Both positional and chemical variables control in vitro proteolytic cleavage of a presenilin ortholog von Naing, Swe-Htet, Kalyoncu, Sibel, Smalley, David M., Kim, Hyojung, Tao, Xingjian, George, Josh B., Jonke, Alex P., Oliver, Ryan C., Urban, Volker S., Torres, Matthew P., Lieberman, Raquel L.

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Individual Responses to Heat Stress: Implications for Hyperthermia and Physical Work Capacity von Foster, Josh, Hodder, Simon G., Lloyd, Alex B., Havenith, George

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Multisite Investigation of Outcomes With Implementation of CYP2C19 Genotype-Guided Antiplatelet Therapy After Percutaneous Coronary Intervention von Cavallari, Larisa H., Lee, Craig R., Beitelshees, Amber L., Cooper-DeHoff, Rhonda M., Duarte, Julio D., Voora, Deepak, Kimmel, Stephen E., McDonough, Caitrin W., Gong, Yan, Dave, Chintan V., Pratt, Victoria M., Alestock, Tameka D., Anderson, R. David, Alsip, Jorge, Ardati, Amer K., Brott, Brigitta C., Brown, Lawrence, Chumnumwat, Supatat, Clare-Salzler, Michael J., Coons, James C., Denny, Joshua C., Dillon, Chrisly, Elsey, Amanda R., Hamadeh, Issam S., Harada, Shuko, Hillegass, William B., Hines, Lindsay, Horenstein, Richard B., Howell, Lucius A., Jeng, Linda J.B., Kelemen, Mark D., Lee, Yee Ming, Magvanjav, Oyunbileg, Montasser, May, Nelson, David R., Nutescu, Edith A., Nwaba, Devon C., Pakyz, Ruth E., Palmer, Kathleen, Peterson, Josh F., Pollin, Toni I., Quinn, Alison H., Robinson, Shawn W., Schub, Jamie, Skaar, Todd C., Smith, D. Max, Sriramoju, Vindhya B., Starostik, Petr, Stys, Tomasz P., Stevenson, James M., Varunok, Nicholas, Vesely, Mark R., Wake, Dyson T., Weck, Karen E., Weitzel, Kristin W., Wilke, Russell A., Willig, James, Zhao, Richard Y., Kreutz, Rolf P., Stouffer, George A., Empey, Philip E., Limdi, Nita A., Shuldiner, Alan R., Winterstein, Almut G., Johnson, Julie A.

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Comparison of early versus delayed strategies for repair of congenital diaphragmatic hernia on extracorporeal membrane oxygenation von Robertson, Jason O., Criss, Cory N., Hsieh, Lily B., Matsuko, Niki, Gish, Josh S., Mon, Rodrigo A., Johnson, Kevin N., Hirschl, Ronald B., Mychaliska, George B., Gadepalli, Samir K.

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Turtles and Tortoises Are in Trouble von Stanford, Craig B., Iverson, John B., Rhodin, Anders G.J., Paul van Dijk, Peter, Mittermeier, Russell A., Kuchling, Gerald, Berry, Kristin H., Bertolero, Alberto, Bjorndal, Karen A., Blanck, Torsten E.G., Buhlmann, Kurt A., Burke, Russell L., Congdon, Justin D., Diagne, Tomas, Edwards, Taylor, Eisemberg, Carla C., Ennen, Josh R., Forero-Medina, Germán, Frankel, Matt, Fritz, Uwe, Gallego-García, Natalia, Georges, Arthur, Gibbons, J. Whitfield, Gong, Shiping, Goode, Eric V., Shi, Haitao T., Hoang, Ha, Hofmeyr, Margaretha D., Horne, Brian D., Hudson, Rick, Juvik, James O., Kiester, Ross A., Koval, Patricia, Le, Minh, Lindeman, Peter V., Lovich, Jeffrey E., Luiselli, Luca, McCormack, Timothy E.M., Meyer, George A., Páez, Vivian P., Platt, Kalyar, Platt, Steven G., Pritchard, Peter C.H., Quinn, Hugh R., Roosenburg, Willem M., Seminoff, Jeffrey A., Shaffer, H. Bradley, Spencer, Ricky, Van Dyke, James U., Vogt, Richard C., Walde, Andrew D.

