DRAM, a p53-Induced Modulator of Autophagy, Is Critical for Apoptosis von Crighton, Diane, Wilkinson, Simon, O'Prey, Jim, Syed, Nelofer, Smith, Paul, Harrison, Paul R., Gasco, Milena, Garrone, Ornella, Crook, Tim, Ryan, Kevin M.

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Polymorphism in wild-type p53 modulates response to chemotherapy in vitro and in vivo von SULLIVAN, Alexandra, SYED, Nelofer, CROOK, Tim, GASCO, Milena, BERGAMASCHI, Daniele, TRIGIANTE, Giuseppe, ATTARD, Marlene, HILLER, Louise, FARRELL, Paul J, SMITH, Paul, XIN LU

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The prolyl isomerase Pin1 orchestrates p53 acetylation and dissociation from the apoptosis inhibitor iASPP von Sal, Giannino Del, Mantovani, Fiamma, Tocco, Francesca, Girardini, Javier, Smith, Paul, Gasco, Milena, Lu, Xin, Crook, Tim

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iASPP preferentially binds p53 proline-rich region and modulates apoptotic function of codon 72-polymorphic p53 von Lu, Xin, Bergamaschi, Daniele, Samuels, Yardena, Sullivan, Alexandra, Zvelebil, Marketa, Breyssens, Hilde, Bisso, Andrea, Del Sal, Giannino, Syed, Nelofer, Smith, Paul, Gasco, Milena, Crook, Tim

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p53 polymorphism influences response in cancer chemotherapy via modulation of p73-dependent apoptosis von Bergamaschi, Daniele, Gasco, Milena, Hiller, Louise, Sullivan, Alexandra, Syed, Nelofer, Trigiante, Giuseppe, Yulug, Isik, Merlano, Marco, Numico, Gianmauro, Comino, Alberto, Attard, Marlene, Reelfs, Olivier, Gusterson, Barry, Bell, Alexandra K, Heath, Victoria, Tavassoli, Mahvash, Farrell, Paul J, Smith, Paul, Lu, Xin, Crook, Tim

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Survival prediction and frequency of anticancer treatment in cancer patients hospitalized due to acute conditions. Role of clinical parameters and PaP score von Numico, Gianmauro, Occelli, Marcella, Russi, Elvio G., Silvestris, Nicola, Pasero, Raffaella, Fea, Elena, Granetto, Cristina, Di Costanzo, Gianna, Colantonio, Ida, Gasco, Milena, Garrone, Ornella, Polla, Valentina, Merlano, Marco C.

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Epigenetic Inactivation Implies Independent Functions for Insulin-like Growth Factor Binding Protein (IGFBP)-Related Protein 1 and the Related IGFBPL1 in Inhibiting Breast Cancer P... von SMITH, Paul, NICHOLSON, Linda J, SYED, Nelofer, PAYNE, Annette, HILLER, Louise, GARRONE, Ornella, OCCELLI, Marcella, GASCO, Milena, CROOK, Tim

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Concomitant inactivation of p53 and Chk2 in breast cancer von SULLIVAN, Alexandra, YUILLE, Martin, YULUG, Isik, EVANS, Abigail, OZCELIK, Tayfun, GASCO, Milena, CROOK, Tim, REPELLIN, Claire, REDDY, Archana, REELFS, Olivier, BELL, Alexandra, DUNNE, Barbara, GUSTERSON, Barry A, OSIN, Peter, FARRELL, Paul J

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p53 family members and chemoresistance in cancer: what we know and what we need to know von Gasco, Milena, Crook, Tim

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A Phase I-II Preoperative Biomarker Trial of Fenretinide in Ascitic Ovarian Cancer von COLOMBO, Nicoletta, FORMELLI, Franca, GUERRIERI-GONZAGA, Aliana, VIALE, Giuseppe, DECENSI, Andrea, CANTU, Maria Grazia, PARMA, Gabriella, GASCO, Milena, ARGUSTI, Alessandra, SANTINELLI, Alfredo, MONTIRONI, Rodolfo, CAVADINI, Elena, BAGLIETTO, Laura

