The first-in-class ERK inhibitor ulixertinib shows promising activity in mitogen-activated protein kinase (MAPK)-driven pediatric low-grade glioma models von Sigaud, Romain, Rösch, Lisa, Gatzweiler, Charlotte, Benzel, Julia, von Soosten, Laura, Peterziel, Heike, Selt, Florian, Najafi, Sara, Ayhan, Simay, Gerloff, Xenia F, Hofmann, Nina, Büdenbender, Isabel, Schmitt, Lukas, Foerster, Kathrin I, Burhenne, Jürgen, Haefeli, Walter E, Korshunov, Andrey, Sahm, Felix, van Tilburg, Cornelis M, Jones, David T W, Pfister, Stefan M, Knoerzer, Deborah, Kreider, Brent L, Sauter, Max, Pajtler, Kristian W, Zuckermann, Marc, Oehme, Ina, Witt, Olaf, Milde, Till

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Analytical Post-Embedding Immunogold-Electron Microscopy with Direct Gold-Labelled Monoclonal Primary Antibodies against RIBEYE A- and B-Domain Suggests a Refined Model of Synaptic... von Papadopoulos, Stella, Tinschert, René, Papadopoulos, Iason, Gerloff, Xenia, Schmitz, Frank

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Functional Therapeutic Target Validation Using Pediatric Zebrafish Xenograft Models von Gatzweiler, Charlotte, Ridinger, Johannes, Herter, Sonja, Gerloff, Xenia F, ElHarouni, Dina, Berker, Yannick, Imle, Roland, Schmitt, Lukas, Kreth, Sina, Stainczyk, Sabine, Ayhan, Simay, Najafi, Sara, Krunic, Damir, Frese, Karen, Meder, Benjamin, Reuss, David, Fiesel, Petra, Schramm, Kathrin, Blattner-Johnson, Mirjam, Jones, David T W, Banito, Ana, Westermann, Frank, Oppermann, Sina, Milde, Till, Peterziel, Heike, Witt, Olaf, Oehme, Ina

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Broad-Spectrum HDAC Inhibitors Promote Autophagy through FOXO Transcription Factors in Neuroblastoma von Körholz, Katharina, Ridinger, Johannes, Krunic, Damir, Najafi, Sara, Gerloff, Xenia F, Frese, Karen, Meder, Benjamin, Peterziel, Heike, Vega-Rubin-de-Celis, Silvia, Witt, Olaf, Oehme, Ina

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Combining APR-246 and HDAC-Inhibitors: A Novel Targeted Treatment Option for Neuroblastoma von Müller, Michael, Rösch, Lisa, Najafi, Sara, Gatzweiler, Charlotte, Ridinger, Johannes, Gerloff, Xenia F., Jones, David T. W., Baßler, Jochen, Kreth, Sina, Stainczyk, Sabine, Frese, Karen, Meder, Benjamin, Westermann, Frank, Milde, Till, Peterziel, Heike, Witt, Olaf, Oehme, Ina

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Drug sensitivity profiling of 3D tumor tissue cultures in the pediatric precision oncology program INFORM von Peterziel, Heike, Jamaladdin, Nora, ElHarouni, Dina, Gerloff, Xenia F., Herter, Sonja, Fiesel, Petra, Berker, Yannick, Blattner-Johnson, Mirjam, Schramm, Kathrin, Jones, Barbara C., Reuss, David, Turunen, Laura, Friedenauer, Aileen, Holland-Letz, Tim, Sill, Martin, Weiser, Lena, Previti, Christopher, Balasubramanian, Gnanaprakash, Gerber, Nicolas U., Gojo, Johannes, Hutter, Caroline, Øra, Ingrid, Lohi, Olli, Kattamis, Antonis, de Wilde, Bram, Westermann, Frank, Tippelt, Stephan, Graf, Norbert, Nathrath, Michaela, Sparber-Sauer, Monika, Sehested, Astrid, Kramm, Christof M., Dirksen, Uta, Kallioniemi, Olli, Pfister, Stefan M., van Tilburg, Cornelis M., Jones, David T. W., Saarela, Jani, Pietiäinen, Vilja, Jäger, Natalie, Schlesner, Matthias, Kopp-Schneider, Annette, Oppermann, Sina, Milde, Till, Witt, Olaf, Oehme, Ina

