Biased signaling of G protein-coupled receptors – From a chemokine receptor CCR7 perspective von Jørgensen, Astrid Sissel, Rosenkilde, Mette M., Hjortø, Gertrud M.

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“Glyco-sulfo barcodes” regulate chemokine receptor function von Verhallen, Lisa, Lackman, Jarkko J., Wendt, Rikke, Gustavsson, Martin, Yang, Zhang, Narimatsu, Yoshiki, Sørensen, Daniel M., Lafferty, Kato Mac, Gouwy, Mieke, Marques, Pedro E., Hjortø, Gertrud M., Rosenkilde, Mette M., Proost, Paul, Goth, Christoffer K.

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Rationally designed chemokine-based toxin targeting the viral G protein-coupled receptor US28 potently inhibits cytomegalovirus infection in vivo von Spiess, Katja, Mads G. Jeppesen, Mikkel Malmgaard-Clausen, Karen Krzywkowski, Kalpana Dulal, Tong Cheng, Gertrud M. HjortÃ, Olav Larsen, John S. Burg, Michael A. Jarvis, K. Christopher Garcia, Hua Zhu, Thomas N. Kledal, Mette M. Rosenkilde

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Chemokine binding to PSGL-1 is controlled by O-glycosylation and tyrosine sulfation von Goth, Christoffer K., Mehta, Akul Y., McQuillan, Alyssa M., Baker, Kelly J., Hanes, Melinda S., Park, Simon S., Stavenhagen, Kathrin, Hjortø, Gertrud M., Heimburg-Molinaro, Jamie, Chaikof, Elliot L., Rosenkilde, Mette M., Cummings, Richard D.

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Migration mediated by the oxysterol receptor GPR183 depends on arrestin coupling but not receptor internalization von Kjær, Viktoria M S, Daugvilaite, Viktorija, Stepniewski, Tomasz M, Madsen, Christian M, Jørgensen, Astrid S, Bhuskute, Kaustubh R, Inoue, Asuka, Ulven, Trond, Benned-Jensen, Tau, Hjorth, Siv A, Hjortø, Gertrud M, Moo, Ee Von, Selent, Jana, Rosenkilde, Mette M

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Biased Signaling of CCL21 and CCL19 Does Not Rely on N-Terminal Differences, but Markedly on the Chemokine Core Domains and Extracellular Loop 2 of CCR7 von Jørgensen, Astrid S, Larsen, Olav, Uetz-von Allmen, Edith, Lückmann, Michael, Legler, Daniel F, Frimurer, Thomas M, Veldkamp, Christopher T, Hjortø, Gertrud M, Rosenkilde, Mette M

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Arrestin‐independent constitutive endocytosis of GPR125/ADGRA3 von Spiess, Katja, Bagger, Sofie O., Torz, Lola J., Jensen, Kristian H. R., Walser, Anna L., Kvam, Jone M., Møgelmose, Ann‐Sofie K., Daugvilaite, Viktorija, Junnila, Riia K., Hjortø, Gertrud M., Rosenkilde, Mette M.

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Structural Features of an Extended C‑Terminal Tail Modulate the Function of the Chemokine CCL21 von Moussouras, Natasha A, Hjortø, Gertrud M, Peterson, Francis C, Szpakowska, Martyna, Chevigné, Andy, Rosenkilde, Mette M, Volkman, Brian F, Dwinell, Michael B

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CCL19 with CCL21‐tail displays enhanced glycosaminoglycan binding with retained chemotactic potency in dendritic cells von Jørgensen, Astrid S., Adogamhe, Pontian E., Laufer, Julia M., Legler, Daniel F., Veldkamp, Christopher T., Rosenkilde, Mette M., Hjortø, Gertrud M.

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Ligand-selective small molecule modulators of the constitutively active vGPCR US28 von Amărandi, Roxana-Maria, Lückmann, Michael, Melynis, Motiejus, Jakobsen, Mette H., Fallah, Zohreh, Spiess, Katja, Hjortø, Gertrud M., Pui, Aurel, Frimurer, Thomas M., Rosenkilde, Mette M.

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Rewiring host–microbe interactions and barrier function during gastrointestinal inflammation von Jensen, Sune K, Pærregaard, Simone I, Brandum, Emma P, Jørgensen, Astrid S, Hjortø, Gertrud M, Jensen, Benjamin A H

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Signaling via G proteins mediates tumorigenic effects of GPR87 von Niss Arfelt, Kristine, Fares, Suzan, Sparre-Ulrich, Alexander H, Hjortø, Gertrud M, Gasbjerg, Lærke S, Mølleskov-Jensen, Ann-Sofie, Benned-Jensen, Tau, Rosenkilde, Mette M

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GLP‑1 Val8: A Biased GLP‑1R Agonist with Altered Binding Kinetics and Impaired Release of Pancreatic Hormones in Rats von van der Velden, Wijnand J. C, Smit, Florent X, Christiansen, Charlotte B, Møller, Thor C, Hjortø, Gertrud M, Larsen, Olav, Schiellerup, Sine P, Bräuner-Osborne, Hans, Holst, Jens J, Hartmann, Bolette, Frimurer, Thomas M, Rosenkilde, Mette M

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Human cytomegalovirus chemokine receptor US28 induces migration of cells on a CX3CL1-presenting surface von Hjortø, Gertrud M, Kiilerich-Pedersen, Katrine, Selmeczi, David, Kledal, Thomas N, Larsen, Niels B

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Differential CCR7 Targeting in Dendritic Cells by Three Naturally Occurring CC-Chemokines von Hjortø, Gertrud M, Larsen, Olav, Steen, Anne, Daugvilaite, Viktorija, Berg, Christian, Fares, Suzan, Hansen, Morten, Ali, Simi, Rosenkilde, Mette M

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Generating substrate bound functional chemokine gradients in vitro von Hjortø, Gertrud M, Hansen, Morten, Larsen, Niels B, Kledal, Thomas N

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Cell culture plastics with immobilized interleukin-4 for monocyte differentiation von Hansen, Morten, Hjortø, Gertrud M., Met, Özcan, Jakobsen, Mogens H., Svane, Inge M., Larsen, Niels B.

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Factor VIIa/tissue factor-dependent gene regulation and pro-coagulant activity: Effect of factor VIIa concentration von Petersen, Lars C, Albrektsen, Tatjana, Hjortø, Gertrud M, Kjalke, Marianne, Bjørn, Søren E, Sørensen, Brit B

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Viral GPCR US28 can signal in response to chemokine agonists of nearly unlimited structural degeneracy von Miles, Timothy F, Spiess, Katja, Jude, Kevin M, Tsutsumi, Naotaka, Burg, John S, Ingram, Jessica R, Waghray, Deepa, Hjorto, Gertrud M, Larsen, Olav, Ploegh, Hidde L, Rosenkilde, Mette M, Garcia, K Christopher

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Corrigendum: Differential CCR7 Targeting in Dendritic Cells by Three Naturally Occurring CC-Chemokines von Hjortø, Gertrud M, Larsen, Olav, Steen, Anne, Daugvilaite, Viktorija, Berg, Christian, Fares, Suzan, Hansen, Morten, Ali, Simi, Rosenkilde, Mette M

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