The Evaluation of Proximity Interventions: A Pilot Study von Sacchetti, Cleta, Martinelli, Stefano, Bassani, Marco, Atti, Anna Rita, Pascarella, Giuseppe, Gardenghi, Stefano

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Reducing TMPRSS6 ameliorates hemochromatosis and β-thalassemia in mice von Guo, Shuling, Casu, Carla, Gardenghi, Sara, Booten, Sheri, Aghajan, Mariam, Peralta, Raechel, Watt, Andy, Freier, Sue, Monia, Brett P, Rivella, Stefano

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Hepcidin inhibits Smad3 phosphorylation in hepatic stellate cells by impeding ferroportin-mediated regulation of Akt von Han, Chang Yeob, Koo, Ja Hyun, Kim, Sung Hoon, Gardenghi, Sara, Rivella, Stefano, Strnad, Pavel, Hwang, Se Jin, Kim, Sang Geon

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Intestinal HIF2α promotes tissue-iron accumulation in disorders of iron overload with anemia von Anderson, Erik R, Taylor, Matthew, Xue, Xiang, Ramakrishnan, Sadeesh K, Martin, Angelical, Xie, Liwei, Bredell, Bryce X, Gardenghi, Sara, Rivella, Stefano, Shah, Yatrik M

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β-Thalassemia: HiJAKing Ineffective Erythropoiesis and Iron Overload von Melchiori, Luca, Gardenghi, Sara, Rivella, Stefano

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Lack of IL6 Improves Recovery from Anemia of Inflammation Which Gets Hampered in Presence of Excess Iron von Sinha, Sayantani, Gupta, Ritama, Guerra, Amaliris, Mc Veigh, Paige, Gardenghi, Sara, Casu, Carla, Vinchi, Francesca, Rivella, Stefano

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Genetic loss of Tmprss6 alters terminal erythroid differentiation in a mouse model of β-thalassemia intermedia von Stagg, David B, Whittlesey, Rebecca L, Li, Xiuqi, Lozovatsky, Larisa, Gardenghi, Sara, Rivella, Stefano, Finberg, Karin E

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Macrophages support pathological erythropoiesis in polycythemia vera and β-thalassemia von Ramos, Pedro, Casu, Carla, Gardenghi, Sara, Breda, Laura, Crielaard, Bart J, Guy, Ella, Marongiu, Maria Franca, Gupta, Ritama, Levine, Ross L, Abdel-Wahab, Omar, Ebert, Benjamin L, Van Rooijen, Nico, Ghaffari, Saghi, Grady, Robert W, Giardina, Patricia J, Rivella, Stefano

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Non-imported malaria in Italy: paradigmatic approaches and public health implications following an unusual cluster of cases in 2017 von Boccolini, Daniela, Menegon, Michela, Di Luca, Marco, Toma, Luciano, Severini, Francesco, Marucci, Gianluca, D'Amato, Stefania, Caraglia, Anna, Maraglino, Francesco Paolo, Rezza, Giovanni, Romi, Roberto, Gradoni, Luigi, Severini, Carlo

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Therapeutic hemoglobin levels after gene transfer in β-thalassemia mice and in hematopoietic cells of β-thalassemia and sickle cells disease patients von Breda, Laura, Casu, Carla, Gardenghi, Sara, Bianchi, Nicoletta, Cartegni, Luca, Narla, Mohandas, Yazdanbakhsh, Karina, Musso, Marco, Manwani, Deepa, Little, Jane, Gardner, Lawrence B, Kleinert, Dorothy A, Prus, Eugenia, Fibach, Eitan, Grady, Robert W, Giardina, Patricia J, Gambari, Roberto, Rivella, Stefano

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Elucidating the Role of IL6 in Stress Erythropoiesis and in the Development of Anemia Under Inflammatory Conditions von Sinha, Sayantani, Gupta, Ritama, Zhang, Jianbing, Guerra, Amaliris, La, Ping, Gardenghi, Sara, Rivella, Stefano