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Sustainable solutions to mitigate occupational heat strain - an umbrella review of physiological effects and global health perspectives von Morris, Nathan B., Jay, Ollie, Flouris, Andreas D., Casanueva, Ana, Gao, Chuansi, Foster, Josh, Havenith, George, Nybo, Lars

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Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders von Võsa, Urmo, Stathopoulou, Maria G., de Vries, Paul S., Tanaka, Toshiko, Wu, Ying, Karlsson, Robert, Pool, René, Kemp, John P., Verweij, Niek, Smith, Albert V., Huq, Mahmudul, Deelen, Joris, Alizadeh, Behrooz Z., van der Harst, Pim, Navis, Gerjan, Snieder, Harold, Chasman, Daniel I., Meigs, James, Ligthart, Symen, Bis, Josh, Gross, Myron, Koenig, Wolfgang, Uher, Rudolf, Ward-Caviness, Cavin, Boerwinkle, Eric, Stacey, David, Eriksson, Johan, Lahti, Jari, Schraut, Katharina E., Suktitipat, Bhoom, Nutile, Teresa, Schork, Nicholas, Thiering, Elisabeth, Mahajan, Anubha, Aslibekyan, Stella, Yengo, Loïc, Rajan, Kumar B., Timpson, Nicholas, Huang, Hongyan, Uh, Hae-Won, Yanek, Lisa R., Verbanck, Marie, Magnusson, Patrik K.E., Ballantyne, Christie M., Montgomery, Grant W., Rueedi, Rico, Steri, Maristella, Stott, David J., Felix, Stephan B., Kraft, Peter, Seppälä, Ilkka, Williams, Stephen R., Moed, Matthijs, Langenberg, Claudia, Räikkönen, Katri, Sale, Michele M., Chen, Yii-Der I., James, Alan L., Soranzo, Nicole, Berenson, Gerald S., Liewald, David, Beilby, John, Ryan, Kathleen A., Balkau, Beverly, Paternoster, Lavinia, Kähönen, Mika, Sattar, Naveed, van Heemst, Diana, Gambaro, Giovanni, Ferrucci, Luigi, Karlsson, Magnus, Lind, Lars, Mori, Trevor A., Buckley, Brendan M., de Craen, Anton J.M., Scott, Rodney J., Strachan, David P., Jarvelin, Marjo-Riitta, Jukema, J. Wouter, Hamsten, Anders, Gudnason, Vilmundur, Qi, Lu, März, Winfried, Penninx, Brenda W.J.H., Worrall, Bradford B., Gibson, Greg, Oldehinkel, Albertine J., Murray, Sarah S., Pramstaller, Peter P., Deary, Ian J., Desch, Karl C., Hayward, Caroline, Arnett, Donna K., Jess, Tine, Psaty, Bruce M., Tracy, Russell P., Nolte, Ilja M., Visvikis-Siest, Sophie, Franke, Lude, Franco, Oscar H.

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GWAS of thyroid stimulating hormone highlights pleiotropic effects and inverse association with thyroid cancer von Zhou, Wei, Brumpton, Ben, Kabil, Omer, Gudmundsson, Julius, Thorleifsson, Gudmar, Weinstock, Josh, Zawistowski, Matthew, Nielsen, Jonas B., Chaker, Layal, Medici, Marco, Teumer, Alexander, Naitza, Silvia, Sanna, Serena, Schultheiss, Ulla T., Cappola, Anne, Karjalainen, Juha, Kurki, Mitja, Oneka, Morgan, Taylor, Peter, Fritsche, Lars G., Graham, Sarah E., Wolford, Brooke N., Overton, William, Rasheed, Humaira, Haug, Eirin B., Gabrielsen, Maiken E., Skogholt, Anne Heidi, Surakka, Ida, Davey Smith, George, Pandit, Anita, Roychowdhury, Tanmoy, Hornsby, Whitney E., Jonasson, Jon G., Senter, Leigha, Liyanarachchi, Sandya, Ringel, Matthew D., Xu, Li, Kiemeney, Lambertus A., He, Huiling, Netea-Maier, Romana T., Mayordomo, Jose I., Plantinga, Theo S., Hrafnkelsson, Jon, Hjartarson, Hannes, Sturgis, Erich M., Palotie, Aarno, Daly, Mark, Citterio, Cintia E., Arvan, Peter, Brummett, Chad M., Boehnke, Michael, de la Chapelle, Albert, Stefansson, Kari, Hveem, Kristian, Willer, Cristen J., Åsvold, Bjørn Olav

