Insights to SARS-CoV-2 life cycle, pathophysiology, and rationalized treatments that target COVID-19 clinical complications von Trougakos, Ioannis P, Stamatelopoulos, Kimon, Terpos, Evangelos, Tsitsilonis, Ourania E, Aivalioti, Evmorfia, Paraskevis, Dimitrios, Kastritis, Efstathios, Pavlakis, George N, Dimopoulos, Meletios A

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Evaluating the effects of second-dose vaccine-delay policies in European countries: A simulation study based on data from Greece von Barmpounakis, Petros, Demiris, Nikolaos, Kontoyiannis, Ioannis, Pavlakis, George N, Sypsa, Vana

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Systemic IL-15, IFN-γ, and IP-10/CXCL10 signature associated with effective immune response to SARS-CoV-2 in BNT162b2 mRNA vaccine recipients von Bergamaschi, Cristina, Terpos, Evangelos, Rosati, Margherita, Angel, Matthew, Bear, Jenifer, Stellas, Dimitris, Karaliota, Sevasti, Apostolakou, Filia, Bagratuni, Tina, Patseas, Dimitris, Gumeni, Sentiljana, Trougakos, Ioannis P., Dimopoulos, Meletios A., Felber, Barbara K., Pavlakis, George N.

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Efficient production and enhanced tumor delivery of engineered extracellular vesicles von Watson, Dionysios C, Bayik, Defne, Srivatsan, Avinash, Bergamaschi, Cristina, Valentin, Antonio, Niu, Gang, Bear, Jenifer, Monninger, Mitchell, Sun, Mei, Morales-Kastresana, Aizea, Jones, Jennifer C, Felber, Barbara K, Chen, Xiaoyuan, Gursel, Ihsan, Pavlakis, George N

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Labeling Extracellular Vesicles for Nanoscale Flow Cytometry von Morales-Kastresana, Aizea, Telford, Bill, Musich, Thomas A., McKinnon, Katherine, Clayborne, Cassandra, Braig, Zach, Rosner, Ari, Demberg, Thorsten, Watson, Dionysios C., Karpova, Tatiana S., Freeman, Gordon J., DeKruyff, Rosemarie H., Pavlakis, George N., Terabe, Masaki, Robert-Guroff, Marjorie, Berzofsky, Jay A., Jones, Jennifer C.

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Evaluation of chimeric antigen receptor T cell therapy in non-human primates infected with SHIV or SIV von Iwamoto, Nami, Patel, Bhavik, Song, Kaimei, Mason, Rosemarie, Bolivar-Wagers, Sara, Bergamaschi, Cristina, Pavlakis, George N, Berger, Edward, Roederer, Mario

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Treatment with native heterodimeric IL-15 increases cytotoxic lymphocytes and reduces SHIV RNA in lymph nodes von Watson, Dionysios C, Moysi, Eirini, Valentin, Antonio, Bergamaschi, Cristina, Devasundaram, Santhi, Fortis, Sotirios P, Bear, Jenifer, Chertova, Elena, Bess, Jr, Julian, Sowder, Ray, Venzon, David J, Deleage, Claire, Estes, Jacob D, Lifson, Jeffrey D, Petrovas, Constantinos, Felber, Barbara K, Pavlakis, George N

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Control of SARS-CoV-2 infection after Spike DNA or Spike DNA+Protein co-immunization in rhesus macaques von Rosati, Margherita, Agarwal, Mahesh, Hu, Xintao, Devasundaram, Santhi, Stellas, Dimitris, Chowdhury, Bhabadeb, Bear, Jenifer, Burns, Robert, Donohue, Duncan, Pessaint, Laurent, Andersen, Hanne, Lewis, Mark G, Terpos, Evangelos, Dimopoulos, Meletios Athanasios, Wlodawer, Alexander, Mullins, James I, Venzon, David J, Pavlakis, George N, Felber, Barbara K

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CTL responses of high functional avidity and broad variant cross-reactivity are associated with HIV control von Mothe, Beatriz, Llano, Anuska, Ibarrondo, Javier, Zamarreño, Jennifer, Schiaulini, Mattia, Miranda, Cristina, Ruiz-Riol, Marta, Berger, Christoph T, Herrero, M José, Palou, Eduard, Plana, Montse, Rolland, Morgane, Khatri, Ashok, Heckerman, David, Pereyra, Florencia, Walker, Bruce D, Weiner, David, Paredes, Roger, Clotet, Bonaventura, Felber, Barbara K, Pavlakis, George N, Mullins, James I, Brander, Christian

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Heterodimeric IL-15 delays tumor growth and promotes intratumoral CTL and dendritic cell accumulation by a cytokine network involving XCL1, IFN-γ, CXCL9 and CXCL10 von Bergamaschi, Cristina, Pandit, Hrishikesh, Nagy, Bethany A, Stellas, Dimitris, Jensen, Shawn M, Bear, Jenifer, Cam, Maggie, Valentin, Antonio, Fox, Bernard A, Felber, Barbara K, Pavlakis, George N

