649 MAINTENANCE OF REMISSION WITH TOFACITINIB IN PATIENTS WITH ULCERATIVE COLITIS: FINAL RESULTS OF A SUBPOPULATION ANALYSIS FROM AN OPEN-LABEL, LONG-TERM EXTENSION STUDY, OCTAVE O... von Colombel, Jean Frederic, Osterman, Mark T., Ibanez, Patricio, Vermeire, Séverine, Irving, Peter M., Gardiner, Sean M., Connelly, Susan B., Mundayat, Rajiv, Lawendy, Nervin, Su, Chinyu, Reinisch, Walter

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Tu1735 TREATMENT OUTCOME OF TOFACITINIB DOSE REDUCTION TO 5 MG TWICE DAILY (BID) VS REMAINING ON 10 MG BID IN PATIENTS WITH ULCERATIVE COLITIS WHO WERE IN STABLE REMISSION ON 10 MG... von Rubin, David T., Panés, Julián, Torres, Joana, Kobayashi, Taku, Su, Chinyu, Lawendy, Nervin, Modesto, Irene, Segovia, Michelle, Gardiner, Sean M., Wang, Wenjin, Vermeire, Severine

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Explainable AI reveals changes in skin microbiome composition linked to phenotypic differences von Carrieri, Anna Paola, Haiminen, Niina, Maudsley-Barton, Sean, Gardiner, Laura-Jayne, Murphy, Barry, Mayes, Andrew E., Paterson, Sarah, Grimshaw, Sally, Winn, Martyn, Shand, Cameron, Hadjidoukas, Panagiotis, Rowe, Will P. M., Hawkins, Stacy, MacGuire-Flanagan, Ashley, Tazzioli, Jane, Kenny, John G., Parida, Laxmi, Hoptroff, Michael, Pyzer-Knapp, Edward O.

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Stem cell transcriptome profiling via massive-scale mRNA sequencing von Cloonan, Nicole, Forrest, Alistair R R, Kolle, Gabriel, Gardiner, Brooke B A, Faulkner, Geoffrey J, Brown, Mellissa K, Taylor, Darrin F, Steptoe, Anita L, Wani, Shivangi, Bethel, Graeme, Robertson, Alan J, Perkins, Andrew C, Bruce, Stephen J, Lee, Clarence C, Ranade, Swati S, Peckham, Heather E, Manning, Jonathan M, McKernan, Kevin J, Grimmond, Sean M

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Long noncoding RNAs in mouse embryonic stem cell pluripotency and differentiation von Dinger, Marcel E, Amaral, Paulo P, Mercer, Tim R, Pang, Ken C, Bruce, Stephen J, Gardiner, Brooke B, Askarian-Amiri, Marjan E, Ru, Kelin, Soldà, Giulia, Simons, Cas, Sunkin, Susan M, Crowe, Mark L, Grimmond, Sean M, Perkins, Andrew C, Mattick, John S

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Role of Oral Rabies Vaccines in the Elimination of Dog-Mediated Human Rabies Deaths von Wallace, Ryan M, Cliquet, Florence, Fehlner-Gardiner, Christine, Fooks, Anthony R, Sabeta, Claude T, Setién, Alvaro Aguilar, Tu, Changchun, Vuta, Vlad, Yakobson, Boris, Yang, Dong-Kun, Brückner, Gideon, Freuling, Conrad M, Knopf, Lea, Metlin, Artem, Pozzetti, Patricia, Suseno, Pebi Purwo, Shadomy, Sean V, Torres, Gregorio, Vigilato, Marco Antonio Natal, Abela-Ridder, Bernadette, Müller, Thomas

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A global role for KLF1 in erythropoiesis revealed by ChIP-seq in primary erythroid cells von Tallack, Michael R, Whitington, Tom, Yuen, Wai Shan, Wainwright, Elanor N, Keys, Janelle R, Gardiner, Brooke B, Nourbakhsh, Ehsan, Cloonan, Nicole, Grimmond, Sean M, Bailey, Timothy L, Perkins, Andrew C

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A systematic review and meta-analysis investigating differences in chronic inflammation and adiposity before and after menopause von Pernoud, Laura E., Gardiner, Paul A., Fraser, Sean D., Dillon-Rossiter, Kirsten, Dean, Melinda M., Schaumberg, Mia A.

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Sexually Monomorphic Maps and Dimorphic Responses in Rat Genital Cortex von Lenschow, Constanze, Copley, Sean, Gardiner, Jayne M., Talbot, Zoe N., Vitenzon, Ariel, Brecht, Michael

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Regulated post-transcriptional RNA cleavage diversifies the eukaryotic transcriptome von Mercer, Tim R, Dinger, Marcel E, Bracken, Cameron P, Kolle, Gabriel, Szubert, Jan M, Korbie, Darren J, Askarian-Amiri, Marjan E, Gardiner, Brooke B, Goodall, Gregory J, Grimmond, Sean M, Mattick, John S

