439 Metabolite-driven regulation of T cells in human keratinocyte-derived skin cancer von Bopp, L., Seitz, R., Huerta Arana, M., Klapproth, H., Cherevatenko, M., Georgomanolis, T., Brodesser, S., Frezza, C., Klein Geltink, R., Fabri, M.

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Investigations in plaque erosion and ruptured in acute coronary syndromes via novel methods in multimodal and VDJ sequencing von De Vore, L, Gerhart, T, Abdelwahed, Y, Stapmanns, P, Wolfram, C, Becker, K, Franitz, M, Georgomanolis, T, Landmesser, U, Leistner, D, Winkels, H

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Monoallelic and biallelic variants in LEF1 are associated with a new syndrome combining ectodermal dysplasia and limb malformations caused by altered WNT signaling von Dufour, William, Alawbathani, Salem, Jourdain, Anne-Sophie, Asif, Maria, Baujat, Geneviève, Becker, Christian, Budde, Birgit, Gallacher, Lyndon, Georgomanolis, Theodoros, Ghoumid, Jamal, Höhne, Wolfgang, Lyonnet, Stanislas, Ba-Saddik, Iman Ali, Manouvrier-Hanu, Sylvie, Motameny, Susanne, Noegel, Angelika A., Pais, Lynn, Vanlerberghe, Clémence, Wagle, Prerana, White, Susan M., Willems, Marjolaine, Nürnberg, Peter, Escande, Fabienne, Petit, Florence, Hussain, Muhammad Sajid

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Autophagy regulator ATG5 maintains cerebellar function by preventing its excessive glycolytic activity von Tutas, Janine, Kononenko, Natalia L.

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Long‐lived macrophage reprogramming drives spike protein‐mediated inflammasome activation in COVID‐19 von Theobald, Sebastian J, Simonis, Alexander, Georgomanolis, Theodoros, Kreer, Christoph, Zehner, Matthias, Eisfeld, Hannah S, Albert, Marie‐Christine, Chhen, Jason, Motameny, Susanne, Erger, Florian, Fischer, Julia, Malin, Jakob J, Gräb, Jessica, Winter, Sandra, Pouikli, Andromachi, David, Friederike, Böll, Boris, Koehler, Philipp, Vanshylla, Kanika, Gruell, Henning, Suárez, Isabelle, Hallek, Michael, Fätkenheuer, Gerd, Jung, Norma, Cornely, Oliver A, Lehmann, Clara, Tessarz, Peter, Altmüller, Janine, Nürnberg, Peter, Kashkar, Hamid, Klein, Florian, Koch, Manuel, Rybniker, Jan

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HMGB1 coordinates SASP‐related chromatin folding and RNA homeostasis on the path to senescence von Sofiadis, Konstantinos, Josipovic, Natasa, Nikolic, Milos, Kargapolova, Yulia, Übelmesser, Nadine, Varamogianni‐Mamatsi, Vassiliki, Zirkel, Anne, Papadionysiou, Ioanna, Loughran, Gary, Keane, James, Michel, Audrey, Gusmao, Eduardo G, Becker, Christian, Altmüller, Janine, Georgomanolis, Theodore, Mizi, Athanasia, Papantonis, Argyris

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Tissue-specific adaptations to cytochrome c oxidase deficiency shape physiological outcomes von Popovic, Milica, Isermann, Lea, Geißen, Simon, Senft, Katharina, Georgomanolis, Theodoros, Baldus, Stephan, Frezza, Christian, Trifunovic, Aleksandra

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Cutting a Long Intron Short: Recursive Splicing and Its Implications von Georgomanolis, Theodore, Sofiadis, Konstantinos, Papantonis, Argyris

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DNA methylation changes during long-term in vitro cell culture are caused by epigenetic drift von Franzen, Julia, Georgomanolis, Theodoros, Selich, Anton, Kuo, Chao-Chung, Stöger, Reinhard, Brant, Lilija, Mulabdić, Melita Sara, Fernandez-Rebollo, Eduardo, Grezella, Clara, Ostrowska, Alina, Begemann, Matthias, Nikolić, Miloš, Rath, Björn, Ho, Anthony D., Rothe, Michael, Schambach, Axel, Papantonis, Argyris, Wagner, Wolfgang

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Exploiting native forces to capture chromosome conformation in mammalian cell nuclei von Brant, Lilija, Georgomanolis, Theodore, Nikolic, Milos, Brackley, Chris A, Kolovos, Petros, van Ijcken, Wilfred, Grosveld, Frank G, Marenduzzo, Davide, Papantonis, Argyris

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GemC1 is a critical switch for neural stem cell generation in the postnatal brain von Lalioti, Maria‐Eleni, Kaplani, Konstantina, Lokka, Georgia, Georgomanolis, Theodore, Kyrousi, Christina, Dong, Weilai, Dunbar, Ashley, Parlapani, Evangelia, Damianidou, Eleni, Spassky, Nathalie, Kahle, Kristopher T., Papantonis, Argyris, Lygerou, Zoi, Taraviras, Stavros

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Maternal and perinatal obesity induce bronchial obstruction and pulmonary hypertension via IL-6-FoxO1-axis in later life von Selle, Jaco, Dinger, Katharina, Jentgen, Vanessa, Zanetti, Daniela, Will, Johannes, Georgomanolis, Theodoros, Vohlen, Christina, Wilke, Rebecca, Kojonazarov, Baktybek, Klymenko, Oleksiy, Mohr, Jasmine, v. Koningsbruggen-Rietschel, Silke, Rhodes, Christopher J., Ulrich, Anna, Hirani, Dharmesh, Nestler, Tim, Odenthal, Margarete, Mahabir, Esther, Nayakanti, Sreenath, Dabral, Swati, Wunderlich, Thomas, Priest, James, Seeger, Werner, Dötsch, Jörg, Pullamsetti, Soni S., Alejandre Alcazar, Miguel A.

