Alzheimer's disease hypothesis and related therapies von Du, Xiaoguang, Wang, Xinyi, Geng, Meiyu

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Targeting ERK, an Achilles' Heel of the MAPK pathway, in cancer therapy von Liu, Feifei, Yang, Xiaotong, Geng, Meiyu, Huang, Min

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Molecularly targeted cancer therapy: some lessons from the past decade von Huang, Min, Shen, Aijun, Ding, Jian, Geng, Meiyu

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Sodium oligomannate therapeutically remodels gut microbiota and suppresses gut bacterial amino acids-shaped neuroinflammation to inhibit Alzheimer’s disease progression von Wang, Xinyi, Sun, Guangqiang, Feng, Teng, Zhang, Jing, Huang, Xun, Wang, Tao, Xie, Zuoquan, Chu, Xingkun, Yang, Jun, Wang, Huan, Chang, Shuaishuai, Gong, Yanxue, Ruan, Lingfei, Zhang, Guanqun, Yan, Siyuan, Lian, Wen, Du, Chen, Yang, Dabing, Zhang, Qingli, Lin, Feifei, Liu, Jia, Zhang, Haiyan, Ge, Changrong, Xiao, Shifu, Ding, Jian, Geng, Meiyu

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Aspirin Inhibits Cancer Metastasis and Angiogenesis via Targeting Heparanase von Dai, Xiaoyang, Yan, Juan, Fu, Xuhong, Pan, Qiuming, Sun, Danni, Xu, Yuan, Wang, Jiang, Nie, Litong, Tong, Linjiang, Shen, Aijun, Zheng, Mingyue, Huang, Min, Tan, Minjia, Liu, Hong, Huang, Xun, Ding, Jian, Geng, Meiyu

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Chemotherapy-induced intestinal inflammatory responses are mediated by exosome secretion of double-strand DNA via AIM2 inflammasome activation von Lian, Qiaoshi, Xu, Jun, Yan, Shanshan, Huang, Min, Ding, Honghua, Sun, Xiaoyu, Bi, Aiwei, Ding, Jian, Sun, Bing, Geng, Meiyu

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Targeting Epigenetic Crosstalk as a Therapeutic Strategy for EZH2-Aberrant Solid Tumors von Huang, Xun, Yan, Juan, Zhang, Min, Wang, Yafang, Chen, Yi, Fu, Xuhong, Wei, Rongrui, Zheng, Xing-ling, Liu, Zhiwei, Zhang, Xiong, Yang, Hong, Hao, Bingbing, Shen, Yan-yan, Su, Yi, Cong, Xiaoji, Huang, Min, Tan, Minjia, Ding, Jian, Geng, Meiyu

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Discovery of Novel Janus Kinase (JAK) and Histone Deacetylase (HDAC) Dual Inhibitors for the Treatment of Hematological Malignancies von Liang, Xuewu, Zang, Jie, Li, Xiaoyang, Tang, Shuai, Huang, Min, Geng, Meiyu, Chou, C. James, Li, Chunpu, Cao, Yichun, Xu, Wenfang, Liu, Hong, Zhang, Yingjie

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p53 β-hydroxybutyrylation attenuates p53 activity von Liu, Kun, Li, Fangzhou, Sun, Qianqian, Lin, Ning, Han, Haichao, You, Kaiqiang, Tian, Feng, Mao, Zebin, Li, Tingting, Tong, Tanjun, Geng, Meiyu, Zhao, Yingming, Gu, Wei, Zhao, Wenhui

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Identification of metabolic vulnerabilities of receptor tyrosine kinases-driven cancer von Jin, Nan, Bi, Aiwei, Lan, Xiaojing, Xu, Jun, Wang, Xiaomin, Liu, Yingluo, Wang, Ting, Tang, Shuai, Zeng, Hanlin, Chen, Ziqi, Tan, Minjia, Ai, Jing, Xie, Hua, Zhang, Tao, Liu, Dandan, Huang, Ruimin, Song, Yue, Leung, Elaine Lai-Han, Yao, Xiaojun, Ding, Jian, Geng, Meiyu, Lin, Shu-Hai, Huang, Min

