Positive Allosteric Modulation of CB1 Cannabinoid Receptor Signaling Enhances Morphine Antinociception and Attenuates Morphine Tolerance Without Enhancing Morphine- Induced Depende... von Slivicki, Richard A., Iyer, Vishakh, Mali, Sonali S., Garai, Sumanta, Thakur, Ganesh A., Crystal, Jonathon D., Hohmann, Andrea G.

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Positive allosteric modulation of type 1 cannabinoid receptors reduces spike-and-wave discharges in Genetic Absence Epilepsy Rats from Strasbourg von Roebuck, Andrew J., Greba, Quentin, Smolyakova, Anna-Maria, Alaverdashvili, Mariam, Marks, Wendie N., Garai, Sumanta, Baglot, Samantha L., Petrie, Gavin, Cain, Stuart M., Snutch, Terrance P., Thakur, Ganesh A., Hill, Matthew N., Howland, John G., Laprairie, Robert B.

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Antipsychotic potential of the type 1 cannabinoid receptor positive allosteric modulator GAT211: preclinical in vitro and in vivo studies von McElroy, Dan L., Roebuck, Andrew J., Scott, Gavin A., Greba, Quentin, Garai, Sumanta, Denovan-Wright, Eileen M., Thakur, Ganesh A., Laprairie, Robert B., Howland, John G.

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Pharmacological evaluation of enantiomerically separated positive allosteric modulators of cannabinoid 1 receptor, GAT591 and GAT593 von Brandt, Asher L., Garai, Sumanta, Zagzoog, Ayat, Hurst, Dow P., Stevenson, Lesley A., Pertwee, Roger G., Imler, Gregory H., Reggio, Patricia H., Thakur, Ganesh A., Laprairie, Robert B.

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A protecting group free and scalable approach towards total synthesis of (−)-venlafaxine von Chavan, Subhash P., Pawar, Kailash P., Garai, Sumanta

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The type 1 cannabinoid receptor positive allosteric modulators GAT591 and GAT593 reduce spike-and-wave discharges in Genetic Absence Epilepsy Rats from Strasbourg von McElroy, Dan L., Roebuck, Andrew J., Greba, Quentin, Garai, Sumanta, Brandt, Asher L., Yilmaz, Orhan, Cain, Stuart M., Snutch, Terrance P., Thakur, Ganesh A., Laprairie, Robert B., Howland, John G.

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A highly diastereoselective total synthesis of (±)-heritonin and (±)-heritol von Chavan, Subhash P., Garai, Sumanta, Kalkote, Uttam R.

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Total synthesis of bioactive drimane–epoxyquinol hybrid natural products: macrophorin A, 4′-oxomacrophorin A, and 1′-epi-craterellin A von Garai, Sumanta, Mehta, Goverdhan

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Scalable, One-Pot, Microwave-Accelerated Tandem Synthesis of Unsymmetrical Urea Derivatives von Kulkarni, Abhijit R, Garai, Sumanta, Thakur, Ganesh A

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Polyamidoamine dendrimers-based nanomedicine for combination therapy with siRNA and chemotherapeutics to overcome multidrug resistance von Pan, Jiayi, Mendes, Livia P., Yao, Momei, Filipczak, Nina, Garai, Sumanta, Thakur, Ganesh A., Sarisozen, Can, Torchilin, Vladimir P.

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Allosteric Agonism of α7 Nicotinic Acetylcholine Receptors: Receptor Modulation Outside the Orthosteric Site von Gulsevin, Alican, Papke, Roger L, Stokes, Clare, Garai, Sumanta, Thakur, Ganesh A, Quadri, Marta, Horenstein, Nicole A

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Allosterically Potentiated alpha 7 Nicotinic Acetylcholine Receptors: Reduced Calcium Permeability and Current-Independent Control of Intracellular Calcium von Miller, Douglas R., Khoshbouei, Habibeh, Garai, Sumanta, Cantwell, Lucas N., Stokes, Clare, Thakur, Ganesh, Papke, Roger L.

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Macroscopic and Microscopic Activation of α7 Nicotinic Acetylcholine Receptors by the Structurally Unrelated Allosteric Agonist-Positive Allosteric Modulators (ago-PAMs) B-973B and... von Quadri, Marta, Garai, Sumanta, Thakur, Ganesh A., Stokes, Clare, Gulsevin, Alican, Horenstein, Nicole A., Papke, Roger L.

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The endocannabinoid system impacts seizures in a mouse model of Dravet syndrome von Anderson, Lyndsey L., Doohan, Peter T., Hawkins, Nicole A., Bahceci, Dilara, Garai, Sumanta, Thakur, Ganesh A., Kearney, Jennifer A., Arnold, Jonathon C.

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Differing Activity Profiles of the Stereoisomers of 2,3,5,6TMP-TQS, a Putative Silent Allosteric Modulator of alpha 7 nAChR von Papke, Roger L., Garai, Sumanta, Stokes, Clare, Horenstein, Nicole A., Zimmerman, Arthur D., Abboud, Khalil A., Thakur, Ganesh A.

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Application of Fluorine- and Nitrogen-Walk Approaches: Defining the Structural and Functional Diversity of 2‑Phenylindole Class of Cannabinoid 1 Receptor Positive Allosteric Modula... von Garai, Sumanta, Kulkarni, Pushkar M, Schaffer, Peter C, Leo, Luciana M, Brandt, Asher L, Zagzoog, Ayat, Black, Tallan, Lin, Xiaoyan, Hurst, Dow P, Janero, David R, Abood, Mary E, Zimmowitch, Anaelle, Straiker, Alex, Pertwee, Roger G, Kelly, Melanie, Szczesniak, Anna-Maria, Denovan-Wright, Eileen M, Mackie, Ken, Hohmann, Andrea G, Reggio, Patricia H, Laprairie, Robert B, Thakur, Ganesh A

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The small molecule GAT1508 activates brain-specific GIRK1/2 channel heteromers and facilitates conditioned fear extinction in rodents von Xu, Yu, Cantwell, Lucas, Molosh, Andrei I., Plant, Leigh D., Gazgalis, Dimitris, Fitz, Stephanie D., Dustrude, Erik T., Yang, Yuchen, Kawano, Takeharu, Garai, Sumanta, Noujaim, Sami F., Shekhar, Anantha, Logothetis, Diomedes E., Thakur, Ganesh A.

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Design, synthesis, and pharmacological profiling of cannabinoid 1 receptor allosteric modulators: Preclinical efficacy of C2-group GAT211 congeners for reducing intraocular pressur... von Garai, Sumanta, Schaffer, Peter C., Laprairie, Robert B., Janero, David R., Pertwee, Roger G., Straiker, Alex, Thakur, Ganesh A.

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Allosterically Potentiated α7 Nicotinic Acetylcholine Receptors: Reduced Calcium Permeability and Current-Independent Control of Intracellular Calcium von Miller, Douglas R, Khoshbouei, Habibeh, Garai, Sumanta, Cantwell, Lucas N, Stokes, Clare, Thakur, Ganesh, Papke, Roger L

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Asymmetric total synthesis of (−)-venlafaxine using an organocatalyst von Chavan, Subhash P., Garai, Sumanta, Pawar, Kailash P.

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