Megabase-scale deletion using CRISPR/Cas9 to generate a fully haploid human cell line von Essletzbichler, Patrick, Konopka, Tomasz, Santoro, Federica, Chen, Doris, Gapp, Bianca V, Kralovics, Robert, Brummelkamp, Thijn R, Nijman, Sebastian M B, Bürckstümmer, Tilmann

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A generic strategy for CRISPR-Cas9-mediated gene tagging von Lackner, Daniel H., Carré, Alexia, Guzzardo, Paloma M., Banning, Carina, Mangena, Ramu, Henley, Tom, Oberndorfer, Sarah, Gapp, Bianca V., Nijman, Sebastian M.B., Brummelkamp, Thijn R., Bürckstümmer, Tilmann

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HACE1 Prevents Lung Carcinogenesis via Inhibition of RAC-Family GTPases von Kogler, Melanie, Tortola, Luigi, Negri, Gian Luca, Leopoldi, Alexandra, El-Naggar, Amal M, Mereiter, Stefan, Gomez-Diaz, Carlos, Nitsch, Roberto, Tortora, Davide, Kavirayani, Anoop M, Gapp, Bianca V, Rao, Shuan, Uribesalgo, Iris, Hoffmann, David, Cikes, Domagoj, Novatchkova, Maria, Williams, David A, Trent, Jeffrey M, Ikeda, Fumiyo, Daugaard, Mads, Hagelkruys, Astrid, Sorensen, Poul H, Penninger, Josef M

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Cathepsin-mediated Necrosis Controls the Adaptive Immune Response by Th2 (T helper type 2)-associated Adjuvants von Jacobson, Lee S., Lima, Heriberto, Goldberg, Michael F., Gocheva, Vasilena, Tsiperson, Vladislav, Sutterwala, Fayyaz S., Joyce, Johanna A., Gapp, Bianca V., Blomen, Vincent A., Chandran, Kartik, Brummelkamp, Thijn R., Diaz-Griffero, Felipe, Brojatsch, Jürgen

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Parallel reverse genetic screening in mutant human cells using transcriptomics von Gapp, Bianca V, Konopka, Tomasz, Penz, Thomas, Dalal, Vineet, Bürckstümmer, Tilmann, Bock, Christoph, Nijman, Sebastian MB

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Quantitative genetic screening reveals a Ragulator-FLCN feedback loop that regulates the mTORC1 pathway von De Zan, Erica, van Stiphout, Ruud, Gapp, Bianca V, Blomen, Vincent A, Brummelkamp, Thijn R, Nijman, Sebastian M B

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A chemical-genetic screen reveals a mechanism of resistance to PI3K inhibitors in cancer von Muellner, Markus K, Uras, Iris Z, Gapp, Bianca V, Kerzendorfer, Claudia, Smida, Michal, Lechtermann, Hannelore, Craig-Mueller, Nils, Colinge, Jacques, Duernberger, Gerhard, Nijman, Sebastian M B

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Genome-wide genetic screening with chemically mutagenized haploid embryonic stem cells von Forment, Josep V, Herzog, Mareike, Coates, Julia, Konopka, Tomasz, Gapp, Bianca V, Nijman, Sebastian M, Adams, David J, Keane, Thomas M, Jackson, Stephen P

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Synthetic Lethal Vulnerabilities of Cancer von Fece de la Cruz, Ferran, Gapp, Bianca V, Nijman, Sebastian M.B

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A chemical genetic screen reveals a resistance mechanism to PI3K inhibitors in cancer von Muellner, Markus K, Uras, Iris Z, Gapp, Bianca V, Kerzendorfer, Claudia, Smida, Michal, Lechtermann, Hannelore, Craig-Mueller, Nils, Colinge, Jacques, Duernberger, Gerhard, Nijman, Sebastian MB

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Parallel Reverse Genetic Screening In Mutant Human Cells Using Transcriptomics - Data And Analyses von Gapp, Bianca V, Konopka, Tomasz, Penz, Thomas, Dalal, Vineet, Burckstummer, Tilmann, Bock, Christoph, Nijman, Sebastian MB

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