Ferroportin deficiency in erythroid cells causes serum iron deficiency and promotes hemolysis due to oxidative stress von Zhang, De-Liang, Ghosh, Manik C., Ollivierre, Hayden, Li, Yan, Rouault, Tracey A.

Volltext

Iron Chaperone Poly rC Binding Protein 1 Protects Mouse Liver From Lipid Peroxidation and Steatosis von Protchenko, Olga, Baratz, Ethan, Jadhav, Shyamalagauri, Li, Fengmin, Shakoury‐Elizeh, Minoo, Gavrilova, Oksana, Ghosh, Manik C., Cox, James E., Maschek, J. Alan, Tyurin, Vladimir A., Tyurina, Yulia Y., Bayir, Hülya, Aron, Allegra T., Chang, Christopher J., Kagan, Valerian E., Philpott, Caroline C.

Volltext

Dysfunction of the heme recycling system in heme oxygenase 1–deficient mice: effects on macrophage viability and tissue iron distribution von Kovtunovych, Gennadiy, Eckhaus, Michael A., Ghosh, Manik C., Ollivierre-Wilson, Hayden, Rouault, Tracey A.

Volltext

Erythrocytic ferroportin reduces intracellular iron accumulation, hemolysis, and malaria risk von Zhang, De-Liang, Wu, Jian, Shah, Binal N, Greutélaers, Katja C, Ghosh, Manik C, Ollivierre, Hayden, Su, Xin-Zhuan, Thuma, Philip E, Bedu-Addo, George, Mockenhaupt, Frank P, Gordeuk, Victor R, Rouault, Tracey A

Volltext

The physiological functions of iron regulatory proteins in iron homeostasis - an update von Zhang, De-Liang, Ghosh, Manik C, Rouault, Tracey A

Volltext

Iron misregulation and neurodegenerative disease in mouse models that lack iron regulatory proteins von Ghosh, Manik C, Zhang, De-Liang, Rouault, Tracey A

Volltext

Iron chaperones PCBP1 and PCBP2 mediate the metallation of the dinuclear iron enzyme deoxyhypusine hydroxylase von Frey, Avery G, Nandal, Anjali, Park, Jong Hwan, Smith, Pamela M, Yabe, Toshiki, Ryu, Moon-Suhn, Ghosh, Manik C, Lee, Jaekwon, Rouault, Tracey A, Park, Myung Hee, Philpott, Caroline C

Volltext

Deletion of Iron Regulatory Protein 1 Causes Polycythemia and Pulmonary Hypertension in Mice through Translational Derepression of HIF2α von Ghosh, Manik C., Zhang, De-Liang, Jeong, Suh Young, Kovtunovych, Gennadiy, Ollivierre-Wilson, Hayden, Noguchi, Audrey, Tu, Tiffany, Senecal, Thomas, Robinson, Gabrielle, Crooks, Daniel R., Tong, Wing-Hang, Ramaswamy, Kavitha, Singh, Anamika, Graham, Brian B., Tuder, Rubin M., Yu, Zu-Xi, Eckhaus, Michael, Lee, Jaekwon, Springer, Danielle A., Rouault, Tracey A.

Volltext

Autotaxin and LPA1 and LPA5 receptors exert disparate functions in tumor cells versus the host tissue microenvironment in melanoma invasion and metastasis von Lee, Sue-Chin, Fujiwara, Yuko, Liu, Jianxiong, Yue, Junming, Shimizu, Yoshibumi, Norman, Derek D, Wang, Yaohong, Tsukahara, Ryoko, Szabo, Erzsebet, Patil, Renukadevi, Banerjee, Souvik, Miller, Duane D, Balazs, Louisa, Ghosh, Manik C, Waters, Christopher M, Oravecz, Tamas, Tigyi, Gabor J

Volltext

Wild-type macrophages reverse disease in heme oxygenase 1-deficient mice von Kovtunovych, Gennadiy, Ghosh, Manik C., Ollivierre, Wade, Weitzel, R. Patrick, Eckhaus, Michael A., Tisdale, John F., Yachie, Akihiro, Rouault, Tracey A.

Volltext

Correction: Mutations in LRRK2 linked to Parkinson disease sequester Rab8a to damaged lysosomes and regulate transferrin-mediated iron uptake in microglia von Mamais, Adamantios, Kluss, Jillian H, Bonet-Ponce, Luis, Landeck, Natalie, Langston, Rebekah G, Smith, Nathan, Beilina, Alexandra, Kaganovich, Alice, Ghosh, Manik C, Pellegrini, Laura, Kumaran, Ravindran, Papazoglou, Ioannis, Heaton, George R, Harvey, Kirsten, Bandopadhyay, Rina, Maio, Nunziata, Kim, Changyoun, LaVoie, Matthew J, Gershlick, David C, Cookson, Mark R

Volltext

CXCR4 regulates migration of lung alveolar epithelial cells through activation of Rac1 and matrix metalloproteinase-2 von Ghosh, Manik C, Makena, Patrudu S, Gorantla, Vijay, Sinclair, Scott E, Waters, Christopher M

Volltext

Posttranslational stability of the heme biosynthetic enzyme ferrochelatase is dependent on iron availability and intact iron-sulfur cluster assembly machinery von Crooks, Daniel R., Ghosh, Manik C., Haller, Ronald G., Tong, Wing-Hang, Rouault, Tracey A.

Volltext

Insulin-like growth factor-I stimulates differentiation of ATII cells to ATI-like cells through activation of Wnt5a von Ghosh, Manik C, Gorantla, Vijay, Makena, Patrudu S, Luellen, Charlean, Sinclair, Scott E, Schwingshackl, Andreas, Waters, Christopher M

Volltext

Iron insufficiency compromises motor neurons and their mitochondrial function in Irp2-null mice von Jeong, Suh Young, Crooks, Daniel R, Wilson-Ollivierre, Hayden, Ghosh, Manik C, Sougrat, Rachid, Lee, Jaekwon, Cooperman, Sharon, Mitchell, James B, Beaumont, Carole, Rouault, Tracey A

Volltext

Mammalian Tissue Oxygen Levels Modulate Iron-Regulatory Protein Activities in Vivo von Meyron-Holtz, Esther G, Ghosh, Manik C, Rouault, Tracey A

Volltext

Membrane phospholipid augments cytochrome P4501a enzymatic activity by modulating structural conformation during detoxification of xenobiotics von Ghosh, Manik C, Ray, Arun K

Volltext

Genetic ablations of iron regulatory proteins 1 and 2 reveal why iron regulatory protein 2 dominates iron homeostasis von Meyron-Holtz, Esther G, Ghosh, Manik C, Iwai, Kazuhiro, LaVaute, Timothy, Brazzolotto, Xavier, Berger, Urs V, Land, William, Ollivierre-Wilson, Hayden, Grinberg, Alex, Love, Paul, Rouault, Tracey A

Volltext

Tempol-mediated activation of latent iron regulatory protein activity prevents symptoms of neurodegenerative disease in IRP2 knockout mice von Ghosh, Manik C, Tong, Wing-Hang, Zhang, Deliang, Ollivierre-Wilson, Hayden, Singh, Anamika, Krishna, Murali C, Mitchell, James B, Rouault, Tracey A

Volltext

Absence of iron-responsive element-binding protein 2 causes a novel neurodegenerative syndrome von Costain, Gregory, Ghosh, Manik C, Maio, Nunziata, Carnevale, Amanda, Si, Yue C, Rouault, Tracey A, Yoon, Grace

Volltext