Cellular mechanisms of tissue fibrosis. 3. Novel mechanisms of kidney fibrosis von Campanholle, Gabriela, Ligresti, Giovanni, Gharib, Sina A, Duffield, Jeremy S

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Association Between Preserved Ratio Impaired Spirometry and Clinical Outcomes in US Adults von Wan, Emily S, Balte, Pallavi, Schwartz, Joseph E, Bhatt, Surya P, Cassano, Patricia A, Couper, David, Daviglus, Martha L, Dransfield, Mark T, Gharib, Sina A, Jacobs, David R, Kalhan, Ravi, London, Stephanie J, Navas-Acien, Ana, O’Connor, George T, Sanders, Jason L, Smith, Benjamin M, White, Wendy, Yende, Sachin, Oelsner, Elizabeth C

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MMP28 promotes macrophage polarization toward M2 cells and augments pulmonary fibrosis von Gharib, Sina A., Johnston, Laura K., Huizar, Isham, Birkland, Timothy P., Hanson, Josiah, Wang, Ying, Parks, William C., Manicone, Anne M.

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Leveraging pleiotropy to discover and interpret GWAS results for sleep-associated traits von Chun, Sung, Akle, Sebastian, Teodosiadis, Athanasios, Cade, Brian E, Wang, Heming, Sofer, Tamar, Evans, Daniel S, Stone, Katie L, Gharib, Sina A, Mukherjee, Sutapa, Palmer, Lyle J, Hillman, David, Rotter, Jerome I, Hanis, Craig L, Stamatoyannopoulos, John A, Redline, Susan, Cotsapas, Chris, Sunyaev, Shamil R

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Stromelysin-2 (MMP10) Moderates Inflammation by Controlling Macrophage Activation von McMahan, Ryan S, Birkland, Timothy P, Smigiel, Kate S, Vandivort, Tyler C, Rohani, Maryam G, Manicone, Anne M, McGuire, John K, Gharib, Sina A, Parks, William C

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Pericyte TIMP3 and ADAMTS1 Modulate Vascular Stability after Kidney Injury von SCHRIMPF, Claudia, CUIYAN XIN, CAMPANHOLLE, Gabriella, GILL, Sean E, STALLCUP, William, LIN, Shuei-Liong, DAVIS, George E, GHARIB, Sina A, HUMPHREYS, Benjamin D, DUFFIELD, Jeremy S

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Concomitant western diet and chronic-binge alcohol dysregulate hepatic metabolism von Buyco, Delfin Gerard, Dempsey, Joseph L, Scorletti, Eleonora, Jeon, Sookyoung, Lin, Chelsea, Harkin, Julia, Bayen, Susovon, Furth, Emma E, Martin, Jasmin, Delima, Monique, Hooks, Royce, Sostre-Colón, Jaimarie, Gharib, Sina A, Titchenell, Paul M, Carr, Rotonya M

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Cystic fibrosis-related diabetes is associated with reduced islet protein expression of GLP-1 receptor and perturbation of cell-specific transcriptional programs von Gharib, Sina A., Vemireddy, Rachna, Castillo, Joseph J., Fountaine, Brendy S., Bammler, Theo K., MacDonald, James W., Hull-Meichle, Rebecca L., Zraika, Sakeneh

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Shotgun proteomics implicates protease inhibition and complement activation in the antiinflammatory properties of HDL von Vaisar, Tomas, Pennathur, Subramaniam, Green, Pattie S, Gharib, Sina A, Hoofnagle, Andrew N, Cheung, Marian C, Byun, Jaeman, Vuletic, Simona, Kassim, Sean, Singh, Pragya, Chea, Helen, Knopp, Robert H, Brunzell, John, Geary, Randolph, Chait, Alan, Zhao, Xue-Qiao, Elkon, Keith, Marcovina, Santica, Ridker, Paul, Oram, John F, Heinecke, Jay W

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HHV-6B detection and host gene expression implicate HHV-6B as pulmonary pathogen after hematopoietic cell transplant von Hill, Joshua A., Lee, Yeon Joo, Vande Vusse, Lisa K., Xie, Hu, Chung, E. Lisa, Waghmare, Alpana, Cheng, Guang-Shing, Zhu, Haiying, Huang, Meei-Li, Hill, Geoffrey R., Jerome, Keith R., Leisenring, Wendy M., Zerr, Danielle M., Gharib, Sina A., Dadwal, Sanjeet, Boeckh, Michael

