Cell-Cycle Therapeutics Come of Age von Ingham, Matthew, Schwartz, Gary K

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Prevalence of tumor-infiltrating lymphocytes and PD-L1 expression in the soft tissue sarcoma microenvironment von D’Angelo, Sandra P., MD, Shoushtari, Alexander N., MD, Agaram, Narasimhan P., MD, Kuk, Deborah, Qin, Li-Xuan, PhD, Carvajal, Richard D., MD, Dickson, Mark A., MD, Gounder, Mrinal, MD, Keohan, Mary Louise, MD, Schwartz, Gary K., MD, Tap, William D., MD

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Targeting the Cell Cycle: A New Approach to Cancer Therapy von SCHWARTZ, Gary K, SHAH, Manish A

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Olaratumab and doxorubicin versus doxorubicin alone for treatment of soft-tissue sarcoma: an open-label phase 1b and randomised phase 2 trial von Tap, William D, Dr, Jones, Robin L, MD, Van Tine, Brian A, MD, Chmielowski, Bartosz, MD, Elias, Anthony D, Prof, Adkins, Douglas, Prof, Agulnik, Mark, MD, Cooney, Matthew M, MD, Livingston, Michael B, MD, Pennock, Gregory, MD, Hameed, Meera R, MD, Shah, Gaurav D, MD, Qin, Amy, PhD, Shahir, Ashwin, MD, Cronier, Damien M, PhD, Ilaria, Robert, MD, Conti, Ilaria, MD, Cosaert, Jan, MD, Schwartz, Gary K, Prof

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Emerging Targeted and Immune-Based Therapies in Sarcoma von Pollack, Seth M, Ingham, Matthew, Spraker, Matthew B, Schwartz, Gary K

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Phase II Trial of the CDK4 Inhibitor PD0332991 in Patients With Advanced CDK4-Amplified Well-Differentiated or Dedifferentiated Liposarcoma von DICKSON, Mark A, TAP, William D, USTOYEV, Yelena, CRAGO, Aimee M, SINGER, Samuel, SCHWARTZ, Gary K, KEOHAN, Mary Louise, D'ANGELO, Sandra P, GOUNDER, Mrinal M, ANTONESCU, Cristina R, LANDA, Jonathan, QIN, Li-Xuan, RATHBONE, Dustin D, CONDY, Mercedes M

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Patient‐derived xenografts for individualized care in advanced sarcoma von Stebbing, Justin, Paz, Keren, Schwartz, Gary K., Wexler, Leonard H., Maki, Robert, Pollock, Raphael E., Morris, Ronnie, Cohen, Richard, Shankar, Arjun, Blackman, Glen, Harding, Victoria, Vasquez, David, Krell, Jonathan, Ciznadija, Daniel, Katz, Amanda, Sidransky, David

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Crizotinib, a c-Met inhibitor, prevents metastasis in a metastatic uveal melanoma model von Surriga, Oliver, Rajasekhar, Vinagolu K, Ambrosini, Grazia, Dogan, Yildrim, Huang, Ruimin, Schwartz, Gary K

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The Potential for Isocitrate Dehydrogenase Mutations to Produce 2-Hydroxyglutarate Depends on Allele Specificity and Subcellular Compartmentalization von Ward, Patrick S., Lu, Chao, Cross, Justin R., Abdel-Wahab, Omar, Levine, Ross L., Schwartz, Gary K., Thompson, Craig B.

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Multimodal single-cell and whole-genome sequencing of small, frozen clinical specimens von Wang, Yiping, Fan, Joy Linyue, Melms, Johannes C., Amin, Amit Dipak, Georgis, Yohanna, Barrera, Irving, Ho, Patricia, Tagore, Somnath, Abril-Rodríguez, Gabriel, He, Siyu, Jin, Yinuo, Biermann, Jana, Hofree, Matan, Caprio, Lindsay, Berhe, Simon, Khan, Shaheer A., Henick, Brian S., Ribas, Antoni, Macosko, Evan Z., Chen, Fei, Taylor, Alison M., Schwartz, Gary K., Carvajal, Richard D., Azizi, Elham, Izar, Benjamin

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Alternative transcription initiation leads to expression of a novel ALK isoform in cancer von Wiesner, Thomas, Lee, William, Obenauf, Anna C., Ran, Leili, Murali, Rajmohan, Zhang, Qi Fan, Wong, Elissa W. P., Hu, Wenhuo, Scott, Sasinya N., Shah, Ronak H., Landa, Iñigo, Button, Julia, Lailler, Nathalie, Sboner, Andrea, Gao, Dong, Murphy, Devan A., Cao, Zhen, Shukla, Shipra, Hollmann, Travis J., Wang, Lu, Borsu, Laetitia, Merghoub, Taha, Schwartz, Gary K., Postow, Michael A., Ariyan, Charlotte E., Fagin, James A., Zheng, Deyou, Ladanyi, Marc, Busam, Klaus J., Berger, Michael F., Chen, Yu, Chi, Ping

