Quantitative Profiling Method for Oxylipin Metabolome by Liquid Chromatography Electrospray Ionization Tandem Mass Spectrometry von Yang, Jun, Schmelzer, Kara, Georgi, Katrin, Hammock, Bruce D.

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Individual variation in lipidomic profiles of healthy subjects in response to omega-3 Fatty acids von Nording, Malin L, Yang, Jun, Georgi, Katrin, Hegedus Karbowski, Christine, German, J Bruce, Weiss, Robert H, Hogg, Ronald J, Trygg, Johan, Hammock, Bruce D, Zivkovic, Angela M

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Discovery of Potent, Orally Bioavailable, Small-Molecule Inhibitors of WNT Signaling from a Cell-Based Pathway Screen von Mallinger, Aurélie, Crumpler, Simon, Pichowicz, Mark, Waalboer, Dennis, Stubbs, Mark, Adeniji-Popoola, Olajumoke, Wood, Bozena, Smith, Elizabeth, Thai, Ching, Henley, Alan T, Georgi, Katrin, Court, William, Hobbs, Steve, Box, Gary, Ortiz-Ruiz, Maria-Jesus, Valenti, Melanie, De Haven Brandon, Alexis, TePoele, Robert, Leuthner, Birgitta, Workman, Paul, Aherne, Wynne, Poeschke, Oliver, Dale, Trevor, Wienke, Dirk, Esdar, Christina, Rohdich, Felix, Raynaud, Florence, Clarke, Paul A, Eccles, Suzanne A, Stieber, Frank, Schiemann, Kai, Blagg, Julian

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Soluble epoxide hydrolase and epoxyeicosatrienoic acids modulate two distinct analgesic pathways von Inceoglu, Bora, Jinks, Steven L, Ulu, Arzu, Hegedus, Christine M, Georgi, Katrin, Schmelzer, Kara R, Wagner, Karen, Jones, Paul D, Morisseau, Christophe, Hammock, Bruce D

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Changes in PTGS1 and ALOX12 Gene Expression in Peripheral Blood Mononuclear Cells Are Associated with Changes in Arachidonic Acid, Oxylipins, and Oxylipin/Fatty Acid Ratios in Resp... von Berthelot, Claire C, Kamita, Shizuo George, Sacchi, Romina, Yang, Jun, Nording, Malin L, Georgi, Katrin, Hegedus Karbowski, Christine, German, J Bruce, Weiss, Robert H, Hogg, Ronald J, Hammock, Bruce D, Zivkovic, Angela M

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Altered Soluble Epoxide Hydrolase Gene Expression and Function and Vascular Disease Risk in the Stroke-Prone Spontaneously Hypertensive Rat von Corenblum, Mandi J, Wise, Vance E, Georgi, Katrin, Hammock, Bruce D, Doris, Peter A, Fornage, Myriam

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Serum oxylipin profiles in IgA nephropathy patients reflect kidney functional alterations von Zivkovic, Angela M., Yang, Jun, Georgi, Katrin, Hegedus, Christine, Nording, Malin L., O’Sullivan, Aifric, German, J. Bruce, Hogg, Ronald J., Weiss, Robert H., Bay, Curt, Hammock, Bruce D.

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Multi-Well Array Culture of Primary Human Hepatocyte Spheroids for Clearance Extrapolation of Slowly Metabolized Compounds von Preiss, Lena C., Lauschke, Volker M., Georgi, Katrin, Petersson, Carl

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Crystalline Sponges as a Sensitive and Fast Method for Metabolite Identification: Application to Gemfibrozil and its Phase I and II Metabolites von Rosenberger, Lara, von Essen, Carolina, Khutia, Anupam, Kuehn, Clemens, Urbahns, Klaus, Georgi, Katrin, Hartmann, Rolf W., Badolo, Lassina

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Considerations for Human ADME Strategy and Design Paradigm Shift(s) – An Industry White Paper von Young, Graeme C., Spracklin, Douglas K., James, Alexander D., Hvenegaard, Mette G., Scarfe, Graeme, Wagner, David S., Georgi, Katrin, Schieferstein, Hanno, Bjornsdottir, Inga, Groen, Bianca, Romeo, Andrea A., Cassidy, Kenneth C., Da‐violante, Georges, Bister, Bojan, Blech, Stefan, Lyer, Ramaswamy, Schulz, Simone I., Cuyckens, Filip, Moliner, Patricia

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Deconvolution of Cytochrome P450 Induction Mechanisms in HepaRG Nuclear Hormone Receptor Knockout Cells von Preiss, Lena C., Liu, Ruoqi, Hewitt, Philip, Thompson, David, Georgi, Katrin, Badolo, Lassina, Lauschke, Volker M., Petersson, Carl