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Modified activin receptor IIB ligand trap mitigates ineffective erythropoiesis and disease complications in murine β-thalassemia von Suragani, Rajasekhar N.V.S., Cawley, Sharon M., Li, Robert, Wallner, Samantha, Alexander, Mark J., Mulivor, Aaron W., Gardenghi, Sara, Rivella, Stefano, Grinberg, Asya V., Pearsall, R. Scott, Kumar, Ravindra

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Distinct roles for hepcidin and interleukin-6 in the recovery from anemia in mice injected with heat-killed Brucella abortus von Gardenghi, Sara, Renaud, Tom M., Meloni, Alessandra, Casu, Carla, Crielaard, Bart J., Bystrom, Laura M., Greenberg-Kushnir, Noa, Sasu, Barbra J., Cooke, Keegan S., Rivella, Stefano

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Isocitrate ameliorates anemia by suppressing the erythroid iron restriction response von Richardson, Chanté L, Delehanty, Lorrie L, Bullock, Grant C, Rival, Claudia M, Tung, Kenneth S, Kimpel, Donald L, Gardenghi, Sara, Rivella, Stefano, Goldfarb, Adam N

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Hepcidin as a therapeutic tool to limit iron overload and improve anemia in β-thalassemic mice von Gardenghi, Sara, Ramos, Pedro, Marongiu, Maria Franca, Melchiori, Luca, Breda, Laura, Guy, Ella, Muirhead, Kristen, Rao, Niva, Roy, Cindy N, Andrews, Nancy C, Nemeth, Elizabeta, Follenzi, Antonia, An, Xiuli, Mohandas, Narla, Ginzburg, Yelena, Rachmilewitz, Eliezer A, Giardina, Patricia J, Grady, Robert W, Rivella, Stefano

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A Double Knock out of Hepcidin and IL6 Demonstrates Independent Roles of the Two Genes in Anemia of Inflammation von Gupta, Ritama, Gardenghi, Sara, Bystrom, Lori, Chessa, Roberta, Rivella, Stefano

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Absence of Interleukin-6 Protects Murine Bone Marrow Erythropoiesis Under Inflammation, in a Process Reversible By Iron Mediated Reactive Oxygen Species Upregulation von Gupta, Ritama, Chessa, Roberta, Ping, La, Lo Presti, Vania, Gardenghi, Sara, Rivella, Stefano

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Enhanced erythropoiesis in Hfe-KO mice indicates a role for Hfe in the modulation of erythroid iron homeostasis von Ramos, Pedro, Guy, Ella, Chen, Nan, Proenca, Catia C., Gardenghi, Sara, Casu, Carla, Follenzi, Antonia, Van Rooijen, Nico, Grady, Robert W., de Sousa, Maria, Rivella, Stefano

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HMGB1 Mediates Anemia of Inflammation in Murine Sepsis Survivors von Valdés-Ferrer, Sergio I, Papoin, Julien, Dancho, Meghan E, Olofsson, Peder S, Li, Jianhua, Lipton, Jeffrey M, Avancena, Patricia, Yang, Huan, Zou, Yong-Rui, Chavan, Sangeeta S, Volpe, Bruce T, Gardenghi, Sara, Rivella, Stefano, Diamond, Betty, Andersson, Ulf, Steinberg, Bettie M, Blanc, Lionel, Tracey, Kevin J

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Ineffective erythropoiesis in β-thalassemia is characterized by increased iron absorption mediated by down-regulation of hepcidin and up-regulation of ferroportin von Gardenghi, Sara, Marongiu, Maria F., Ramos, Pedro, Guy, Ella, Breda, Laura, Chadburn, Amy, Liu, YiFang, Amariglio, Ninette, Rechavi, Gideon, Rachmilewitz, Eliezer A., Breuer, William, Cabantchik, Z. Ioav, Wrighting, Diedra M., Andrews, Nancy C., de Sousa, Maria, Giardina, Patricia J., Grady, Robert W., Rivella, Stefano

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