Higher Nodal expression is often associated with poorer survival in patients diagnosed with melanoma and treated with anti-PD1 therapy von Gascard, Philippe D, Wang, Xianhong, Nosrati, Mehdi, Kim, Kevin B, Kashani-Sabet, Mohammed, Tlsty, Thea D, Leong, Stanley P, Hendrix, Mary J C

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Differential domain evolution and complex RNA processing in a family of paralogous EPB41 (protein 4.1) genes facilitate expression of diverse tissue-specific isoforms von Parra, Marilyn, Gee, Sherry, Chan, Nadine, Ryaboy, Dmitriy, Dubchak, Inna, Mohandas, Narla, Gascard, Philippe D., Conboy, John G.

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223 IMMUNE CELL PHENOTYPING IN BARRETT'S ESOPHAGUS IN PATIENTS PRIOR AND AT TIME OF PROGRESSION von Lin, Meng-Lay, Hickey, John W., Schürch, Christian M., Passman, Adam M., Carlotti, Emanuela, Devkumar, Shruthi, Hackett, Richard J., Rodriguez-Justo, Manuel, Novelli, Marco, Jansen, Marnix, Gascard, Philippe D., Tlsty, Thea D., McDonald, Stuart A.

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Su1246 USING MASSIVE MULTIPLEX IMMUNOFLUORESENCE (CODEX) TO DEFINE THE INTRAEPITHELIAL IMMUNE CELL MICROENVIRONMENT IN BARRETT'S ESOPHAGUS IN PATIENTS THAT HAVE PROGRESSED TO CANCE... von Lin, Meng-Lay, Hickey, John W., Passman, Adam M., Carlotti, Emanuela, Derwa, Yannick H., Devkumar, Shruthi, Gascard, Philippe D., Schürch, Christian M., Novelli, Marco, Rodriguez-Justo, Manuel, McLean, Mairi H., Tlsty, Thea D., Ferri, Lorenzo E., Nolan, Garry P., McDonald, Stuart A.

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Tu1165: THE IMMUNE CELL MICROENVIRONMENT IS DIFFERENTIALLY-ALTERED ACCORDING TO DIVERSE EPITHELIAL LANDSCAPES IN THE PROGRESSION TO CANCER IN BARRETT OESOPHAGUS von Lin, Meng-Lay, Hickey, John W., Schürch, Christian M., Carlotti, Emanuela, Passman, Adam M., Hackett, Richard J., Devkumar, Shruthi, Evans, James A., Gascard, Philippe D., Tlsty, Thea D., Ferri, Lorenzo E., Nolan, Garry P., McDonald, Stuart A.

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970: DISCRETE FIBROBLAST SUBSETS NURTURE GASTRIC CARCINOGENESIS von Lee, Su-Hyung, Panta, Ela W. Contreras, Gibbs, David L., Won, Yoonkyung, Min, Jimin, Zhang, Changqing, Ferri, Lorenzo E., Sangwan, Veena, Ragoussis, Ioannis, Camilleri-Broet, Sophie, Caruso, Joseph, Strasser, Michael, Gascard, Philippe D., Huang, Sui, Tlsty, Thea D., Choi, Eunyoung, Goldenring, James R.

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Cytoskeletal Proteins in Heart Muscle von Pinder, Jennifer C, Taylor-Harris, Pamela M, Hayes, Nandini V L, Gascard, Philippe D, Maggs, Alison M, Baines, Anthony J

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Carcinoma-associated fibroblasts: orchestrating the composition of malignancy von Gascard, Philippe, Tlsty, Thea D

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Stromal directives can control cancer von Tlsty, Thea D, Gascard, Philippe

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Stromal directives can control cancer: Could reprogramming the pretumor microenvironment transform cancer care? von Tlsty, Thea D., Gascard, Philippe

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Rare somatic cells from human breast tissue exhibit extensive lineage plasticity von Roy, Somdutta, Gascard, Philippe, Dumont, Nancy, Zhao, Jianxin, Pan, Deng, Petrie, Sarah, Margeta, Marta, Tlsty, Thea D.

