Assessment of specificity of eight chemical inhibitors using cDNA-expressed cytochromes P450 von Sai, Y., Dai, R., Yang, T. J., Krausz, K. W., Gonzalez, F. J., Gelboin, H. V., Shou, M.

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Activation of CYP3A4: Evidence for the Simultaneous Binding of Two Substrates in a Cytochrome P450 Active Site von Shou, M, Grogan, J, Mancewicz, J. A, Krausz, K. W, Gonzalez, F. J, Gelboin, H. V, Korzekwa, K. R

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Hydroxylation of warfarin by human cDNA-expressed cytochrome P-450: a role for P-4502C9 in the etiology of (S)-warfarin-drug interactions von Rettie, Allan E, Korzekwa, Kenneth R, Kunze, Kent L, Lawrence, Ross F, Eddy, A Craig, Aoyama, Toshifumi, Gelboin, Harry V, Gonzalez, Frank J, Trager, William F

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Role of Human Cytochromes P450 in the Metabolic Activation of Chemical Carcinogens and Toxins von Gonzalez, Frank J., Gelboin, Harry V.

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Stereoselective Epoxidation and Hydration at the K-Region of Polycyclic Aromatic Hydrocarbons by cDNA-expressed Cytochromes P450 1A1, 1A2, and Epoxide Hydrolase von Shou, M, Gonzalez, F. J, Gelboin, H. V

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Role of human hepatic cytochrome P450 1A2 and 3A4 in the metabolic activation of estrone von SHOU, M, KORZEKWA, K. R, BROOKS, E. N, KRAUSZ, K. W, GONZALEZ, F. J, GELBOIN, H. V

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Cytochrome P-450 hPCN3, a novel cytochrome P-450 IIIA gene product that is differentially expressed in adult human liver. cDNA and deduced amino acid sequence and distinct specific... von AOYAMA, T, YAMAMO, S, GONZALEZ, F. J, WAXMAN, D. J, LAPENSON, D. P, MEYER, U. A, FISCHER, V, TYNDALE, R, INABA, T, KALOW, W, GELBOIN, H. V

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Induction of Rat Hepatic N-Nitrosodimethylamine Demethylase by Acetone Is Due to Protein Stabilization von Song, B J, Veech, R L, Park, S S, Gelboin, H V, Gonzalez, F J

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Five of 12 Forms of Vaccinia Virus-Expressed Human Hepatic Cytochrome P450 Metabolically Activate Aflatoxin B1 von Aoyama, Toshifumi, Yamano, Shigeru, Guzelian, Philip S., Gelboin, Harry V., Gonzalez, Frank J.

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Benzo[alpha]pyrene metabolism, activation and carcinogenesis: role and regulation of mixed-function oxidases and related enzymes von Gelboin, H V

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Complementary DNA and protein sequences of ethanol-inducible rat and human cytochrome P-450s. Transcriptional and post-transcriptional regulation of the rat enzyme von Song, B J, Gelboin, H V, Park, S S, Yang, C S, Gonzalez, F J

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CYP2C subfamily, primarily CYP2C9, catalyses the enantioselective demethylation of the endocrine disruptor pesticide methoxychlor in human liver microsomes: use of inhibitory monoc... von Hu, Y., Krausz, K., Gelboin, H. V., Kupfer, D.

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A tobacco smoke-derived nitrosamine, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, is activated by multiple human cytochrome P450s including the polymorphic human cytochrome P450... von CRESPI, C. L, PENMAN, B. W, GELBOIN, H. V, GONZALEZ, F. J

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Metabolic activation of the potent carcinogen dibenzo[a, l]pyrene by human recombinant cytochromes P450, lung and liver microsomes von Shou, Magang, Krausz, Kristopher W., Gonzalez, Frank J., Gelboin, Harry V.

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Use of inhibitory monoclonal antibodies to assess the contribution of cytochromes P450 to human drug metabolism von Shou, Magang, Lu, Tin, Krausz, Kristopher W., Sai, Yang, Yang, Tianjian, Korzekwa, Kenneth R., Gonzalez, Frank J., Gelboin, Harry V.

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Role of cDNA-Expressed Human Cytochromes P450 in the Metabolism of Diazepam von Yang, Tian J, Shou, Magang, Korzekwa, Kenneth R, Gonzalez, Frank J, Gelboin, Harry V, Yang, Shen K

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Cytochromes P450 2A6, 2E1, and 3A and production of protein-aldehyde adducts in the liver of patients with alcoholic and non-alcoholic liver diseases von Niemelä, Onni, Parkkila, Seppo, Juvonen, Risto O, Viitala, Katja, Gelboin, Harry V, Pasanen, Markku

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Human Cytochromes P450: Evolution and cDNA-Directed Expression von Gonzalez, Frank J., Gelboin, Harry V.

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Quantification of CYP2B7, CYP4B1, and CYPOR messenger RNAs in normal human lung and lung tumors von CZERWINSKI, M, MCLEMORE, T. L, GELBOIN, H. V, GONZALEZ, F. J

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Targeted disruption of the microsomal epoxide hydrolase gene. Microsomal epoxide hydrolase is required for the carcinogenic activity of 7,12-dimethylbenz[a]anthracene von Miyata, M, Kudo, G, Lee, Y H, Yang, T J, Gelboin, H V, Fernandez-Salguero, P, Kimura, S, Gonzalez, F J

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