Structure-Based Design, Synthesis, and Biological Evaluation of Indomethacin Derivatives as Cyclooxygenase-2 Inhibiting Nitric Oxide Donors von Wey, Shiow-Jyi, Augustyniak, Michael E, Cochran, Edward D, Ellis, James L, Fang, Xinqin, Garvey, David S, Janero, David R, Letts, L. Gordon, Martino, Allison M, Melim, Terry L, Murty, Madhavi G, Richardson, Steward K, Schroeder, Joseph D, Selig, William M, Trocha, A. Mark, Wexler, Roseanne S, Young, Delano V, Zemtseva, Irina S, Zifcak, Brian M

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Synthesis and Selective Cyclooxygenase-2 Inhibitory Activity of a Series of Novel, Nitric Oxide Donor-Containing Pyrazoles von Ranatunge, Ramani R, Augustyniak, Michael, Bandarage, Upul K, Earl, Richard A, Ellis, James L, Garvey, David S, Janero, David R, Letts, L. Gordon, Martino, Allison M, Murty, Madhavi G, Richardson, Stewart K, Schroeder, Joseph D, Shumway, Matthew J, Tam, S. William, Trocha, A. Mark, Young, Delano V

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Synthesis and selective cyclooxygenase-2 (COX-2) inhibitory activity of a series of novel bicyclic pyrazoles von Ranatunge, Ramani R., Garvey, David S., Janero, David R., Letts, L.Gordon, Martino, Allison M., Murty, Madhavi G., Richardson, Stewart K., Young, Delano V., Zemetseva, Irina S.

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Synthesis and Structure−Activity Relationship of Novel, Highly Potent Metharyl and Methcycloalkyl Cyclooxygenase-2 (COX-2) Selective Inhibitors von Khanapure, Subhash P, Garvey, David S, Young, Delano V, Ezawa, Maiko, Earl, Richard A, Gaston, Rick D, Fang, Xinqin, Murty, Madhavi, Martino, Allison, Shumway, Matthew, Trocha, Mark, Marek, Przemyslaw, Tam, S. William, Janero, David R, Letts, L. Gordon

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Synthesis of the Nakanishi Ring-Locked Retinoid von Côté, Jamie B., Quach, Tan D., Demenev, Andrey P., Garvey, David S., Berman, Judd M.

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First Examples of Oxidizing Secondary Alcohols to Ketones in the Presence of the Disulfide Functional Group:  Synthesis of Novel Diketone Disulfides von Fang, Xinqin, Bandarage, Upul K, Wang, Tiansheng, Schroeder, Joseph D, Garvey, David S

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3-(2-Methoxytetrahydrofuran-2-yl)pyrazoles: a novel class of potent, selective cyclooxygenase-2 (COX-2) inhibitors von Ranatunge, Ramani R., Earl, Richard A., Garvey, David S., Janero, David R., Letts, L. Gordon, Martino, Allison M., Murty, Madhavi G., Richardson, Stewart K., Schwalb, David J., Young, Delano V., Zemtseva, Irina S.

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Preparation of functionalized tertiary thiols and nitrosothiols von Lin, Chia-En, Richardson, Stewart K., Wang, Weiheng, Wang, Tiansheng, Garvey, David S.

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Novel 3-Pyridyl Ethers with Subnanomolar Affinity for Central Neuronal Nicotinic Acetylcholine Receptors von Abreo, Melwyn A, Lin, Nan-Horng, Garvey, David S, Gunn, David E, Hettinger, Ann-Marie, Wasicak, James T, Pavlik, Patricia A, Martin, Yvonne C, Donnelly-Roberts, Diana L, Anderson, David J, Sullivan, James P, Williams, Michael, Arneric, Stephen P, Holladay, Mark W

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Nitrosothiol Esters of Diclofenac:  Synthesis and Pharmacological Characterization as Gastrointestinal-Sparing Prodrugs von Bandarage, Upul K, Chen, Liqing, Fang, Xinqin, Garvey, David S, Glavin, Alicia, Janero, David R, Letts, L. Gordon, Mercer, Gregory J, Saha, Joy K, Schroeder, Joseph D, Shumway, Matthew J, Tam, S. William

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Synthesis and anti-inflammatory activity of a series of N-substituted naproxen glycolamides: Nitric oxide-donor naproxen prodrugs von Ranatunge, Ramani R., Augustyniak, Michael E., Dhawan, Vijay, Ellis, James L., Garvey, David S., Janero, David R., Letts, L. Gordon, Richardson, Stewart K., Shumway, Mathew J., Trocha, A. Mark, Young, Delano V., Zemtseva, Irina S.