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A new step towards an HIV/AIDS vaccine von Pavlakis, George N, Felber, Barbara K

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Sequential Analysis of Binding and Neutralizing Antibody in COVID-19 Convalescent Patients at 14 Months After SARS-CoV-2 Infection von Rosati, Margherita, Terpos, Evangelos, Ntanasis-Stathopoulos, Ioannis, Agarwal, Mahesh, Bear, Jenifer, Burns, Robert, Hu, Xintao, Korompoki, Eleni, Donohue, Duncan, Venzon, David J, Dimopoulos, Meletios-Athanasios, Pavlakis, George N, Felber, Barbara K

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Heterodimeric IL-15 in Cancer Immunotherapy von Bergamaschi, Cristina, Stravokefalou, Vasiliki, Stellas, Dimitris, Karaliota, Sevasti, Felber, Barbara K, Pavlakis, George N

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HIV-1 conserved elements p24CE DNA vaccine induces humoral immune responses with broad epitope recognition in macaques von Kulkarni, Viraj, Valentin, Antonio, Rosati, Margherita, Rolland, Morgane, Mullins, James I, Pavlakis, George N, Felber, Barbara K

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Towards a European strategy to address the COVID-19 pandemic von Priesemann, Viola, Balling, Rudi, Bauer, Simon, Beutels, Philippe, Valdez, André Calero, Cuschieri, Sarah, Czypionka, Thomas, Dumpis, Uga, Glaab, Enrico, Grill, Eva, Hotulainen, Pirta, Iftekhar, Emil N, Krutzinna, Jenny, Lionis, Christos, Machado, Helena, Martins, Carlos, McKee, Martin, Pavlakis, George N, Perc, Matjaž, Petelos, Elena, Pickersgill, Martyn, Prainsack, Barbara, Rocklöv, Joacim, Schernhammer, Eva, Szczurek, Ewa, Tsiodras, Sotirios, Van Gucht, Steven, Willeit, Peter

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A human immune data-informed vaccine concept elicits strong and broad T-cell specificities associated with HIV-1 control in mice and macaques von Mothe, Beatriz, Hu, Xintao, Llano, Anuska, Rosati, Margherita, Olvera, Alex, Kulkarni, Viraj, Valentin, Antonio, Alicea, Candido, Pilkington, Guy R, Sardesai, Niranjan Y, Rocafort, Muntsa, Crespo, Manel, Carrillo, Jorge, Marco, Andrés, Mullins, James I, Dorrell, Lucy, Hanke, Tomáš, Clotet, Bonaventura, Pavlakis, George N, Felber, Barbara K, Brander, Christian

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Balance of cellular and humoral immunity determines the level of protection by HIV vaccines in rhesus macaque models of HIV infection von Fouts, Timothy R., Bagley, Kenneth, Prado, Ilia J., Bobb, Kathryn L., Schwartz, Jennifer A., Xu, Rong, Zagursky, Robert J., Egan, Michael A., Eldridge, John H., LaBranche, Celia C., Montefiori, David C., Le Buanec, Hélène, Zagury, Daniel, Pal, Ranajit, Pavlakis, George N., Felber, Barbara K., Franchini, Genoveffa, Gordon, Shari, Vaccari, Monica, Lewis, George K., DeVico, Anthony L., Gallo, Robert C.

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Scalable, cGMP-compatible purification of extracellular vesicles carrying bioactive human heterodimeric IL-15/lactadherin complexes von Watson, Dionysios C., Yung, Bryant C., Bergamaschi, Cristina, Chowdhury, Bhabadeb, Bear, Jenifer, Stellas, Dimitris, Morales-Kastresana, Aizea, Jones, Jennifer C., Felber, Barbara K., Chen, Xiaoyuan, Pavlakis, George N.

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Tumor eradication by hetIL-15 locoregional therapy correlates with an induced intratumoral CD103intCD11b+ dendritic cell population von Stellas, Dimitris, Karaliota, Sevasti, Stravokefalou, Vasiliki, Angel, Matthew, Nagy, Bethany A., Goldfarbmuren, Katherine C., Bergamaschi, Cristina, Felber, Barbara K., Pavlakis, George N.

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Heterodimeric IL-15 (hetIL-15) reduces circulating tumor cells and metastasis formation improving chemotherapy and surgery in 4T1 mouse model of TNBC von Stravokefalou, Vasiliki, Stellas, Dimitris, Karaliota, Sevasti, Nagy, Bethany A, Valentin, Antonio, Bergamaschi, Cristina, Dimas, Konstantinos, Pavlakis, George N

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