Unraveling the clinicopathological and molecular changes induced by neoadjuvant chemotherapy and endocrine therapy in hormone receptor-positive/HER2-low and HER2-0 breast cancer von Schettini, F., Nucera, S., Brasó-Maristany, F., De Santo, I., Pascual, T., Bergamino, M., Galván, P., Conte, B., Seguí, E., García Fructuoso, I., Gómez Bravo, R., Rivera, P., Rodríguez, A.B., Martínez-Sáez, O., Ganau, S., Sanfeliu, E., González-Farre, B., Vidal Losada, M.J., Adamo, B., Cebrecos, I., Mension, E., Oses, G., Jares, P., Vidal-Sicart, S., Mollà, M., Muñoz, M., Prat, A.

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CN91 Toxicities in breast cancer patients undergoing neoadjuvant immune checkpoint inhibitor therapy: Insights from a nurse practitioner perspective von Garcia, A.B. Rodriguez, Torralba, Y., Walbaum, B., Solis, E. Segui, Saez, O. Martinez, Bartolome, N., Alatamirano, M., Carcelero, E., Riu, G., Schettini, F., García-Fructuoso, I., Bravo, R. Gómez, Rivera, P.R., Pascual, T., Adamo, B., Losada, M.J. Vidal, Munoz, M., Prat, A., Domenech, A.

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Prognostic value of intrinsic subtypes in hormone-receptor-positive metastatic breast cancer: systematic review and meta-analysis von Schettini, F., Martínez-Sáez, O., Falato, C., De Santo, I., Conte, B., Garcia-Fructuoso, I., Gomez-Bravo, R., Seguí, E., Chic, N., Brasó-Maristany, F., Paré, L., Vidal, M., Adamo, B., Muñoz, M., Pascual, T., Ciruelos, E., Perou, C.M., Carey, L.A., Prat, A.

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Identifying predictors of treatment response and molecular changes induced by neoadjuvant chemotherapy and endocrine therapy in hormone receptor-positive/HER2-negative breast cance... von Schettini, F, Brasó-Maristany, F, Pascual, T, Lorman-Carbó, N, Nucera, S, Bergamino, M, Galván, P, Conte, B, Seguí, E, García Fructuoso, I, Gómez Bravo, R, Rodríguez, A B, Martínez-Sáez, O, Chic, N, Vidal, M, Adamo, B, González-Farre, B, Sanfeliu, E, Cebrecos, I, Mensión, E, Oses, G, Locci, M, Mollà, M, Ganau, S, Jares, P, Vidal-Sicart, S, Muñoz, M, Prat, A

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8P Evaluating HER2DX pCR-Score and MRI response in predicting pathologic complete response (pCR) to anti-HER2 neoadjuvant chemotherapy (CT) in early-stage HER2-positive (HER2+) bre... von Pascual, T., Martínez-Sáez, O., Brunet, L. Pare, Javierre, G. Villacampa, Vivancos, A., Bargalló, X., Ganau, S., Úbeda, B., Sitges, C., Losada, M.J. Vidal, Adamo, B., Gomez-Bravo, R., García-Fructuoso, I., Schettini, F., Solis, E. Segui, Conte, B., Gonzalez, P. Villagrasa, Torres, E. Sanfeliu, Prat, A., Brasó-Maristany, F.

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22P Unveiling biological and prognostic differences among premenopausal patients with hormone receptor-positive HER2-negative (HR+/HER2-) breast cancer von Walbaum, B., Chic, N., Bruñol, C. Crous, Sola, J., Martínez-Sáez, O., Gomez-Bravo, R., Solís, E. Seguí, García-Fructuoso, I., Pascual, T., Schettini, F., Adamo, B., Munoz, M., Torres, E. Sanfeliu, Conte, B., Galván, P., Brasó-Maristany, F., Prat, A., Losada, M.J. Vidal

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Gestational diabetes mellitus in a cohort of HIV‐1 infected women von González‐Tomé, MI, Ramos Amador, JT, Guillen, S, Solís, I, Fernández‐Ibieta, M, Muñoz, E, Almeda, J, Rojano, X, Rojo, P, Nieto, O

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1115P Beyond classic hereditary neuroendocrine tumors (NET) syndromes von Castillo Manzano, C., Guillén, P., Vidal, J.M. Brunet, Lazaro, C., Ruffinelli, J.C.C., Santos Vivas, C., Torrent, F., Lleuger, R., Garcia-Fructuoso, I., Teule, A.

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284P Clinical and molecular characteristics of early-stage triple-negative breast cancer (eTNBC) patients with germline pathogenic variants in homologous recombination repair genes von Hernandez, A. Rodriguez, Conte, B., Maristany, F. Braso, Pastor, B., Fratini, B., Walbaum, B., Potrony, M., Moreno, L., Grau, E., Torres, E. Sanfeliu, Saez, O. Martinez, Solis, E. Segui, Bravo, R. Gómez, Fructuoso, I. Garcia, Losada, M.J. Vidal, Ramon y Cajal, T., Munoz, M., Balaguer, F., Prat, A., Adamo, B.

