20 Direct Targeting of Pro-apoptotic BAX for Cancer Therapy von Reyna, D, Bellairs, J, Walensky, L, Gavathiotis, E

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BCL-2 Family Proteins: Methods and Protocols von Gavathiotis, Evripidis

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Cooperativity in Drug−DNA Recognition:  A Molecular Dynamics Study von Harris, Sarah A, Gavathiotis, Evripidis, Searle, Mark S, Orozco, Modesto, Laughton, Charles A

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Sequence-dependent variation in DNA minor groove width dictates orientational preference of Hoechst 33258 in A-tract recognition: solution NMR structure of the 2:1 complex with d(C... von Gavathiotis, E.

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Chaperone-mediated autophagy sustains hematopoietic stem cell function von Dong, S, Wang, Q, Kao, YR, Diaz, A, Tasset, I, Kaushik, S, Thiruthuvanathan, V, Zintiridou, A, Nieves, E, Dzieciatkowska, M, Reisz, JA, Gavathiotis, E, D’Alessandro, A, Will, B, Cuervo, AM

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Drug Recognition and Stabilisation of the Parallel-stranded DNA Quadruplex d(TTAGGGT) 4 Containing the Human Telomeric Repeat von Gavathiotis, Evripidis, Heald, Robert A., Stevens, Malcolm F.G., Searle, Mark S.

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A Mechanism for Death Receptor Discrimination by Death Adaptors von Sandu, Cristinel, Gavathiotis, Evripidis, Huang, Ted, Wegorzewska, Iga, Werner, Milton H.

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Sequence-dependent variation in DNA minor groove width dictates orientational preference of Hoechst 33258 in A-tract recognition: solution NMR structure of the 2:1 complex with d(C... von Gavathiotis, E, Sharman, G J, Searle, M S

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Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018 von Galluzzi, L, Vitale, I, Aaronson, SA, Abrams, JM, Agostinis, P, Altucci, L, Amelio, I, Antonov, AV, Arama, E, Barlev, NA, Bertrand, MJM, Borner, C, Boya, P, Brenner, C, Campanella, M, Cecconi, F, Chandel, NS, Chipuk, JE, Cidlowski, JA, Ciechanover, A, Cohen, GM, Czabotar, PE, Dawson, TM, Dawson, VL, De Maria, R, Deshmukh, M, Di Virgilio, F, Dixit, VM, Dixon, SJ, El-Deiry, WS, Elrod, JW, Fulda, S, Garg, AD, Garrido, C, Gavathiotis, E, Golstein, P, Gottlieb, E, Green, DR, Greene, LA, Gronemeyer, H, Hajnoczky, G, Hardwick, JM, Harris, IS, Ichijo, H, Joseph, B, Juin, PP, Kaiser, WJ, Kepp, O, Kimchi, A, Knight, RA, Lee, SW, Lemasters, JJ, Levine, B, Lipton, SA, Lockshin, RA, López-Otín, C, Lowe, SW, Luedde, T, MacFarlane, M, Malorni, W, Manic, G, Martinou, J-C, Mehlen, P, Melino, S, Miao, EA, Moll, UM, Muñoz-Pinedo, C, Oberst, A, Oren, M, Overholtzer, M, Pagano, M, Panaretakis, T, Pasparakis, M, Penninger, JM, Pereira, DM, Peter, ME, Piacentini, M, Pinton, P, Puthalakath, H, Rabinovich, GA, Rizzuto, R, Rubinsztein, DC, Sayan, E, Shao, F, Shi, Y, Silke, J, Stockwell, BR, Strasser, A, Szabadkai, G, Tait, SWG, Vanden Berghe, T, Vander Heiden, MG, Wagner, EF, Walczak, H, Wang, Y, Wells, JA, Wood, W, Yuan, J, Zakeri, Z, Zitvogel, L

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Photocrosslinking Approach to Investigate Protein Interactions in the BCL-2 Family von Lin, Jialing, Johnson, Arthur E., Zhang, Zhi

