Genetic, transcriptional and post-translational regulation of the programmed death protein ligand 1 in cancer: biology and clinical correlations von Zerdes, Ioannis, Matikas, Alexios, Bergh, Jonas, Rassidakis, George Z., Foukakis, Theodoros

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AP-1 Transcription Factors as Regulators of Immune Responses in Cancer von Atsaves, Vasileios, Leventaki, Vasiliki, Rassidakis, George Z, Claret, Francois X

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Programmed death‐ligand 1 gene expression is a prognostic marker in early breast cancer and provides additional prognostic value to 21‐gene and 70‐gene signatures in estrogen recep... von Zerdes, Ioannis, Sifakis, Emmanouil G., Matikas, Alexios, Chrétien, Sebastian, Tobin, Nicholas P., Hartman, Johan, Rassidakis, George Z., Bergh, Jonas, Foukakis, Theodoros

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mTOR signaling is activated by FLT3 kinase and promotes survival of FLT3-mutated acute myeloid leukemia cells von Chen, Weina, Drakos, Elias, Grammatikakis, Ioannis, Schlette, Ellen J, Li, Jiang, Leventaki, Vasiliki, Staikou-Drakopoulou, Efi, Patsouris, Efstratios, Panayiotidis, Panayiotis, Medeiros, L Jeffrey, Rassidakis, George Z

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Expression of Somatostatin Receptors 1-5 and Dopamine Receptor 2 in Lung Carcinoids: Implications for a Therapeutic Role von Kanakis, George, Grimelius, Lars, Spathis, Athanasios, Tringidou, Rodoula, Rassidakis, George Z., Öberg, Kjell, Kaltsas, Gregory, Tsolakis, Apostolos V.

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Activation of mammalian target of rapamycin signaling pathway contributes to tumor cell survival in anaplastic lymphoma kinase-positive anaplastic large cell lymphoma von Vega, Francisco, Medeiros, L Jeffrey, Leventaki, Vasiliki, Atwell, Coralyn, Cho-Vega, Jeong Hee, Tian, Ling, Claret, Francois-Xavier, Rassidakis, George Z

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Survivin Expression Predicts Poorer Prognosis in Anaplastic Large-Cell Lymphoma von SCHLETTE, Ellen J, MEDEIROS, L. Jeffrey, GOY, Andre, LAI, Raymond, RASSIDAKIS, George Z

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SIN1, a critical component of the mTOR-Rictor complex, is overexpressed and associated with AKT activation in medullary and aggressive papillary thyroid carcinomas von Moraitis, Dimitrios, MD, PhD, Karanikou, Maria, BSc, Liakou, Chryssa, MD, Dimas, Konstantinos, PhD, Tzimas, George, MD, Tseleni-Balafouta, Sofia, MD, Patsouris, Efstratios, MD, Rassidakis, George Z., MD, PhD, Kouvaraki, Maria A., MD, PhD

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c-JUN N-terminal kinase (JNK) is activated and contributes to tumor cell proliferation in classical Hodgkin lymphoma von Leventaki, Vasiliki, MD, Drakos, Elias, MD, PhD, Karanikou, Maria, MSc, Psatha, Konstantina, MSc, Lin, Pei, MD, Schlette, Ellen, MD, Eliopoulos, Aris, PhD, Vassilakopoulos, Theodoros P., MD, PhD, Papadaki, Helen, MD, PhD, Patsouris, Efstratios, MD, PhD, Medeiros, L. Jeffrey, MD, Rassidakis, George Z., MD, PhD

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NPM-ALK oncogenic kinase promotes cell-cycle progression through activation of JNK/cJun signaling in anaplastic large-cell lymphoma von Leventaki, Vasiliki, Drakos, Elias, Medeiros, L. Jeffrey, Lim, Megan S., Elenitoba-Johnson, Kojo S., Claret, Francois X., Rassidakis, George Z.

