Mechanism of asymmetric polymerase assembly at the eukaryotic replication fork von Georgescu, Roxana E, Langston, Lance, Yao, Nina Y, Yurieva, Olga, Zhang, Dan, Finkelstein, Jeff, Agarwal, Tani, O'Donnell, Mike E

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CMG helicase and DNA polymerase ε form a functional 15-subunit holoenzyme for eukaryotic leading-strand DNA replication von Langston, Lance D., Zhang, Dan, Yurieva, Olga, Georgescu, Roxana E., Finkelstein, Jeff, Yao, Nina Y., Indiani, Chiara, O'Donnell, Mike E.

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DNA is loaded through the 9-1-1 DNA checkpoint clamp in the opposite direction of the PCNA clamp von Zheng, Fengwei, Georgescu, Roxana E., Yao, Nina Y., O’Donnell, Michael E., Li, Huilin

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Structures of 9-1-1 DNA checkpoint clamp loading at gaps from start to finish and ramification on biology von Zheng, Fengwei, Georgescu, Roxana E., Yao, Nina Y., O’Donnell, Michael E., Li, Huilin

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Mcm10 promotes rapid isomerization of CMG-DNA for replisome bypass of lagging strand DNA blocks von Langston, Lance D, Mayle, Ryan, Schauer, Grant D, Yurieva, Olga, Zhang, Daniel, Yao, Nina Y, Georgescu, Roxana E, O'Donnell, Mike E

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Reconstitution of a eukaryotic replisome reveals suppression mechanisms that define leading/lagging strand operation von Georgescu, Roxana E, Schauer, Grant D, Yao, Nina Y, Langston, Lance D, Yurieva, Olga, Zhang, Dan, Finkelstein, Jeff, O'Donnell, Mike E

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A solution to release twisted DNA during chromosome replication by coupled DNA polymerases von Kurth, Isabel, Georgescu, Roxana E., O'Donnell, Mike E.

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Single-Molecule Analysis Reveals That the Lagging Strand Increases Replisome Processivity but Slows Replication Fork Progression von Yao, Nina Y., Georgescu, Roxana E., Finkelstein, Jeff, O'Donnell, Michael E.

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Structure of eukaryotic DNA polymerase δ bound to the PCNA clamp while encircling DNA von Zheng, Fengwei, Georgescu, Roxana E., Li, Huilin, O’Donnell, Michael E.

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Structure of a Small-Molecule Inhibitor of a DNA Polymerase Sliding Clamp von Georgescu, Roxana E., Yurieva, Olga, Kim, Seung-Sup, Kuriyan, John, Kong, Xiang-Peng, O'Donnell, Mike

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Mechanism of eukaryotic origin unwinding is a dual helicase DNA shearing process von Langston, Lance D, Georgescu, Roxana E, O'Donnell, Michael E

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The architecture of a eukaryotic replisome von Sun, Jingchuan, Shi, Yi, Georgescu, Roxana E, Yuan, Zuanning, Chait, Brian T, Li, Huilin, O'Donnell, Michael E

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Mechanism of polymerase collision release from sliding clamps on the lagging strand von Georgescu, Roxana E, Kurth, Isabel, Yao, Nina Y, Stewart, Jelena, Yurieva, Olga, O'Donnell, Mike

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Single-molecule studies reveal the function of a third polymerase in the replisome von Georgescu, Roxana E, Kurth, Isabel, O'Donnell, Mike E

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The DnaC helicase loader is a dual ATP/ADP switch protein von Davey, Megan J., Fang, Linhua, McInerney, Peter, Georgescu, Roxana E., O'Donnell, Mike

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Combining Conformational Flexibility and Continuum Electrostatics for Calculating pKas in Proteins von Georgescu, Roxana E., Alexov, Emil G., Gunner, Marilyn R.

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A Peptide Switch Regulates DNA Polymerase Processivity von Francisco J. López de Saro, Georgescu, Roxana E., O'Donnell, Mike

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Structure of a Sliding Clamp on DNA von Georgescu, Roxana E., Kim, Seung-Sup, Yurieva, Olga, Kuriyan, John, Kong, Xiang-Peng, O'Donnell, Mike

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Replisome mechanics: lagging strand events that influence speed and processivity von Georgescu, Roxana E, Yao, Nina, Indiani, Chiara, Yurieva, Olga, O'Donnell, Mike E

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Crystal Structure of the Catalytic α Subunit of E. coli Replicative DNA Polymerase III von Lamers, Meindert H., Georgescu, Roxana E., Lee, Sang-Gyu, O'Donnell, Mike, Kuriyan, John

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