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Liposomal Permeabilization Assay to Study the Functional Interactions of the BCL-2 Family von Reyna, Denis E., Gavathiotis, Evripidis

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Eltrombopag directly inhibits BAX and prevents cell death von Spitz, Adam Z., Zacharioudakis, Emmanouil, Reyna, Denis E., Garner, Thomas P., Gavathiotis, Evripidis

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Targeting Mitochondrial Structure Sensitizes Acute Myeloid Leukemia to Venetoclax Treatment von Chen, Xufeng, Glytsou, Christina, Zhou, Hua, Narang, Sonali, Reyna, Denis E, Lopez, Andrea, Sakellaropoulos, Theodore, Gong, Yixiao, Kloetgen, Andreas, Yap, Yoon Sing, Wang, Eric, Gavathiotis, Evripidis, Tsirigos, Aristotelis, Tibes, Raoul, Aifantis, Iannis

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Small-molecule allosteric inhibitors of BAX von Garner, Thomas P., Amgalan, Dulguun, Reyna, Denis E., Li, Sheng, Kitsis, Richard N., Gavathiotis, Evripidis

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Co-targeting of BAX and BCL-XL proteins broadly overcomes resistance to apoptosis in cancer von Lopez, Andrea, Reyna, Denis E., Gitego, Nadege, Kopp, Felix, Zhou, Hua, Miranda-Roman, Miguel A., Nordstrøm, Lars Ulrik, Narayanagari, Swathi-Rao, Chi, Ping, Vilar, Eduardo, Tsirigos, Aristotelis, Gavathiotis, Evripidis

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An interconnected hierarchical model of cell death regulation by the BCL-2 family von Chen, Hui-Chen, Kanai, Masayuki, Inoue-Yamauchi, Akane, Tu, Ho-Chou, Huang, Yafen, Ren, Decheng, Kim, Hyungjin, Takeda, Shugaku, Reyna, Denis E., Chan, Po M., Ganesan, Yogesh Tengarai, Liao, Chung-Ping, Gavathiotis, Evripidis, Hsieh, James J., Cheng, Emily H.

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BH3-Triggered Structural Reorganization Drives the Activation of Proapoptotic BAX von Gavathiotis, Evripidis, Reyna, Denis E., Davis, Marguerite L., Bird, Gregory H., Walensky, Loren D.

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Direct and selective small-molecule activation of proapoptotic BAX von Gavathiotis, Evripidis, Reyna, Denis E, Bellairs, Joseph A, Leshchiner, Elizaveta S, Walensky, Loren D

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ASXL1 mutations are associated with distinct epigenomic alterations that lead to sensitivity to venetoclax and azacytidine von Rahmani, Nora E., Ramachandra, Nandini, Sahu, Srabani, Gitego, Nadege, Lopez, Andrea, Pradhan, Kith, Bhagat, Tushar D., Gordon-Mitchell, Shanisha, Pena, Bianca Rivera, Kazemi, Mohammad, Rao, Keshav, Giricz, Orsi, Maqbool, Shahina Bano, Olea, Raul, Zhao, Yongmei, Zhang, Jinghang, Dolatshad, Hamid, Tittrea, Vickram, Tatwavedi, Dharamveer, Singh, Shalini, Lee, Juseong, Sun, Tianyu, Steidl, Ulrich, Shastri, Aditi, Inoue, Daichi, Abdel-Wahab, Omar, Pellagatti, Andrea, Gavathiotis, Evripidis, Boultwood, Jacqueline, Verma, Amit

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Bax regulates primary necrosis through mitochondrial dynamics von Whelan, Russell S, Konstantinidis, Klitos, Wei, An-Chi, Chen, Yun, Reyna, Denis E, Jha, Saurabh, Yang, Ying, Calvert, John W, Lindsten, Tullia, Thompson, Craig B, Crow, Michael T, Gavathiotis, Evripidis, Dorn, Gerald W. II, O'Rourke, Brian, Kitsis, Richard N

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