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The p53 pathway in breast cancer von Gasco, Milena, Shami, Shukri, Crook, Tim

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Identification of CDK10 as an Important Determinant of Resistance to Endocrine Therapy for Breast Cancer von Iorns, Elizabeth, Turner, Nicholas C., Elliott, Richard, Syed, Nelofer, Garrone, Ornella, Gasco, Milena, Tutt, Andrew N.J., Crook, Tim, Lord, Christopher J., Ashworth, Alan

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Tip60 is a haplo-insufficient tumour suppressor required for an oncogene-induced DNA damage response von Bennett, Samantha, Wark, Landon, Gorrini, Chiara, Squatrito, Massimo, Capra, Maria, Mai, Sabine, Crook, Tim, Luise, Chiara, Marchesi, Francesco, Verrecchia, Alessandro, Gasco, Milena, Cesaroni, Matteo, Martinato, Francesca, Amati, Bruno, Syed, Nelofer, Lough, John, Perna, Daniele, Nuciforo, Paolo, Confalonieri, Stefano, Sardella, Domenico, Scanziani, Eugenio

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Functional regulation of p73 and p63: development and cancer von Melino, Gerry, Lu, Xin, Gasco, Milena, Crook, Tim, Knight, Richard A

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The p53 network in head and neck cancer von Gasco, Milena, Crook, Tim

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Prospective evaluation of major vascular events in patients with nonsmall cell lung carcinoma treated with cisplatin and gemcitabine von Numico, Gianmauro, Garrone, Ornella, Dongiovanni, Vincenzo, Silvestris, Nicola, Colantonio, Ida, Di Costanzo, Gianna, Granetto, Cristina, Occelli, Marcella, Fea, Elena, Heouaine, Abdelamid, Gasco, Milena, Merlano, Marco

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Carboplatin and Weekly Paclitaxel in Non-small Cell Lung Cancer Patients Unfit for or Pretreated with Chemotherapy von NUMICO, Gianmauro, COLANTONIO, Ida, RUSSI, Elvio, MERLANO, Marco, GASCO, Milena, BERTELLI, Gianfilippo, GARRONE, Ornella, OCCELLI, Marcella, FEA, Elena, DI COSTANZO, Gianna, GRANETTO, Cristina, HEOUAINE, Abdelamid

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Epigenetic downregulation of human disabled homolog 2 switches TGF-beta from a tumor suppressor to a tumor promoter von Hannigan, Adèle, Smith, Paul, Kalna, Gabriela, Lo Nigro, Cristiana, Orange, Clare, O'Brien, Darren I, Shah, Reshma, Syed, Nelofer, Spender, Lindsay C, Herrera, Blanca, Thurlow, Johanna K, Lattanzio, Laura, Monteverde, Martino, Maurer, Meghan E, Buffa, Francesca M, Mann, Jelena, Chu, David C K, West, Catharine M L, Patridge, Max, Oien, Karin A, Cooper, Jonathan A, Frame, Margaret C, Harris, Adrian L, Hiller, Louise, Nicholson, Linda J, Gasco, Milena, Crook, Tim, Inman, Gareth J

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Coincident inactivation of 14-3-3σ and p16INK4a is an early event in vulval squamous neoplasia von GASCO, Milena, SULLIVAN, Alex, REPELLIN, Claire, BROOKS, Louise, FARRELL, Paul J, TIDY, John A, DUNNE, Barbara, GUSTERSON, Barry, EVANS, David J, CROOK, Tim

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MDM2 309 polymorphism predicts outcome in platinum-treated locally advanced head and neck cancer von Vivenza, Daniela, Gasco, Milena, Monteverde, Martino, Lattanzio, Laura, Syed, Nelofer, Colantonio, Ida, Denaro, Nerina, Natoli, Guido, Comino, Alberto, Russi, Elvio, Merlano, Marco, Crook, Tim, Lo Nigro, Cristiana

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