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Integrative analysis of 111 reference human epigenomes von Kundaje, Anshul, Meuleman, Wouter, Ernst, Jason, Bilenky, Misha, Yen, Angela, Heravi-Moussavi, Alireza, Kheradpour, Pouya, Zhang, Zhizhuo, Wang, Jianrong, Ziller, Michael J., Amin, Viren, Whitaker, John W., Schultz, Matthew D., Ward, Lucas D., Sarkar, Abhishek, Quon, Gerald, Sandstrom, Richard S., Eaton, Matthew L., Wu, Yi-Chieh, Pfenning, Andreas R., Wang, Xinchen, Claussnitzer, Melina, Liu, Yaping, Coarfa, Cristian, Harris, R. Alan, Shoresh, Noam, Epstein, Charles B., Gjoneska, Elizabeta, Leung, Danny, Xie, Wei, Hawkins, R. David, Lister, Ryan, Hong, Chibo, Gascard, Philippe, Mungall, Andrew J., Moore, Richard, Chuah, Eric, Tam, Angela, Canfield, Theresa K., Hansen, R. Scott, Kaul, Rajinder, Sabo, Peter J., Bansal, Mukul S., Carles, Annaick, Dixon, Jesse R., Farh, Kai-How, Feizi, Soheil, Karlic, Rosa, Kim, Ah-Ram, Kulkarni, Ashwinikumar, Li, Daofeng, Lowdon, Rebecca, Elliott, GiNell, Mercer, Tim R., Neph, Shane J., Onuchic, Vitor, Polak, Paz, Rajagopal, Nisha, Ray, Pradipta, Sallari, Richard C., Siebenthall, Kyle T., Sinnott-Armstrong, Nicholas A., Stevens, Michael, Thurman, Robert E., Wu, Jie, Zhang, Bo, Zhou, Xin, Beaudet, Arthur E., Boyer, Laurie A., De Jager, Philip L., Farnham, Peggy J., Fisher, Susan J., Haussler, David, Jones, Steven J. M., Li, Wei, Marra, Marco A., McManus, Michael T., Sunyaev, Shamil, Thomson, James A., Tlsty, Thea D., Tsai, Li-Huei, Wang, Wei, Waterland, Robert A., Zhang, Michael Q., Chadwick, Lisa H., Bernstein, Bradley E., Costello, Joseph F., Ecker, Joseph R., Hirst, Martin, Meissner, Alexander, Milosavljevic, Aleksandar, Ren, Bing, Stamatoyannopoulos, John A., Wang, Ting, Kellis, Manolis

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Functional DNA methylation differences between tissues, cell types, and across individuals discovered using the M&M algorithm von Zhang, Bo, Zhou, Yan, Lin, Nan, Lowdon, Rebecca F, Hong, Chibo, Nagarajan, Raman P, Cheng, Jeffrey B, Li, Daofeng, Stevens, Michael, Lee, Hyung Joo, Xing, Xiaoyun, Zhou, Jia, Sundaram, Vasavi, Elliott, Ginell, Gu, Junchen, Shi, Taoping, Gascard, Philippe, Sigaroudinia, Mahvash, Tlsty, Thea D, Kadlecek, Theresa, Weiss, Arthur, O'Geen, Henriette, Farnham, Peggy J, Maire, Cécile L, Ligon, Keith L, Madden, Pamela A F, Tam, Angela, Moore, Richard, Hirst, Martin, Marra, Marco A, Zhang, Baoxue, Costello, Joseph F, Wang, Ting

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Intermediate DNA methylation is a conserved signature of genome regulation von Elliott, GiNell, Hong, Chibo, Xing, Xiaoyun, Zhou, Xin, Li, Daofeng, Coarfa, Cristian, Bell, Robert J.A., Maire, Cecile L., Ligon, Keith L., Sigaroudinia, Mahvash, Gascard, Philippe, Tlsty, Thea D., Harris, R. Alan, Schalkwyk, Leonard C., Bilenky, Misha, Mill, Jonathan, Farnham, Peggy J., Kellis, Manolis, Marra, Marco A., Milosavljevic, Aleksandar, Hirst, Martin, Stormo, Gary D., Wang, Ting, Costello, Joseph F.

