A randomized phase III trial comparing induction chemotherapy followed by chemoradiotherapy versus chemoradiotherapy alone as treatment of unresectable head and neck cancer von Hitt, R., Grau, J.J., López-Pousa, A., Berrocal, A., García-Girón, C., Irigoyen, A., Sastre, J., Martínez-Trufero, J., Brandariz Castelo, J.A., Verger, E., Cruz-Hernández, J.J., Almodóvar, C., Cortés-Funes, H., Escobar, Y., Fonseca-Sánchez, E., Galcerán, J.C., Guix, M., Isla-Casado, D., Jara-Sánchez, C., Leitão-Silva, M.R., Mel-Lorenzo, J.R., Pastor-Borgoñón, M., Pastor-Gaitán, P., Rodríguez-Jaráiz, A., Millán, J.M., Satrustegui-Galdona, J., Moreno, M., Estefanía, E., Santiago, E., García, J.J.

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First-line bevacizumab and capecitabine–oxaliplatin in elderly patients with mCRC: GEMCAD phase II BECOX study von Feliu, J, Salud, A, Safont, M J, García-Girón, C, Aparicio, J, Vera, R, Serra, O, Casado, E, Jorge, M, Escudero, P, Bosch, C, Bohn, U, Pérez-Carrión, R, Carmona, A, Martínez-Marín, V, Maurel, J

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Epidermal growth factor receptor activating mutations in Spanish gefitinib-treated non-small-cell lung cancer patients von Cortes-Funes, H., Gomez, C., Rosell, R., Valero, P., Garcia-Giron, C., Velasco, A., Izquierdo, A., Diz, P., Camps, C., Castellanos, D., Alberola, V., Cardenal, F., Gonzalez-Larriba, J. L., Vieitez, J. M., Maeztu, I., Sanchez, J. J., Queralt, C., Mayo, C., Mendez, P., Moran, T., Taron, M.

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Capecitabine and bevacizumab as first-line treatment in elderly patients with metastatic colorectal cancer von Feliu, J, Safont, M J, Salud, A, Losa, F, García-Girón, C, Bosch, C, Escudero, P, López, R, Madroñal, C, Bolaños, M, Gil, M, Llombart, A, Castro-Carpeño, J, González-Barón, M

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Docetaxel combined with irinotecan or 5-fluorouracil in patients with advanced oesophago-gastric cancer: a randomised phase II study von Roy, A, Cunningham, D, Hawkins, R, Sörbye, H, Adenis, A, Barcelo, J-R, Lopez-Vivanco, G, Adler, G, Canon, J-L, Lofts, F, Castanon, C, Fonseca, E, Rixe, O, Aparicio, J, Cassinello, J, Nicolson, M, Mousseau, M, Schalhorn, A, D'Hondt, L, Kerger, J, Hossfeld, D K, Garcia Giron, C, Rodriguez, R, Schoffski, P, Misset, J-L

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No evidence for JAK2 V617F mutation in colorectal cancer von Herreros-Villanueva, M., Garcia-Girón, C., Er, T.-K.

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227 Predictive serum biomarkers in metastatic colorectal cancer patients treated in the BECOX trial with oxaliplatin-capecitabine (CAPOX) plus bevacizumab (GEMCAD 09-01) von Pineda Losada, E, Salud, A, Vila-Navarro, E, Safont, M.J, Garcia-Giron, C, Aparicio, J, Vera, R, Escudero, M.P, Casado, E, Bosch, C, Bohn, U, Perez Carrion, R.M, Carmona Bayonas, A, Ayuso, J.R, Ripolles, T, Bouzas, R, Gironella, M, Garcia-Albeniz, X, Feliu, J, Maurel, J

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First-line treatment outcomes according to cfDNA analysis of RAS mutation status in metastatic colorectal cancer (mCRC) patients (pts): PERSEIDA study von García Alfonso, P, Valladares-Ayerbes, M, Muñoz Luengo, J, Pimentel, P, Viéitez, J M, Cruz Hernandez, J J, Llanos, M, Garcia Girón, C, Salud Salvia, A, Lloansí Vila, A

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Cancer chemotherapy reduces plasma total polyphenols and total antioxidants capacity in colorectal cancer patients von Santiago-Arteche, R., Muñiz, P., Cavia-Saiz, M., Garcia-Giron, C., García-Gonzalez, M., Llorente-Ayala, Beatriz, Corral, M. J. Coma-del

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Randomized phase III study of 3-weekly versus weekly docetaxel in pretreated advanced non-small-cell lung cancer: a Spanish Lung Cancer Group trial von Camps, C., Massuti, B., Jiménez, A., Maestu, I., Gómez, R. García, Isla, D., González, J. L., Almenar, D., Blasco, A., Rosell, R., Carrato, A., Viñolas, N., Batista, N., Girón, C. García, Galán, A., López, M., Blanco, R., Provencio, M., Diz, P., Felip, E.

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913P Characterisation of genomic biomarkers of response to cetuximab versus cisplatin in concomitance with radiotherapy in locally advanced squamous head and neck cancer von Redondo González, J.C., Olivares Hernandez, A., Garcia Hernandez, J.L., Mesia Nin, R., Rubio Casadevall, J., Garcia Giron, C., Iglesias Docampo, L., Carral Maseda, A., Taberna Sanz, M., Vázquez Fernández, S., Corchete Sánchez, L.A., Gestoso Uzal, N., González Sarmiento, R., Fonseca Sánchez, E., Cruz Hernandez, J.J., del Barco Morillo, E.

