abu-Zeinah, Ghaith, Di Giandomenico, Silvana, Erdos, Katie, Scandura, Joseph

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Hematopoietic Stem and Progenitor Cell Fitness As a Novel Prognostic and Monitoring Biomarker for JAK2 V617F Myeloproliferative Neoplasms (MPNs) von Abu-Zeinah, Ghaith, Di Giandomenico, Silvana, Cruz, Tatiana, Choi, Daniel, Taylor, Elwood, Ritchie, Ellen, Silver, Richard T., Scandura, Joseph

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Low-Dose Epo after Tgfβ Blockade Triggers Robust Erythropoiesis and Increased RBC Production von Di Giandomenico, Silvana, Abu Zeinah, Ghaith, Kermani, Pouneh, Yabut, Mia, Stephens, Thomas, Messali, Nassima, Scandura, Joseph

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Antiangiogenic activity of trabectedin in myxoid liposarcoma: Involvement of host TIMP‐1 and TIMP‐2 and tumor thrombospondin‐1 von Dossi, Romina, Frapolli, Roberta, Di Giandomenico, Silvana, Paracchini, Lara, Bozzi, Fabio, Brich, Silvia, Castiglioni, Vittoria, Borsotti, Patrizia, Belotti, Dorina, Uboldi, Sarah, Sanfilippo, Roberta, Erba, Eugenio, Giavazzi, Raffaella, Marchini, Sergio, Pilotti, Silvana, D'Incalci, Maurizio, Taraboletti, Giulia

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Diffuse Large B Cell Pdtx in Humanized Mice Are Valuable Models to Study Host-Lymphoma Interactions and Immune-Modulating Agents von Zanetti, Giorgia, Astone, Giuseppina, Cappelli, Luca, Chiu, William, Cacciapuoti, Maria Teresa, Kayembe, Clarisse, Fiore, Danilo, Tam, Wayne, Scandura, Joseph, Di Giandomenico, Silvana, Galluzzi, Lorenzo, Roth, Lisa Giulino, Inghirami, Giorgio

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Megakaryocytic TGFβ1 Partitions Hematopoiesis into Amplifying Stem and Progenitor Cells and Maturing Effector Cells von Di Giandomenico, Silvana, Kermani, Pouneh, Molle, Nicole, Yabut, Mia, Brenet, Fabienne, Rafii, Shahin, Scandura, Joseph

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Hepcidin is essential for alveolar macrophage function and is disrupted by smoke in a murine COPD model von Perez, Elizabeth, Baker, Jonathan R., Di Giandomenico, Silvana, Kermani, Pouneh, Parker, Jacqueline, Kim, Kihwan, Yang, Jianjun, Barnes, Peter J., Vaulont, Sophie, Scandura, Joseph M., Donnelly, Louise E., Stout-Delgado, Heather, Cloonan, Suzanne M.

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Megakaryocyte TGFβ1 partitions erythropoiesis into immature progenitor/stem cells and maturing precursors von Di Giandomenico, Silvana, Kermani, Pouneh, Mollé, Nicole, Yabut, Maria Mia, Abu-Zeinah, Ghaith, Stephens, Thomas, Messali, Nassima, Schreiner, Ryan, Brenet, Fabienne, Rafii, Shahin, Scandura, Joseph M.

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Controlling Hematopoietic Stem Cell Quiescence By Ablating the TGFβ-Responsive, Hematopoietic-Hpecific Enhancer of CDKN1C (p57) von Yabut, Mia, Brenet, Fabienne, Messali, Nassima, Molle, Nicole, Kermani, Pouneh, Di Giandomenico, Silvana, Brown, Matthew, Scandura, Joseph

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Myeloproliferative Neoplasm (MPN) Driver Mutations Are Enriched during Hematopoietic Stem Cell Differentiation in Patterns That Correlate with Clinical Phenotype and Treatment Resp... von Abu-Zeinah, Ghaith, Di Giandomenico, Silvana, Sosner, Claudia, Savage, Niamh, Krichevsky, Spencer, Ritchie, Ellen K., Kermani, Pouneh, Silver, Richard T., Scandura, Joseph

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Abstract 4646: A novel truncated variant of the hematopoietic Hβ-1 tubulin isotype with implications for stem cell biology von Bai, Yang, Basciano, Paul, Li, Xi, Matakas, Jason, Giandomenico, Silvana Di, Sen, Siddhartha, Evans, Todd, Scandura, Joseph, Guzman, Monica, Giannakakou, Paraskevi

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