The genetics of the p53 pathway, apoptosis and cancer therapy von Bond, Gareth L, Vazquez, Alexei, Bond, Elisabeth E, Levine, Arnold J

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Expanding horizons: new roles for non-canonical RNA-binding proteins in cancer von Moore, Samantha, Järvelin, Aino I, Davis, Ilan, Bond, Gareth L, Castello, Alfredo

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Genomic hallmarks and therapeutic implications of G0 cell cycle arrest in cancer von Wiecek, Anna J, Cutty, Stephen J, Kornai, Daniel, Parreno-Centeno, Mario, Gourmet, Lucie E, Tagliazucchi, Guidantonio Malagoli, Jacobson, Daniel H, Zhang, Ping, Xiong, Lingyun, Bond, Gareth L, Barr, Alexis R, Secrier, Maria

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The importance of p53 pathway genetics in inherited and somatic cancer genomes von Stracquadanio, Giovanni, Wang, Xuting, Wallace, Marsha D., Grawenda, Anna M., Zhang, Ping, Hewitt, Juliet, Zeron-Medina, Jorge, Castro-Giner, Francesc, Tomlinson, Ian P., Goding, Colin R., Cygan, Kamil J., Fairbrother, William G., Thomas, Laurent F., Sætrom, Pål, Gemignani, Federica, Landi, Stefano, Schuster-Böckler, Benjamin, Bell, Douglas A., Bond, Gareth L.

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A Single Nucleotide Polymorphism in the MDM2 Promoter Attenuates the p53 Tumor Suppressor Pathway and Accelerates Tumor Formation in Humans von Bond, Gareth L., Hu, Wenwei, Bond, Elisabeth E., Robins, Harlan, Lutzker, Stuart G., Arva, Nicoleta C., Bargonetti, Jill, Bartel, Frank, Taubert, Helge, Wuerl, Peter, Onel, Kenan, Yip, Linwah, Hwang, Shih-Jen, Strong, Louise C., Lozano, Guillermina, Levine, Arnold J.

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New role of fat-free mass in cancer risk linked with genetic predisposition von Harris, Benjamin H. L., Di Giovannantonio, Matteo, Zhang, Ping, Harris, David A., Lord, Simon R., Allen, Naomi E., Maughan, Tim S., Bryant, Richard J., Harris, Adrian L., Bond, Gareth L., Buffa, Francesca M.

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MEF2 transcription factors are key regulators of sprouting angiogenesis von Sacilotto, Natalia, Chouliaras, Kira M, Nikitenko, Leonid L, Lu, Yao Wei, Fritzsche, Martin, Wallace, Marsha D, Nornes, Svanhild, García-Moreno, Fernando, Payne, Sophie, Bridges, Esther, Liu, Ke, Biggs, Daniel, Ratnayaka, Indrika, Herbert, Shane P, Molnár, Zoltán, Harris, Adrian L, Davies, Benjamin, Bond, Gareth L, Bou-Gharios, George, Schwarz, John J, De Val, Sarah

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A Polymorphic p53 Response Element in KIT Ligand Influences Cancer Risk and Has Undergone Natural Selection von Zeron-Medina, Jorge, Wang, Xuting, Repapi, Emmanouela, Campbell, Michelle R., Su, Dan, Castro-Giner, Francesc, Davies, Benjamin, Peterse, Elisabeth F.P., Sacilotto, Natalia, Walker, Graeme J., Terzian, Tamara, Tomlinson, Ian P., Box, Neil F., Meinshausen, Nicolai, De Val, Sarah, Bell, Douglas A., Bond, Gareth L.

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A Polymorphic Antioxidant Response Element Links NRF2/sMAF Binding to Enhanced MAPT Expression and Reduced Risk of Parkinsonian Disorders von Wang, Xuting, Campbell, Michelle R., Lacher, Sarah E., Cho, Hye-Youn, Wan, Ma, Crowl, Christopher L., Chorley, Brian N., Bond, Gareth L., Kleeberger, Steven R., Slattery, Matthew, Bell, Douglas A.

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A single nucleotide polymorphism in the MDM2 gene : From a molecular and cellular explanation to clinical effect von BOND, Gareth L, WENWEI HU, LEVINE, Arnold

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MDM2 SNP309 accelerates tumor formation in a gender-specific and hormone-dependent manner von BOND, Gareth L, HIRSHFIELD, Kim M, TOPPMEYER, Deborah, OFFIT, Kenneth, LEVINE, Arnold J, KIRCHHOFF, Tomas, ALEXE, Gabriella, BOND, Elisabeth E, ROBINS, Harlan, BARTEL, Frank, TAUBERT, Helge, WUERL, Peter, HAIT, William