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MicroRNAs and their isomiRs function cooperatively to target common biological pathways von Cloonan, Nicole, Wani, Shivangi, Xu, Qinying, Gu, Jian, Lea, Kristi, Heater, Sheila, Barbacioru, Catalin, Steptoe, Anita L, Martin, Hilary C, Nourbakhsh, Ehsan, Krishnan, Keerthana, Gardiner, Brooke, Wang, Xiaohui, Nones, Katia, Steen, Jason A, Matigian, Nicholas A, Wood, David L, Kassahn, Karin S, Waddell, Nic, Shepherd, Jill, Lee, Clarence, Ichikawa, Jeff, McKernan, Kevin, Bramlett, Kelli, Kuersten, Scott, Grimmond, Sean M

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Phylogenomic Analysis of a 55.1-kb 19-Gene Dataset Resolves a Monophyletic Fusarium that Includes the Fusarium solani Species Complex von Geiser, David M, Al-Hatmi, Abdullah M S, Aoki, Takayuki, Arie, Tsutomu, Balmas, Virgilio, Barnes, Irene, Bergstrom, Gary C, Bhattacharyya, Madan K, Blomquist, Cheryl L, Bowden, Robert L, Brankovics, Balázs, Brown, Daren W, Burgess, Lester W, Bushley, Kathryn, Busman, Mark, Cano-Lira, José F, Carrillo, Joseph D, Chang, Hao-Xun, Chen, Chi-Yu, Chen, Wanquan, Chilvers, Martin, Chulze, Sofia, Coleman, Jeffrey J, Cuomo, Christina A, de Beer, Z Wilhelm, de Hoog, G Sybren, Del Castillo-Múnera, Johanna, Del Ponte, Emerson M, Diéguez-Uribeondo, Javier, Di Pietro, Antonio, Edel-Hermann, Véronique, Elmer, Wade H, Epstein, Lynn, Eskalen, Akif, Esposto, Maria Carmela, Everts, Kathryne L, Fernández-Pavía, Sylvia P, da Silva, Gilvan Ferreira, Foroud, Nora A, Fourie, Gerda, Frandsen, Rasmus J N, Freeman, Stanley, Freitag, Michael, Frenkel, Omer, Fuller, Kevin K, Gagkaeva, Tatiana, Gardiner, Donald M, Glenn, Anthony E, Gold, Scott E, Gordon, Thomas R, Gregory, Nancy F, Gryzenhout, Marieka, Guarro, Josep, Gugino, Beth K, Gutierrez, Santiago, Hammond-Kosack, Kim E, Harris, Linda J, Homa, Mónika, Hong, Cheng-Fang, Hornok, László, Huang, Jenn-Wen, Ilkit, Macit, Jacobs, Adriaana, Jacobs, Karin, Jiang, Cong, Jiménez-Gasco, María Del Mar, Kang, Seogchan, Kasson, Matthew T, Kazan, Kemal, Kennell, John C, Kim, Hye-Seon, Kistler, H Corby, Kuldau, Gretchen A, Kulik, Tomasz, Kurzai, Oliver, Laraba, Imane, Laurence, Matthew H, Lee, Theresa, Lee, Yin-Won, Lee, Yong-Hwan, Leslie, John F, Liew, Edward C Y, Lofton, Lily W, Logrieco, Antonio F, López-Berges, Manuel S, Luque, Alicia G, Lysøe, Erik, Ma, Li-Jun, Marra, Robert E, Martin, Frank N, May, Sara R, McCormick, Susan P, McGee, Chyanna, Meis, Jacques F, Migheli, Quirico, Mohamed Nor, N M I, Monod, Michel, Moretti, Antonio, Mostert, Diane, Mulè, Giuseppina

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Refining transcriptional programs in kidney development by integration of deep RNA-sequencing and array-based spatial profiling von Thiagarajan, Rathi D, Cloonan, Nicole, Gardiner, Brooke B, Mercer, Tim R, Kolle, Gabriel, Nourbakhsh, Ehsan, Wani, Shivangi, Tang, Dave, Krishnan, Keerthana, Georgas, Kylie M, Rumballe, Bree A, Chiu, Han S, Steen, Jason A, Mattick, John S, Little, Melissa H, Grimmond, Sean M

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Effectiveness of septoplasty compared to medical management in adults with obstruction associated with a deviated nasal septum: the NAIROS RCT von Carrie, Sean, Fouweather, Tony, Homer, Tara, O'Hara, James, Rousseau, Nikki, Rooshenas, Leila, Bray, Alison, Stocken, Deborah D, Ternent, Laura, Rennie, Katherine, Clark, Emma, Waugh, Nichola, Steel, Alison J, Dooley, Jemima, Drinnan, Michael, Hamilton, David, Lloyd, Kelly, Oluboyede, Yemi, Wilson, Caroline, Gardiner, Quentin, Kara, Naveed, Khwaja, Sadie, Leong, Samuel Chee, Maini, Sangeeta, Morrison, Jillian, Nix, Paul, Wilson, Janet A, Teare, M Dawn

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Improving Growth for Infants ≤1250 Grams Receiving an Exclusive Human Milk Diet von Huston, Robert K., Markell, Andrea M., McCulley, Elizabeth A., Gardiner, Stuart K., Sweeney, Sean L.