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49P A ctDNA tool for identifying ESR1-mutated biology in ESR1-non-mutated hormone receptor-positive (HR+) metastatic breast cancer (MBC) von Fructuoso, I. Garcia, Martínez-Sáez, O., Pardo, F., Vega León, M.D.R., Matito, J., Brunet, L. Pare, Castillo, O., Javierre, G. Villacampa, Galván, P., Odegaard, J., Gonzalez, P. Villagrasa, Parker, J., Perou, C.M., Vivancos, A., Prat, A., Brasó-Maristany, F.

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11P Influence of ctDNA variant allele frequency (VAF) on survival outcomes in metastatic breast cancer (MBC) von Fructuoso, I. Garcia, Martínez-Sáez, O., Conte, B., Gomez-Bravo, R., Solis, E. Segui, Schettini, F., Pascual, T., Adamo, B., Ruiz, I. Victoria, Moreno, D., Angelats, L., Coronel, D.S. Pesantez, Galván, P., Olmos, R., Faull, I., Odegaard, J., Munoz, M., Prat, A., Brasó-Maristany, F., Losada, M.J. Vidal

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12P Updated findings from the first prospective HER2DX clinical decision impact study on early-stage HER2-positive (HER2+) breast cancer (BC) von Martínez-Sáez, O., Marin, M., Hernández-Illán, E., Martinez-Puchol, A.I., Jares, P., Puig-Butille, J.A., Torres, E. Sanfeliu, Losada, M.J. Vidal, Adamo, B., Pascual, T., Schettini, F., Conte, B., Bravo, R. Gómez, Fructuoso, I. Garcia, Chic, N., Solís, E. Seguí, Walbaum, B., Rivera, P.R., Brunet, L. Pare, Munoz, M.

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16P Determinants of response to short preoperative endocrine therapy (pET) in hormone receptor-positive and HER2-negative (HR+/HER2-) early breast cancer (EBC) von Bravo, R. Gómez, Walbaum, B., Schettini, F., Solís, E. Seguí, Martínez-Sáez, O., Fructuoso, I. Garcia, Galván, P., Pascual, T., Conte, B., Rivera, P.R., Gonzalez-Farre, B., Losada, M.J. Vidal, Adamo, B., Torres, E. Sanfeliu, Blasco, P., Castillo, O., Rodriguez, A.B., Brasó-Maristany, F., Prat, A., Munoz, M.

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14P Assessing the predictive value of HER2DX pCR-score for pathologic complete response (pCR) in early-stage HER2-positive (HER2+) breast cancer (BC) under real-world conditions von Martínez-Sáez, O., Marin, M., Brunet, L. Pare, Javierre, G. Villacampa, Vivancos, A., Losada, M.J. Vidal, Adamo, B., Bravo, R. Gómez, Fructuoso, I. Garcia, Pascual, T., Chic, N., Rivera, P.R., Schettini, F., Solís, E. Seguí, Conte, B., Gonzalez, P. Villagrasa, Torres, E. Sanfeliu, Brasó-Maristany, F., Prat, A., Munoz, M.

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Clinical portrait of the SARS-Cov-2 epidemic in European cancer patients von Pinato, D, Zambelli, A, Aguilar-Company, J, Bower, M, Sng, C, Salazar, R, Bertuzzi, A, Brunet, J, Mesia, R, Segui, E, Biello, F, Generali, D, Grisanti, S, Rizzo, G, Libertini, M, Maconi, A, Harbeck, N, Vincenzi, B, Bertulli, R, Ottaviani, D, Carbo, A, Bruna, R, Benafif, S, Marrari, A, Wuerstlein, R, Carmona-Garcia, MC, Chopra, N, Tondini, C, Mirallas, O, Tovazzi, V, Betti, M, Provenzano, S, Fotia, V, Cruz, CA, Dalla Pria, A, D'Avanzo, F, Evans, J, Saoudi-Gonzalez, N, Felip, E, Galazi, M, Garcia-Fructuoso, I, Lee, AJX, Newsom-Davis, T, Patriarca, A, Illescas, D, Reyes, R, Dileo, P, Sharkey, R, Wong, YNS, Ferrante, D, Marco-Hernandez, J, Sureda, A, Maluquer, C, Ruiz-Camps, I, Gaidano, G, Rimassa, L, Chiudinelli, L, Izuzquiza, M, Cabirta, A, Franchi, M, Santoro, A, Prat, A, Tabernero, J, Gennari, A

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8P First decision impact study of HER2DX in patients (pts) with HER2-positive (HER2+) early breast cancer von Saez, O. Martinez, Brasó-Maristany, F., Marín-Aguilera, M., Losada, M.J. Vidal, Adamo, B., Pascual, T., Schettini, F., Conte, B., Chic, N., Bravo, R. Gomez, Fructuoso, I. Garcia, Solis, E. Segui, Galván, P., Hernández-Illán, E., Jares, P., Puig-Butille, J.A., Torres, E. Sanfeliu, Brunet, L. Pare, Gonzalez, P. Villagrasa, Munoz, M.