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The clonal and mutational evolution spectrum of primary triple-negative breast cancers von Shah, Sohrab P., Roth, Andrew, Goya, Rodrigo, Oloumi, Arusha, Ha, Gavin, Zhao, Yongjun, Turashvili, Gulisa, Ding, Jiarui, Tse, Kane, Haffari, Gholamreza, Bashashati, Ali, Prentice, Leah M., Khattra, Jaswinder, Burleigh, Angela, Yap, Damian, Bernard, Virginie, McPherson, Andrew, Shumansky, Karey, Crisan, Anamaria, Giuliany, Ryan, Heravi-Moussavi, Alireza, Rosner, Jamie, Lai, Daniel, Birol, Inanc, Varhol, Richard, Tam, Angela, Dhalla, Noreen, Zeng, Thomas, Ma, Kevin, Chan, Simon K., Griffith, Malachi, Moradian, Annie, Cheng, S.-W. Grace, Morin, Gregg B., Watson, Peter, Gelmon, Karen, Chia, Stephen, Chin, Suet-Feung, Curtis, Christina, Rueda, Oscar M., Pharoah, Paul D., Damaraju, Sambasivarao, Mackey, John, Hoon, Kelly, Harkins, Timothy, Tadigotla, Vasisht, Sigaroudinia, Mahvash, Gascard, Philippe, Tlsty, Thea, Costello, Joseph F., Meyer, Irmtraud M., Eaves, Connie J., Wasserman, Wyeth W., Jones, Steven, Huntsman, David, Hirst, Martin, Caldas, Carlos, Marra, Marco A., Aparicio, Samuel

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Epigenetic and transcriptional determinants of the human breast von Gascard, Philippe, Bilenky, Misha, Sigaroudinia, Mahvash, Zhao, Jianxin, Li, Luolan, Carles, Annaick, Delaney, Allen, Tam, Angela, Kamoh, Baljit, Cho, Stephanie, Griffith, Malachi, Chu, Andy, Robertson, Gordon, Cheung, Dorothy, Li, Irene, Heravi-Moussavi, Alireza, Moksa, Michelle, Mingay, Matthew, Hussainkhel, Angela, Davis, Brad, Nagarajan, Raman P., Hong, Chibo, Echipare, Lorigail, O’Geen, Henriette, Hangauer, Matthew J., Cheng, Jeffrey B., Neel, Dana, Hu, Donglei, McManus, Michael T., Moore, Richard, Mungall, Andrew, Ma, Yussanne, Plettner, Patrick, Ziv, Elad, Wang, Ting, Farnham, Peggy J., Jones, Steven J.M., Marra, Marco A., Tlsty, Thea D., Costello, Joseph F., Hirst, Martin

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Apposition of Fibroblasts With Metaplastic Gastric Cells Promotes Dysplastic Transition von Lee, Su-Hyung, Contreras Panta, Ela W., Gibbs, David, Won, Yoonkyung, Min, Jimin, Zhang, Changqing, Roland, Joseph T., Hong, Se-Hoon, Sohn, Yoojin, Krystofiak, Evan, Jang, Bogun, Ferri, Lorenzo, Sangwan, Veena, Ragoussis, Jiannis, Camilleri-Broët, Sophie, Caruso, Joseph, Chen-Tanyolac, Chira, Strasser, Michael, Gascard, Philippe, Tlsty, Thea D., Huang, Sui, Choi, Eunyoung, Goldenring, James R.

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DNA hypomethylation within specific transposable element families associates with tissue-specific enhancer landscape von Xie, Mingchao, Hong, Chibo, Zhang, Bo, Lowdon, Rebecca F, Xing, Xiaoyun, Li, Daofeng, Zhou, Xin, Lee, Hyung Joo, Maire, Cecile L, Ligon, Keith L, Gascard, Philippe, Sigaroudinia, Mahvash, Tlsty, Thea D, Kadlecek, Theresa, Weiss, Arthur, O'Geen, Henriette, Farnham, Peggy J, Madden, Pamela A F, Mungall, Andrew J, Tam, Angela, Kamoh, Baljit, Cho, Stephanie, Moore, Richard, Hirst, Martin, Marra, Marco A, Costello, Joseph F, Wang, Ting

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Mapping hormone-regulated cell-cell interaction networks in the human breast at single-cell resolution von Murrow, Lyndsay M., Weber, Robert J., Caruso, Joseph A., McGinnis, Christopher S., Phong, Kiet, Gascard, Philippe, Rabadam, Gabrielle, Borowsky, Alexander D., Desai, Tejal A., Thomson, Matthew, Tlsty, Thea, Gartner, Zev J.

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Loss of PPARγ activity characterizes early protumorigenic stromal reprogramming and dictates the therapeutic window of opportunity von Caruso, Joseph A, Wang, Xianhong, Murrow, Lyndsay M, Rodriguez, Carlos Ivan, Chen-Tanyolac, Chira, Vu, Lisa, Chen, Yunn-Yi, Gascard, Philippe, Gartner, Zev J, Kerlikowske, Karla, Tlsty, Thea D

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