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Inhibition of p53-Murine Double Minute 2 Interaction by Nutlin-3A Stabilizes p53 and Induces Cell Cycle Arrest and Apoptosis in Hodgkin Lymphoma von DRAKOS, Elias, THOMAIDES, Athanasios, MEDEIROS, L. Jeffrey, JIANG LI, LEVENTAKI, Vasiliki, KONOPLEVA, Marina, ANDREEFF, Michael, RASSIDAKIS, George Z

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Selective inhibition of STAT3 induces apoptosis and G1 cell cycle arrest in ALK-positive anaplastic large cell lymphoma von AMIN, Hesham M, MCDONNELL, Timothy J, MEDEIROS, L. Jeffrey, LAI, Raymond, MA, Yupo, QUAN LIN, FUJIO, Yasushi, KUNISADA, Keita, LEVENTAKI, Vasiliki, DAS, Pamela, RASSIDAKIS, George Z, CUTLER, Cathy

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Sipa1 deficiency–induced bone marrow niche alterations lead to the initiation of myeloproliferative neoplasm von Xiao, Pingnan, Dolinska, Monika, Sandhow, Lakshmi, Kondo, Makoto, Johansson, Anne-Sofie, Bouderlique, Thibault, Zhao, Ying, Li, Xidan, Dimitriou, Marios, Rassidakis, George Z., Hellström-Lindberg, Eva, Minato, Nagahiro, Walfridsson, Julian, Scadden, David T., Sigvardsson, Mikael, Qian, Hong

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Activation of mTOR signaling in medullary and aggressive papillary thyroid carcinomas von Kouvaraki, Maria A., MD, PhD, Liakou, Chrysoula, MD, Paraschi, Adriani, MSc, Dimas, Konstantinos, PhD, Patsouris, Efstratios, MD, PhD, Tseleni-Balafouta, Sofia, MD, PhD, Rassidakis, George Z., MD, PhD, Moraitis, Dimitrios, MD, PhD

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The proteomic signature of NPM/ALK reveals deregulation of multiple cellular pathways von Lim, Megan S., Carlson, Mary L., Crockett, David K., Fillmore, G. Chris, Abbott, David R., Elenitoba-Johnson, Olaotan F., Tripp, Sheryl R., Rassidakis, George Z., Medeiros, L. Jeffrey, Szankasi, Philippe, Elenitoba-Johnson, Kojo S.J.

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STAT3 Activity Promotes Programmed-Death Ligand 1 Expression and Suppresses Immune Responses in Breast Cancer von Zerdes, Ioannis, Wallerius, Majken, Sifakis, Emmanouil, Wallmann, Tatjana, Betts, Stina, Bartish, Margarita, Tsesmetzis, Nikolaos, Tobin, Nicholas, Coucoravas, Christos, Bergh, Jonas, Rassidakis, George, Rolny, Charlotte, Foukakis, Theodoros

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Inhibition of JAK3 induces apoptosis and decreases anaplastic lymphoma kinase activity in anaplastic large cell lymphoma von AMIND, Hesham M, MEDEIROS, L. Jeffrey, MA, Yupo, FERETZAKI, Marianna, DAS, Pamela, LEVENTAKI, Vasiliki, RASSIDAKIS, George Z, O'CONNOR, Sean L, MCDONNELL, Timothy J, LAI, Raymond

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CD3(-)CD16(-)CD56(bright) immunoregulatory NK cells are increased in the tumor microenvironment and inversely correlate with advanced stages in patients with papillary thyroid canc... von Gogali, Foteini, Paterakis, George, Rassidakis, George Z, Liakou, Chrysoula I, Liapi, Charis

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CD274 (PD‐L1)/PDCD1 (PD‐1) expression in de novo and transformed diffuse large B‐cell lymphoma von Kwiecinska, Anna, Tsesmetzis, Nikolaos, Ghaderi, Mehran, Kis, Lorand, Saft, Leonie, Rassidakis, George Z.

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53BP1 and p53 Synergize to Suppress Genomic Instability and Lymphomagenesis von Morales, Julio C., Franco, Sonia, Murphy, Michael M., Bassing, Craig H., Mills, Kevin D., Adams, Melissa M., Walsh, Nicole C., Manis, John P., Rassidakis, George Z., Alt, Frederick W., Carpenter, Phillip B.

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