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Discovery of KIN-3248, An Irreversible, Next Generation FGFR Inhibitor for the Treatment of Advanced Tumors Harboring FGFR2 and/or FGFR3 Gene Alterations von Tyhonas, John S., Arnold, Lee D., Cox, Jason M., Franovic, Aleksandra, Gardiner, Elisabeth, Grandinetti, Kathryn, Kania, Robert, Kanouni, Toufike, Lardy, Matthew, Li, Chun, Martin, Eric S., Miller, Nichol, Mohan, Adithi, Murphy, Eric A., Perez, Michelle, Soroceanu, Liliana, Timple, Noel, Uryu, Sean, Womble, Scott, Kaldor, Stephen W.

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ZAP-70 expression is associated with enhanced ability to respond to migratory and survival signals in B-cell chronic lymphocytic leukemia (B-CLL) von Richardson, Sarah J., Matthews, Christine, Catherwood, Mark A., Alexander, H. Denis, Carey, B. Sean, Farrugia, Joanna, Gardiner, Anne, Mould, Sarah, Oscier, David, Copplestone, J. Adrian, Prentice, Archibald G.

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Abstract 18814: Glycoprotein VI is Critical for the Detection and Progression of Abdominal Aortic Aneurysms von Benson, Tyler W, Pike, Mindy M, Spuzzillo, Anthony, Hicks, Sarah, Pham, Michael, Bhandari, Rohan, Brunner, Seth, Wadding-Lee, Caris, Conrad, Kelsey, Russell, Hannah, Coughlin, Taylor, Aggarwal, Anu, Lyden, Sean, Mani, Kevin, Bjorck, Martin Gustaf, Wanhainen, Anders, Mix, Doran S, Lipworth, Loren, Robinson Cohen, Cassianne, Shim, Sharon, Edwards, Todd I, Tranter, Michael, Gardiner, Elizabeth, Mackman, Nigel, Cameron, Scott J, Owens, A. Phillip

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Deep-transcriptome and ribonome sequencing redefines the molecular networks of pluripotency and the extracellular space in human embryonic stem cells von Kolle, Gabriel, Shepherd, Jill L, Gardiner, Brooke, Kassahn, Karin S, Cloonan, Nicole, Wood, David L A, Nourbakhsh, Ehsan, Taylor, Darrin F, Wani, Shivangi, Chy, Hun S, Zhou, Qi, McKernan, Kevin, Kuersten, Scott, Laslett, Andrew L, Grimmond, Sean M

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Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes von Biankin, Andrew V., Waddell, Nicola, Kassahn, Karin S., Gingras, Marie-Claude, Miller, David K., Wilson, Peter J., Patch, Ann-Marie, Cowley, Mark J., Gardiner, Brooke B., Idrisoglu, Senel, Nourse, Craig, Nourbakhsh, Ehsan, Manning, Suzanne, Wani, Shivangi, Gongora, Milena, Pajic, Marina, Gill, Anthony J., Pinho, Andreia V., Holmes, Oliver, Leonard, Conrad, Taylor, Darrin, Xu, Qinying, Nones, Katia, Lynn Fink, J., Christ, Angelika, Bruxner, Tim, Cloonan, Nicole, Kolle, Gabriel, Newell, Felicity, Pinese, Mark, Humphris, Jeremy L., Kaplan, Warren, Jones, Marc D., Colvin, Emily K., Nagrial, Adnan M., Humphrey, Emily S., Chou, Angela, Chantrill, Lorraine A., Kench, James G., Lovell, Jessica A., Daly, Roger J., Merrett, Neil D., Toon, Christopher, Epari, Krishna, Nguyen, Nam Q., Barbour, Andrew, Zeps, Nikolajs, Kakkar, Nipun, Zhao, Fengmei, Qing Wu, Yuan, Muzny, Donna M., Fisher, William E., Charles Brunicardi, F., Hodges, Sally E., Reid, Jeffrey G., Drummond, Jennifer, Chang, Kyle, Han, Yi, Lewis, Lora R., Dinh, Huyen, Buhay, Christian J., Timms, Lee, Begley, Kimberly, Brown, Andrew, Pai, Deepa, Panchal, Ami, Buchner, Nicholas, Denroche, Robert E., Yung, Christina K., Serra, Stefano, Onetto, Nicole, Mukhopadhyay, Debabrata, Tsao, Ming-Sound, Shaw, Patricia A., Gallinger, Steven, Hruban, Ralph H., Maitra, Anirban, Iacobuzio-Donahue, Christine A., Schulick, Richard D., Morgan, Richard A., Lawlor, Rita T., Scardoni, Maria, Tortora, Giampaolo, Tempero, Margaret A., Mann, Karen M., Jenkins, Nancy A., Perez-Mancera, Pedro A., Adams, David J., Wessels, Lodewyk F. A., Rust, Alistair G., Stein, Lincoln D., Tuveson, David A., Musgrove, Elizabeth A., Hudson, Thomas J., Sutherland, Robert L., Wheeler, David A., Pearson, John V., McPherson, John D., Gibbs, Richard A., Grimmond, Sean M.

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