Genome-scale RNAi screen for host factors required for HIV replication von Zhou, Honglin, Xu, Min, Huang, Qian, Gates, Adam T, Zhang, Xiaohua D, Castle, John C, Stec, Erica, Ferrer, Marc, Strulovici, Berta, Hazuda, Daria J, Espeseth, Amy S

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MK-5172, a Selective Inhibitor of Hepatitis C Virus NS3/4a Protease with Broad Activity across Genotypes and Resistant Variants von SUMMA, Vincenzo, LUDMERER, Steven W, GATES, Adam T, GRAHAM, Donald J, HARPER, Steven, HAZUDA, Daria J, MCHALE, Carolyn, MONTEAGUDO, Edith, PUCCI, Vincenzo, ROWLEY, Michael, RUDD, Michael T, SORIANO, Aileen, MCCAULEY, John A, STAHLHUT, Mark W, VACCA, Joseph P, OLSEN, David B, LIVERTON, Nigel J, CARROLL, Steven S, FANDOZZI, Christine, BURLEIN, Christine, CLAUDIO, Giuliano, COLEMAN, Paul J, DIMUZIO, Jillian M, FERRARA, Marco, DI FILIPPO, Marcello

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A Limited Group of Class I Histone Deacetylases Acts To Repress Human Immunodeficiency Virus Type 1 Expression von KEEDY, Kara S, ARCHIN, Nancie M, GATES, Adam T, ESPESETH, Amy, HAZUDA, Daria J, MARGOLIS, David M

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Comparing perceptions of student abilities in diabetes self-management education and support among students, faculty and patients von Augustine, Jill, Thurston, Maria Miller, Gates, Adam W., Manigault, Kendra R.

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First demonstration of cerebrospinal fluid and plasma A beta lowering with oral administration of a beta-site amyloid precursor protein-cleaving enzyme 1 inhibitor in nonhuman prim... von Sankaranarayanan, Sethu, Holahan, Marie A, Colussi, Dennis, Crouthamel, Ming-Chih, Devanarayan, Viswanath, Ellis, Joan, Espeseth, Amy, Gates, Adam T, Graham, Samuel L, Gregro, Allison R, Hazuda, Daria, Hochman, Jerome H, Holloway, Katharine, Jin, Lixia, Kahana, Jason, Lai, Ming-tain, Lineberger, Janet, McGaughey, Georgia, Moore, Keith P, Nantermet, Philippe, Pietrak, Beth, Price, Eric A, Rajapakse, Hemaka, Stauffer, Shaun, Steinbeiser, Melissa A, Seabrook, Guy, Selnick, Harold G, Shi, Xiao-Ping, Stanton, Matthew G, Swestock, John, Tugusheva, Katherine, Tyler, Keala X, Vacca, Joseph P, Wong, Jacky, Wu, Guoxin, Xu, Min, Cook, Jacquelynn J, Simon, Adam J

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ROCK Controls Matrix Synthesis in Vascular Smooth Muscle Cells: Coupling Vasoconstriction to Vascular Remodeling von Chapados, Rene, Abe, Khotaro, Ihida-Stansbury, Kaori, McKean, David, Gates, Adam T, Kern, Michael, Merklinger, Sandra, Elliott, John, Plant, Anne, Shimokawa, Hiroaki, Jones, Peter Lloyd

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Resistance Profile of a Hepatitis C Virus RNA-Dependent RNA Polymerase Benzothiadiazine Inhibitor von NGUYEN, Tammy T, GATES, Adam T, GUTSHALL, Lester L, JOHNSTON, Victor K, BAOHUA GU, DUFFY, Kevin J, SARISKY, Robert T

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LRRTM3 Promotes Processing of Amyloid-Precursor Protein by BACE1 and Is a Positional Candidate Gene for Late-Onset Alzheimer's Disease von Majercak, John, Ray, William J., Espeseth, Amy, Simon, Adam, Shi, Xiao-Ping, Wolffe, Carrie, Getty, Krista, Marine, Shane, Stec, Erica, Ferrer, Marc, Strulovici, Berta, Bartz, Steven, Gates, Adam, Xu, Min, Huang, Qian, Ma, Lei, Shughrue, Paul, Burchard, Julja, Colussi, Dennis, Pietrak, Beth, Kahana, Jason, Beher, Dirk, Rosahl, Thomas, Shearman, Mark, Hazuda, Daria, Sachs, Alan B., Koblan, Kenneth S., Seabrook, Guy R., Stone, David J.