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Multisite Investigation of Strategies for the Implementation of CYP2C19 Genotype‐Guided Antiplatelet Therapy von Empey, Philip E., Stevenson, James M., Tuteja, Sony, Weitzel, Kristin W., Angiolillo, Dominick J., Beitelshees, Amber L., Coons, James C., Duarte, Julio D., Franchi, Francesco, Jeng, Linda J.B., Johnson, Julie A., Kreutz, Rolf P., Limdi, Nita A., Maloney, Kristin A., Owusu Obeng, Aniwaa, Peterson, Josh F., Petry, Natasha, Pratt, Victoria M., Rollini, Fabiana, Scott, Stuart A., Skaar, Todd C., Vesely, Mark R., Stouffer, George A., Wilke, Russell A., Cavallari, Larisa H., Lee, Craig R.

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Chronic Noncommunicable Diseases in 6 Low- and Middle-Income Countries: Findings From Wave 1 of the World Health Organization's Study on Global Ageing and Adult Health (SAGE) von Arokiasamy, Perianayagam, Uttamacharya, Kowal, Paul, Capistrant, Benjamin D, Gildner, Theresa E, Thiele, Elizabeth, Biritwum, Richard B, Yawson, Alfred E, Mensah, George, Maximova, Tamara, Wu, Fan, Guo, Yanfei, Zheng, Yang, Kalula, Sebastiana Zimba, Salinas Rodríguez, Aarón, Manrique Espinoza, Betty, Liebert, Melissa A, Eick, Geeta, Sterner, Kirstin N, Barrett, Tyler M, Duedu, Kwabena, Gonzales, Ernest, Ng, Nawi, Negin, Joel, Jiang, Yong, Byles, Julie, Madurai, Savathree Lorna, Minicuci, Nadia, Snodgrass, J Josh, Naidoo, Nirmala, Chatterji, Somnath

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Biomarkers of coagulation, endothelial, platelet function, and fibrinolysis in patients with COVID-19: a prospective study von S.B., Manoj Job, Chacko, Binila, Selvarajan, Sushil, Peter, John Victor, Geevar, Tulasi, Dave, Rutvi Gautam, Georgy, Josh Thomas, Zachariah, Anand, George, Tina, Sathyendra, Sowmya, Hansdak, Samuel George, Krishnaswami, Rajiv Karthik, Thangakunam, Balamugesh, Gupta, Richa, Karuppusami, Reka, Nair, Sukesh Chandran, Srivastava, Alok