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914P The landscape of somatic copy number alterations of head and neck squamous cell carcinoma across different anatomic sites von Redondo González, J.C., Olivares Hernandez, A., Garcia Hernandez, J.L., Mesia Nin, R., Rubió-Casadevall, J., Garcia Giron, C., Iglesias Docampo, L., Carral Maseda, A., Taberna Sanz, M., Vázquez Fernández, S., Corchete Sánchez, L.A., Gestoso Uzal, N., González Sarmiento, R., Fonseca Sánchez, E., Cruz Hernandez, J.J., del Barco Morillo, E.

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Long-term outcomes of induction chemotherapy followed by chemoradiotherapy vs chemoradiotherapy alone as treatment of unresectable head and neck cancer: follow-up of the Spanish He... von Hitt, R., Iglesias, L., López-Pousa, A., Berrocal-Jaime, A., Grau, J. J., García-Girón, C., Martínez-Trufero, J., Guix, M., Lambea-Sorrosal, J., del Barco-Morillo, E., León-Vintró, X., Cunquero-Tomas, A. J., Baste, N., Ocaña, A., Cruz-Hernández, J. J.

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Comparison of plasma ctDNA and tissue/cytology-based techniques for the detection of EGFR mutation status in advanced NSCLC: Spanish data subset from ASSESS von Arriola, E., Paredes-Lario, A., García-Gomez, R., Diz-Tain, P., Constenla, M., García-Girón, C., Márquez, G., Reck, M., López-Vivanco, G.

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Phase II study of carboplatin and 1-h intravenous etoposide and paclitaxel in a novel sequence as first-line treatment of patients with small-cell lung cancer von Vieitez, J.M, Valladares, M, Gracia, M, Gonzalez-Barón, M, Martı́n, G, Mel, J.R, Rodrı́guez, R, Constenla, M, Gómez Aldavarı́, J.L, Domı́nguez, S, Dorta, J, Garcı́a-Girón, C, López, R, Sevilla, I, Esteban, E, Antón, L.M, Peláez, I, López, E, Lacave, A.J

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Treatment of patients with advanced gastric carcinoma with the combination of etoposide plus oral tegafur modulated by uracil and leucovorin: A phase II study of the ONCOPAZ Cooper... von Feliu, J., Barón, M. González, García‐Girón, C., Espinosa, E., García‐Alfonso, P., Belón, J., Blanco, E., Garrido, P., Ordóñez, A., Gómez‐Navarro, J., Zamora, P.

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892P Hedgehog (Hh) activation in neuroendocrine neoplasms (NENs) von Blanco Abad, C., Saiz Lopez, P., Alcaraz Ortega, R., Garcia Toro, E., Garcia Giron, C., Muñiz Rodriguez, P., Catoya Villa, J.L., de la Torre Lazaro, S., de Frutos Gonzalez, B., Rodriguez Ledesma, I., Gutierrez Perez, C., Vela, M., Pumares Gonzalez, M., Espinosa Cabria, N., Crespo Herrero, G.

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701P Genomic alteration relationships with toxicity to TPF induction chemotherapy in head and neck squamous cell carcinoma patients participating in a clinical trial von Olivares Hernandez, A., García, J.L., Alonso, N., Corchete Sánchez, L.A., Perez García, J., Mesia Nin, R., Rubió-Casadevall, J., Garcia Giron, C., Iglesias Docampo, L., Carral Maseda, A., Taberna Sanz, M., Vazquez, S., Gómez Muñoz, A., del Barco, E., González Sarmiento, R., Cruz Hernandez, J.J.

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692P Copy number alterations and response to radiotherapy + cisplatin vs radiotherapy + cetuximab after docetaxel-cisplatin-fluorouracil induction chemotherapy in patients with loc... von García, J.L., Olivares Hernandez, A., Alonso, N., Corchete Sánchez, L.A., Fernandez-Mateos, J., Perez García, J., Hernández, M.A., Seijas Tamayo, R., Mesia Nin, R., Rubió-Casadevall, J., Garcia Giron, C., Iglesias, L., Carral Maseda, A., Adansa Klain, J.C., Taberna Sanz, M., Vazquez, S., Gómez Muñoz, A., del Barco, E., González Sarmiento, R., Cruz Hernandez, J.J.

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P76.42 OsimertinibTreatment in Non-Small Cell Lung Cancer (NSCLC) EGFR-T790M+. Activity in Patients with CNS Metastases. OSIREX von Terrasa, J., Garrido, P., Garcia Campelo, R., Aparisi, F., Diz, P., Aguiar, D., Garcia Giron, C., Hidalgo, J., Aguado De La Rosa, C., Garcia Gonzalez, J.J., Esteban, E., Gómez Aldavari, L., Moran, T., Juan, O., Chara, L.E., Martí, J.L., Castro, R. Lopez, Ortega Granados, A.L., Martinez Moreno, N., Coves, J., Sánchez Peña, A.M., Bosch-Barrera, J., Provencio, M.

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