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Chemotherapy in the management of advanced cutaneous malignant melanoma von Luke, Jason J., MD, Schwartz, Gary K., MD

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Composite grading algorithm for the National Cancer Institute’s Patient-Reported Outcomes version of the Common Terminology Criteria for Adverse Events (PRO-CTCAE) von Basch, Ethan, Becker, Claus, Rogak, Lauren J, Schrag, Deborah, Reeve, Bryce B, Spears, Patricia, Smith, Mary Lou, Gounder, Mrinal M, Mahoney, Michelle R, Schwartz, Gary K, Bennett, Antonia V, Mendoza, Tito R, Cleeland, Charles S, Sloan, Jeff A, Bruner, Deborah Watkins, Schwab, Gisela, Atkinson, Thomas M, Thanarajasingam, Gita, Bertagnolli, Monica M, Dueck, Amylou C

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Aurora Kinases: New Targets for Cancer Therapy von CARVAJAL, Richard D, TSE, Archie, SCHWARTZ, Gary K

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Down-regulation of the tumor suppressor miR-34a contributes to head and neck cancer by up-regulating the MET oncogene and modulating tumor immune evasion von Wu, Xun, Cheng, Yi-Shing Lisa, Matthen, Mathew, Yoon, Angela, Schwartz, Gary K, Bala, Shashi, Taylor, Alison M, Momen-Heravi, Fatemeh

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Phase II Study of Sorafenib in Patients With Metastatic or Recurrent Sarcomas von MAKI, Robert G, D'ADAMO, David R, TAKIMOTO, Chris H, KRAFT, Andrew S, ELIAS, Anthony D, BROCKSTEIN, Bruce, BLACHERE, Nathalie E, EDGAR, Mark A, SCHWARTZ, Lawrence H, QIN, Li-Xuan, ANTONESCU, Cristina R, SCHWARTZ, Gary K, KEOHAN, Mary L, SAULLE, Michael, SCHUETZE, Scott M, UNDEVIA, Samir D, LIVINGSTON, Michael B, COONEY, Matthew M, HENSLEY, Martee L, MITA, Monica M

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Multicenter Phase II Study of Irinotecan, Cisplatin, and Bevacizumab in Patients With Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma von SHAH, Manish A, RAMANATHAN, Ramesh K, SCHWARTZ, Gary K, KELSEN, David P, ILSON, David H, LEVNOR, Alissa, D'ADAMO, David, O'REILLY, Eileen, TSE, Archie, TROCOLA, Robin, SCHWARTZ, Lawrence, CAPANU, Marinela

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Genomic Profiling of Metastatic Uveal Melanoma and Clinical Results of a Phase I Study of the Protein Kinase C Inhibitor AEB071 von Piperno-Neumann, Sophie, Larkin, James, Carvajal, Richard D, Luke, Jason J, Schwartz, Gary K, Hodi, F Stephen, Sablin, Marie-Paule, Shoushtari, Alexander N, Szpakowski, Sebastian, Chowdhury, Niladri Roy, Brannon, A Rose, Ramkumar, Thiruvamoor, de Koning, Leanne, Derti, Adnan, Emery, Caroline, Yerramilli-Rao, Padmaja, Kapiteijn, Ellen

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Sustained Inhibition of Receptor Tyrosine Kinases and Macrophage Depletion by PLX3397 and Rapamycin as a Potential New Approach for the Treatment of MPNSTs von PATWARDHAN, Parag P, SURRIGA, Oliver, BECKMAN, Michael J, DE STANCHINA, Elisa, DEMATTEO, Ronald P, TAP, William D, SCHWARTZ, Gary K

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Cetuximab Shows Activity in Colorectal Cancer Patients With Tumors That Do Not Express the Epidermal Growth Factor Receptor by Immunohistochemistry von KI YOUNG CHUNG, JINRU SHIA, KLIMSTRA, David S, FRIDMAN, Daniel, KELSEN, David P, SALTZ, Leonard B, KEMENY, Nancy E, SHAH, Manish, SCHWARTZ, Gary K, TSE, Archie, HAMILTON, Audrey, PAN, Dorothy, SCHRAG, Deborah, SCHWARTZ, Lawrence

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