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A High-Frequency Regulatory Polymorphism in the p53 Pathway Accelerates Tumor Development von Post, Sean M., Quintás-Cardama, Alfonso, Pant, Vinod, Iwakuma, Tomoo, Hamir, Amir, Jackson, James G., Maccio, Daniela R., Bond, Gareth L., Johnson, David G., Levine, Arnold J., Lozano, Guillermina

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Optimizing CRISPR/Cas9 Editing of Repetitive Single Nucleotide Variants von Usher, Inga, Ligammari, Lorena, Ahrabi, Sara, Hepburn, Emily, Connolly, Calum, Bond, Gareth L., Flanagan, Adrienne M., Cottone, Lucia

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Altered tumor formation and evolutionary selection of genetic variants in the human MDM4 oncogene von Atwal, Gurinder Singh, Kirchhoff, Tomas, Bond, Elisabeth E, Monagna, Marco, Menin, Chiara, Bertorelle, Roberta, Scaini, Maria Chiara, Bartel, Frank, Böhnke, Anja, Pempe, Christina, Gradhand, Elise, Hauptmann, Steffen, Offit, Kenneth, Levine, Arnold J, Bond, Gareth L

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A Chromatin-associated and Transcriptionally Inactive p53-Mdm2 Complex Occurs in mdm2 SNP309 Homozygous Cells von Arva, Nicoleta C., Gopen, Tamara R., Talbott, Kathryn E., Campbell, Latoya E., Chicas, Agustin, White, David E., Bond, Gareth L., Levine, Arnold J., Bargonetti, Jill

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iASPP mediates p53 selectivity through a modular mechanism fine-tuning DNA recognition von Chen, Shuo, Wu, Jiale, Zhong, Shan, Li, Yuntong, Zhang, Ping, Ma, Jingyi, Ren, Jingshan, Tan, Yun, Wang, Yunhao, Au, Kin Fai, Siebold, Christian, Bond, Gareth L., Chen, Zhu, Lu, Min, Jones, E. Yvonne, Lu, Xin

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Recent Natural Selection Identifies a Genetic Variant in a Regulatory Subunit of Protein Phosphatase 2A that Associates with Altered Cancer Risk and Survival von Lukasz F. Grochola, Alexei Vazquez, Elisabeth E. Bond, Peter Würl, Helge Taubert, Thomas H. Müller, Arnold J. Levine, Gareth L. Bond

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Germline and Somatic Genetic Variants in the p53 Pathway Interact to Affect Cancer Risk, Progression, and Drug Response von Zhang, Ping, Kitchen-Smith, Isaac, Xiong, Lingyun, Stracquadanio, Giovanni, Brown, Katherine, Richter, Philipp H., Wallace, Marsha D., Bond, Elisabeth, Sahgal, Natasha, Moore, Samantha, Nornes, Svanhild, De Val, Sarah, Surakhy, Mirvat, Sims, David, Wang, Xuting, Bell, Douglas A., Zeron-Medina, Jorge, Jiang, Yanyan, Ryan, Anderson J., Selfe, Joanna L., Shipley, Janet, Kar, Siddhartha, Pharoah, Paul D., Loveday, Chey, Jansen, Rick, Grochola, Lukasz F., Palles, Claire, Protheroe, Andrew, Millar, Val, Ebner, Daniel, Pagadala, Meghana, Blagden, Sarah P., Maughan, Timothy S., Domingo, Enric, Tomlinson, Ian, Turnbull, Clare, Carter, Hannah, Bond, Gareth L.

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Haplotype structure and selection of the MDM2 oncogene in humans von Atwal, Gurinder Singh, Bond, Gareth L, Metsuyanim, Sally, Papa, Moshe, Friedman, Eitan, Distelman-Menachem, Tal, Ben Asher, Edna, Lancet, Doron, Ross, David A, Sninsky, John, White, Tomas J, Levine, Arnold J, Yarden, Ronit

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Germline Pathogenic Variants Impact Clinicopathology of Advanced Lung Cancer von Mukherjee, Semanti, Bandlamudi, Chaitanya, Hellmann, Matthew D, Kemel, Yelena, Drill, Esther, Rizvi, Hira, Tkachuk, Kaitlyn, Khurram, Aliya, Walsh, Michael F, Zauderer, Marjorie G, Mandelker, Diana, Topka, Sabine, Zehir, Ahmet, Srinivasan, Preethi, Esai Selvan, Myvizhi, Carlo, Maria I, Cadoo, Karen A, Latham, Alicia, Hamilton, Jada G, Liu, Ying L, Lipkin, Steven M, Belhadj, Sami, Bond, Gareth L, Gümüş, Zeynep H, Klein, Robert J, Ladanyi, Marc, Solit, David B, Robson, Mark E, Jones, David R, Kris, Mark G, Vijai, Joseph, Stadler, Zsofia K, Amos, Christopher I, Taylor, Barry S, Berger, Michael F, Rudin, Charles M, Offit, Kenneth

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