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10P HER2 loss and PAM50 dynamics after neoadjuvant therapy (NAT) in HER2-positive (HER2+) early breast cancer (BC) von Morganti, S., Brasó-Maristany, F., Rey, M., Goberna, G., Pascual, T., Schettini, F., Conte, B., Bravo, R. Gomez, Fructuoso, I. Garcia, Solis, E. Segui, Galván, P., Torres, E. Sanfeliu, Gonzalez-Farre, B., Losada, M.J. Vidal, Adamo, B., Munoz, M., Lin, N., Tolaney, S.M., Prat, A., Saez, O. Martinez

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Specialist palliative and end-of-life care for patients with cancer and SARS-CoV-2 infection: a European perspective von Soosaipillai, G, Wu, A, Dettorre, GM, Diamantis, N, Chester, J, Moss, C, Aguilar-Company, J, Bower, M, Sng, C, Salazar, R, Brunet, J, Jones, E, Mesia, R, Jackson, A, Mukherjee, U, Sita-Lumsden, A, Segui, E, Ottaviani, D, Carbo, A, Benafif, S, Wuerstlein, R, Carmona, C, Chopra, N, Cruz, C, Swallow, J, Saoudi, N, Felip, E, Galazi, M, Garcia-Fructuoso, I, Lee, A, Newsom-Davis, T, Wong, S, Sureda, A, Maluquer, C, Ruiz-Camps, I, Cabirta, A, Prat, A, Gennari, A, Ferrante, D, Tabernero, J, Russell, B, Van Hemelrijck, M, Dolly, S, Pinato, D

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Presenting features and early mortality from SARS-CoV-2 infection in cancer patients during the initial stage of the COVID-19 pandemic in Europe von Pinato, DJ, Lee, AJX, Biello, F, Seguí, E, Aguilar-Company, J, Carbó, A, Bruna, R, Bower, M, Rizzo, G, Benafif, S, Carmona, C, Chopra, N, Cruz, CA, D'Avanzo, F, Evans, JS, Galazi, M, Garcia-Fructuoso, I, Dalla Pria, A, Newsom-Davis, T, Ottaviani, D, Patriarca, A, Reyes, R, Sharkey, R, Sng, CCT, Wong, YNS, Ferrante, D, Scotti, L, Avanzi, GC, Bellan, M, Castello, LM, Marco-Hernández, J, Mollà, M, Pirisi, M, Ruiz-Camps, I, Sainaghi, PP, Gaidano, G, Brunet, J, Tabernero, J, Prat, A, Gennari, A

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Specialist palliative and end-of-life care for patients with cancer and SARS-CoV-2 infection: a European perspective von Soosaipillai, G, Wu, A, Dettorre, GM, Diamantis, N, Chester, J, Moss, C, Aguilar-Company, J, Bower, M, Sng, CCT, Salazar, R, Brunet, J, Jones, E, Mesia, R, Jackson, A, Mukherjee, U, Sita-Lumsden, A, Seguí, E, Ottaviani, D, Carbó, A, Benafif, S, Würstlein, R, Carmona, C, Chopra, N, Cruz, CA, Swallow, J, Saoudi, N, Felip, E, Galazi, M, Garcia-Fructuoso, I, Lee, AJX, Newsom-Davis, T, Wong, YNS, Sureda, A, Maluquer, C, Ruiz-Camps, I, Cabirta, A, Prat, A, Loizidou, A, Gennari, A, Ferrante, D, Tabernero, J, Russell, B, Van Hemelrijck, M, Dolly, S, Hulbert-Williams, NJ, Pinato, DJ, Mollà, M, Reyes, R, Marco-Hernández, J, Bruna, R, Biello, F, Patriarca, A, Zambelli, A, Tondini, C, Fotia, V, Chiudinelli, L, Franchi, M, Generali, D, Grisanti, S, Tovazzi, V, Bertuzzi, A, Marrari, A, Seeva, P, Dileo, P, Rizzo, G, Libertini, M, Maconi, A, Betti, M, Provenzano, S, Harbeck, N, Vincenzi, B, Bertulli, R, Liñan, R, Roqué, A, Mirallas, O, García-Illescas, D, Scotti, L, Dalla Pria, A, D’Avanzo, F, Martinez, M, Evans, JS, Sharkey, R, Rimassa, L, Santoro, A, Gaidano, G, Izuzquiza, M

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