Rational design and diversity-oriented synthesis of peptoid-based selective HDAC6 inhibitors von Diedrich, D, Hamacher, A, Gertzen, C. G. W, Alves Avelar, L. A, Reiss, G. J, Kurz, T, Gohlke, H, Kassack, M. U, Hansen, F. K

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Phosphorylated tyrosine 93 of hepatitis C virus nonstructural protein 5A is essential for interaction with host c-Src and efficient viral replication von Klinker, Stefan, Stindt, Sabine, Gremer, Lothar, Bode, Johannes G., Gertzen, Christoph G.W., Gohlke, Holger, Weiergräber, Oliver H., Hoffmann, Silke, Willbold, Dieter

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Aplospojaveedins A-C, unusual sulfur-containing alkaloids produced by the endophytic fungus Aplosporella javeedii using OSMAC strategy von Gao, Ying, Frank, Marian, Teusch, Nicole, Woschko, Dennis, Janiak, Christoph, Mándi, Attila, Kurtán, Tibor, Hartmann, Rudolf, Schiedlauske, Katja, van Geelen, Lasse, Kalscheuer, Rainer, Kaiser, Jesko, Gertzen, Christoph G W, Gohlke, Holger, Wang, Bin-Gui, Proksch, Peter, Liu, Zhen

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Time-resolved structural analysis of an RNA-cleaving DNA catalyst von Borggräfe, Jan, Victor, Julian, Rosenbach, Hannah, Viegas, Aldino, Gertzen, Christoph G. W., Wuebben, Christine, Kovacs, Helena, Gopalswamy, Mohanraj, Riesner, Detlev, Steger, Gerhard, Schiemann, Olav, Gohlke, Holger, Span, Ingrid, Etzkorn, Manuel

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The architecture of the 10‐23 DNAzyme and its implications for DNA‐mediated catalysis von Borggräfe, Jan, Gertzen, Christoph G. W., Viegas, Aldino, Gohlke, Holger, Etzkorn, Manuel

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Loop 1 of APOBEC3C Regulates its Antiviral Activity against HIV-1 von Jaguva Vasudevan, Ananda Ayyappan, Balakrishnan, Kannan, Gertzen, Christoph G.W., Borvető, Fanni, Zhang, Zeli, Sangwiman, Anucha, Held, Ulrike, Küstermann, Caroline, Banerjee, Sharmistha, Schumann, Gerald G., Häussinger, Dieter, Bravo, Ignacio G., Gohlke, Holger, Münk, Carsten

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JAK2 p.G571S in B-cell precursor acute lymphoblastic leukemia: a synergizing germline susceptibility von Lin, Minhui, Nebral, Karin, Gertzen, Christoph G. W., Ganmore, Ithamar, Haas, Oskar A., Bhatia, Sanil, Fischer, Ute, Kuhlen, Michaela, Gohlke, Holger, Izraeli, Shai, Trka, Jan, Hu, Jianda, Borkhardt, Arndt, Hauer, Julia, Auer, Franziska

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Structure and function of redox-sensitive superfolder green fluorescent protein variant von Heimsch, Kim, Gertzen, Christoph-G W, Schuh, Katharina, Nietzel, Thomas, Rahlfs, Stefan, Przyborski, Jude, Gohlke, Holger, Schwarzländer, Markus, Becker, Katja, Fritz-Wolf, Karin

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Dimerization energetics of the G‐protein coupled bile acid receptor TGR5 from all‐atom simulations von Wäschenbach, Lucas, Gertzen, Christoph G. W., Keitel, Verena, Gohlke, Holger

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A Membrane-proximal, C-terminal α-Helix Is Required for Plasma Membrane Localization and Function of the G Protein-coupled Receptor (GPCR) TGR5 von Spomer, Lina, Gertzen, Christoph G.W., Schmitz, Birte, Häussinger, Dieter, Gohlke, Holger, Keitel, Verena