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Replication Studies Using Genotype 1a Subgenomic Hepatitis C Virus Replicons von Gu, Baohua, Gates, Adam T, Isken, Olaf, Behrens, Sven-Erik, Sarisky, Robert T

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MK-5172, a Selective Inhibitor of Hepatitis C Virus NS3/4a Protease with Broad Activity across Genotypes and Resistant Variants von Summa, Vincenzo, Ludmerer, Steven W, McCauley, John A, Fandozzi, Christine, Burlein, Christine, Claudio, Giuliano, Coleman, Paul J, DiMuzio, Jillian M, Ferrara, Marco, Filippo, Marcello Di, Gates, Adam T, Graham, Donald J, Harper, Steven, Hazuda, Daria J, Huang, Qian, McHale, Carolyn, Monteagudo, Edith, Pucci, Vincenzo, Rowley, Michael, Rudd, Michael T, Soriano, Aileen, Stahlhut, Mark W, Vacca, Joseph P, Olsen, David B, Liverton, Nigel J, Carroll, Steven S

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Hit selection with false discovery rate control in genome-scale RNAi screens von Zhang, Xiaohua Douglas, Kuan, Pei Fen, Ferrer, Marc, Shu, Xiaohua, Liu, Yingxue C, Gates, Adam T, Kunapuli, Priya, Stec, Erica M, Xu, Min, Marine, Shane D, Holder, Daniel J, Strulovici, Berta, Heyse, Joseph F, Espeseth, Amy S

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Sequence requirements for the development of a chimeric HCV replicon system von Gates, Adam T., Sarisky, Robert T., Gu, Baohua

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3-(1,1-Dioxo-2H-(1,2,4)-benzothiadiazin-3-yl)-4-hydroxy-2(1H)-quinolinones, Potent Inhibitors of Hepatitis C Virus RNA-Dependent RNA Polymerase von Tedesco, Rosanna, Shaw, Antony N, Bambal, Ramesh, Chai, Deping, Concha, Nestor O, Darcy, Michael G, Dhanak, Dashyant, Fitch, Duke M, Gates, Adam, Gerhardt, Warren G, Halegoua, Dina L, Han, Chao, Hofmann, Glenn A, Johnston, Victor K, Kaura, Arun C, Liu, Nannan, Keenan, Richard M, Lin-Goerke, Juili, Sarisky, Robert T, Wiggall, Kenneth J, Zimmerman, Michael N, Duffy, Kevin J

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Identification and Biological Characterization of Heterocyclic Inhibitors of the Hepatitis C Virus RNA-dependent RNA Polymerase von Dhanak, Dashyant, Duffy, Kevin J., Johnston, Victor K., Lin-Goerke, Juili, Darcy, Michael, Shaw, Antony N., Gu, Baohua, Silverman, Carol, Gates, Adam T., Nonnemacher, Michael R., Earnshaw, David L., Casper, David J., Kaura, Arun, Baker, Audrey, Greenwood, Cathy, Gutshall, Lester L., Maley, Derrick, DelVecchio, Alfred, Macarron, Ricardo, Hofmann, Glenn A., Alnoah, Zaid, Cheng, Hung-Yuan, Chan, George, Khandekar, Sanjay, Keenan, Richard M., Sarisky, Robert T.

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P2-Quinazolinones and Bis-Macrocycles as New Templates for Next-Generation Hepatitis C Virus NS3/4a Protease Inhibitors: Discovery of MK-2748 and MK-6325 von Rudd, Michael T., Butcher, John W., Nguyen, Kevin T., McIntyre, Charles J., Romano, Joseph J., Gilbert, Kevin F., Bush, Kimberly J., Liverton, Nigel J., Holloway, M. Katharine, Harper, Steven, Ferrara, Marco, DiFilippo, Marcello, Summa, Vincenzo, Swestock, John, Fritzen, Jeff, Carroll, Steven S., Burlein, Christine, DiMuzio, Jillian M., Gates, Adam, Graham, Donald J., Huang, Qian, McClain, Stephanie, McHale, Carolyn, Stahlhut, Mark W., Black, Stuart, Chase, Robert, Soriano, Aileen, Fandozzi, Christine M., Taylor, Anne, Trainor, Nicole, Olsen, David B., Coleman, Paul J., Ludmerer, Steven W., McCauley, John A.