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LSST: From Science Drivers to Reference Design and Anticipated Data Products von Tyson, J. Anthony, Acosta, Emily, AlSayyad, Yusra, Anderson, Scott F., Antilogus, Pierre, Araujo, Constanza, Armstrong, Robert, Aubourg, Éric, Bauer, Amanda E., Baumont, Sylvain, Bechtol, Ellen, Bechtol, Keith, Becla, Jacek, Bellavia, Steve, Blanc, Guillaume, Blazek, Jonathan, Bogart, Joanne, Bond, Tim W., Bosch, James F., Brandt, William Nielsen, Calabrese, Daniel, Carlin, Jeffrey L., Chiang, James, Chirino, Carol, Chow, Derek, Ciardi, David R., Claver, Charles F., Cockrum, Joseph J., Covey, Kevin R., Cui, Wei, Daly, Philip N., Daubard, Guillaume, Daues, Greg, Dubois-Felsmann, Gregory P., Eifler, Tim, Fisher-Levine, Merlin, Gilmore, D. Kirk, Goodenow, Iain, Guy, Leanne P., Hascall, Patrick A., Hernandez, Fabio, Hoblitt, Joshua, Hodgson, John A., Hogan, Craig, Huffer, Michael E., Jacoby, Suzanne H., Jain, Bhuvnesh, Jammes, Fabrice, Jernigan, Garrett, Johnson, Margaret W. G., Kessler, Richard, Kirkby, David, Krughoff, K. Simon, Kubánek, Petr, Kulkarni, Shri, Lambert, Ron, Levine, Deborah, Lim, Kian-Tat, Lopez, Margaux, Lupton, Robert H., Lust, Nate B., MacArthur, Lauren A., Markiewicz, Thomas W., Marshall, Philip J., Meyers, Joshua, Miller, Michelle, Mueller, Fritz, Muller, Gary P., Newbry, Scott P., Nomerotski, Andrei, Oliver, John, Ortiz, Sandra, Owen, Russell E., Pain, Reynald, Pierfederici, Francesco, Plate, Stephen, Plutchak, Joel P., Rajagopal, Jayadev, Rasmussen, Andrew P., Reil, Kevin A., Reiss, David J., Ridgway, Stephen T., Ritz, Steve, Roodman, Aaron, Schindler, Rafe H., Schmidt, Samuel, Selvy, Brian, Seppala, Lynn G., Serio, Andrew, Serrano, Eduardo, Silvestri, Nicole, Street, Rachel A., Takacs, Peter, Tice, Jeffrey, Vetter, Kurt, Virieux, Francoise, Walsh, Brian, Wang, Daniel L., Wittman, David, Yoachim, Peter

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Reliability and validity of methods in the assessment of cold-induced shivering thermogenesis von Arnold, Josh T., Hemsley, Zach, Hodder, Simon G., Havenith, George, Lloyd, Alex B.

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Genome remodelling in a basal-like breast cancer metastasis and xenograft von Wilson, Richard K, Ding, Li, Ellis, Matthew J, Li, Shunqiang, Larson, David E, Chen, Ken, Wallis, John W, Harris, Christopher C, McLellan, Michael D, Fulton, Robert S, Fulton, Lucinda L, Abbott, Rachel M, Hoog, Jeremy, Dooling, David J, Koboldt, Daniel C, Schmidt, Heather, Kalicki, Joelle, Zhang, Qunyuan, Chen, Lei, Lin, Ling, Wendl, Michael C, McMichael, Joshua F, Magrini, Vincent J, Cook, Lisa, McGrath, Sean D, Vickery, Tammi L, Appelbaum, Elizabeth, DeSchryver, Katherine, Davies, Sherri, Guintoli, Therese, Lin, Li, Crowder, Robert, Tao, Yu, Snider, Jacqueline E, Smith, Scott M, Dukes, Adam F, Sanderson, Gabriel E, Pohl, Craig S, Delehaunty, Kim D, Fronick, Catrina C, Pape, Kimberley A, Reed, Jerry S, Robinson, Jody S, Hodges, Jennifer S, Schierding, William, Dees, Nathan D, Shen, Dong, Locke, Devin P, Wiechert, Madeline E, Eldred, James M, Peck, Josh B, Oberkfell, Benjamin J, Lolofie, Justin T, Du, Feiyu, Hawkins, Amy E, O’Laughlin, Michelle D, Bernard, Kelly E, Cunningham, Mark, Elliott, Glendoria, Mason, Mark D, Thompson Jr, Dominic M, Ivanovich, Jennifer L, Goodfellow, Paul J, Perou, Charles M, Weinstock, George M, Aft, Rebecca, Watson, Mark, Ley, Timothy J, Mardis, Elaine R

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Fear Fosters Flight: A Mechanism for Fear Contagion When Perceiving Emotion Expressed by a Whole Body von de Gelder, Beatrice, Snyder, Josh, Greve, Doug, Gerard, George, Hadjikhani, Nouchine, Held, Richard M.