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OTHR-04. DEVELOPMENT OF A FUNCTIONAL PLATFORM FOR REAL-TIME PERSONALIZED DRUG SENSITIVITY PROFILING OF PATIENT-DERIVED 3D FRESH TUMOR TISSUE CULTURES IN THE PEDIATRIC PRECISION ONC... von Peterziel, Heike, Jamaladdin, Nora, ElHarouni, Dina, Gerloff, Xenia F, Herter, Sonja, Fiesel, Petra, Berker, Yannick, Blattner-Johnson, Mirjam, Schramm, Kathrin, Jones, Barbara C, Reuss, David, Turunen, Laura, Friedenauer, Aileen, Holland-Letz, Tim, Sill, Martin, Weiser, Lena, Previti, Christopher, Balasubramanian, Gnanaprakash, Gerber, Nicolas U, Gojo, Johannes, Hutter, Caroline, Øra, Ingrid, Lohi, Olli, Kattamis, Antonis, de Wilde, Bram, Westermann, Frank, Tippelt, Stephan, Graf, Norbert, Nathrath, Michaela, Sparber-Sauer, Monika, Sehested, Astrid, Kramm, Christof M, Dirksen, Uta, Kallioniemi, Olli, Pfister, Stefan M, van Tilburg, Cornelis M, Jones, David T W, Saarela, Jani, Pietiäinen, Vilja, Jäger, Natalie, Schlesner, Matthias, Kopp-Schneider, Annette, Oppermann, Sina, Milde, Till, Witt, Olaf, Oehme, Ina

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Drug sensitivity profiling of 3D tumor tissue cultures in the pediatric precision oncology program INFORM von Peterziel, Heike, Jamaladdin, Nora, ElHarouni, Dina, Gerloff, Xenia F, Herter, Sonja, Fiesel, Petra, Berker, Yannick, Blattner-Johnson, Mirjam, Schramm, Kathrin, Jones, Barbara C, Reuss, David, Turunen, Laura, Friedenauer, Aileen, Holland-Letz, Tim, Sill, Martin, Weiser, Lena, Previti, Christopher, Balasubramanian, Gnanaprakash, Gerber, Nicolas U, Gojo, Johannes, Hutter, Caroline, Øra, Ingrid, Lohi, Olli, Kattamis, Antonis, de Wilde, Bram, Westermann, Frank, Tippelt, Stephan, Graf, Norbert, Nathrath, Michaela, Sparber-Sauer, Monika

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Drug sensitivity profiling of 3D tumor tissue cultures in the pediatric precision oncology program INFORM von Peterziel, Heike, Jamaladdin, Nora, ElHarouni, Dina, Gerloff, Xenia F, Herter, Sonja, Fiesel, Petra, Berker, Yannick, Blattner-Johnson, Mirjam, Schramm, Kathrin, Jones, Barbara C, Reuss, David, Turunen, Laura, Friedenauer, Aileen, Holland-Letz, Tim, Sill, Martin, Weiser, Lena, Previti, Christopher, Balasubramanian, Gnanaprakash, Gerber, Nicolas U, Gojo, Johannes, Hutter, Caroline, Øra, Ingrid, Lohi, Olli, Kattamis, Antonis, De Wilde, Bram, Westermann, Frank, Tippelt, Stephan, Graf, Norbert, Nathrath, Michaela, Sparber-Sauer, Monika, Sehested, Astrid, Kramm, Christof M, Dirksen, Uta, Kallioniemi, Olli, Pfister, Stefan M, van Tilburg, Cornelis M, Jones, David T. W, Saarela, Jani, Pietiäinen, Vilja, Jäger, Natalie, Schlesner, Matthias, Kopp-Schneider, Annette, Oppermann, Sina, Milde, Till, Witt, Olaf, Oehme, Ina

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