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Substituted benzothiadizine inhibitors of Hepatitis C virus polymerase von Shaw, Antony N., Tedesco, Rosanna, Bambal, Ramesh, Chai, Deping, Concha, Nestor O., Darcy, Michael G., Dhanak, Dashyant, Duffy, Kevin J., Fitch, Duke M., Gates, Adam, Johnston, Victor K., Keenan, Richard M., Lin-Goerke, Juili, Liu, Nannan, Sarisky, Robert T., Wiggall, Kenneth J., Zimmerman, Michael N.

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Synthesis and biological activity of heteroaryl 3-(1,1-dioxo-2H-(1,2,4)-benzothiadizin-3-yl)-4-hydroxy-2(1H)-quinolinone derivatives as hepatitis C virus NS5B polymerase inhibitors von Tedesco, Rosanna, Chai, Deping, Darcy, Michael G., Dhanak, Dashyant, Fitch, Duke M., Gates, Adam, Johnston, Victor K., Keenan, Richard M., Lin-Goerke, Juili, Sarisky, Robert T., Shaw, Antony N., Valko, Klara L., Wiggall, Kenneth J., Zimmerman, Michael N., Duffy, Kevin J.

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Development of macrocyclic inhibitors of HCV NS3/4A protease with cyclic constrained P2–P4 linkers von Rudd, Michael T., McIntyre, Charles J., Romano, Joseph J., Butcher, John W., Holloway, M. Katharine, Bush, Kimberly, Nguyen, Kevin T., Gilbert, Kevin F., Lyle, Terry A., Liverton, Nigel J., Wan, Bang-Lin, Summa, Vincenzo, Harper, Steven, Rowley, Michael, Vacca, Joseph P., Carroll, Steven S., Burlein, Christine, DiMuzio, Jillian M., Gates, Adam, Graham, Donald J., Huang, Qian, Ludmerer, Steven W., McClain, Stephanie, McHale, Carolyn, Stahlhut, Mark, Fandozzi, Christine, Taylor, Anne, Trainor, Nicole, Olsen, David B., McCauley, John A.

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Development of potent macrocyclic inhibitors of genotype 3a HCV NS3/4A protease von Rudd, Michael T., McCauley, John A., Romano, Joseph J., Butcher, John W., Bush, Kimberly, McIntyre, Charles J., Nguyen, Kevin T., Gilbert, Kevin F., Lyle, Terry A., Holloway, M. Katharine, Wan, Bang-Lin, Vacca, Joseph P., Summa, Vincenzo, Harper, Steven, Rowley, Michael, Carroll, Steven S., Burlein, Christine, DiMuzio, Jillian M., Gates, Adam, Graham, Donald J., Huang, Qian, Ludmerer, Steven W., McClain, Stephanie, McHale, Carolyn, Stahlhut, Mark, Fandozzi, Christine, Taylor, Anne, Trainor, Nicole, Olsen, David B., Liverton, Nigel J.

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Development of macrocyclic inhibitors of HCV NS3/4A protease with cyclic constrained P2aP4 linkers von Rudd, Michael T, McIntyre, Charles J, Romano, Joseph J, Butcher, John W, Holloway, MKatharine, Bush, Kimberly, Nguyen, Kevin T, Gilbert, Kevin F, Lyle, Terry A, Liverton, Nigel J, Wan, Bang-Lin, Summa, Vincenzo, Harper, Steven, Rowley, Michael, Vacca, Joseph P, Carroll, Steven S, Burlein, Christine, DiMuzio, Jillian M, Gates, Adam, Graham, Donald J, Huang, Qian, Ludmerer, Steven W, McClain, Stephanie, McHale, Carolyn, Stahlhut, Mark, Fandozzi, Christine, Taylor, Anne, Trainor, Nicole, Olsen, David B, McCauley, John A

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