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Remdesivir for the treatment of patients in hospital with COVID-19 in Canada: a randomized controlled trial von Ali, Karim, Azher, Tanweer, Baqi, Mahin, Binnie, Alexandra, Borgia, Sergio, Carrier, François M, Cavayas, Yiorgos Alexandroa, Chagnon, Nicolas, Cheng, Matthew P, Conly, John, Costiniuk, Cecilia, Daley, Peter, Daneman, Nick, Douglas, Josh, Downey, Catarina, Duan, Erick, Duceppe, Emmanuelle, Durand, Madeleine, English, Shane, Farjou, George, Fera, Evradiki, Fontela, Patricia, Fowler, Rob, Fralick, Michael, Geagea, Anna, Grant, Jennifer, Harrison, Luke B, Havey, Thomas, Hoang, Holly, Kelly, Lauren E, Keynan, Yoav, Khwaja, Kosar, Klein, Gail, Klein, Marina, Kolan, Christophe, Kronfli, Nadine, Lamontagne, Francois, Lau, Rob, Lee, Todd C, Lee, Nelson, Lim, Rachel, Longo, Sarah, Lostun, Alexandra, MacIntyre, Erika, Malhamé, Isabelle, Mangof, Kathryn, McGuinty, Marlee, Mergler, Sonya, Munan, Matthew P, Murthy, Srinivas, O'Neil, Conar, Ovakim, Daniel, Papenburg, Jesse, Parhar, Ken, Parvathy, Seema Nair, Patel, Chandni, Perez-Patrigeon, Santiago, Pinto, Ruxandra, Rajakumaran, Subitha, Rishu, Asgar, Roba-Oshin, Malaika, Rushton, Moira, Saleem, Mariam, Salvadori, Marina, Scherr, Kim, Schwartz, Kevin, Semret, Makeda, Silverman, Michael, Singh, Ameeta, Sligl, Wendy, Smith, Stephanie, Somayaji, Ranjani, Tan, Darrell H S, Tobin, Siobhan, Todd, Meaghan, Tran, Tuong-Vi, Tremblay, Alain, Tsang, Jennifer, Turgeon, Alexis, Vakil, Erik, Weatherald, Jason, Yansouni, Cedric, Zarychanski, Ryan

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A phase I trial of pembrolizumab with hypofractionated radiotherapy in patients with metastatic solid tumours von Maity, Amit, Mick, Rosemarie, Huang, Alexander C., George, Sangeeth M., Farwell, Michael D., Lukens, John N., Berman, Abigail T., Mitchell, Tara C., Bauml, Josh, Schuchter, Lynn M., O’Hara, Mark, Lin, Lilie L., Demichele, Angela, Christodouleas, John P., Haas, Naomi B., Patsch, Dana M., Hahn, Stephen M., Minn, Andy J., Wherry, E. John, Vonderheide, Robert H.

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An examination of five theoretical foundations associated with localized thermosensory testing von Temel, Mevra, Johnson, Andrew A., Havenith, George, Arnold, Josh T., West, Anna M., Lloyd, Alex B.

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CTNNA3 and SEMA3D : Promising loci for asthma exacerbation identified through multiple genome-wide association studies von McGeachie, Michael J., PhD, Wu, Ann C., MD, Tse, Sze Man, MD, Clemmer, George L., MS, Sordillo, Joanne, ScD, Himes, Blanca E., PhD, Lasky-Su, Jessica, PhD, Chase, Robert P., MS, Martinez, Fernando D., MD, Weeke, Peter, MD, Shaffer, Christian M., BS, Xu, Hua, PhD, Denny, Josh C., MD, Roden, Dan M., MD, Panettieri, Reynold A., MD, Raby, Benjamin A., MD, Weiss, Scott T., MD, Tantisira, Kelan G., MD

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From anecdotes to quantification: advances in characterizing volcanic eruption impacts on the built environment von Deligne, Natalia Irma, Jenkins, Susanna F., Meredith, Elinor S., Williams, George T., Leonard, Graham S., Stewart, Carol, Wilson, Thomas M., Biass, Sébastien, Blake, Daniel M., Blong, Russell J., Bonadonna, Costanza, Calderon B., Rodrigo, Hayes, Josh L., Johnston, David M., Kennedy, Ben M., Magill, Christina R., Spence, Robin, Wallace, Kristi L., Wardman, John, Weir, Alana M., Wilson, Grant, Zuccaro, Giulio

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