Oxicams Bind in a Novel Mode to the Cyclooxygenase Active Site via a Two-water-mediated H-bonding Network von Xu, Shu, Hermanson, Daniel J., Banerjee, Surajit, Ghebreselasie, Kebreab, Clayton, Gina M., Garavito, R. Michael, Marnett, Lawrence J.

Volltext

Design, Synthesis, and Structure–Activity Relationship Studies of Fluorescent Inhibitors of Cycloxygenase‑2 as Targeted Optical Imaging Agents von Uddin, Md. Jashim, Crews, Brenda C, Ghebreselasie, Kebreab, Marnett, Lawrence J

Volltext

Cyclooxygenase-1-Selective Inhibitors Based on the (E)-2′-Des-methyl-sulindac Sulfide Scaffold von Liedtke, Andy J, Crews, Brenda C, Daniel, Cristina M, Blobaum, Anna L, Kingsley, Philip J, Ghebreselasie, Kebreab, Marnett, Lawrence J

Volltext

nido-Dicarbaborate Induces Potent and Selective Inhibition of Cyclooxygenase-2 von Neumann, Wilma, Xu, Shu, Sárosi, Menyhárt B., Scholz, Matthias S., Crews, Brenda C., Ghebreselasie, Kebreab, Banerjee, Surajit, Marnett, Lawrence J., Hey-Hawkins, Evamarie

Volltext

Trifluoromethyl Fluorocoxib A Detects Cyclooxygenase‑2 Expression in Inflammatory Tissues and Human Tumor Xenografts von Uddin, Md. Jashim, Crews, Brenda C, Huda, Imran, Ghebreselasie, Kebreab, Daniel, Cristina K, Marnett, Lawrence J

Volltext

Discovery of Furanone-Based Radiopharmaceuticals for Diagnostic Targeting of COX‑1 in Ovarian Cancer von Uddin, Md. Jashim, Wilson, Andrew J, Crews, Brenda C, Malerba, Paola, Uddin, Md. Imam, Kingsley, Philip J, Ghebreselasie, Kebreab, Daniel, Cristina K, Nickels, Michael L, Tantawy, Mohammed N, Jashim, Elma, Manning, H. Charles, Khabele, Dineo, Marnett, Lawrence J

Volltext

Chemical stability of 2-arachidonylglycerol under biological conditions von Rouzer, Carol A, Ghebreselasie, Kebreab, Marnett, Lawrence J

Volltext

Fluorescent indomethacin-dansyl conjugates utilize the membrane-binding domain of cyclooxygenase-2 to block the opening to the active site von Xu, Shu, Uddin, Md. Jashim, Banerjee, Surajit, Duggan, Kelsey, Musee, Joel, Kiefer, James R., Ghebreselasie, Kebreab, Rouzer, Carol A., Marnett, Lawrence J.

Volltext

Dual cyclooxygenase–fatty acid amide hydrolase inhibitor exploits novel binding interactions in the cyclooxygenase active site von Goodman, Michael C., Xu, Shu, Rouzer, Carol A., Banerjee, Surajit, Ghebreselasie, Kebreab, Migliore, Marco, Piomelli, Daniele, Marnett, Lawrence J.

Volltext

Synthesis and evaluation of [123I]-indomethacin derivatives as COX-2 targeted imaging agents von Uddin, Md. Jashim, Crews, Brenda C., Blobaum, Anna L., Kingsley, Philip J., Ghebreselasie, Kebreab, Saleh, Sam S., Clanton, Jeffrey A., Baldwin, Ronald M., Marnett, Lawrence J.

Volltext

Conjugation of Cisplatin Analogues and Cyclooxygenase Inhibitors to Overcome Cisplatin Resistance von Neumann, Wilma, Crews, Brenda C., Sárosi, Menyhárt B., Daniel, Cristina M., Ghebreselasie, Kebreab, Scholz, Matthias S., Marnett, Lawrence J., Hey-Hawkins, Evamarie

Volltext

Dual cyclooxygenase–fatty acid amide hydrolase inhibitor exploits novel binding interactions in the cyclooxygenase active site von Goodman, Michael C., Xu, Shu, Rouzer, Carol A., Banerjee, Surajit, Ghebreselasie, Kebreab, Migliore, Marco, Piomelli, Daniele, Marnett, Lawrence J.

Volltext

Harmaline Analogs as Substrate-Selective Cyclooxygenase‑2 Inhibitors von Uddin, Md. Jashim, Xu, Shu, Crews, Brenda C, Aleem, Ansari M, Ghebreselasie, Kebreab, Banerjee, Surajit, Marnett, Lawrence J

Volltext

Activatable COX‐2 Probes in Optical Imaging of Cancer von Uddin, Md. Jashim, Crews, Brenda C, Ghebreselasie, Kebreab, Daniel, Cristina K, Marnett, Lawrence J.

Volltext

The Structural Basis of Cyclooxygenase‐2 Inhibition by Fenamates von Xu, Shu, Banerjee, Surajit, Kudalkar, Shalley N, Perry, Evan T, Ghebreselasie, Kebreab, Marnett, Lawrence J

Volltext

Action at a distance: mutations of peripheral residues transform rapid reversible inhibitors to slow, tight binders of cyclooxygenase-2 von Blobaum, Anna L, Xu, Shu, Rowlinson, Scott W, Duggan, Kelsey C, Banerjee, Surajit, Kudalkar, Shalley N, Birmingham, William R, Ghebreselasie, Kebreab, Marnett, Lawrence J

Volltext

Targeted Detection of Cyclooxygenase‑1 in Ovarian Cancer von Malerba, Paola, Crews, Brenda C, Ghebreselasie, Kebreab, Daniel, Cristina K, Jashim, Elma, Aleem, Ansari M, Salam, Redoan A, Marnett, Lawrence J, Uddin, Md. Jashim

Volltext

Antitumor Activity of Cytotoxic Cyclooxygenase‑2 Inhibitors von Uddin, Md. Jashim, Crews, Brenda C, Xu, Shu, Ghebreselasie, Kebreab, Daniel, Cristina K, Kingsley, Philip J, Banerjee, Surajit, Marnett, Lawrence J

Volltext

Fluorinated COX-2 inhibitors as agents in PET imaging of inflammation and cancer von Uddin, Md Jashim, Crews, Brenda C, Ghebreselasie, Kebreab, Huda, Imran, Kingsley, Philip J, Ansari, Mohammad Sib, Tantawy, Mohammed N, Reese, Jeffery, Marnett, Lawrence J

Volltext

PET radiotracer [18F]-P6 selectively targeting COX-1 as a novel biomarker in ovarian cancer: Preliminary investigation von Perrone, Maria Grazia, Malerba, Paola, Uddin, Md. Jashim, Vitale, Paola, Panella, Andrea, Crews, Brenda C., Daniel, Cristina K., Ghebreselasie, Kebreab, Nickels, Mike, Tantawy, Mohammed N., Manning, H. Charles, Marnett, Lawrence J., Scilimati, Antonio

Volltext