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Combination of Paclitaxel and Nitric Oxide as a Novel Treatment for the Reduction of Restenosis von Lin, Chia-En, Garvey, David S, Janero, David R, Letts, L. Gordon, Marek, Przemyslaw, Richardson, Stewart K, Serebryanik, Diana, Shumway, Matthew J, Tam, S. William, Trocha, A. Mark, Young, Delano V

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A-85380 [3-(2( S)-azetidinylmethoxy) pyridine]: In Vitro pharmacological properties of a novel, high affinity α4β2 nicotinic acetylcholine receptor ligand von Sullivan, James P., Donnelly-Roberts, Diana, Briggs, Clark A., Anderson, David J., Gopalakrishnan, Murali, Piattoni-Kaplan, Marietta, Campbell, Jeffrey E., McKenna, David G., Molinari, Edwardo, Hettinger, Ann-Marie, Garvey, David S., Wasicak, James T., Holladay, Mark W., Williams, Michael, Arneric, Stephen P.

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3-[4-(Methylsulfonyl)phenyl]-5-(trifluoromethyl)(2-pyridyl) Phenyl Ketone as a Potent and Orally Active Cyclooxygenase-2 Selective Inhibitor:  Synthesis and Biological Evaluation von Khanapure, Subhash P, Augustyniak, Michael E, Earl, Richard A, Garvey, David S, Letts, L. Gordon, Martino, Allison M, Murty, Madhavi G, Schwalb, David J, Shumway, Matthew J, Trocha, Andrzej M, Young, Delano V, Zemtseva, Irina S, Janero, David R

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A comparison of the cyclooxygenase inhibitor-NO donors (CINOD), NMI-1182 and AZD3582, using in vitro biochemical and pharmacological methods von Young, Delano V., Cochran, Edward D., Dhawan, Vijay, Earl, Richard A., Ellis, James L., Garvey, David S., Janero, David R., Khanapure, Subhash P., Letts, L. Gordon, Melim, Terry L., Murty, Madhavi G., Shumway, Matthew J., Wey, Shiow-Jyi, Zemtseva, Irina S., Selig, William M.

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l-Cysteine as a water-soluble cation scavenger in the removal of the 2,4,6-trimethoxybenzyl group from thiols von Lin, Chia-En, Richardson, Stewart K, Garvey, David S

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Nitric oxide-based molecular strategies for restenosis therapy von Lin, Chia-En, Janero, David R, Garvey, David S

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Structure−Activity Studies on 2-Methyl-3-(2(S)-pyrrolidinylmethoxy)pyridine (ABT-089):  An Orally Bioavailable 3-Pyridyl Ether Nicotinic Acetylcholine Receptor Ligand with Cognitio... von Lin, Nan-Horng, Gunn, David E, Ryther, Keith B, Garvey, David S, Donnelly-Roberts, Diana L, Decker, Michael W, Brioni, Jorge D, Buckley, Michael J, Rodrigues, A. David, Marsh, Kennan G, Anderson, David J, Buccafusco, Jerry J, Prendergast, Mark A, Sullivan, James P, Williams, Michael, Arneric, Stephen P, Holladay, Mark W

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Novel Isoxazoles which Interact with Brain Cholinergic Channel Receptors Have Intrinsic Cognitive Enhancing and Anxiolytic Activities von Garvey, David S, Wasicak, James T, Decker, Michael W, Brioni, Jorge D, Buckley, Michael J, Sullivan, James P, Carrera, George M, Holladay, Mark W, Arneric, Stephen P, Williams, Michael

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NMI-1182, a gastro-protective cyclo-oxygenase-inhibiting nitric oxide donor von Ellis, James L, Augustyniak, Michael E, Cochran, Edward D, Earl, Richard A, Garvey, David S, Gordon, Laura J, Janero, David R, Khanapure, Subhash P, Letts, L Gordon, Melim, Terry L, Murty, Madhavi G, Schwalb, David J, Shumway, Matthew J, Selig, William M, Trocha, A Mark, Young, Delano V, Zemtseva, Irina S

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