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Chronic Kidney Disease and Cognitive Impairment: The Kidney-Brain Axis von Xie, Zuoquan, Tong, Siyu, Chu, Xingkun, Feng, Teng, Geng, Meiyu

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Development of a novel lactate dehydrogenase A inhibitor with potent antitumor activity and immune activation von Du, Mengyan, Yu, Ting, Zhan, Qinjinge, Li, Han, Zou, Yiping, Geng, Meiyu, Meng, Tao, Xie, Zuoquan

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Preclinical Evaluation of SCC244 (Glumetinib), a Novel, Potent, and Highly Selective Inhibitor of c-Met in MET-dependent Cancer Models von Ai, Jing, Chen, Yi, Peng, Xia, Ji, Yinchun, Xi, Yong, Shen, Yanyan, Yang, Xinying, Su, Yi, Sun, Yiming, Gao, Yinglei, Ma, Yuchi, Xiong, Bing, Shen, Jingkang, Ding, Jian, Geng, Meiyu

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Discovery of Potent Irreversible Pan-Fibroblast Growth Factor Receptor (FGFR) Inhibitors von Wang, Yuming, Li, Lijun, Fan, Jun, Dai, Yang, Jiang, Alan, Geng, Meiyu, Ai, Jing, Duan, Wenhu

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GV-971 prevents severe acute pancreatitis by remodeling the microbiota-metabolic-immune axis von Chen, Xi, Chen, Xin, Yan, Ding, Zhang, Na, Fu, Wen, Wu, Meixuan, Ge, Feifei, Wang, Jiangtuan, Li, Xiaofen, Geng, Meiyu, Wang, Jinheng, Tang, Daolin, Liu, Jinbao

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Phosphoglycerate mutase 1 regulates dNTP pool and promotes homologous recombination repair in cancer cells von Qu, Jia, Sun, Wenyi, Zhong, Jie, Lv, Hao, Zhu, Mingrui, Xu, Jun, Jin, Nan, Xie, Zuoquan, Tan, Minjia, Lin, Shu-Hai, Geng, Meiyu, Ding, Jian, Huang, Min

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Discovery of a novel third-generation EGFR inhibitor and identification of a potential combination strategy to overcome resistance von Zhang, Tao, Qu, Rong, Chan, Shingpan, Lai, Mengzhen, Tong, Linjiang, Feng, Fang, Chen, Hongyu, Song, Tingting, Song, Peiran, Bai, Gang, Liu, Yingqiang, Wang, Yanan, Li, Yan, Su, Yi, Shen, Yanyan, Sun, Yiming, Chen, Yi, Geng, Meiyu, Ding, Ke, Ding, Jian, Xie, Hua

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LS‐106, a novel EGFR inhibitor targeting C797S, exhibits antitumor activities both in vitro and in vivo von Liu, Yingqiang, Lai, Mengzhen, Li, Shan, Wang, Yanan, Feng, Fang, Zhang, Tao, Tong, Linjiang, Zhang, Mengge, Chen, Hao, Chen, Yi, Song, Peiran, Li, Yan, Bai, Gang, Ning, Yi, Tang, Haotian, Fang, Yan, Chen, Yi, Lu, Xiaoyun, Geng, Meiyu, Ding, Ke, Yu, Ker, Xie, Hua, Ding, Jian

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c-Myc Alteration Determines the Therapeutic Response to FGFR Inhibitors von Liu, Hongyan, Ai, Jing, Shen, Aijun, Chen, Yi, Wang, Xinyi, Peng, Xia, Chen, Hui, Shen, Yanyan, Huang, Min, Ding, Jian, Geng, Meiyu

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Curcumin induces cell death and restores tamoxifen sensitivity in the antiestrogen-resistant breast cancer cell lines MCF-7/LCC2 and MCF-7/LCC9 von Jiang, Min, Huang, Ou, Zhang, Xi, Xie, Zuoquan, Shen, Aijun, Liu, Hongchun, Geng, Meiyu, Shen, Kunwei

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