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Alkoxyurea-Based Histone Deacetylase Inhibitors Increase Cisplatin Potency in Chemoresistant Cancer Cell Lines von Stenzel, Katharina, Hamacher, Alexandra, Hansen, Finn K, Gertzen, Christoph G. W, Senger, Johanna, Marquardt, Viktoria, Marek, Linda, Marek, Martin, Romier, Christophe, Remke, Marc, Jung, Manfred, Gohlke, Holger, Kassack, Matthias U, Kurz, Thomas

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Regulation of STING activity in DNA sensing by ISG15 modification von Lin, Chaohui, Kuffour, Edmund Osei, Fuchs, Nina V., Gertzen, Christoph G.W., Kaiser, Jesko, Hirschenberger, Maximilian, Tang, Xiao, Xu, Haifeng C., Michel, Oliver, Tao, Ronny, Haase, Alexandra, Martin, Ulrich, Kurz, Thomas, Drexler, Ingo, Görg, Boris, Lang, Philipp A., Luedde, Tom, Sparrer, Konstantin M.J., Gohlke, Holger, König, Renate, Münk, Carsten

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The many facets of bile acids in the physiology and pathophysiology of the human liver von Gertzen, Christoph G.W., Gohlke, Holger, Häussinger, Dieter, Herebian, Diran, Keitel, Verena, Kubitz, Ralf, Mayatepek, Ertan, Schmitt, Lutz

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Synthesis of Peptoid-Based Class I‑Selective Histone Deacetylase Inhibitors with Chemosensitizing Properties von Krieger, Viktoria, Hamacher, Alexandra, Cao, Fangyuan, Stenzel, Katharina, Gertzen, Christoph G. W, Schäker-Hübner, Linda, Kurz, Thomas, Gohlke, Holger, Dekker, Frank J, Kassack, Matthias U, Hansen, Finn K

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Design, Multicomponent Synthesis, and Anticancer Activity of a Focused Histone Deacetylase (HDAC) Inhibitor Library with Peptoid-Based Cap Groups von Krieger, Viktoria, Hamacher, Alexandra, Gertzen, Christoph G. W, Senger, Johanna, Zwinderman, Martijn R. H, Marek, Martin, Romier, Christophe, Dekker, Frank J, Kurz, Thomas, Jung, Manfred, Gohlke, Holger, Kassack, Matthias U, Hansen, Finn K

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The ISG15-Protease USP18 Is a Pleiotropic Enhancer of HIV-1 Replication von Lin, Chaohui, Kuffour, Edmund Osei, Li, Taolan, Gertzen, Christoph G W, Kaiser, Jesko, Luedde, Tom, König, Renate, Gohlke, Holger, Münk, Carsten

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DNA-binding and protein structure of nuclear factors likely acting in genetic information processing in the Paulinella chromatophore von Macorano, Luis, Binny, Taniya M, Spiegl, Tobias, Klimenko, Victoria, Singer, Anna, Oberleitner, Linda, Applegate, Violetta, Seyffert, Sarah, Stefanski, Anja, Gremer, Lothar, Gertzen, Christoph G W, Höppner, Astrid, Smits, Sander H J, Nowack, Eva C M

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Mutational mapping of the transmembrane binding site of the G-protein coupled receptor TGR5 and binding mode prediction of TGR5 agonists von Gertzen, Christoph G.W., Spomer, Lina, Smits, Sander H.J., Häussinger, Dieter, Keitel, Verena, Gohlke, Holger

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A Plurizyme with Transaminase and Hydrolase Activity Catalyzes Cascade Reactions von Roda, Sergi, Fernandez‐Lopez, Laura, Benedens, Marius, Bollinger, Alexander, Thies, Stephan, Schumacher, Julia, Coscolín, Cristina, Kazemi, Masoud, Santiago, Gerard, Gertzen, Christoph G. W., Gonzalez‐Alfonso, Jose L., Plou, Francisco J., Jaeger, Karl‐Erich, Smits, Sander H. J., Ferrer, Manuel, Guallar, Víctor

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Molecular Modeling and Simulations of DNA and RNA: DNAzyme as a Model System von Gertzen, Christoph G. W., Gohlke, Holger

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