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Metabolic Profiling of S -praziquantel: Structure Elucidation Using the Crystalline Sponge Method in Combination with Mass Spectrometry and Nuclear Magnetic Resonance von Rosenberger, Lara, Jenniches, Judith, von Essen, Carolina, Khutia, Anupam, Kühn, Clemens, Marx, Andreas, Georgi, Katrin, Hirsch, Anna K H, Hartmann, Rolf W, Badolo, Lassina

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Crystalline sponge affinity screening: A fast tool for soaking condition optimization without the need of X-ray diffraction analysis von Rosenberger, Lara, von Essen, Carolina, Khutia, Anupam, Kühn, Clemens, Georgi, Katrin, Hirsch, Anna K.H., Hartmann, Rolf W., Badolo, Lassina

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Non‐Labeled, Stable Labeled, or Radiolabelled Approaches for Provision of Intravenous Pharmacokinetics in Humans: A Discussion Piece von Young, Graeme C., Spracklin, Douglas K., James, Alexander D., Hvenegaard, Mette G., Pedersen, Mette L., Wagner, David S., Georgi, Katrin, Schieferstein, Hanno, Bjornsdottir, Inga, Romeo, Andrea A., Cassidy, Kenneth C., Da‐violante, Georges, Blech, Stefan, Schulz, Simone I., Cuyckens, Filip, Nguyen, Mai Anh, Scarfe, Graeme

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Identification of Clinical Candidate M2698, a Dual p70S6K and Akt Inhibitor, for Treatment of PAM Pathway-Altered Cancers von DeSelm, Lizbeth, Huck, Bayard, Lan, Ruoxi, Neagu, Constantin, Potnick, Justin, Xiao, Yufang, Chen, Xiaoling, Jones, Reinaldo, Richardson, Thomas E, Heasley, Brian H, Haxell, Thomas, Moore, Joseph, Tian, Hui, Georgi, Katrin, Rohdich, Felix, Sutton, Amanda, Johnson, Theresa, Mochalkin, Igor, Jackson, Jennifer, Lin, Jing, Crowley, Lindsey, Machl, Andreas, Clark, Anderson, Wilker, Erik, Sherer, Brian, Goutopoulos, Andreas

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Discovery of Covalent Bruton's Tyrosine Kinase Inhibitors with Decreased CYP2C8 Inhibitory Activity von Qiu, Hui, Ali, Zahid, Bowlan, Julian, Caldwell, Richard, Gardberg, Anna, Glaser, Nina, Goutopoulos, Andreas, Head, Jared, Johnson, Theresa, Maurer, Christine, Georgi, Katrin, Grenningloh, Roland, Fang, Zhizhou, Morandi, Federica, Rohdich, Felix, Schmidt, Ralf, Follis, Ariele Viacava, Sherer, Brian

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Increasing the Reuse of Protein Non-Naïve Nonhuman Primates in Pharmaceutical Drug Discovery and Development: An Overview and Industry Position on the Challenges and Benefits von Mattis, Charles, Bratcher, Natalie, Burns, Monika, Carosino, Christopher, de Zafra, Christina, Fancher, R. Marcus, Georgi, Katrin, Graff, Candace, Hukkanen, Renee R., Johnson, Colena, Lao, Yanbin, Lange, Amber, Lee, Donna, Lepherd, Michelle, Maguire, Sean, Malisauskas, Mantas, Manuel, Melinda, Miranda, Sonia, Reed, Lori, Santos, Rosemary, Sayers, Brian, Shaw, David, Shuster, David

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Serum oxylipin profiles in IgA nephropathy patients reflect kidney functional alterations von Zivkovic, Angela M., Yang, Jun, Georgi, Katrin, Hegedus, Christine, Nording, Malin L., O’Sullivan, Aifric, German, J. Bruce, Hogg, Ronald J., Weiss, Robert H., Bay, Curt, Hammock, Bruce D.

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Identification and Optimization of an Aminoalcohol-Carbazole Series with Antimalarial Properties von Molette, Jérôme, Routier, Julie, Abla, Nada, Besson, Dominique, Bombrun, Agnes, Brun, Reto, Burt, Howard, Georgi, Katrin, Kaiser, Marcel, Nwaka, Solomon, Muzerelle, Mathilde, Scheer, Alexander

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Epoxy‐Fatty Amides and Esters as Substrates for Human sEH von Georgi, Katrin, Morisseau, Christophe, Huang, Huazhang, Hammock, Bruce D

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