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Distinct patterns of transcriptional and epigenetic alterations characterize acute and chronic kidney injury von Sharifian, Roya, Okamura, Daryl M., Denisenko, Oleg, Zager, Richard A., Johnson, Ali, Gharib, Sina A., Bomsztyk, Karol

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Type I IFN induces long-chain acyl-CoA synthetase 1 to generate a phosphatidic acid reservoir for lipotoxic saturated fatty acids von Barnhart, Shelley, Shimizu-Albergine, Masami, Kedar, Eyal, Kothari, Vishal, Shao, Baohai, Krueger, Melissa, Hsu, Cheng-Chieh, Tang, Jingjing, Kanter, Jenny E., Kramer, Farah, Djukovic, Danijel, Pascua, Vadim, Loo, Yueh-Ming, Colonna, Lucrezia, Van den Bogaerde, Sadie J., An, Jie, Gale, Michael, Reue, Karen, Fisher, Edward A., Gharib, Sina A., Elkon, Keith B., Bornfeldt, Karin E.

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CYP2J2 Modulates Diverse Transcriptional Programs in Adult Human Cardiomyocytes von Evangelista, Eric A., Aliwarga, Theresa, Sotoodehnia, Nona, Jensen, Paul N., McKnight, Barbara, Lemaitre, Rozenn N., Totah, Rheem A., Gharib, Sina A.

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Integrative miRNA-mRNA profiling of adipose tissue unravels transcriptional circuits induced by sleep fragmentation von Gharib, Sina A, Khalyfa, Abdelnaby, Abdelkarim, Amal, Bhushan, Bharat, Gozal, David

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TLR-2/TLR-4 TREM-1 signaling pathway is dispensable in inflammatory myeloid cells during sterile kidney injury von Campanholle, Gabriela, Mittelsteadt, Kristen, Nakagawa, Shunsaku, Kobayashi, Akio, Lin, Shuei-Liong, Gharib, Sina A, Heinecke, Jay W, Hamerman, Jessica A, Altemeier, William A, Duffield, Jeremy S

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Development and validation of a metabolite index for obstructive sleep apnea across race/ethnicities von Zhang, Ying, Ngo, Debby, Yu, Bing, Shah, Neomi A., Chen, Han, Ramos, Alberto R., Zee, Phyllis C., Tracy, Russell, Durda, Peter, Kaplan, Robert, Daviglus, Martha L., Rich, Stephen S., Rotter, Jerome I., Cai, Jianwen, Clish, Clary, Gerszten, Robert, Kristal, Bruce S., Gharib, Sina A., Redline, Susan, Sofer, Tamar

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Lipidomics reveals dramatic lipid compositional changes in the maturing postnatal lung von Dautel, Sydney E., Kyle, Jennifer E., Clair, Geremy, Sontag, Ryan L., Weitz, Karl K., Shukla, Anil K., Nguyen, Son N., Kim, Young-Mo, Zink, Erika M., Luders, Teresa, Frevert, Charles W., Gharib, Sina A., Laskin, Julia, Carson, James P., Metz, Thomas O., Corley, Richard A., Ansong, Charles

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Induced sputum proteome in healthy subjects and asthmatic patients von Gharib, Sina A., MD, Nguyen, Elizabeth V., BS, Lai, Ying, PhD, Plampin, Jessica D., BS, Goodlett, David R., PhD, Hallstrand, Teal S., MD, MPH

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Matrix Metalloproteinase-28 Is a Key Contributor to Emphysema Pathogenesis von Manicone, Anne M, Gharib, Sina A, Gong, Ke-Qin, Eddy, William E, Long, Matthew E, Frevert, Charles W, Altemeier, William A, Parks, William C, Houghton, A. McGarry

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Matrix Metalloproteinase-12 Is Required for Granuloma Progression von Mohan, Arjun, Neequaye, Nicole, Malur, Anagha, Soliman, Eman, McPeek, Matthew, Leffler, Nancy, Ogburn, David, Tokarz, Debra A, Knudson, Warren, Gharib, Sina A, Schnapp, Lynn M, Barna, Barbara P, Thomassen, Mary Jane

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