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HMGB2 Loss upon Senescence Entry Disrupts Genomic Organization and Induces CTCF Clustering across Cell Types von Zirkel, Anne, Nikolic, Milos, Sofiadis, Konstantinos, Mallm, Jan-Philipp, Brackley, Chris A., Gothe, Henrike, Drechsel, Oliver, Becker, Christian, Altmüller, Janine, Josipovic, Natasa, Georgomanolis, Theodore, Brant, Lilija, Franzen, Julia, Koker, Mirjam, Gusmao, Eduardo G., Costa, Ivan G., Ullrich, Roland T., Wagner, Wolfgang, Roukos, Vassilis, Nürnberg, Peter, Marenduzzo, Davide, Rippe, Karsten, Papantonis, Argyris

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Exposing INSPIRE on the Semantic Web von Patroumpas, K., Georgomanolis, N., Stratiotis, T., Alexakis, M., Athanasiou, S.

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GemC1 governs multiciliogenesis through direct interaction with and transcriptional regulation of p73 von Lalioti, Maria-Eleni, Arbi, Marina, Loukas, Ioannis, Kaplani, Konstantina, Kalogeropoulou, Argyro, Lokka, Georgia, Kyrousi, Christina, Mizi, Athanasia, Georgomanolis, Theodore, Josipovic, Natasa, Gkikas, Dimitrios, Benes, Vladimir, Politis, Panagiotis K, Papantonis, Argyris, Lygerou, Zoi, Taraviras, Stavros

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Extracellular vesicles and PD-L1 suppress macrophages inducing therapy resistance in TP53-deficient B-cell malignancies von Izquierdo, Elena, Vorholt, Daniela, Blakemore, Stuart, Sackey, Benedict, Nolte, Janica L., Barbarino, Verena, Schmitz, Jan, Nickel, Nadine, Bachurski, Daniel, Lobastova, Liudmila, Nikolic, Milos, Michalik, Michael, Brinker, Reinhild, Merkel, Olaf, Franitza, Marek, Georgomanolis, Theodoros, Neuhaus, René, Koch, Maximilian, Nasada, Niklas, Knittel, Gero, Chapuy, Björn, Ludwig, Nicole, Meese, Eckart, Frenzel, Lukas, Reinhardt, Hans Christian, Peifer, Martin, Rebollido-Rios, Rocio, Bruns, Heiko, Krüger, Marcus, Hallek, Michael, Pallasch, Christian

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yylncT Defines a Class of Divergently Transcribed lncRNAs and Safeguards the T-mediated Mesodermal Commitment of Human PSCs von Frank, Stefan, Ahuja, Gaurav, Bartsch, Deniz, Russ, Nicole, Yao, Wenjie, Kuo, Joseph Chao-Chung, Derks, Jens-Peter, Akhade, Vijay Suresh, Kargapolova, Yulia, Georgomanolis, Theodore, Messling, Jan-Erik, Gramm, Marie, Brant, Lilija, Rehimi, Rizwan, Vargas, Natalia Emilse, Kuroczik, Alina, Yang, Tsun-Po, Sahito, Raja Ghazanfar Ali, Franzen, Julia, Hescheler, Juergen, Sachinidis, Agapios, Peifer, Martin, Rada-Iglesias, Alvaro, Kanduri, Meena, Costa, Ivan G., Kanduri, Chandrasekhar, Papantonis, Argyris, Kurian, Leo

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NIK/MAP3K14 in hepatocytes orchestrates NASH to hepatocellular carcinoma progression via JAK2/STAT5 inhibition von Vesting, Anna Juliane, Jais, Alexander, Klemm, Paul, Steuernagel, Lukas, Wienand, Peter, Fog-Tonnesen, Morten, Hvid, Henning, Schumacher, Anna–Lena, Kukat, Christian, Nolte, Hendrik, Georgomanolis, Theodoros, Altmüller, Janine, Pasparakis, Manolis, Schmidt, Andreas, Krüger, Marcus, Supprian, Marc Schmidt, Waisman, Ari, Straub, Beate Katharina, Raschzok, Nathanael, Bernier, Michel, Birkenfeld, Andreas L., Hövelmeyer, Nadine, Brüning, Jens C., Wunderlich, F. Thomas

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Remodeling of the endothelial cell transcriptional program via paracrine and DNA-binding activities of MPO von Zheng, Ruiyuan, Moynahan, Kyle, Georgomanolis, Theodoros, Pavlenko, Egor, Geissen, Simon, Mizi, Athanasia, Grimm, Simon, Nemade, Harshal, Rehimi, Rizwan, Bastigkeit, Jil, Lackmann, Jan-Wilm, Adam, Matti, Rada-Iglesias, Alvaro, Nuernberg, Peter, Klinke, Anna, Poepsel, Simon, Baldus, Stephan, Papantonis, Argyris, Kargapolova, Yulia

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Splicing of many human genes involves sites embedded within introns von Kelly, Steven, Georgomanolis, Theodore, Zirkel, Anne, Diermeier, Sarah, O'Reilly, Dawn, Murphy, Shona, Längst, Gernot, Cook, Peter R, Papantonis, Argyris

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